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Navigating the open innovation paradox: an integrative framework for adopting open innovation in pharmaceutical R&D in developing countries

Author

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  • Bhawani Bhatnagar

    (University of Strathclyde)

  • Viktor Dörfler

    (University of Strathclyde)

  • Jillian MacBryde

    (University of Strathclyde)

Abstract

In this paper, we combine evidence from eight Indian pharmaceutical firms with extant literature and global best practices to conceptualize an integrative framework addressing the open innovation paradox (OIP), i.e., the tension between intellectual protection and openness. Firms in developing countries face additional challenges in the adoption of open innovation, such as the prevalence of open science norms, weak technology transfer systems, and mistrust between universities and industry; therefore, they employ open innovation selectively for pharmaceutical research. Prior research has examined the strategies to resolve OIP in the context of developed countries; the integrative framework proposed in this paper describes strategies for resolving the OIP in the context of developing countries. This framework illuminates the coping processes of the case firms and provides guidelines to uplift and accelerate the adoption of open innovation strategies in developing countries’ pharmaceutical sectors, and thus provides value to both theory and praxis.

Suggested Citation

  • Bhawani Bhatnagar & Viktor Dörfler & Jillian MacBryde, 2023. "Navigating the open innovation paradox: an integrative framework for adopting open innovation in pharmaceutical R&D in developing countries," The Journal of Technology Transfer, Springer, vol. 48(6), pages 2204-2248, December.
  • Handle: RePEc:kap:jtecht:v:48:y:2023:i:6:d:10.1007_s10961-022-09958-6
    DOI: 10.1007/s10961-022-09958-6
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    1. David J. Teece, 2003. "Competition, Cooperation, and Innovation Organizational Arrangements for Regimes of Rapid Technological Progress," World Scientific Book Chapters, in: Essays In Technology Management And Policy Selected Papers of David J Teece, chapter 16, pages 447-474, World Scientific Publishing Co. Pte. Ltd..
    2. David J. TEECE, 2008. "Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy," World Scientific Book Chapters, in: The Transfer And Licensing Of Know-How And Intellectual Property Understanding the Multinational Enterprise in the Modern World, chapter 5, pages 67-87, World Scientific Publishing Co. Pte. Ltd..
    3. Foege, J. Nils & Lauritzen, Ghita Dragsdahl & Tietze, Frank & Salge, Torsten Oliver, 2019. "Reconceptualizing the paradox of openness: How solvers navigate sharing-protecting tensions in crowdsourcing," Research Policy, Elsevier, vol. 48(6), pages 1323-1339.
    4. Fred Y. Ye & Susan S. Yu & Loet Leydesdorff, 2013. "The Triple Helix of university‐industry‐government relations at the country level and its dynamic evolution under the pressures of globalization," Journal of the American Society for Information Science and Technology, Association for Information Science & Technology, vol. 64(11), pages 2317-2325, November.
    5. Oliver Gassmann & Alexander Schuhmacher & Max von Zedtwitz & Gerrit Reepmeyer, 2018. "Leading Pharmaceutical Innovation," Springer Books, Springer, edition 3, number 978-3-319-66833-8, December.
    6. Jason Owen-Smith & Massimo Riccaboni & Fabio Pammolli & Walter W. Powell, 2002. "A Comparison of U.S. and European University-Industry Relations in the Life Sciences," Management Science, INFORMS, vol. 48(1), pages 24-43, January.
    7. Cappa, Francesco & Oriani, Raffaele & Pinelli, Michele & De Massis, Alfredo, 2019. "When does crowdsourcing benefit firm stock market performance?," Research Policy, Elsevier, vol. 48(9), pages 1-1.
    8. Stephan, Paula E., 2010. "The Economics of Science," Handbook of the Economics of Innovation, in: Bronwyn H. Hall & Nathan Rosenberg (ed.), Handbook of the Economics of Innovation, edition 1, volume 1, chapter 0, pages 217-273, Elsevier.
    9. Fischer, Bruno Brandão & Schaeffer, Paola Rücker & Vonortas, Nicholas S., 2019. "Evolution of university-industry collaboration in Brazil from a technology upgrading perspective," Technological Forecasting and Social Change, Elsevier, vol. 145(C), pages 330-340.
    10. Arora, Ashish & Athreye, Suma & Huang, Can, 2016. "The paradox of openness revisited: Collaborative innovation and patenting by UK innovators," Research Policy, Elsevier, vol. 45(7), pages 1352-1361.
    11. Manish Srivastava & Tang Wang, 2015. "When does selling make you wiser? Impact of licensing on Chinese firms’ patenting propensity," The Journal of Technology Transfer, Springer, vol. 40(4), pages 602-628, August.
    12. Owen-Smith, Jason, 2003. "From separate systems to a hybrid order: accumulative advantage across public and private science at Research One universities," Research Policy, Elsevier, vol. 32(6), pages 1081-1104, June.
    13. Bronwyn H. Hall & Albert N. Link & John T. Scott, 2003. "Universities as Research Partners," The Review of Economics and Statistics, MIT Press, vol. 85(2), pages 485-491, May.
    14. Elias G. Carayannis & Dirk Meissner, 2017. "Glocal targeted open innovation: challenges, opportunities and implications for theory, policy and practice," The Journal of Technology Transfer, Springer, vol. 42(2), pages 236-252, April.
    15. Ashish Arora & Alfonso Gambardella & Laura Magazzini & Fabio Pammolli, 2009. "A Breath of Fresh Air? Firm Type, Scale, Scope, and Selection Effects in Drug Development," Management Science, INFORMS, vol. 55(10), pages 1638-1653, October.
    16. Nancy T. Gallini, 2002. "The Economics of Patents: Lessons from Recent U.S. Patent Reform," Journal of Economic Perspectives, American Economic Association, vol. 16(2), pages 131-154, Spring.
    17. Dahlander, Linus & Gann, David M. & Wallin, Martin W., 2021. "How open is innovation? A retrospective and ideas forward," Research Policy, Elsevier, vol. 50(4).
    18. T. Theeranattapong & D. Pickernell & C. Simms, 2021. "Systematic literature review paper: the regional innovation system-university-science park nexus," The Journal of Technology Transfer, Springer, vol. 46(6), pages 2017-2050, December.
    19. Suma Athreye & Dinar Kale & Shyama V. Ramani, 2009. "Experimentation with strategy and the evolution of dynamic capability in the Indian pharmaceutical sector," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 18(4), pages 729-759, August.
    20. Kafouros, Mario I. & Forsans, Nicolas, 2012. "The role of open innovation in emerging economies: Do companies profit from the scientific knowledge of others?," Journal of World Business, Elsevier, vol. 47(3), pages 362-370.
    21. Bruno Brandão Fischer & Paola Rücker Schaeffer & Nicholas S. Vonortas & Sérgio Queiroz, 2018. "Quality comes first: university-industry collaboration as a source of academic entrepreneurship in a developing country," The Journal of Technology Transfer, Springer, vol. 43(2), pages 263-284, April.
    22. Bronwyn H. Hall & Albert N. Link & John T. Scott, 2003. "Universities as Research Partners," The Review of Economics and Statistics, MIT Press, vol. 85(2), pages 485-491, May.
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