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Citations for "Scale, Scope and Spillovers: The Determinants of Research Productivity in Drug Discovery"

by Rebecca Henderson & Iain Cockburn

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  1. Benjamin F. Jones, 2005. "The burden of knowledge and the ‘death of the Renaissance man’: Is innovation getting harder?," Proceedings, Federal Reserve Bank of San Francisco.
  2. Leten, Bart & Kelchtermans, Stijn & Belderbos, Ren, 2010. "Internal Basic Research, External Basic Research and the Technological Performance of Pharmaceutical Firms," Working Papers 2010/12, Hogeschool-Universiteit Brussel, Faculteit Economie en Management.
  3. Laura Magazzini & Fabio Pammolli & Massimo Riccaboni & Maria Alessandra Rossi, 2009. "Patent Disclosure and R&D Competition in Pharmaceuticals," ROCK Working Papers 053, Department of Computer and Management Sciences, University of Trento, Italy, revised 11 Jun 2009.
  4. Cassiman, Bruno & Veugelers, Reinhilde & Zuniga, P, 2006. "Science linkages and innovation performance: An analysis on CIS-3 firms in Belgium," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/120607, Katholieke Universiteit Leuven.
  5. Soh, Pek-Hooi, 2003. "The role of networking alliances in information acquisition and its implications for new product performance," Journal of Business Venturing, Elsevier, vol. 18(6), pages 727-744, November.
  6. Frank R. Lichtenberg, 2001. "The Allocation of Publicly Funded Biomedical Research," NBER Chapters, in: Medical Care Output and Productivity, pages 565-590 National Bureau of Economic Research, Inc.
  7. Audretsch, David B & Lehmann, Erik E, 2005. "Entrepreneurial Access and Absorption of Knowledge Spillovers: Strategic Board and Managerial Composition for Competitive Advantage," CEPR Discussion Papers 5335, C.E.P.R. Discussion Papers.
  8. Daron Acemoglu & Joshua Linn, 2004. "Market Size in Innovation: Theory and Evidence from the Pharmaceutical Industry," The Quarterly Journal of Economics, MIT Press, vol. 119(3), pages 1049-1090, August.
  9. Banri ITO & Tatsufumi YAMAGATA, 2007. "Who Develops Innovations In Medicine For The Poor? Trends In Patent Applications Related To Medicines For Hiv/Aids, Tuberculosis, Malaria, And Neglected Diseases," The Developing Economies, Institute of Developing Economies, vol. 45(2), pages 141-171.
  10. Josh Lerner & Alexander Tsai, 2000. "Do Equity Financing Cycles Matter? Evidence from Biotechnology Alliances," NBER Working Papers 7464, National Bureau of Economic Research, Inc.
  11. Cassiman, Bruno & Veugelers, Reinhilde, 1998. "R&D cooperation and spillovers: some empirical evidence," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/102907, Katholieke Universiteit Leuven.
  12. Gilsing, Victor & Nooteboom, Bart & Vanhaverbeke, Wim & Duysters, Geert & van den Oord, Ad, 2008. "Network embeddedness and the exploration of novel technologies: Technological distance, betweenness centrality and density," Research Policy, Elsevier, vol. 37(10), pages 1717-1731, December.
  13. Andy Cosh & Xiaolan Fu & Alan Hughes, 2005. "Management characteristics, collaboration and innovative efficiency: evidence from UK survey data," ESRC Centre for Business Research - Working Papers wp311, ESRC Centre for Business Research.
  14. Häussler, Carolin, 2006. "Can’t Buy Me Rights! The Contractual Structure of Asymmetrical Inter-firm Collaborations," Discussion Paper Series of SFB/TR 15 Governance and the Efficiency of Economic Systems 189, Free University of Berlin, Humboldt University of Berlin, University of Bonn, University of Mannheim, University of Munich.
  15. Ashish Arora & Sharon Belenzon & Luis A. Rios, 2011. "The Organization of R&D in American Corporations: The Determinants and Consequences of Decentralization," NBER Working Papers 17013, National Bureau of Economic Research, Inc.
  16. Cassiman, Bruno & Pérez-Castrillo, David, 2000. "Endogenizing know-how flows through the nature of R&D investments," IESE Research Papers D/428, IESE Business School.
  17. Vanhaverbeke, W.P.M. & Beerkens, B.E. & Duysters, G.M., 2003. "Explorative and exploitative learning strategies in technology-based alliance networks," Eindhoven Center for Innovation Studies (ECIS) working paper series 03.22, Eindhoven Center for Innovation Studies (ECIS).
  18. Rockett, Katharine, 2012. "Perspectives on the knowledge-based society: An introduction to the special issue," Economics - The Open-Access, Open-Assessment E-Journal, Kiel Institute for the World Economy, vol. 6(35), pages =1-22.
  19. Lionel Nesta, 2005. "Knowledge and Productivity in the World's Largest Manufacturing Corporations Level:Panel Data analysis on Compustat and Patent data," Documents de Travail de l'OFCE 2005-17, Observatoire Francais des Conjonctures Economiques (OFCE).
  20. Lee G. Branstetter & Chirantan Chatterjee & Matthew Higgins, 2011. "Regulation and Welfare: Evidence from Paragraph IV Generic Entry in the Pharmaceutical Industry," NBER Working Papers 17188, National Bureau of Economic Research, Inc.
  21. Bartzokas, Anthony & Yarime, Masaru, 1997. "Technology Trends in Pollution-Intensive Industries: A Review of Sectoral Trends," Discussion Papers 06, United Nations University, Institute for New Technologies.
  22. José García-Quevedo & Gabriele Pellegrino & Marco Vivarelli, 2011. "The determinants of YICs’ R&Dactivity," Working Papers 2011/31, Institut d'Economia de Barcelona (IEB).
  23. Takalo, Tuomas & Tanayama, Tanja & Toivanen, Otto, 2008. "Evaluating innovation policy: a structural treatment effect model of R&D subsidies," Research Discussion Papers 7/2008, Bank of Finland.
  24. Bertoni, Fabio & Tykvová, Tereza, 2013. "Which form of venture capital is most supportive of innovation? Evidence from European biotechnology companies," FZID Discussion Papers 69-2013, University of Hohenheim, Center for Research on Innovation and Services (FZID).
  25. Henderson, Rebecca. & Cockburn, Iain., 1994. "Measuring competence? : exploring firm effects in pharmaceutical research," Working papers 3712-94., Massachusetts Institute of Technology (MIT), Sloan School of Management.
  26. Lee G. Branstetter & Mariko Sakakibara, 2002. "When Do Research Consortia Work Well and Why? Evidence from Japanese Panel Data," American Economic Review, American Economic Association, vol. 92(1), pages 143-159, March.
  27. Santamara, Llus & Nieto, Mara Jess & Barge-Gil, Andrs, 2009. "Beyond formal R&D: Taking advantage of other sources of innovation in low- and medium-technology industries," Research Policy, Elsevier, vol. 38(3), pages 507-517, April.
  28. Karpaty, Patrik & Tingvall, Patrik Gustavsson, 2011. "Offshoring and Home Country R&D," Working Paper Series in Economics and Institutions of Innovation 254, Royal Institute of Technology, CESIS - Centre of Excellence for Science and Innovation Studies.
  29. Van de Vrande, Vareska & Vanhaverbeke, Wim & Duysters, Geert, 2009. "Additivity and complementarity in external technology sourcing: The added value of corporate venture capital investments," MPRA Paper 26419, University Library of Munich, Germany, revised 2010.
  30. Giulio Bottazzi & Angelo Secchi, 2006. "Explaining the Distribution of Firm Growth Rates," RAND Journal of Economics, The RAND Corporation, vol. 37(2), pages 235-256, Summer.
  31. Cassiman, Bruno & Veugelers, Reinhilde & Arts, Sam, 2011. "How to capture value from linking to science-driven basic research: boundary crossing inventors and partnerships," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/326213, Katholieke Universiteit Leuven.
  32. Nicola Lacetera, 2000. "Corporate Governance and the Governance of Innovation: the Case of Pharmaceutical Industry," KITeS Working Papers 122, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Dec 2000.
  33. Catherine Matraves, 1998. "Market Structure, R&D and Advertising in the Pharmaceutical Industry," CIG Working Papers FS IV 98-17, Wissenschaftszentrum Berlin (WZB), Research Unit: Competition and Innovation (CIG).
  34. Alfonso Gambardella & Marco Giarratana, 2004. "Chandlerian Firms vs. Entrepreneurship," LEM Papers Series 2004/12, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
  35. Tsuyoshi Nakamura, 1999. "The Role of R&D Diversification in Exploiting Knowledge Spillover: Evidence from Major Japanese Chemical and Pharmaceutical Companies," CIRJE F-Series CIRJE-F-66, CIRJE, Faculty of Economics, University of Tokyo.
  36. Andre Jungmittag, 2004. "Innovations, technological specialisation and economic growth in the EU," European Economy - Economic Papers 199, Directorate General Economic and Monetary Affairs (DG ECFIN), European Commission.
  37. Callaert, Julie & Van Looy, Bart & Foray, D & Debackere, Koenraad, 2007. "Combining the production and the valorization of academic research: A qualitative investigation of enacted mechanisms," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/120602, Katholieke Universiteit Leuven.
  38. Marcela Miozzo & Lori DiVito & Panos Desyllas, 2011. "Cross-border acquisitions of science-based firms: Their effect on innovation in the acquired firm and the local science," DRUID Working Papers 11-17, DRUID, Copenhagen Business School, Department of Industrial Economics and Strategy/Aalborg University, Department of Business Studies.
  39. Bharat N. Anand & Alexander Galetovic, 2000. "Weak Property Rights and Holdup in R&D," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 9(4), pages 615-642, December.
  40. Ajay Agrawal & Iain M. Cockburn, 2002. "University Research, Industrial R&D, and the Anchor Tenant Hypothesis," NBER Working Papers 9212, National Bureau of Economic Research, Inc.
  41. Michael J. Orlando, 2002. "Measuring R & D spillovers : on the importance of geographic and technological proximity," Research Working Paper RWP 02-06, Federal Reserve Bank of Kansas City.
  42. Chavas, Jean-Paul & Kim, Kwansoo, 2010. "Economies of diversification: A generalization and decomposition of economies of scope," International Journal of Production Economics, Elsevier, vol. 126(2), pages 229-235, August.
  43. Nooteboom, Bart & Van Haverbeke, Wim & Duysters, Geert & Gilsing, Victor & van den Oord, Ad, 2007. "Optimal cognitive distance and absorptive capacity," Research Policy, Elsevier, vol. 36(7), pages 1016-1034, September.
  44. Gaétan de Rassenfosse, 2013. "Do Firms Face a Trade-Off between the Quantity and the Quality of Their Inventions?," Melbourne Institute Working Paper Series wp2013n06, Melbourne Institute of Applied Economic and Social Research, The University of Melbourne.
  45. James D. Adams, 2004. "Industrial R&D Laboratories: Windows on Black Boxes?," Rensselaer Working Papers in Economics 0419, Rensselaer Polytechnic Institute, Department of Economics.
  46. Schwartz, Eduardo S., 2002. "Patents and R& D as Real Options," University of California at Los Angeles, Anderson Graduate School of Management qt86b1n43k, Anderson Graduate School of Management, UCLA.
  47. Veugelers, Reinhilde & Callaert, Julie & Song, Xiaoyan & Van Looy, Bart, 2011. "The participation of universities in technology development: do creation and use coincide? An empirical investigation on the level of national innovation systems," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/327124, Katholieke Universiteit Leuven.
  48. Steven Casper & Catherine Matraves, 1997. "Corporate Governance and Firm Strategy in the Pharmaceutical Industry," CIG Working Papers FS IV 97-20, Wissenschaftszentrum Berlin (WZB), Research Unit: Competition and Innovation (CIG).
  49. Tuomas Takalo & Tanja Tanayama & Otto Toivanen, 2005. "Selection Or Self-Rejection? Applications Into A Treatment," Industrial Organization 0510002, EconWPA.
  50. Gambardella, Alfonso & Orsenigo, Luigi & Pammolli, Fabio, 2000. "Global Competitiveness in Pharmaceuticals: A European Perspective," MPRA Paper 15965, University Library of Munich, Germany.
  51. Mahmood, Ishtiaq P. & Mitchell, Will, 2002. "Two Faces: Effects of Business Groups on Innovation in Emerging Economies," CEI Working Paper Series 2002-14, Center for Economic Institutions, Institute of Economic Research, Hitotsubashi University.
  52. Toivanen, Otto & Waterson, Michael, 2013. "The effect of department size on quality of research in science: Evidence from the UK research assessment exercise," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/391779, Katholieke Universiteit Leuven.
  53. Elena Cefis, 2008. "The Impact of M&A on Technology Sourcing Strategies," LEM Papers Series 2008/25, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
  54. Waheed, Abdul, 2011. "Size, competition, and innovative activities: a developing world perspective," UNU-MERIT Working Paper Series 052, United Nations University, Maastricht Economic and social Research and training centre on Innovation and Technology.
  55. Boris Lokshin & René Belderbos & Martin Carree, 2008. "The Productivity Effects of Internal and External R&D: Evidence from a Dynamic Panel Data Model," Oxford Bulletin of Economics and Statistics, Department of Economics, University of Oxford, vol. 70(3), pages 399-413, 06.
  56. James D. Adams & J. Roger Clemmons & Paula E. Stephan, 2006. "How Rapidly Does Science Leak Out?," Rensselaer Working Papers in Economics 0612, Rensselaer Polytechnic Institute, Department of Economics.
  57. Elena Cefis & Anna Sabidussi & Hans Schenk, 2007. "Do Mergers of Potentially Dominant Firms foster Innovation? An Empirical Analysis for the Manufacturing Sector," Working Papers 07-20, Utrecht School of Economics.
  58. Paul A. Gompers, 2002. "Corporations and the financing of innovation: The corporate venturing experience," Economic Review, Federal Reserve Bank of Atlanta, issue Q4, pages 1-17.
  59. Lopez, Henry & Vanhaverbeke, Wim, 2009. "How innovation intermediaries are shaping the technology market? An analysis of their business model," MPRA Paper 20458, University Library of Munich, Germany, revised 2010.
  60. James W Hughes & Michael J Moore & Edward A Snyder, 2003. "Napsterizing Pharmaceuticals: Access, Innovation and Consumer Welfare," Levine's Working Paper Archive 618897000000000555, David K. Levine.
  61. Gerald Marschke & Jinyoung Kim & Sangjoon John Lee, 2004. "Research Scientist Productivity and Firm Size: Evidence from Panel Data on Investors," Discussion Papers 04-06, University at Albany, SUNY, Department of Economics.
  62. Wilfried Zidorn & Marcus Wagner, 2012. "Too Much of a Good Thing: The Role of Alliance Portfolio Diversity for Innovation Output in the Biotechnology Industry," DRUID Working Papers 12-10, DRUID, Copenhagen Business School, Department of Industrial Economics and Strategy/Aalborg University, Department of Business Studies.
  63. Lionel Nesta, 2004. "Knowledge and Productivity in the World's Largest Manufacturing Corporations," SPRU Working Paper Series 119, SPRU - Science and Technology Policy Research, University of Sussex.
  64. David Collis & David Young & Michael Goold, 2010. "International Differences in the Size and Roles of Corporate Headquarters: An Empirical Examination," Harvard Business School Working Papers 10-044, Harvard Business School.
  65. Mahlich, Jörg C. & Roediger-Schluga, Thomas, 2006. "The Determinants of Pharmaceutical R&D Expenditures: Evidence from Japan," UNU-MERIT Working Paper Series 015, United Nations University, Maastricht Economic and social Research and training centre on Innovation and Technology.
  66. Wim Vanhaverbeke & Victor Gilsing & Bonnie Beerkens & Geert Duysters, 2009. "The Role of Alliance Network Redundancy in the Creation of Core and Non-core Technologies," Journal of Management Studies, Wiley Blackwell, vol. 46(2), pages 215-244, 03.
  67. TAKECHI Kazutaka, 2008. "International Strategic Alliances for Local Market Entry: Direct Launches versus Marketing Alliances in Pharmaceuticals," Discussion papers 08022, Research Institute of Economy, Trade and Industry (RIETI).
  68. Vanhaverbeke, W. & Beerkens, B. & Duysters, G., 2001. "Technological capability building through networking strategies within high-tech industries," Eindhoven Center for Innovation Studies (ECIS) working paper series 01.15, Eindhoven Center for Innovation Studies (ECIS).
  69. Ren� Belderbos & Leo Sleuwaegen & Reinhilde Veugelers, 2010. "Market Integration and Technological Leadership in Europe," European Economy - Economic Papers 403, Directorate General Economic and Monetary Affairs (DG ECFIN), European Commission.
  70. Lee G. Branstetter & Mariko Sakakibara, 2000. "When Do Research Consortia Work Well and Why? Evidence from Japanese Panel Data," NBER Working Papers 7972, National Bureau of Economic Research, Inc.
  71. Hauser, John R., 1996. "The role of mathematical models in the study of product development," Working papers #148-96. Working paper (S, Massachusetts Institute of Technology (MIT), Sloan School of Management.
  72. Brian Jacob & Lars Lefgren, 2007. "The Impact of Research Grant Funding on Scientific Productivity," NBER Working Papers 13519, National Bureau of Economic Research, Inc.
  73. Luigi Orsenigo & Fabio Pammolli & Massimo Riccaboni, 1999. "Competencies, Technological Change and Network Dynamics. The case of the bio-pharmaceutical industry," LEM Papers Series 1999/13, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
  74. Cassiman, Bruno & Veugelers, Reinhilde, 1997. "Complementarity between technology make and buy in innovation strategies: evidence from Belgian manufacturing firms," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/102908, Katholieke Universiteit Leuven.
  75. Stefano Brusoni & Paola Criscuolo & Aldo Geuna, 2005. "The knowledge bases of the world's largest pharmaceutical groups: what do patent citations to non-patent literature reveal?," Economics of Innovation and New Technology, Taylor and Francis Journals, vol. 14(5), pages 395-415.
  76. Eduardo S. Schwartz, 2003. "Patents and R&D as Real Options," NBER Working Papers 10114, National Bureau of Economic Research, Inc.
  77. Giulio Bottazzi & Tatiana Plotnikova, 2010. "Productivity and Heterogeneous Knowledge: Exploring the Relationship in a Sample of Drug Developers," Jena Economic Research Papers 2010-044, Friedrich-Schiller-University Jena, Max-Planck-Institute of Economics.
  78. Iain Cockburn & Rebecca Henderson & Scott Stern, 1999. "Balancing Incentives: The Tension Between Basic and Applied Research," NBER Working Papers 6882, National Bureau of Economic Research, Inc.
  79. Oscar Alfranca, 2005. "Private R&D and Spillovers in European Agriculture," International Advances in Economic Research, Springer, vol. 11(2), pages 201-213, May.
  80. Lee Branstetter & Mariko Sakakibara, 1997. "Japanese Research Consortia: A Microeconometric Analysis of Industrial Policy," NBER Working Papers 6066, National Bureau of Economic Research, Inc.
  81. Josh Lerner & Robert P. Merges, 1997. "The Control of Strategic Alliances: An Empirical Analysis of Biotechnology Collaborations," NBER Working Papers 6014, National Bureau of Economic Research, Inc.
  82. Patricia M. Danzon & Sean Nicholson & Nuno Sousa Pereira, 2003. "Productivity in Pharmaceutical Biotechnology R&D: The Role of Experience and Alliances," NBER Working Papers 9615, National Bureau of Economic Research, Inc.
  83. Olena Senyuta & Kresimir Zigic, 2012. "Managing Spillovers: An Endogenous Sunk Cost Approach," CERGE-EI Working Papers wp472, The Center for Economic Research and Graduate Education - Economic Institute, Prague.
  84. Pilar Beneito & María E. Rochina-Barrachina & Amparo Sanchis, 2013. "Learning through experience in Research & Development: an empirical analysis with Spanish firms," Working Papers 1302, Department of Applied Economics II, Universidad de Valencia.
  85. Ashish Arora & Alfonso Gambardella, 1996. "Domestic Markets and International Competitiveness," Industrial Organization 9605001, EconWPA.
  86. Dietmar Harhoff, 1997. "Incentives to Innovate: A Structural Model of Oligopoly (available only in German!)," CIG Working Papers FS IV 97-09, Wissenschaftszentrum Berlin (WZB), Research Unit: Competition and Innovation (CIG).
  87. J. P. Francois & F. Favre & S. Negassi, 2002. "Competence and Organization: Two Drivers of Innovation," Economics of Innovation and New Technology, Taylor and Francis Journals, vol. 11(3), pages 249-270.
  88. Emmanuel Duguet & Stéphanie Monjon, 2004. "Is innovation persistent at the firm Level . An econometric examination comparing the propensity score and regression methods," Cahiers de la Maison des Sciences Economiques v04075, Université Panthéon-Sorbonne (Paris 1).
  89. Ornaghi, Carmine, 2006. "Mergers and innovation: the case of the pharmaceutical industry," Discussion Paper Series In Economics And Econometrics 0605, Economics Division, School of Social Sciences, University of Southampton.
  90. Lee Branstetter & Reiko Aoki, 2005. "Is Academic Science Raising Innovative Productivity? Theory and Evidence from Firm-Level Data," Hi-Stat Discussion Paper Series d05-86, Institute of Economic Research, Hitotsubashi University.
  91. Kuo-Feng Huang & Chwo-Ming Yu, 2011. "The effect of competitive and non-competitive R&D collaboration on firm innovation," The Journal of Technology Transfer, Springer, vol. 36(4), pages 383-403, August.
  92. Rivera, Rene & Sampedro, Jose Luis & Dutrenit, Gabriela & Ekboir, Javier Mario & Vera-Cruz, Alexandre O., 2009. "How productive are academic researchers in agriculture-related sciences? The Mexican case," UNU-MERIT Working Paper Series 038, United Nations University, Maastricht Economic and social Research and training centre on Innovation and Technology.
  93. Robert S. Gibbons, 2010. "Inside Organizations: Pricing, Politics, and Path Dependence," Levine's Working Paper Archive 661465000000000249, David K. Levine.
  94. Benjamin F. Jones, 2005. "The Burden of Knowledge and the 'Death of the Renaissance Man': Is Innovation Getting Harder?," NBER Working Papers 11360, National Bureau of Economic Research, Inc.
  95. Michael J. Orlando, 2000. "On the importance of geographic and technological proximity for R&D spillovers : an empirical investigation," Research Working Paper RWP 00-02, Federal Reserve Bank of Kansas City.
  96. Patricia M. Danzon & Eric L. Keuffel, 2013. "Regulation of the Pharmaceutical-Biotechnology Industry," NBER Chapters, in: Economic Regulation and Its Reform: What Have We Learned? National Bureau of Economic Research, Inc.
  97. Lee Branstetter & Kwon Hyeog Ug, 2004. "The Restructuring Of Japanese Research And Development: The Increasing Impact Of Science On Japanese R&D," Discussion papers 04021, Research Institute of Economy, Trade and Industry (RIETI).