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Improving the Availability of Unrelated Stem Cell Donors: Evidence from a Major Donor Registry

Author

Listed:
  • Haylock, Michael

    (University of Tübingen)

  • Kampkötter, Patrick

    (University of Tübingen)

  • Macis, Mario

    (The Johns Hopkins Carey Business School)

  • Sauter, Jürgen

    (DKMS gGmbh Tübingen)

  • Seitz, Susanne

    (DKMS gGmbh Tübingen)

  • Slonim, Robert

    (University of Sydney)

  • Wiesen, Daniel

    (University of Cologne)

  • Schmidt, Alexander H.

    (DKMS gGmbh Tübingen)

Abstract

The unavailability of potential stem cell donors poses a critical challenge for donor registries worldwide. This study investigates the impact of initiatives of a stem cell donor registry to enhance donors' availability for confirmatory typing. Initiatives ask donors to provide a sample for genetic analysis and/or information on their temporal unavailability. We analyzed 91,479 confirmatory typing requests from DKMS Germany, a large stem cell donor registry, exploiting a quasi-random initiative assignment based on observable characteristics. We find that, first, invitation to the initiatives increases donors' availability. Intention-to-treat estimates yield effects ranging from 2.5 to 3.2 percentage points, and local average treatment effects estimates range from 3.8 to 8.2 percentage points ( baseline: 77.1%). Second, the difference in availability between participants and non-participants is over 10 percentage points. The initiatives yield a direct positive effect on donor availability and a selection effect through which participation signals a higher commitment.

Suggested Citation

  • Haylock, Michael & Kampkötter, Patrick & Macis, Mario & Sauter, Jürgen & Seitz, Susanne & Slonim, Robert & Wiesen, Daniel & Schmidt, Alexander H., 2022. "Improving the Availability of Unrelated Stem Cell Donors: Evidence from a Major Donor Registry," IZA Discussion Papers 15096, Institute of Labor Economics (IZA).
    • Handle: RePEc:iza:izadps:dp15096
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    References listed on IDEAS

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    More about this item

    Keywords

    unrelated stem cell donation; donor availability; registry initiatives; sorting; intention-to-treat; local average treatment effects;
    All these keywords.

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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