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Improving the Availability of Unrelated Stem Cell Donors: Evidence from a Major Donor Registry

Author

Listed:
  • Michael Haylock
  • Patrick Kampkötter
  • Mario Macis
  • Jürgen Sauter
  • Susanne Seitz
  • Robert Slonim
  • Daniel Wiesen
  • Alexander H. Schmidt

Abstract

The unavailability of potential stem cell donors poses a critical challenge for donor registries worldwide. This study investigates the impact of initiatives of a stem cell donor registry to enhance donors' availability for confirmatory typing. Initiatives ask donors to provide a sample for genetic analysis and/or information on their temporal unavailability. We analyzed 91,479 confirmatory typing requests from DKMS Germany, a large stem cell donor registry, exploiting a quasi-random initiative assignment based on observable characteristics. We find that, first, invitation to the initiatives increases donors' availability. Intention-to-treat estimates yield effects ranging from 2.5 to 3.2 percentage points, and local average treatment effects estimates range from 3.8 to 8.2 percentage points (baseline: 77.1%). Second, the difference in availability between participants and non-participants is over 10 percentage points. The initiatives yield a direct positive effect on donor availability and a selection effect through which participation signals a higher commitment.

Suggested Citation

  • Michael Haylock & Patrick Kampkötter & Mario Macis & Jürgen Sauter & Susanne Seitz & Robert Slonim & Daniel Wiesen & Alexander H. Schmidt, 2022. "Improving the Availability of Unrelated Stem Cell Donors: Evidence from a Major Donor Registry," NBER Working Papers 29857, National Bureau of Economic Research, Inc.
    • Handle: RePEc:nbr:nberwo:29857
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    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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