IDEAS home Printed from https://ideas.repec.org/a/eee/jhecon/v80y2021ics016762962100117x.html
   My bibliography  Save this article

Early life adversity, biological adaptation, and human capital: evidence from an interrupted malaria control program in Zambia

Author

Listed:
  • Fink, Günther
  • Venkataramani, Atheendar S.
  • Zanolini, Arianna

Abstract

Growing evidence from evolutionary biology demonstrates how early life shocks trigger physiological changes designed to be adaptive in challenging environments. We examine the implications of one type of physiological adaptation – immunity formation - for human capital accumulation. Using variation in early life malaria risk generated by an interrupted disease control program in Zambia, we show that exposure to infectious diseases during the first two years of life can reduce the harmful effects of malaria exposure on cognitive development during the preschool years. These findings suggest a non-linear and trajectory-dependent relationship between early life adversity and human capital formation.

Suggested Citation

  • Fink, Günther & Venkataramani, Atheendar S. & Zanolini, Arianna, 2021. "Early life adversity, biological adaptation, and human capital: evidence from an interrupted malaria control program in Zambia," Journal of Health Economics, Elsevier, vol. 80(C).
  • Handle: RePEc:eee:jhecon:v:80:y:2021:i:c:s016762962100117x
    DOI: 10.1016/j.jhealeco.2021.102532
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S016762962100117X
    Download Restriction: Full text for ScienceDirect subscribers only

    File URL: https://libkey.io/10.1016/j.jhealeco.2021.102532?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Douglas Almond & Bhashkar Mazumder, 2013. "Fetal Origins and Parental Responses," Annual Review of Economics, Annual Reviews, vol. 5(1), pages 37-56, May.
    2. Michael Kremer & Edward Miguel, 2007. "The Illusion of Sustainability," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 122(3), pages 1007-1065.
    3. Eric B. Schneider, 2017. "Children's growth in an adaptive framework: explaining the growth patterns of American slaves and other historical populations," Economic History Review, Economic History Society, vol. 70(1), pages 3-29, February.
    4. Nava Ashraf & Günther Fink & David N. Weil, 2014. "Evaluating the Effects of Large-Scale Health Interventions in Developing Countries: The Zambian Malaria Initiative," NBER Chapters, in: African Successes, Volume II: Human Capital, pages 13-57, National Bureau of Economic Research, Inc.
    5. Abhijit Banerjee & Esther Duflo & Gilles Postel-Vinay & Timothy M. Watts, 2007. "Long Run Health Impacts of Income Shocks: Wine and Phylloxera in 19th Century France," NBER Working Papers 12895, National Bureau of Economic Research, Inc.
    6. James Heckman & Flavio Cunha, 2007. "The Technology of Skill Formation," American Economic Review, American Economic Association, vol. 97(2), pages 31-47, May.
    7. Pedro Carneiro & Lucy Kraftman & Giacomo Mason & Lucie Moore & Imran Rasul & Molly Scott, 2021. "The Impacts of a Multifaceted Prenatal Intervention on Human Capital Accumulation in Early Life," American Economic Review, American Economic Association, vol. 111(8), pages 2506-2549, August.
    8. Sharon Maccini & Dean Yang, 2009. "Under the Weather: Health, Schooling, and Economic Consequences of Early-Life Rainfall," American Economic Review, American Economic Association, vol. 99(3), pages 1006-1026, June.
    9. Douglas Almond & Janet Currie & Valentina Duque, 2018. "Childhood Circumstances and Adult Outcomes: Act II," Journal of Economic Literature, American Economic Association, vol. 56(4), pages 1360-1446, December.
    10. Rucker C. Johnson & C. Kirabo Jackson, 2019. "Reducing Inequality through Dynamic Complementarity: Evidence from Head Start and Public School Spending," American Economic Journal: Economic Policy, American Economic Association, vol. 11(4), pages 310-349, November.
    11. Eric Maskin & Célestin Monga & Josselin Thuilliez & Jean-Claude Berthélemy, 2019. "The economics of malaria control in an age of declining aid," Nature Communications, Nature, vol. 10(1), pages 1-5, December.
    12. Orazio Attanasio & Sarah Cattan & Emla Fitzsimons & Costas Meghir & Marta Rubio-Codina, 2020. "Estimating the Production Function for Human Capital: Results from a Randomized Controlled Trial in Colombia," American Economic Review, American Economic Association, vol. 110(1), pages 48-85, January.
    13. Flavio Cunha & James J. Heckman & Susanne M. Schennach, 2010. "Estimating the Technology of Cognitive and Noncognitive Skill Formation," Econometrica, Econometric Society, vol. 78(3), pages 883-931, May.
    14. Maria Kuecken & Josselin Thuilliez & Marie-Anne Valfort, 2021. "Disease and Human Capital Accumulation: Evidence from the Roll Back Malaria Partnership in Africa," The Economic Journal, Royal Economic Society, vol. 131(637), pages 2171-2202.
    15. Josselin Thuilliez & Hippolyte d'Albis & Hamidou Niangaly & Ogobara Doumbo, 2017. "Malaria and Education: Evidence from Mali," Journal of African Economies, Centre for the Study of African Economies, vol. 26(4), pages 443-469.
    16. Daniel Bennett, 2012. "Does Clean Water Make You Dirty?: Water Supply and Sanitation in the Philippines," Journal of Human Resources, University of Wisconsin Press, vol. 47(1), pages 146-173.
    17. Dana Charles McCoy & Evan D Peet & Majid Ezzati & Goodarz Danaei & Maureen M Black & Christopher R Sudfeld & Wafaie Fawzi & Günther Fink, 2016. "Early Childhood Developmental Status in Low- and Middle-Income Countries: National, Regional, and Global Prevalence Estimates Using Predictive Modeling," PLOS Medicine, Public Library of Science, vol. 13(6), pages 1-18, June.
    18. Zhuan Pei & Jörn-Steffen Pischke & Hannes Schwandt, 2019. "Poorly Measured Confounders are More Useful on the Left than on the Right," Journal of Business & Economic Statistics, Taylor & Francis Journals, vol. 37(2), pages 205-216, April.
    19. Abhijit Banerjee & Esther Duflo & Gilles Postel-Vinay & Tim Watts, 2010. "Long-Run Health Impacts of Income Shocks: Wine and Phylloxera in Nineteenth-Century France," The Review of Economics and Statistics, MIT Press, vol. 92(4), pages 714-728, November.
    20. Venkataramani, Atheendar S., 2012. "Early life exposure to malaria and cognition in adulthood: Evidence from Mexico," Journal of Health Economics, Elsevier, vol. 31(5), pages 767-780.
    21. Edward Miguel & Michael Kremer, 2004. "Worms: Identifying Impacts on Education and Health in the Presence of Treatment Externalities," Econometrica, Econometric Society, vol. 72(1), pages 159-217, January.
    22. van den Berg, Gerard J. & Siflinger, Bettina M., 2018. "The Effects of Day Care on Health During Childhood: Evidence by Age," IZA Discussion Papers 11447, Institute of Labor Economics (IZA).
    23. Nicholas Wilson, 2015. "Can Disease-Specific Funding Harm Health? in the Shadow of HIV/AIDS Service Expansion," Demography, Springer;Population Association of America (PAA), vol. 52(5), pages 1671-1700, October.
    24. James J. Heckman, 2007. "The Economics, Technology and Neuroscience of Human Capability Formation," NBER Working Papers 13195, National Bureau of Economic Research, Inc.
    25. Maria Kuecken & Josselin Thuilliez & Marie-Anne Valfort, 2020. "Disease and Human Capital Accumulation: Evidence from the Roll Back Malaria Partnership in Africa," Université Paris1 Panthéon-Sorbonne (Post-Print and Working Papers) halshs-03057577, HAL.
    26. Hong, Sok Chul, 2007. "The Burden of Early Exposure to Malaria in the United States, 1850–1860: Malnutrition and Immune Disorders," The Journal of Economic History, Cambridge University Press, vol. 67(4), pages 1001-1035, December.
    27. Adrienne M. Lucas & Nicholas L. Wilson, 2013. "Adult Antiretroviral Therapy and Child Health: Evidence from Scale-Up in Zambia," American Economic Review, American Economic Association, vol. 103(3), pages 456-461, May.
    28. Simon Chang & Belton Fleisher & Seonghoon Kim & Shi-yung Liu, 2014. "Long-Term Health Effects of Malaria Exposure around Birth: Evidence from Colonial Taiwan," Economic Development and Cultural Change, University of Chicago Press, vol. 62(3), pages 519-536.
    29. Barofsky, Jeremy & Anekwe, Tobenna D. & Chase, Claire, 2015. "Malaria eradication and economic outcomes in sub-Saharan Africa: Evidence from Uganda," Journal of Health Economics, Elsevier, vol. 44(C), pages 118-136.
    30. Wei Fan & Catherine Porter, 2020. "Reinforcement or compensation? Parental responses to children’s revealed human capital levels," Journal of Population Economics, Springer;European Society for Population Economics, vol. 33(1), pages 233-270, January.
    31. Adrienne M. Lucas, 2013. "The Impact of Malaria Eradication on Fertility," Economic Development and Cultural Change, University of Chicago Press, vol. 61(3), pages 607-631.
    32. Natalie Bau & Martin Rotemberg & Manisha Shah & Bryce Steinberg, 2020. "Human Capital Investment in the Presence of Child Labor," NBER Working Papers 27241, National Bureau of Economic Research, Inc.
    33. Fink, Günther & Masiye, Felix, 2015. "Health and agricultural productivity: Evidence from Zambia," Journal of Health Economics, Elsevier, vol. 42(C), pages 151-164.
    34. Alan I. Barreca, 2010. "The Long-Term Economic Impact of In Utero and Postnatal Exposure to Malaria," Journal of Human Resources, University of Wisconsin Press, vol. 45(4), pages 865-892.
    35. Hoyt Bleakley, 2010. "Malaria Eradication in the Americas: A Retrospective Analysis of Childhood Exposure," American Economic Journal: Applied Economics, American Economic Association, vol. 2(2), pages 1-45, April.
    36. Junjian Yi & James J. Heckman & Junsen Zhang & Gabriella Conti, 2015. "Early Health Shocks, Intra†household Resource Allocation and Child Outcomes," Economic Journal, Royal Economic Society, vol. 125(588), pages 347-371, November.
    37. Anna Aizer & Flávio Cunha, 2012. "The Production of Human Capital: Endowments, Investments and Fertility," NBER Working Papers 18429, National Bureau of Economic Research, Inc.
    38. Hilary Hoynes & Diane Whitmore Schanzenbach & Douglas Almond, 2016. "Long-Run Impacts of Childhood Access to the Safety Net," American Economic Review, American Economic Association, vol. 106(4), pages 903-934, April.
    39. Orazio Attanasio & Costas Meghir & Emily Nix & Francesca Salvati, 2017. "Human Capital Growth and Poverty: Evidence from Ethiopia and Peru," Review of Economic Dynamics, Elsevier for the Society for Economic Dynamics, vol. 25, pages 234-259, April.
    40. Josselin Thuilliez & Hippolyte d'Albis & Hamidou Niangaly & Ogobara Doumbo, 2017. "Malaria and Education: Evidence from Mali," Journal of African Economies, Centre for the Study of African Economies (CSAE), vol. 26(4), pages 443-469.
    41. David Cutler & Winnie Fung & Michael Kremer & Monica Singhal & Tom Vogl, 2010. "Early-Life Malaria Exposure and Adult Outcomes: Evidence from Malaria Eradication in India," American Economic Journal: Applied Economics, American Economic Association, vol. 2(2), pages 72-94, April.
    42. Snaebjorn Gunnsteinsson & Achyuta Adhvaryu & Parul Christian & Alain Labrique & Jonathan Sugimoto & Abu Ahmed Shamim & Keith P. West Jr, 2019. "Protecting Infants from Natural Disasters: The Case of Vitamin A Supplementation and a Tornado in Bangladesh," NBER Working Papers 25969, National Bureau of Economic Research, Inc.
    43. Adrienne M. Lucas, 2010. "Malaria Eradication and Educational Attainment: Evidence from Paraguay and Sri Lanka," American Economic Journal: Applied Economics, American Economic Association, vol. 2(2), pages 46-71, April.
    44. Sudhanshu Handa & Amber Peterman & David Seidenfeld & Gelson Tembo, 2016. "Income Transfers and Maternal Health: Evidence from a National Randomized Social Cash Transfer Program in Zambia," Health Economics, John Wiley & Sons, Ltd., vol. 25(2), pages 225-236, February.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Chang, Simon & Kan, Kamhon, 2022. "Do Good Carefully: The Long-Term Effects of DDT Exposure in Early Childhood on Education and Employment," IZA Discussion Papers 15075, Institute of Labor Economics (IZA).
    2. Alexis Rulisa & Luuk van Kempen & Dirk-Jan Koch, 2022. "When Local Trade-Offs between SDGs Turn Out to Be Wealth-Dependent: Interaction between Expanding Rice Cultivation and Eradicating Malaria in Rwanda," Sustainability, MDPI, vol. 14(4), pages 1-24, February.
    3. Simon Chang & Kamhon Kan, 2023. "Do good carefully: The long‐term effects of low‐dose DDT exposure in early childhood on education, marriage and employment," Health Economics, John Wiley & Sons, Ltd., vol. 32(4), pages 807-821, April.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Duque, Valentina & Rosales-Rueda, Maria & Sanchez, Fabio, 2019. "How Do Early-Life Shocks Interact with Subsequent Human Capital Investments? Evidence from Administrative Data," Working Papers 2019-17, University of Sydney, School of Economics.
    2. Gabriella Conti, 2013. "The Developmental Origins of Health Inequality," Research on Economic Inequality, in: Health and Inequality, volume 21, pages 285-309, Emerald Group Publishing Limited.
    3. Lazuka, Volha, 2017. "Infant health and later-life labour market outcomes : Evidence from the introduction of sulfa antibiotics in Sweden," Lund Papers in Economic History 154, Lund University, Department of Economic History.
    4. Gensowski, Miriam & Nielsen, Torben Heien & Nielsen, Nete Munk & Rossin-Slater, Maya & Wüst, Miriam, 2019. "Childhood health shocks, comparative advantage, and long-term outcomes: Evidence from the last Danish polio epidemic," Journal of Health Economics, Elsevier, vol. 66(C), pages 27-36.
    5. Maria Kuecken & Josselin Thuilliez & Marie-Anne Valfort, 2013. "Large-scale health interventions and education: Evidence from Roll Back Malaria in Africa," Documents de travail du Centre d'Economie de la Sorbonne 13075r, Université Panthéon-Sorbonne (Paris 1), Centre d'Economie de la Sorbonne, revised Jun 2015.
    6. Tushar Bharati & Seungwoo Chin & Dawoon Jung, 2020. "Recovery from an Early-Life Shock through Improved Access to Schools," Economics Discussion / Working Papers 20-04, The University of Western Australia, Department of Economics.
    7. Pan, Yao & Singhal, Saurabh, 2019. "Agricultural extension, intra-household allocation and malaria," Journal of Development Economics, Elsevier, vol. 139(C), pages 157-170.
    8. Shoji, Masahiro, 2020. "Early-Life Circumstances and Adult Locus of Control: Evidence from 46 Developing Countries," MPRA Paper 99987, University Library of Munich, Germany.
    9. Cirera, Laia & Castelló, Judit Vall & Brew, Joe & Saúte, Francisco & Sicuri, Elisa, 2022. "The impact of a malaria elimination initiative on school outcomes: Evidence from Southern Mozambique," Economics & Human Biology, Elsevier, vol. 44(C).
    10. Richard Akresh & Sonia Bhalotra & Marinella Leone & Una Osili, 2023. "First- and Second-Generation Impacts of the Biafran War," Journal of Human Resources, University of Wisconsin Press, vol. 58(2), pages 488-531.
    11. Samantha Rawlings, 2012. "Gender, race, and heterogeneous scarring and selection effects of epidemic malaria on human capital," Economics Discussion Papers em-dp2012-01, Department of Economics, University of Reading.
    12. Bhalotra, Sonia R. & Venkataramani, Atheendar, 2011. "The Captain of the Men of Death and His Shadow: Long-Run Impacts of Early Life Pneumonia Exposure," IZA Discussion Papers 6041, Institute of Labor Economics (IZA).
    13. Berthelon, Matias & Kruger, Diana & Sanchez, Rafael, 2021. "Maternal stress during pregnancy and early childhood development," Economics & Human Biology, Elsevier, vol. 43(C).
    14. Hsiu‐Han Shih & Ming‐Jen Lin, 2018. "Long‐term impacts of early‐life exposure to malaria: Evidence from Taiwan's Eradication Campaign in the 1950s," Health Economics, John Wiley & Sons, Ltd., vol. 27(10), pages 1484-1512, October.
    15. Deng, Zichen & Lindeboom, Maarten, 2022. "A bit of salt, a trace of life: Gender norms and the impact of a salt iodization program on human capital formation of school aged children," Journal of Health Economics, Elsevier, vol. 83(C).
    16. Schwandt, Hannes, 2017. "The Lasting Legacy of Seasonal Influenza: In-utero Exposure and Labor Market Outcomes," DaCHE discussion papers 2017:5, University of Southern Denmark, Dache - Danish Centre for Health Economics.
    17. Jia Wu & Jiada Lin & Xiao Han, 2023. "Compensation for girls in early childhood and its long-run impact: family investment strategies under rainfall shocks," Journal of Population Economics, Springer;European Society for Population Economics, vol. 36(3), pages 1225-1268, July.
    18. Tafesse, W.;, 2018. "The effect of mandatory iodine fortification on cognitive test scores in rural India," Health, Econometrics and Data Group (HEDG) Working Papers 18/10, HEDG, c/o Department of Economics, University of York.
    19. Richard Akresh & Sonia Bhalotra & Marinella Leone & Una Osili, 2017. "Hunger Games: First and Second Generation Impacts of the Biafran War," HiCN Working Papers 254, Households in Conflict Network.
    20. Gunnsteinsson, Snaebjorn & Molina, Teresa & Adhvaryu, Achyuta & Christian, Parul & Labrique, Alain & Sugimoto, Jonathan & Shamim, Abu Ahmed & West, Keith P., 2022. "Protecting infants from natural disasters: The case of vitamin A supplementation and a tornado in Bangladesh," Journal of Development Economics, Elsevier, vol. 158(C).

    More about this item

    Keywords

    Human capital; Early childhood; Immunity; Biological responses; Cognition; Education; Malaria;
    All these keywords.

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General
    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • J13 - Labor and Demographic Economics - - Demographic Economics - - - Fertility; Family Planning; Child Care; Children; Youth
    • J24 - Labor and Demographic Economics - - Demand and Supply of Labor - - - Human Capital; Skills; Occupational Choice; Labor Productivity

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:jhecon:v:80:y:2021:i:c:s016762962100117x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/inca/505560 .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.