IDEAS home Printed from https://ideas.repec.org/a/spr/anresc/v46y2011i3p519-541.html
   My bibliography  Save this article

Regional knowledge production in nanomaterials: a spatial filtering approach

Author

Listed:
  • Christoph Grimpe
  • Roberto Patuelli

Abstract

Nanomaterials are seen as a key technology for the 21st Century, and much is expected of them in terms of innovation and economic growth. They could open the way to many radically new applications, which would form the basis of innovative products. In this context, it seems all the more important for regions to put their own innovation systems in place, and to ensure that they offer a suitable location for such activities in order to benefit from the expected growth. Many regions have already done so by establishing ‘science parks’ and ‘nanoclusters’. As nanomaterials are still in their infancy, both public research institutes and private businesses could play a vital role in the process. This paper investigates what conditions and configurations allow a regional innovation system to be competitive in a cutting-edge technology like nanomaterials. We analyse European Patent Office data at the German district level (NUTS-3) on applications for nanomaterial patents, in order to chart the effects of localised research and development (R&D) in the public and private sector. We estimate two negative binomial models in a knowledge production function framework and include a spatial filtering approach to adjust for spatial effects. Our results indicate that there is a significant positive effect of both public and private R&D on the production of nanomaterial patents. Moreover, we find a positive interaction between them which hints at the importance of their co-location for realising the full potential of an emerging technology like nanomaterials.
(This abstract was borrowed from another version of this item.)

Suggested Citation

  • Christoph Grimpe & Roberto Patuelli, 2011. "Regional knowledge production in nanomaterials: a spatial filtering approach," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 46(3), pages 519-541, June.
    • Handle: RePEc:spr:anresc:v:46:y:2011:i:3:p:519-541
    DOI: 10.1007/s00168-009-0355-y
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1007/s00168-009-0355-y
    Download Restriction: Access to full text is restricted to subscribers.
    File URL: https://libkey.io/10.1007/s00168-009-0355-y?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to look for a different version below or search for a different version of it.

    Other versions of this item:

    References listed on IDEAS

    as
    1. Martin Meyer, 2006. "Are Co-Active Researchers on Top of their Class? An Exploratory Comparison of Inventor-Authors with their Non-Inventing Peers in Nano-Science and Technology," SPRU Working Paper Series 144, SPRU - Science Policy Research Unit, University of Sussex Business School.
    2. Acs, Zoltan J & Audretsch, David B & Feldman, Maryann P, 1994. "R&D Spillovers and Recipient Firm Size," The Review of Economics and Statistics, MIT Press, vol. 76(2), pages 336-340, May.
    3. David B. Audretsch, 2003. "Innovation And Spatial Externalities," International Regional Science Review, , vol. 26(2), pages 167-174, April.
    4. Meyer, Martin, 2006. "Are patenting scientists the better scholars?: An exploratory comparison of inventor-authors with their non-inventing peers in nano-science and technology," Research Policy, Elsevier, vol. 35(10), pages 1646-1662, December.
    5. repec:fth:harver:1473 is not listed on IDEAS
    6. Martin, Ron, 1999. "The New 'Geographical Turn' in Economics: Some Critical Reflections," Cambridge Journal of Economics, Cambridge Political Economy Society, vol. 23(1), pages 65-91, January.
    7. Cooke, Philip & Gomez Uranga, Mikel & Etxebarria, Goio, 1997. "Regional innovation systems: Institutional and organisational dimensions," Research Policy, Elsevier, vol. 26(4-5), pages 475-491, December.
    8. Jan Youtie & Maurizio Iacopetta & Stuart Graham, 2008. "Assessing the nature of nanotechnology: can we uncover an emerging general purpose technology?," The Journal of Technology Transfer, Springer, vol. 33(3), pages 315-329, June.
    9. Yang, Chih-Hai & Motohashi, Kazuyuki & Chen, Jong-Rong, 2009. "Are new technology-based firms located on science parks really more innovative?: Evidence from Taiwan," Research Policy, Elsevier, vol. 38(1), pages 77-85, February.
    10. Luc Anselin & Attila Varga & Zoltan Acs, 2008. "Local Geographic Spillovers Between University Research and High Technology Innovations," Chapters, in: Entrepreneurship, Growth and Public Policy, chapter 9, pages 95-121, Edward Elgar Publishing.
    11. Feldman, Maryann P. & Audretsch, David B., 1999. "Innovation in cities:: Science-based diversity, specialization and localized competition," European Economic Review, Elsevier, vol. 43(2), pages 409-429, February.
    12. Jaffe, Adam B, 1989. "Real Effects of Academic Research," American Economic Review, American Economic Association, vol. 79(5), pages 957-970, December.
    13. Aghion, Philippe & Howitt, Peter, 1992. "A Model of Growth through Creative Destruction," Econometrica, Econometric Society, vol. 60(2), pages 323-351, March.
    14. Samuel Kortum & Josh Lerner, 2000. "Assessing the Contribution of Venture Capital to Innovation," RAND Journal of Economics, The RAND Corporation, vol. 31(4), pages 674-692, Winter.
    15. Mullahy, John, 1986. "Specification and testing of some modified count data models," Journal of Econometrics, Elsevier, vol. 33(3), pages 341-365, December.
    16. Zvi Griliches, 1984. "Market Value, R&D, and Patents," NBER Chapters, in: R&D, Patents, and Productivity, pages 249-252, National Bureau of Economic Research, Inc.
    17. Eric von Hippel, 1994. ""Sticky Information" and the Locus of Problem Solving: Implications for Innovation," Management Science, INFORMS, vol. 40(4), pages 429-439, April.
    18. Attila Varga, 2000. "Local Academic Knowledge Transfers and the Concentration of Economic Activity," Journal of Regional Science, Wiley Blackwell, vol. 40(2), pages 289-309, May.
    19. Zvi Griliches, 1998. "Issues in Assessing the Contribution of Research and Development to Productivity Growth," NBER Chapters, in: R&D and Productivity: The Econometric Evidence, pages 17-45, National Bureau of Economic Research, Inc.
    20. Cohen, Wesley M & Levinthal, Daniel A, 1989. "Innovation and Learning: The Two Faces of R&D," Economic Journal, Royal Economic Society, vol. 99(397), pages 569-596, September.
    21. Hulya Ulku, 2004. "R&D, Innovation, and Economic Growth: An Empirical Analysis," IMF Working Papers 2004/185, International Monetary Fund.
    22. K. J. Arrow, 1971. "The Economic Implications of Learning by Doing," Palgrave Macmillan Books, in: F. H. Hahn (ed.), Readings in the Theory of Growth, chapter 11, pages 131-149, Palgrave Macmillan.
    23. Harhoff, Dietmar & Scherer, Frederic M. & Vopel, Katrin, 2003. "Citations, family size, opposition and the value of patent rights," Research Policy, Elsevier, vol. 32(8), pages 1343-1363, September.
    24. Bronwyn H. Hall & Albert N. Link & John T. Scott, 2003. "Universities as Research Partners," The Review of Economics and Statistics, MIT Press, vol. 85(2), pages 485-491, May.
    25. Audretsch, David B. & Keilbach, Max, 2008. "Resolving the knowledge paradox: Knowledge-spillover entrepreneurship and economic growth," Research Policy, Elsevier, vol. 37(10), pages 1697-1705, December.
    26. M Tiefelsdorf & B Boots, 1995. "The Exact Distribution of Moran's I," Environment and Planning A, , vol. 27(6), pages 985-999, June.
    27. Zoltan J. Acs & David B. Audretsch & Maryann P. Feldman, 2008. "R&D Spillovers and Recipient Firm Size," Chapters, in: Entrepreneurship, Growth and Public Policy, chapter 8, pages 88-94, Edward Elgar Publishing.
    28. Zoltan J. Acs & Luc Anselin & Attila Varga, 2008. "Patents and Innovation Counts as Measures of Regional Production of New Knowledge," Chapters, in: Entrepreneurship, Growth and Public Policy, chapter 11, pages 135-151, Edward Elgar Publishing.
    29. Daniel A. Griffith, 2000. "A linear regression solution to the spatial autocorrelation problem," Journal of Geographical Systems, Springer, vol. 2(2), pages 141-156, July.
    30. Griliches, Zvi, 1998. "R&D and Productivity," National Bureau of Economic Research Books, University of Chicago Press, edition 1, number 9780226308869, December.
    31. Bozeman, Barry & Laredo, Philippe & Mangematin, Vincent, 2007. "Understanding the emergence and deployment of "nano" S&T," Research Policy, Elsevier, vol. 36(6), pages 807-812, July.
    32. Paul M. Romer, 1994. "The Origins of Endogenous Growth," Journal of Economic Perspectives, American Economic Association, vol. 8(1), pages 3-22, Winter.
    33. Barry Bozeman & Philippe Larédo & Vincent Mangematin, 2007. "Understanding the emergence and deployment of “nano” S&T," Post-Print hal-00424523, HAL.
    34. Hall, Bronwyn H & Griliches, Zvi & Hausman, Jerry A, 1986. "Patents and R and D: Is There a Lag?," International Economic Review, Department of Economics, University of Pennsylvania and Osaka University Institute of Social and Economic Research Association, vol. 27(2), pages 265-283, June.
    35. Olivier Parent & James P. LeSage, 2008. "Using the variance structure of the conditional autoregressive spatial specification to model knowledge spillovers," Journal of Applied Econometrics, John Wiley & Sons, Ltd., vol. 23(2), pages 235-256.
    36. Pavitt, Keith, 1984. "Sectoral patterns of technical change: Towards a taxonomy and a theory," Research Policy, Elsevier, vol. 13(6), pages 343-373, December.
    37. Zvi Griliches, 1998. "Patent Statistics as Economic Indicators: A Survey," NBER Chapters, in: R&D and Productivity: The Econometric Evidence, pages 287-343, National Bureau of Economic Research, Inc.
    38. Audretsch, David B & Feldman, Maryann P, 1996. "R&D Spillovers and the Geography of Innovation and Production," American Economic Review, American Economic Association, vol. 86(3), pages 630-640, June.
    39. Zoltan J. Acs & David B. Audretsch & Maryann P. Feldman, 2008. "Real Effects of Academic Research: Comment," Chapters, in: Entrepreneurship, Growth and Public Policy, chapter 7, pages 83-87, Edward Elgar Publishing.
    40. M Tiefelsdorf & D A Griffith & B Boots, 1999. "A Variance-Stabilizing Coding Scheme for Spatial Link Matrices," Environment and Planning A, , vol. 31(1), pages 165-180, January.
    41. Michael Tiefelsdorf & Daniel A Griffith, 2007. "Semiparametric Filtering of Spatial Autocorrelation: The Eigenvector Approach," Environment and Planning A, , vol. 39(5), pages 1193-1221, May.
    42. Furman, Jeffrey L. & Porter, Michael E. & Stern, Scott, 2002. "The determinants of national innovative capacity," Research Policy, Elsevier, vol. 31(6), pages 899-933, August.
    43. Arthur Getis, 1995. "Spatial Filtering in a Regression Framework: Examples Using Data on Urban Crime, Regional Inequality, and Government Expenditures," Advances in Spatial Science, in: Luc Anselin & Raymond J. G. M. Florax (ed.), New Directions in Spatial Econometrics, chapter 8, pages 172-185, Springer.
    44. Jones, Charles I, 1995. "R&D-Based Models of Economic Growth," Journal of Political Economy, University of Chicago Press, vol. 103(4), pages 759-784, August.
    45. Joachim Schummer, 2004. "Multidisciplinarity, interdisciplinarity, and patterns of research collaboration in nanoscience and nanotechnology," Scientometrics, Springer;Akadémiai Kiadó, vol. 59(3), pages 425-465, March.
    46. Cameron, A. Colin & Trivedi, Pravin K., 1990. "Regression-based tests for overdispersion in the Poisson model," Journal of Econometrics, Elsevier, vol. 46(3), pages 347-364, December.
    47. Daniel A. Griffith, 2003. "Spatial Autocorrelation and Spatial Filtering," Advances in Spatial Science, Springer, number 978-3-540-24806-4, Fall.
    48. Howells, Jeremy, 2005. "Innovation and regional economic development: A matter of perspective?," Research Policy, Elsevier, vol. 34(8), pages 1220-1234, October.
    49. Laranja, Manuel & Uyarra, Elvira & Flanagan, Kieron, 2008. "Policies for science, technology and innovation: Translating rationales into regional policies in a multi-level setting," Research Policy, Elsevier, vol. 37(5), pages 823-835, June.
    50. Almeida, Paul & Kogut, Bruce, 1997. "The Exploration of Technological Diversity and the Geographic Localization of Innovation," Small Business Economics, Springer, vol. 9(1), pages 21-31, February.
    51. R. Paci & S. Usai, 2000. "Externalities, knowledge spillovers and the spatial distribution of innovation," Working Paper CRENoS 200002, Centre for North South Economic Research, University of Cagliari and Sassari, Sardinia.
    52. Todtling, Franz & Trippl, Michaela, 2005. "One size fits all?: Towards a differentiated regional innovation policy approach," Research Policy, Elsevier, vol. 34(8), pages 1203-1219, October.
    53. Angela Hullmann & Martin Meyer, 2003. "Publications and patents in nanotechnology," Scientometrics, Springer;Akadémiai Kiadó, vol. 58(3), pages 507-527, November.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Gianni Guastella & Frank G. van Oort, 2015. "Regional Heterogeneity and Interregional Research Spillovers in European Innovation: Modelling and Policy Implications," Regional Studies, Taylor & Francis Journals, vol. 49(11), pages 1772-1787, November.
    2. repec:zbw:rwirep:0311 is not listed on IDEAS
    3. Dirk Engel & Timo Mitze & Roberto Patuelli & Janina Reinkowski, 2013. "Does Cluster Policy Trigger R&D Activity? Evidence from German Biotech Contests," European Planning Studies, Taylor & Francis Journals, vol. 21(11), pages 1735-1759, November.
    4. Timo Mitze & Falk Strotebeck, 2012. "What Drives Regional Cooperative Behavior in German Biotechnology? Embedding Social Network Analysis in a Regression Framework," ERSA conference papers ersa12p629, European Regional Science Association.
    5. Christoph Grimpe & Katrin Hussinger & Wolfgang Sofka, 2023. "Reaching beyond the acquirer-Target Dyad in M&A – Linkages to External knowledge sources and target firm valuation," DEM Discussion Paper Series 23-01, Department of Economics at the University of Luxembourg.
    6. Roberto Patuelli & Andrea Vaona & Christoph Grimpe, 2010. "The German East‐West Divide In Knowledge Production: An Application To Nanomaterial Patenting," Tijdschrift voor Economische en Sociale Geografie, Royal Dutch Geographical Society KNAG, vol. 101(5), pages 568-582, December.
    7. repec:elg:eechap:14395_24 is not listed on IDEAS
    8. Joana Mendonça & Christoph Grimpe, 2016. "Skills and regional entrepreneurship capital formation: a comparison between Germany and Portugal," The Journal of Technology Transfer, Springer, vol. 41(6), pages 1440-1456, December.
    9. Yongwan Chun & Daniel A. Griffith & Monghyeon Lee & Parmanand Sinha, 2016. "Eigenvector selection with stepwise regression techniques to construct eigenvector spatial filters," Journal of Geographical Systems, Springer, vol. 18(1), pages 67-85, January.
    10. Mitze, Timo & Strotebeck, Falk, 2019. "Determining factors of interregional research collaboration in Germany's biotech network: Capacity, proximity, policy?," Technovation, Elsevier, vol. 80, pages 40-53.
    11. Janina Reinkowski, 2014. "Empirical Essays in the Economics of Ageing and the Economics of Innovation," ifo Beiträge zur Wirtschaftsforschung, ifo Institute - Leibniz Institute for Economic Research at the University of Munich, number 53.
    12. Daisuke Murakami & Daniel Griffith, 2015. "Random effects specifications in eigenvector spatial filtering: a simulation study," Journal of Geographical Systems, Springer, vol. 17(4), pages 311-331, October.
    13. Mitze, Timo & Strotebeck, Falk, 2017. "Modeling interregional research collaborations in German biotechnology using industry directory data: A quantitative social network analysis," MPRA Paper 83392, University Library of Munich, Germany.
    14. Sylvain Barde & Rowan Cherodian & Guy Tchuente, 2023. "Moran's I Lasso for models with spatially correlated data," Papers 2310.02773, arXiv.org.
    15. Dirk Engel & Timo Mitze & Roberto Patuelli & Janina Reinkowski, 2013. "Does Cluster Policy Trigger R&D Activity? Evidence from German Biotech Contests," European Planning Studies, Taylor & Francis Journals, vol. 21(11), pages 1735-1759, November.
    16. James LeSage & Carlos Llano-Verduras, 2014. "Forecasting spatially dependent origin and destination commodity flows," Empirical Economics, Springer, vol. 47(4), pages 1543-1562, December.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Roberto Patuelli & Andrea Vaona & Christoph Grimpe, 2010. "The German East‐West Divide In Knowledge Production: An Application To Nanomaterial Patenting," Tijdschrift voor Economische en Sociale Geografie, Royal Dutch Geographical Society KNAG, vol. 101(5), pages 568-582, December.
    2. repec:rim:rimwps:29-08 is not listed on IDEAS
    3. Zoltán J. Ács & Pontus Braunerhjelm & David B. Audretsch & Bo Carlsson, 2015. "The knowledge spillover theory of entrepreneurship," Chapters, in: Global Entrepreneurship, Institutions and Incentives, chapter 7, pages 129-144, Edward Elgar Publishing.
    4. Erik E. Lehmann & Matthias Menter & Katharine Wirsching, 2022. "University spillovers, absorptive capacities, and firm performance," Eurasian Business Review, Springer;Eurasia Business and Economics Society, vol. 12(1), pages 125-150, March.
    5. Miguélez, Ernest & Moreno, Rosina, 2015. "Knowledge flows and the absorptive capacity of regions," Research Policy, Elsevier, vol. 44(4), pages 833-848.
    6. Dongwoo Kang & Sandy Dall’erba, 2016. "Exploring the spatially varying innovation capacity of the US counties in the framework of Griliches’ knowledge production function: a mixed GWR approach," Journal of Geographical Systems, Springer, vol. 18(2), pages 125-157, April.
    7. Nobuya Fukugawa, 2013. "University spillovers into small technology-based firms: channel, mechanism, and geography," The Journal of Technology Transfer, Springer, vol. 38(4), pages 415-431, August.
    8. Castellacci, Fulvio, 2008. "Innovation and the competitiveness of industries: comparing the mainstream and the evolutionary approaches," MPRA Paper 27523, University Library of Munich, Germany.
    9. Ernest Miguélez & Rosina Moreno, 2013. "“Mobility, networks and innovation: The role of regions’ absorptive capacity”," IREA Working Papers 201316, University of Barcelona, Research Institute of Applied Economics, revised Oct 2013.
    10. Rakas, Marija & Hain, Daniel S., 2019. "The state of innovation system research: What happens beneath the surface?," Research Policy, Elsevier, vol. 48(9), pages 1-1.
    11. Cabrer-Borras, Bernardi & Serrano-Domingo, Guadalupe, 2007. "Innovation and R&D spillover effects in Spanish regions: A spatial approach," Research Policy, Elsevier, vol. 36(9), pages 1357-1371, November.
    12. Andrés Rodríguez-Pose & Marco Di Cataldo, 2015. "Quality of government and innovative performance in the regions of Europe," Journal of Economic Geography, Oxford University Press, vol. 15(4), pages 673-706.
    13. Thomas Doring & Jan Schnellenbach, 2006. "What do we know about geographical knowledge spillovers and regional growth?: A survey of the literature," Regional Studies, Taylor & Francis Journals, vol. 40(3), pages 375-395.
    14. Kleoniki Kalapouti & Nikos Varsakelis, 2015. "Intra and inter: regional knowledge spillovers in European Union," The Journal of Technology Transfer, Springer, vol. 40(5), pages 760-781, October.
    15. Kleoniki Kalapouti & Konstantinos Petridis & Chrisovalantis Malesios & Prasanta Kumar Dey, 2020. "Measuring efficiency of innovation using combined Data Envelopment Analysis and Structural Equation Modeling: empirical study in EU regions," Annals of Operations Research, Springer, vol. 294(1), pages 297-320, November.
    16. Rui Baptista & Joana Mendonça, 2010. "Proximity to knowledge sources and the location of knowledge-based start-ups," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 45(1), pages 5-29, August.
    17. Rosina Moreno & Ernest Miguélez, 2012. "A Relational Approach To The Geography Of Innovation: A Typology Of Regions," Journal of Economic Surveys, Wiley Blackwell, vol. 26(3), pages 492-516, July.
    18. Ernest Miguélez & Rosina Moreno, 2013. "Do Labour Mobility and Technological Collaborations Foster Geographical Knowledge Diffusion? The Case of European Regions," Growth and Change, Wiley Blackwell, vol. 44(2), pages 321-354, June.
    19. Nola Hewitt-Dundas, 2013. "The role of proximity in university-business cooperation for innovation," The Journal of Technology Transfer, Springer, vol. 38(2), pages 93-115, April.
    20. Riccardo Crescenzi & Andrés Rodríguez-Pose, 2013. "R&D, Socio-Economic Conditions, and Regional Innovation in the U.S," Growth and Change, Wiley Blackwell, vol. 44(2), pages 287-320, June.
    21. Conte, Andrea & Vivarelli, Marco, 2005. "One or Many Knowledge Production Functions? Mapping Innovative Activity Using Microdata," IZA Discussion Papers 1878, Institute of Labor Economics (IZA).

    More about this item

    Keywords

    C21; L60; O32; R11; R12;
    All these keywords.

    JEL classification:

    • L60 - Industrial Organization - - Industry Studies: Manufacturing - - - General
    • O32 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Management of Technological Innovation and R&D

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:anresc:v:46:y:2011:i:3:p:519-541. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.