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The nanotech versus the biotech revolution: Sources of productivity in incumbent firm research

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  • Rothaermel, Frank T.
  • Thursby, Marie

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  • Rothaermel, Frank T. & Thursby, Marie, 2007. "The nanotech versus the biotech revolution: Sources of productivity in incumbent firm research," Research Policy, Elsevier, vol. 36(6), pages 832-849, July.
  • Handle: RePEc:eee:respol:v:36:y:2007:i:6:p:832-849
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    1. Rebecca Henderson & Iain Cockburn, 1996. "Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery," RAND Journal of Economics, The RAND Corporation, vol. 27(1), pages 32-59, Spring.
    2. Holmstrom, Bengt, 1989. "Agency costs and innovation," Journal of Economic Behavior & Organization, Elsevier, vol. 12(3), pages 305-327, December.
    3. Andrea Ichino & Giovanni Maggi, 2000. "Work Environment and Individual Background: Explaining Regional Shirking Differentials in a Large Italian Firm," The Quarterly Journal of Economics, Oxford University Press, vol. 115(3), pages 1057-1090.
    4. Galambos, Louis & Sturchio, Jeffrey L., 1998. "Pharmaceutical Firms and the Transition to Biotechnology: A Study in Strategic Innovation," Business History Review, Cambridge University Press, vol. 72(02), pages 250-278, June.
    5. Hall, B. & Jaffe, A. & Trajtenberg, M., 2001. "The NBER Patent Citations Data File: Lessons, Insights and Methodological Tools," Papers 2001-29, Tel Aviv.
    6. Rothaermel, Frank T. & Thursby, Marie, 2005. "University-incubator firm knowledge flows: assessing their impact on incubator firm performance," Research Policy, Elsevier, vol. 34(3), pages 305-320, April.
    7. Corolleur, Catherine D. F. & Carrere, M. & Mangematin, V., 2004. "Turning scientific and technological human capital into economic capital: the experience of biotech start-ups in France," Research Policy, Elsevier, vol. 33(4), pages 631-642, May.
    8. Hagedoorn, John & Cloodt, Myriam, 2003. "Measuring innovative performance: is there an advantage in using multiple indicators?," Research Policy, Elsevier, vol. 32(8), pages 1365-1379, September.
    9. Hagedoorn, John, 2002. "Inter-firm R&D partnerships: an overview of major trends and patterns since 1960," Research Policy, Elsevier, vol. 31(4), pages 477-492, May.
    10. Joshua S. Gans & David H. Hsu & Scott Stern, 2002. "When Does Start-Up Innovation Spur the Gale of Creative Destruction?," RAND Journal of Economics, The RAND Corporation, vol. 33(4), pages 571-586, Winter.
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    12. Bozeman, Barry & Mangematin, Vincent, 2004. "Editor's introduction: building and deploying scientific and technical human capital," Research Policy, Elsevier, vol. 33(4), pages 565-568, May.
    13. Holmström, Bengt, 1989. "Agency Costs and Innovation," Working Paper Series 214, Research Institute of Industrial Economics.
    14. Rothaermel, Frank T., 2001. "Complementary assets, strategic alliances, and the incumbent's advantage: an empirical study of industry and firm effects in the biopharmaceutical industry," Research Policy, Elsevier, vol. 30(8), pages 1235-1251, October.
    15. Hausman, Jerry & Hall, Bronwyn H & Griliches, Zvi, 1984. "Econometric Models for Count Data with an Application to the Patents-R&D Relationship," Econometrica, Econometric Society, vol. 52(4), pages 909-938, July.
    16. Robert Jacobson, 1990. "Unobservable Effects and Business Performance," Marketing Science, INFORMS, vol. 9(1), pages 74-85.
    17. Gourieroux, Christian & Monfort, Alain & Trognon, Alain, 1984. "Pseudo Maximum Likelihood Methods: Applications to Poisson Models," Econometrica, Econometric Society, vol. 52(3), pages 701-720, May.
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    19. Rothaermel, Frank T. & Thursby, Marie, 2005. "Incubator firm failure or graduation?: The role of university linkages," Research Policy, Elsevier, vol. 34(7), pages 1076-1090, September.
    20. Thursby, Jerry G & Jensen, Richard & Thursby, Marie C, 2001. "Objectives, Characteristics and Outcomes of University Licensing: A Survey of Major U.S. Universities," The Journal of Technology Transfer, Springer, vol. 26(1-2), pages 59-72, January.
    21. Cameron, A Colin & Trivedi, Pravin K, 1986. "Econometric Models Based on Count Data: Comparisons and Applications of Some Estimators and Tests," Journal of Applied Econometrics, John Wiley & Sons, Ltd., vol. 1(1), pages 29-53, January.
    22. Vogelsang, Timothy J., 1997. "Wald-Type Tests for Detecting Breaks in the Trend Function of a Dynamic Time Series," Econometric Theory, Cambridge University Press, vol. 13(06), pages 818-848, December.
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    24. Adams, James D, 1990. "Fundamental Stocks of Knowledge and Productivity Growth," Journal of Political Economy, University of Chicago Press, vol. 98(4), pages 673-702, August.
    25. Acs, Zoltan J & Audretsch, David B, 1989. "Patents as a Measure of Innovative Activity," Kyklos, Wiley Blackwell, vol. 42(2), pages 171-180.
    26. Zucker, Lynne G & Darby, Michael R & Brewer, Marilynn B, 1998. "Intellectual Human Capital and the Birth of U.S. Biotechnology Enterprises," American Economic Review, American Economic Association, vol. 88(1), pages 290-306, March.
    27. Audretsch, David B & Stephan, Paula E, 1996. "Company-Scientist Locational Links: The Case of Biotechnology," American Economic Review, American Economic Association, vol. 86(3), pages 641-652, June.
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    Cited by:

    1. Catherine Beaudry, 2011. "Collaboration and contracting out versus funding and support Impact on the propensity to patent of Canadian biotechnology firms 1999-2005," CIRANO Working Papers 2011s-62, CIRANO.
    2. Maj Andersen, 2011. "Silent innovation: corporate strategizing in early nanotechnology evolution," The Journal of Technology Transfer, Springer, vol. 36(6), pages 680-696, December.
    3. Can Huang & Ad Notten & Nico Rasters, 2011. "Nanoscience and technology publications and patents: a review of social science studies and search strategies," The Journal of Technology Transfer, Springer, vol. 36(2), pages 145-172, April.
    4. Andrea Fernández-Ribas & Philip Shapira, 2009. "Technological diversity, scientific excellence and the location of inventive activities abroad: the case of nanotechnology," The Journal of Technology Transfer, Springer, vol. 34(3), pages 286-303, June.
    5. Vanhaverbeke, Wim & Li, Ying & Van de Vrande, Vareska, 2009. "The dual role of external corporate venturing in technological exploration," MPRA Paper 26488, University Library of Munich, Germany, revised 2010.
    6. Philip Shapira & Jan Youtie & Luciano Kay, 2011. "National innovation systems and the globalization of nanotechnology innovation," The Journal of Technology Transfer, Springer, vol. 36(6), pages 587-604, December.
    7. Munari, Federico & Toschi, Laura, 2014. "Running ahead in the nanotechnology gold rush. Strategic patenting in emerging technologies," Technological Forecasting and Social Change, Elsevier, vol. 83(C), pages 194-207.
    8. Antonio Messeni Petruzzelli & Daniele Rotolo & Vito Albino, 2014. "Determinants of Patent Citations in Biotechnology: An Analysis of Patent Influence Across the Industrial and Organizational Boundaries," SPRU Working Paper Series 2014-05, SPRU - Science and Technology Policy Research, University of Sussex.
    9. Fiedler, Marina & Welpe, Isabell M., 2010. "Antecedents of cooperative commercialisation strategies of nanotechnology firms," Research Policy, Elsevier, vol. 39(3), pages 400-410, April.
    10. Jerry Thursby & Marie Thursby, 2011. "University-industry linkages in nanotechnology and biotechnology: evidence on collaborative patterns for new methods of inventing," The Journal of Technology Transfer, Springer, vol. 36(6), pages 605-623, December.
    11. Nikulainen, Tuomo & Kulvik, Martti, 2009. "How General Are General Purpose Technologies? Evidence from nano-, bio- and ICT-technologies in Finland," Discussion Papers 1208, The Research Institute of the Finnish Economy.
    12. repec:eee:jbrese:v:86:y:2018:i:c:p:190-201 is not listed on IDEAS
    13. Hohberger, Jan, 2016. "Diffusion of science-based inventions," Technological Forecasting and Social Change, Elsevier, vol. 104(C), pages 66-77.
    14. Corine Genet & Khalid Errabi & Caroline Gauthier, 2012. "Which Model of Technology Transfer for Nanotechnology? A Comparison with Biotech and Microelectronics," Grenoble Ecole de Management (Post-Print) hal-00749152, HAL.
    15. Elisa Alvarez-Garrido & Gary Dushnitsky, 2016. "Are entrepreneurial venture's innovation rates sensitive to investor complementary assets? Comparing biotech ventures backed by corporate and independent VCs," Strategic Management Journal, Wiley Blackwell, vol. 37(5), pages 819-834, May.
    16. Alessandra Colombelli & Jackie Krafft & Francesco Quatraro, 2012. "The emergence of new technology-based sectors at the regional level: a proximity-based analysis of nanotechnology," Papers in Evolutionary Economic Geography (PEEG) 1211, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Jun 2012.
    17. Colombelli, Alessandra & Krafft, Jackie & Quatraro, Francesco, 2014. "The emergence of new technology-based sectors in European regions: A proximity-based analysis of nanotechnology," Research Policy, Elsevier, vol. 43(10), pages 1681-1696.
    18. Jerald Hage & Jonathon Mote & Gretchen Jordan, 2013. "Ideas, innovations, and networks: a new policy model based on the evolution of knowledge," Policy Sciences, Springer;Society of Policy Sciences, vol. 46(2), pages 199-216, June.
    19. Sarah Kaplan & Keyvan Vakili, 2015. "The double-edged sword of recombination in breakthrough innovation," Strategic Management Journal, Wiley Blackwell, vol. 36(10), pages 1435-1457, October.
    20. Vincent Mangematin & Khalid Errabi & Caroline Gauthier, 2011. "Large players in the nanogame: dedicated nanotech subsidiaries or distributed nanotech capabilities?," The Journal of Technology Transfer, Springer, vol. 36(6), pages 640-664, December.
    21. Mario Cimoli & Gabriel Porcile, 2009. "Sources of learning paths and technological capabilities: an introductory roadmap of development processes," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 18(7), pages 675-694.
    22. Nikulainen, Tuomo, 2007. "Identifying Nanotechnological Linkages in the Finnish Economy - An Explorative Study," Discussion Papers 1101, The Research Institute of the Finnish Economy.

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