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Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery

  • Rebecca Henderson
  • Iain Cockburn

We examine the relationship between firm size and research productivity in the pharmaceutical industry. Using detailed internal firm data, we find that larger research efforts are more productive, not only because they enjoy economies of scale, but also because they realize economies of scope by sustaining diverse portfolios of research projects that capture internal and external knowledge spillovers. In pharmaceuticals, economies of scope in research are important in shaping the boundaries of the firm, and it may be worth tolerating the static efficiency loss attributable to the market power of large firms in exchange for their superior innovative performance.

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Article provided by The RAND Corporation in its journal RAND Journal of Economics.

Volume (Year): 27 (1996)
Issue (Month): 1 (Spring)
Pages: 32-59

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Handle: RePEc:rje:randje:v:27:y:1996:i:spring:p:32-59
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