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Smoking and body weight: Evidence using genetic instruments

Author

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  • Wehby, George L.
  • Murray, Jeffrey C.
  • Wilcox, Allen
  • Lie, Rolv T.

Abstract

Several studies have evaluated whether the high and rising obesity rates over the past three decades may be due to the declining smoking rates. There is mixed evidence across studies – some find negative smoking effects and positive cigarette cost effects on body weight, while others find opposite effects. This study applies a unique approach to identify the smoking effects on body weight and to evaluate the heterogeneity in these effects across the body mass index (BMI) distribution by utilizing genetic instruments for smoking. Using a data sample of 1057 mothers from Norway, the study finds heterogeneous effects of cigarette smoking on BMI – smoking increases BMI at low/moderate BMI levels and decreases BMI at high BMI levels. The study highlights the potential advantages and challenges of employing genetic instrumental variables to identify behavior effects including the importance of qualifying the instruments and the need for large samples.

Suggested Citation

  • Wehby, George L. & Murray, Jeffrey C. & Wilcox, Allen & Lie, Rolv T., 2012. "Smoking and body weight: Evidence using genetic instruments," Economics & Human Biology, Elsevier, vol. 10(2), pages 113-126.
    • Handle: RePEc:eee:ehbiol:v:10:y:2012:i:2:p:113-126
    DOI: 10.1016/j.ehb.2011.09.002
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    References listed on IDEAS

    as
    1. Koenker, Roger W & Bassett, Gilbert, Jr, 1978. "Regression Quantiles," Econometrica, Econometric Society, vol. 46(1), pages 33-50, January.
    2. Bhattacharya, Jay & Bundorf, M. Kate, 2009. "The incidence of the healthcare costs of obesity," Journal of Health Economics, Elsevier, vol. 28(3), pages 649-658, May.
    3. Charles L. Baum & William F. Ford, 2004. "The wage effects of obesity: a longitudinal study," Health Economics, John Wiley & Sons, Ltd., vol. 13(9), pages 885-899.
    4. Edward C. Norton & Euna Han, 2008. "Genetic information, obesity, and labor market outcomes," Health Economics, John Wiley & Sons, Ltd., vol. 17(9), pages 1089-1104.
    5. Smith Trenton G. & Stoddard Christiana & Barnes Michael G, 2009. "Why the Poor Get Fat: Weight Gain and Economic Insecurity," Forum for Health Economics & Policy, De Gruyter, vol. 12(2), pages 1-31, June.
    6. Jason M. Fletcher, 2011. "The promise and pitfalls of combining genetic and economic research," Health Economics, John Wiley & Sons, Ltd., vol. 20(8), pages 889-892, August.
    7. Stephanie von Hinke Kessler Scholder & George Davey Smith & Debbie A. Lawlor & Carol Propper & Frank Windmeijer, 2011. "Mendelian randomization: the use of genes in instrumental variable analyses," Health Economics, John Wiley & Sons, Ltd., vol. 20(8), pages 893-896, August.
    8. Chernozhukov, Victor & Hansen, Christian, 2008. "The reduced form: A simple approach to inference with weak instruments," Economics Letters, Elsevier, vol. 100(1), pages 68-71, July.
    9. Rees, Daniel I. & Sabia, Joseph J., 2010. "Body weight and smoking initiation: Evidence from Add Health," Journal of Health Economics, Elsevier, vol. 29(5), pages 774-777, September.
    10. Victor Chernozhukov & Christian Hansen, 2005. "An IV Model of Quantile Treatment Effects," Econometrica, Econometric Society, vol. 73(1), pages 245-261, January.
    11. Cawley, John & Markowitz, Sara & Tauras, John, 2004. "Lighting up and slimming down: the effects of body weight and cigarette prices on adolescent smoking initiation," Journal of Health Economics, Elsevier, vol. 23(2), pages 293-311, March.
    12. John Cawley & Euna Han & Edward C. Norton, 2011. "The validity of genes related to neurotransmitters as instrumental variables," Health Economics, John Wiley & Sons, Ltd., vol. 20(8), pages 884-888, August.
    13. Terza, Joseph V. & Basu, Anirban & Rathouz, Paul J., 2008. "Two-stage residual inclusion estimation: Addressing endogeneity in health econometric modeling," Journal of Health Economics, Elsevier, vol. 27(3), pages 531-543, May.
    14. Fang, Hai & Ali, Mir M. & Rizzo, John A., 2009. "Does smoking affect body weight and obesity in China?," Economics & Human Biology, Elsevier, vol. 7(3), pages 334-350, December.
    15. Koenker,Roger, 2005. "Quantile Regression," Cambridge Books, Cambridge University Press, number 9780521845731.
    16. Hausman, Jerry A., 1983. "Specification and estimation of simultaneous equation models," Handbook of Econometrics,in: Z. Griliches† & M. D. Intriligator (ed.), Handbook of Econometrics, edition 1, volume 1, chapter 7, pages 391-448 Elsevier.
    17. Jinyong Hahn & Jerry Hausman, 2003. "Weak Instruments: Diagnosis and Cures in Empirical Econometrics," American Economic Review, American Economic Association, vol. 93(2), pages 118-125, May.
    18. Victor Chernozhukov & Christian Hansen, 2004. "The Effects of 401(K) Participation on the Wealth Distribution: An Instrumental Quantile Regression Analysis," The Review of Economics and Statistics, MIT Press, vol. 86(3), pages 735-751, August.
    19. Charles L. Baum, 2009. "The effects of cigarette costs on BMI and obesity," Health Economics, John Wiley & Sons, Ltd., vol. 18(1), pages 3-19.
    20. Chou, Shin-Yi & Grossman, Michael & Saffer, Henry, 2004. "An economic analysis of adult obesity: results from the Behavioral Risk Factor Surveillance System," Journal of Health Economics, Elsevier, vol. 23(3), pages 565-587, May.
    21. Chou, Shin-Yi & Grossman, Michael & Saffer, Henry, 2006. "Reply to Jonathan Gruber and Michael Frakes," Journal of Health Economics, Elsevier, vol. 25(2), pages 389-393, March.
    22. Courtemanche, Charles, 2009. "Rising cigarette prices and rising obesity: Coincidence or unintended consequence?," Journal of Health Economics, Elsevier, vol. 28(4), pages 781-798, July.
    23. Rashad, Inas, 2006. "Structural estimation of caloric intake, exercise, smoking, and obesity," The Quarterly Review of Economics and Finance, Elsevier, vol. 46(2), pages 268-283, May.
    24. Euna Han & Edward C. Norton & Sally C. Stearns, 2009. "Weight and wages: fat versus lean paychecks," Health Economics, John Wiley & Sons, Ltd., vol. 18(5), pages 535-548.
    25. Cheng Kai-Wen & Kenkel Don S, 2010. "U.S. Cigarette Demand: 1944-2004," The B.E. Journal of Economic Analysis & Policy, De Gruyter, vol. 10(1), pages 1-21, August.
    26. Gruber, Jonathan & Frakes, Michael, 2006. "Does falling smoking lead to rising obesity?," Journal of Health Economics, Elsevier, vol. 25(2), pages 183-197, March.
    27. Chernozhukov, Victor & Hansen, Christian & Jansson, Michael, 2007. "Inference approaches for instrumental variable quantile regression," Economics Letters, Elsevier, vol. 95(2), pages 272-277, May.
    28. George L. Wehby & Jeffrey C. Murray & Eduardo E. Castilla & Jorge S. Lopez-Camelo & Robert L. Ohsfeldt, 2009. "Quantile effects of prenatal care utilization on birth weight in Argentina," Health Economics, John Wiley & Sons, Ltd., vol. 18(11), pages 1307-1321.
    29. Ding, Weili & Lehrer, Steven F. & Rosenquist, J.Niels & Audrain-McGovern, Janet, 2009. "The impact of poor health on academic performance: New evidence using genetic markers," Journal of Health Economics, Elsevier, vol. 28(3), pages 578-597, May.
    30. Chernozhukov, Victor & Hansen, Christian, 2006. "Instrumental quantile regression inference for structural and treatment effect models," Journal of Econometrics, Elsevier, vol. 132(2), pages 491-525, June.
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    Cited by:

    1. repec:eee:ehbiol:v:26:y:2017:i:c:p:96-111 is not listed on IDEAS
    2. repec:eee:jhecon:v:57:y:2018:i:c:p:31-44 is not listed on IDEAS
    3. Taylor, Amy E. & Davies, Neil M. & Ware, Jennifer J. & VanderWeele, Tyler & Smith, George Davey & Munafò, Marcus R., 2014. "Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates," Economics & Human Biology, Elsevier, vol. 13(C), pages 99-106.
    4. George Wehby & Allen Wilcox & Rolv Lie, 2013. "The impact of cigarette quitting during pregnancy on other prenatal health behaviors," Review of Economics of the Household, Springer, vol. 11(2), pages 211-233, June.
    5. Ricardo Goncalves & Peter J. Simmons & Yuanyuan Xie, 2017. "Rebel with(out) a cause? Inter-generational smoking dependence in Chinese households," Discussion Papers 17/20, Department of Economics, University of York.
    6. Dodd, Mark C., 2014. "Intertemporal discounting as a risk factor for high BMI: Evidence from Australia, 2008," Economics & Human Biology, Elsevier, vol. 12(C), pages 83-97.
    7. Srinivasan, C.S., 2013. "Can adherence to dietary guidelines address excess caloric intake? An empirical assessment for the UK," Economics & Human Biology, Elsevier, vol. 11(4), pages 574-591.
    8. Courtemanche, Charles & Tchernis, Rusty & Ukert, Benjamin, 2018. "The effect of smoking on obesity: Evidence from a randomized trial," Journal of Health Economics, Elsevier, vol. 57(C), pages 31-44.
    9. repec:pal:easeco:v:44:y:2018:i:2:d:10.1057_s41302-016-0071-0 is not listed on IDEAS

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