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AI in medical diagnosis: A contextualised study of patient motivations and concerns

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  • Hajiheydari, Nastaran
  • Delgosha, Mohammad Soltani
  • Saheb, Tahereh

Abstract

Patients' reactions to the implementation of Artificial Intelligence (AI) in healthcare range from adverse to favourable. While AI holds the promise of revolutionising healthcare by enhancing, accelerating, and improving the precision of care services, our understanding of patients' reactions to these paradigm shifts remains limited. In particular, little is known about the extent to which patients are receptive to independently use AI-enabled applications for diagnosis. This research seeks to develop a holistic, context-specific model capturing both the negative and positive cognitive responses of patients utilising AI-powered diagnostic services. Employing a sequential mixed-methods approach, the study draws on Behavioural Reasoning Theory to decode patients' cognitive reactions, including their reasons for and reasons giants using such applications. The research begins with a qualitative exploration, analysing user reviews to identify context-specific barriers and motivators. Building on these qualitative insights, the model's empirical validity is tested through a quantitative phase involving survey data analysis. Our findings provide a nuanced understanding of the context-dependent factors shaping patients' cognitive responses to AI-enabled diagnostic services, offering valuable insights for the design and implementation of patient-centred AI solutions in healthcare.

Suggested Citation

  • Hajiheydari, Nastaran & Delgosha, Mohammad Soltani & Saheb, Tahereh, 2025. "AI in medical diagnosis: A contextualised study of patient motivations and concerns," Social Science & Medicine, Elsevier, vol. 371(C).
  • Handle: RePEc:eee:socmed:v:371:y:2025:i:c:s0277953625001790
    DOI: 10.1016/j.socscimed.2025.117850
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    as
    1. Simonson, Itamar, 1989. "Choice Based on Reasons: The Case of Attraction and Compromise Effects," Journal of Consumer Research, Journal of Consumer Research Inc., vol. 16(2), pages 158-174, September.
    2. Christopher Robertson & Andrew Woods & Kelly Bergstrand & Jess Findley & Cayley Balser & Marvin J Slepian, 2023. "Diverse patients’ attitudes towards Artificial Intelligence (AI) in diagnosis," PLOS Digital Health, Public Library of Science, vol. 2(5), pages 1-16, May.
    3. Hardesty, David M. & Bearden, William O., 2004. "The use of expert judges in scale development: Implications for improving face validity of measures of unobservable constructs," Journal of Business Research, Elsevier, vol. 57(2), pages 98-107, February.
    4. Chiara Longoni & Andrea Bonezzi & Carey K Morewedge, 2019. "Resistance to Medical Artificial Intelligence," Journal of Consumer Research, Journal of Consumer Research Inc., vol. 46(4), pages 629-650.
    5. Jarrahi, Mohammad Hossein, 2018. "Artificial intelligence and the future of work: Human-AI symbiosis in organizational decision making," Business Horizons, Elsevier, vol. 61(4), pages 577-586.
    6. Tversky, Amos & Kahneman, Daniel, 1992. "Advances in Prospect Theory: Cumulative Representation of Uncertainty," Journal of Risk and Uncertainty, Springer, vol. 5(4), pages 297-323, October.
    7. Scott Mayer McKinney & Marcin Sieniek & Varun Godbole & Jonathan Godwin & Natasha Antropova & Hutan Ashrafian & Trevor Back & Mary Chesus & Greg S. Corrado & Ara Darzi & Mozziyar Etemadi & Florencia G, 2020. "International evaluation of an AI system for breast cancer screening," Nature, Nature, vol. 577(7788), pages 89-94, January.
    8. repec:dar:wpaper:137446 is not listed on IDEAS
    9. Alain Brémond & Marie-Odile Carrère & Nora Moumjid, 2007. "Seeking a second opinion: do patients need a second opinion when practice guidelines exist?," Post-Print halshs-00159795, HAL.
    10. Sarah Lebovitz & Hila Lifshitz-Assaf & Natalia Levina, 2022. "To Engage or Not to Engage with AI for Critical Judgments: How Professionals Deal with Opacity When Using AI for Medical Diagnosis," Organization Science, INFORMS, vol. 33(1), pages 126-148, January.
    11. Catherine Middleton & Rens Scheepers & Virpi Kristiina Tuunainen, 2014. "When mobile is the norm: researching mobile information systems and mobility as post-adoption phenomena," European Journal of Information Systems, Taylor & Francis Journals, vol. 23(5), pages 503-512, September.
    12. Camille Grange & Izak Benbasat, 2018. "Opinion seeking in a social network-enabled product review website: a study of word-of-mouth in the era of digital social networks," European Journal of Information Systems, Taylor & Francis Journals, vol. 27(6), pages 629-653, November.
    13. Street Jr., Richard L. & Gordon, Howard & Haidet, Paul, 2007. "Physicians' communication and perceptions of patients: Is it how they look, how they talk, or is it just the doctor?," Social Science & Medicine, Elsevier, vol. 65(3), pages 586-598, August.
    14. Delgosha, Mohammad Soltani & Hajiheydari, Nastaran, 2020. "On-demand service platforms pro/anti adoption cognition: Examining the context-specific reasons," Journal of Business Research, Elsevier, vol. 121(C), pages 180-194.
    15. Wenjuan Fan & Jingnan Liu & Shuwan Zhu & Panos M. Pardalos, 2020. "Investigating the impacting factors for the healthcare professionals to adopt artificial intelligence-based medical diagnosis support system (AIMDSS)," Annals of Operations Research, Springer, vol. 294(1), pages 567-592, November.
    16. De Togni, Giulia & Erikainen, Sonja & Chan, Sarah & Cunningham-Burley, Sarah, 2021. "What makes AI ‘intelligent’ and ‘caring’? Exploring affect and relationality across three sites of intelligence and care," Social Science & Medicine, Elsevier, vol. 277(C).
    17. Weiyin Hong & Frank K. Y. Chan & James Y. L. Thong & Lewis C. Chasalow & Gurpreet Dhillon, 2014. "A Framework and Guidelines for Context-Specific Theorizing in Information Systems Research," Information Systems Research, INFORMS, vol. 25(1), pages 111-136, March.
    18. Lysø, Emilie Hybertsen & Hesjedal, Maria Bårdsen & Skolbekken, John-Arne & Solbjør, Marit, 2024. "Men's sociotechnical imaginaries of artificial intelligence for prostate cancer diagnostics – A focus group study," Social Science & Medicine, Elsevier, vol. 347(C).
    19. Samuelson, William & Zeckhauser, Richard, 1988. "Status Quo Bias in Decision Making," Journal of Risk and Uncertainty, Springer, vol. 1(1), pages 7-59, March.
    20. Shahper Vodanovich & David Sundaram & Michael Myers, 2010. "Research Commentary ---Digital Natives and Ubiquitous Information Systems," Information Systems Research, INFORMS, vol. 21(4), pages 711-723, December.
    21. Westaby, James D., 2005. "Behavioral reasoning theory: Identifying new linkages underlying intentions and behavior," Organizational Behavior and Human Decision Processes, Elsevier, vol. 98(2), pages 97-120, November.
    22. Romain Cadario & Chiara Longoni & Carey K. Morewedge, 2021. "Understanding, explaining, and utilizing medical artificial intelligence," Nature Human Behaviour, Nature, vol. 5(12), pages 1636-1642, December.
    23. Weaver III, J.B. & Mays, D. & Weaver, S.S. & Hopkins, G.L. & Eroglu, D. & Bernhardt, J.M., 2010. "Health information-seeking behaviors, health indicators, and health risks," American Journal of Public Health, American Public Health Association, vol. 100(8), pages 1520-1525.
    24. Scott Mayer McKinney & Marcin Sieniek & Varun Godbole & Jonathan Godwin & Natasha Antropova & Hutan Ashrafian & Trevor Back & Mary Chesus & Greg S. Corrado & Ara Darzi & Mozziyar Etemadi & Florencia G, 2020. "Addendum: International evaluation of an AI system for breast cancer screening," Nature, Nature, vol. 586(7829), pages 19-19, October.
    25. Hajiheydari, Nastaran & Delgosha, Mohammad Soltani & Olya, Hossein, 2021. "Scepticism and resistance to IoMT in healthcare: Application of behavioural reasoning theory with configurational perspective," Technological Forecasting and Social Change, Elsevier, vol. 169(C).
    26. Siala, Haytham & Wang, Yichuan, 2022. "SHIFTing artificial intelligence to be responsible in healthcare: A systematic review," Social Science & Medicine, Elsevier, vol. 296(C).
    27. Ronald T. Cenfetelli & Andrew Schwarz, 2011. "Identifying and Testing the Inhibitors of Technology Usage Intentions," Information Systems Research, INFORMS, vol. 22(4), pages 808-823, December.
    28. Okazaki, Shintaro & Mendez, Felipe, 2013. "Perceived Ubiquity in Mobile Services," Journal of Interactive Marketing, Elsevier, vol. 27(2), pages 98-111.
    29. Gaube, Susanne & Biebl, Isabell & Engelmann, Magdalena Karin Maria & Kleine, Anne-Kathrin & Lermer, Eva, 2024. "Comparing preferences for skin cancer screening: AI-enabled app vs dermatologist," Social Science & Medicine, Elsevier, vol. 349(C).
    30. Anol Bhattacherjee & Sang Cheol Park, 2014. "Why end-users move to the cloud: a migration-theoretic analysis," European Journal of Information Systems, Taylor & Francis Journals, vol. 23(3), pages 357-372, May.
    31. Nima Kordzadeh & Maryam Ghasemaghaei, 2022. "Algorithmic bias: review, synthesis, and future research directions," European Journal of Information Systems, Taylor & Francis Journals, vol. 31(3), pages 388-409, May.
    32. Michael Breward & Khaled Hassanein & Milena Head, 2017. "Understanding Consumers’ Attitudes Toward Controversial Information Technologies: A Contextualization Approach," Information Systems Research, INFORMS, vol. 28(4), pages 760-774, December.
    33. Harrington, Nancy Grant & Scott, Allison M. & Spencer, Elizabeth A., 2020. "Working toward evidence-based guidelines for cost-of-care conversations between patients and physicians: A systematic review of the literature," Social Science & Medicine, Elsevier, vol. 258(C).
    34. Wang, Weisha & Wang, Yichuan & Chen, Long & Ma, Rui & Zhang, Minhao, 2024. "Justice at the Forefront: Cultivating felt accountability towards Artificial Intelligence among healthcare professionals," Social Science & Medicine, Elsevier, vol. 347(C).
    35. Roozmehr Safi & Yang Yu, 2017. "Online product review as an indicator of users’ degree of innovativeness and product adoption time: a longitudinal analysis of text reviews," European Journal of Information Systems, Taylor & Francis Journals, vol. 26(4), pages 414-431, July.
    36. Jonas Schmidt & Tammo H. A. Bijmolt, 2020. "Accurately measuring willingness to pay for consumer goods: a meta-analysis of the hypothetical bias," Journal of the Academy of Marketing Science, Springer, vol. 48(3), pages 499-518, May.
    37. Ekaterina Jussupow & Kai Spohrer & Armin Heinzl & Joshua Gawlitza, 2021. "Augmenting Medical Diagnosis Decisions? An Investigation into Physicians’ Decision-Making Process with Artificial Intelligence," Information Systems Research, INFORMS, vol. 32(3), pages 713-735, September.
    38. Moumjid, Nora & Gafni, Amiram & Bremond, Alain & Carrere, Marie-Odile, 2007. "Seeking a second opinion: Do patients need a second opinion when practice guidelines exist?," Health Policy, Elsevier, vol. 80(1), pages 43-50, January.
    39. Jinxin Pan & Shuai Ding & Desheng Wu & Shanlin Yang & Jun Yang, 2019. "Exploring behavioural intentions toward smart healthcare services among medical practitioners: a technology transfer perspective," International Journal of Production Research, Taylor & Francis Journals, vol. 57(18), pages 5801-5820, September.
    40. Caroline Steigenberger & Magdalena Flatscher-Thoeni & Uwe Siebert & Andrea M. Leiter, 2022. "Determinants of willingness to pay for health services: a systematic review of contingent valuation studies," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 23(9), pages 1455-1482, December.
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