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R&D portfolios and pharmaceutical licensing

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  • Nishimura, Junichi
  • Okada, Yosuke

Abstract

We examine how R&D portfolios of drug pipelines affect pharmaceutical licensing, controlling firm size, diversity, and competition. The data collected comprises 434 license-ins and 329 license-outs closed by 54 Japanese pharmaceutical companies between 1997 and 2007. We pay special attention to stage-specific licensing by dividing the innovation process into early and late stages. Joint estimates of license-in and license-out using seemingly unrelated regressions (SUR) reveal that drug pipelines significantly affect stage-specific licensing, inducing portfolio effect that lead to smoothing drug pipelines across early and late stages.

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  • Nishimura, Junichi & Okada, Yosuke, 2014. "R&D portfolios and pharmaceutical licensing," Research Policy, Elsevier, vol. 43(7), pages 1250-1263.
    • Handle: RePEc:eee:respol:v:43:y:2014:i:7:p:1250-1263
    DOI: 10.1016/j.respol.2014.03.008
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    4. Ming Li & Xiangdong Chen & Gupeng Zhang, 2017. "How does firm size affect technology licensing? Empirical evidence from China," Scientometrics, Springer;Akadémiai Kiadó, vol. 112(3), pages 1249-1269, September.
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    6. Fernando Gascón & Jesús Lozano & Borja Ponte & David Fuente, 2017. "Measuring the efficiency of large pharmaceutical companies: an industry analysis," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 18(5), pages 587-608, June.
    7. Subramanian, Annapoornima M. & Bo, Wang & Kah-Hin, Chai, 2018. "The role of knowledge base homogeneity in learning from strategic alliances," Research Policy, Elsevier, vol. 47(1), pages 158-168.
    8. Klueter, Thomas & Monteiro, L. Felipe & Dunlap, Denise R., 2017. "Standard vs. partnership-embedded licensing: Attention and the relationship between licensing and product innovations," Research Policy, Elsevier, vol. 46(9), pages 1629-1643.
    9. Purdy, Lauren & Eslami, Hadi & Eshghi, Kamran & Rod, Michel, 2023. "Technology sourcing and the dark side of open innovation: Evidence from the biopharmaceutical sector," Technovation, Elsevier, vol. 119(C).
    10. Yu, Xinning & Lan, Yanfei & Zhao, Ruiqing, 2021. "Strategic green technology innovation in a two-stage alliance: Vertical collaboration or co-development?," Omega, Elsevier, vol. 98(C).
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    More about this item

    Keywords

    R&D portfolios; Licensing; Pharmaceutical industry; Drug pipelines;
    All these keywords.

    JEL classification:

    • C13 - Mathematical and Quantitative Methods - - Econometric and Statistical Methods and Methodology: General - - - Estimation: General
    • L24 - Industrial Organization - - Firm Objectives, Organization, and Behavior - - - Contracting Out; Joint Ventures
    • L65 - Industrial Organization - - Industry Studies: Manufacturing - - - Chemicals; Rubber; Drugs; Biotechnology; Plastics

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