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The effect of local growth in antidepressant consumption on mental health outcomes

Author

Listed:
  • Giuliano Masiero

    (Department of Management, Information and Production Engineering, University of Bergamo, Italy; Institute of Economics (IdEP), Università della Svizzera italiana, Switzerland)

  • Fabrizio Mazzonna

    (Institute of Economics (IdEP), Università della Svizzera italiana, Switzerland, and Munich Center for the Economics of Aging (MEA))

  • Sandro Steinbach

    (Department of Agricultural and Resource Economics, University of Connecticut, United States)

  • Olaf Verbeek

    (Institute of Economics (IdEP), Università della Svizzera italiana, Switzerland)

Abstract

Despite growing skepticism regarding the efficacy of antidepressants, global consumption is increasing at an unprecedented path with unknown implications for society. We estimate the causal effect of this increase on mental health outcomes using an IV strategy that exploits detailed drug sales data from Switzerland between 2002 and 2014. Our instrument, a modified version of the popular shift-share instrument, relies on the national growth in antidepressant sales for pharmaceutical companies (the shift) - mainly due to product innovation - and assigns it locally using regional non-antidepressant market shares. Our estimates show that an increase in antidepressants sales does not significantly affect suicide rates but cause an increase of hospital admissions for mental disorder and for depression. The causal effects prove to be resistant to several robustness checks.

Suggested Citation

  • Giuliano Masiero & Fabrizio Mazzonna & Sandro Steinbach & Olaf Verbeek, 2019. "The effect of local growth in antidepressant consumption on mental health outcomes," IdEP Economic Papers 1902, USI Università della Svizzera italiana.
  • Handle: RePEc:lug:wpidep:1902
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    References listed on IDEAS

    as
    1. Ludwig, Jens & Marcotte, Dave E. & Norberg, Karen, 2009. "Anti-depressants and suicide," Journal of Health Economics, Elsevier, vol. 28(3), pages 659-676, May.
    2. Terza, Joseph V. & Basu, Anirban & Rathouz, Paul J., 2008. "Two-stage residual inclusion estimation: Addressing endogeneity in health econometric modeling," Journal of Health Economics, Elsevier, vol. 27(3), pages 531-543, May.
    3. Irving Kirsch & Brett J Deacon & Tania B Huedo-Medina & Alan Scoboria & Thomas J Moore & Blair T Johnson, 2008. "Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration," PLOS Medicine, Public Library of Science, vol. 5(2), pages 1-9, February.
    4. Gary Solon & Steven J. Haider & Jeffrey M. Wooldridge, 2015. "What Are We Weighting For?," Journal of Human Resources, University of Wisconsin Press, vol. 50(2), pages 301-316.
    5. Paul Goldsmith-Pinkham & Isaac Sorkin & Henry Swift, 2020. "Bartik Instruments: What, When, Why, and How," American Economic Review, American Economic Association, vol. 110(8), pages 2586-2624, August.
    6. Susan H. Busch & Ezra Golberstein & Ellen Meara, 2014. "The FDA and ABCs: Unintended Consequences of Antidepressant Warnings on Human Capital," Journal of Human Resources, University of Wisconsin Press, vol. 49(3), pages 540-557.
    7. Stuhler, Jan & Jaeger, David & Ruist, Joakim, 2018. "Shift-Share Instruments and the Impact of Immigration," CEPR Discussion Papers 12701, C.E.P.R. Discussion Papers.
    8. Timothy J. Bartik, 1991. "Who Benefits from State and Local Economic Development Policies?," Books from Upjohn Press, W.E. Upjohn Institute for Employment Research, number wbsle, August.
    9. Giuliano Masiero & Fabrizio Mazzonna & Olaf Verbeek, 2018. "What drives the rise of antidepressant consumption? Evidence from Switzerland," IdEP Economic Papers 1801, USI Università della Svizzera italiana.
    Full references (including those not matched with items on IDEAS)

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    More about this item

    Keywords

    Depression; Antidepressant treatment; Suicides; Mental health;
    All these keywords.

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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    This paper has been announced in the following NEP Reports:

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