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The more you spend, the more you get? The effects of R&D and capital expenditures on the patenting activities of biotechnology firms

Author

Listed:
  • Roberta Piergiovanni

    (Istat-Sede per l’Emilia-Romagna)

  • Enrico Santarelli

    (University of Bologna
    European Commission, Joint Research Centre (JRC), Institute for Prospective Technological Studies (IPTS))

Abstract

This paper provides evidence on the mechanisms influencing the patent output of a sample of small and large, entrepreneurial and established biotechnology firms from the input of indirect knowledge acquired from capital expenditures and direct knowledge from in-house R&D. Statistical models of counts are used to analyse the relationship between patent applications and R&D investment and capital expenditures. It focuses on biotechnology in the period 2002–2007 and is based on a unique data set drawn from various sources including the EU Industrial R&D Investment Scoreboard, the European Patent Office (EPO), the US Patent and Trademark Office, and the World Intellectual Property Organisation. The statistical models employed in the paper are Poisson distribution generalisations with the actual distribution of patent counts fitting the negative binomial distribution and gamma distribution very well. Findings support the idea that capital expenditures—taken as equivalent to technical change embodied in new machinery and capital equipment—may also play a crucial role in the development of new patentable items from scientific companies. For EPO patents, this role appears even more important than that played by R&D investment. The overall picture emerging from our analysis of the determinants of patenting in biotechnology is that the innovation process involves a well balanced combination of inputs from both R&D and new machinery and capital equipment.

Suggested Citation

  • Roberta Piergiovanni & Enrico Santarelli, 2013. "The more you spend, the more you get? The effects of R&D and capital expenditures on the patenting activities of biotechnology firms," Scientometrics, Springer;Akadémiai Kiadó, vol. 94(2), pages 497-521, February.
  • Handle: RePEc:spr:scient:v:94:y:2013:i:2:d:10.1007_s11192-012-0711-z
    DOI: 10.1007/s11192-012-0711-z
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    1. Davit Khachatryan & Brigitte Muehlmann, 2017. "Determinants of successful patent applications to combat financial fraud," Scientometrics, Springer;Akadémiai Kiadó, vol. 111(3), pages 1353-1383, June.
    2. Csomós György, 2017. "Mapping Spatial and Temporal Changes of Global Corporate Research and Development Activities by Conducting a Bibliometric Analysis," Quaestiones Geographicae, Sciendo, vol. 36(1), pages 65-77, March.
    3. Csomós, György & Tóth, Géza, 2016. "Exploring the position of cities in global corporate research and development: A bibliometric analysis by two different geographical approaches," Journal of Informetrics, Elsevier, vol. 10(2), pages 516-532.
    4. Chojnacki, Piotr & Kijek, Tomasz, 2014. "R&D Expenditures And Market Value Of Biotechnology Firms," Roczniki (Annals), Polish Association of Agricultural Economists and Agribusiness - Stowarzyszenie Ekonomistow Rolnictwa e Agrobiznesu (SERiA), vol. 2014(6).
    5. Kotiranta, Annu – Kulvik & Tahvanainen, Antti – Trieste, . "Raiders Of Lost Value," ETLA B, The Research Institute of the Finnish Economy, number 267.
    6. Ferreira, Paulo Jorge Silveira & Dionísio, Andreia Teixeira Marques, 2016. "What are the conditions for good innovation results? A fuzzy-set approach for European Union," Journal of Business Research, Elsevier, vol. 69(11), pages 5396-5400.
    7. Enrico Santarelli & Hien Thu Tran, 2017. "Young innovative companies: Are they high performers in transition economies? Evidence for Vietnam," The Journal of Technology Transfer, Springer, vol. 42(5), pages 1052-1076, October.

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    More about this item

    Keywords

    Patents; R&D; Capital expenditure; Poisson models; Biotechnology;
    All these keywords.

    JEL classification:

    • L25 - Industrial Organization - - Firm Objectives, Organization, and Behavior - - - Firm Performance
    • L65 - Industrial Organization - - Industry Studies: Manufacturing - - - Chemicals; Rubber; Drugs; Biotechnology; Plastics
    • O34 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Intellectual Property and Intellectual Capital

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