Institutional entrepreneurship in constructing alternative paths: A comparison of biotech hybrids
This paper investigates how firms adapt their innovation strategies to cope with constraints in national institutional environments. It is a comparative case study of Dutch and British dedicated biotechnology firms focusing on a particular type of strategy, the hybrid model. Patterns of skill accumulation and learning present in the Dutch hybrids are indications of how they use institutional advantages to focus on low-risk innovation and build deeper competences while also pursuing high-risk innovation strategies. The Dutch hybrid model offers insight into how firms comply with the dominant logic of the biotechnology field even when their institutional frameworks encourage the pursuit of low-risk innovation strategies.
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- Casper, Steven, 2007. "How do technology clusters emerge and become sustainable?: Social network formation and inter-firm mobility within the San Diego biotechnology cluster," Research Policy, Elsevier, vol. 36(4), pages 438-455, May.
- Casper, Steven & Whitley, Richard, 2004. "Managing competences in entrepreneurial technology firms: a comparative institutional analysis of Germany, Sweden and the UK," Research Policy, Elsevier, vol. 33(1), pages 89-106, January.
- Nelson, Richard R. & Nelson, Katherine, 2002. "Technology, institutions, and innovation systems," Research Policy, Elsevier, vol. 31(2), pages 265-272, February.
- Deeds, David L. & Decarolis, Dona & Coombs, Joseph E., 1997. "The impact of firmspecific capabilities on the amount of capital raised in an initial public offering: Evidence from the biotechnology industry," Journal of Business Venturing, Elsevier, vol. 12(1), pages 31-46, January.
- Benjamin Coriat & Fabienne Orsi & Olivier Weinstein, 2003. "Does Biotech Reflect a New Science-based Innovation Regime?," Industry and Innovation, Taylor & Francis Journals, vol. 10(3), pages 231-253.
- Lundvall, Bengt-Ake & Johnson, Bjorn & Andersen, Esben Sloth & Dalum, Bent, 2002. "National systems of production, innovation and competence building," Research Policy, Elsevier, vol. 31(2), pages 213-231, February.
- Arora, Ashish & Gambardella, Alfonso, 1990. "Complementarity and External Linkages: The Strategies of the Large Firms in Biotechnology," Journal of Industrial Economics, Wiley Blackwell, vol. 38(4), pages 361-79, June.
- Marsili, O., 2000. "Technological regimes and sources of entrepreneurship," Working Papers 00.10, Eindhoven Center for Innovation Studies.
- Whitley, Richard, 2007. "Business Systems and Organizational Capabilities: The Institutional Structuring of Competitive Competences," OUP Catalogue, Oxford University Press, number 9780199205189, March.
- Steven Casper & Anastasios Karamanos, 2003. "Commercializing Science in Europe: The Cambridge Biotechnology Cluster," European Planning Studies, Taylor & Francis Journals, vol. 11(7), pages 805-822, October.
- Taylor, Mark Zachary, 2004. "Empirical Evidence Against Varieties of Capitalism's Theory of Technological Innovation," International Organization, Cambridge University Press, vol. 58(03), pages 601-631, July.
- Baum, Joel A. C. & Silverman, Brian S., 2004. "Picking winners or building them? Alliance, intellectual, and human capital as selection criteria in venture financing and performance of biotechnology startups," Journal of Business Venturing, Elsevier, vol. 19(3), pages 411-436, May.
- Bozeman, Barry & Gaughan, Monica, 2007. "Impacts of grants and contracts on academic researchers' interactions with industry," Research Policy, Elsevier, vol. 36(5), pages 694-707, June.
- Casper, Steven, 2007. "Creating Silicon Valley in Europe: Public Policy Towards New Technology Industries," OUP Catalogue, Oxford University Press, number 9780199269525, March.
- Paul Almeida & Bruce Kogut, 1999. "Localization of Knowledge and the Mobility of Engineers in Regional Networks," Management Science, INFORMS, vol. 45(7), pages 905-917, July.
- Hopkins, Michael M. & Martin, Paul A. & Nightingale, Paul & Kraft, Alison & Mahdi, Surya, 2007. "The myth of the biotech revolution: An assessment of technological, clinical and organisational change," Research Policy, Elsevier, vol. 36(4), pages 566-589, May.
- Franco Malerba & Luigi Orsenigo, 2002. "Innovation and market structure in the dynamics of the pharmaceutical industry and biotechnology: towards a history-friendly model," Industrial and Corporate Change, Oxford University Press, vol. 11(4), pages 667-703, August.
- Malerba, Franco, 2002. "Sectoral systems of innovation and production," Research Policy, Elsevier, vol. 31(2), pages 247-264, February.
- Steven Casper & Hannah Kettler, 2001. "National Institutional Frameworks And The Hybridization Of Entrepreneurial Business Models: The German And Uk Biotechnology Sectors," Industry and Innovation, Taylor & Francis Journals, vol. 8(1), pages 5-30.
- Gittelman, Michelle, 2006. "National institutions, public-private knowledge flows, and innovation performance: A comparative study of the biotechnology industry in the US and France," Research Policy, Elsevier, vol. 35(7), pages 1052-1068, September.
- Bassanini, Andrea & Ernst, Ekkehard, 2001.
"Labour market regulation, industrial relations, and technological regimes: a tale of comparative advantage,"
CEPREMAP Working Papers (Couverture Orange)
- Andrea Bassanini & Ekkehard Ernst, 2002. "Labour market regulation, industrial relations and technological regimes: a tale of comparative advantage," Industrial and Corporate Change, Oxford University Press, vol. 11(3), pages 391-426, June.
- Carlsson, Bo, 2006. "Internationalization of innovation systems: A survey of the literature," Research Policy, Elsevier, vol. 35(1), pages 56-67, February.
- Amable, Bruno, 2003. "The Diversity of Modern Capitalism," OUP Catalogue, Oxford University Press, number 9780199261147, March.
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