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Inventive and uninventive clusters: The case of Canadian biotechnology

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  • Aharonson, Barak S.
  • Baum, Joel A.C.
  • Plunket, Anne

Abstract

We examine factors influencing the relative productivity of different geographic locations. Our analysis of the Canadian biotechnology industry during the 1990s reveals that inventive and uninventive locations are distinguishable within small geographic areas corresponding to roughly 7000 postal addresses. Inventive locations exhibit greater resource scale and technological focus, as well as greater emphasis on R&D investment and public and private collaboration. Comparison of inventive locations across three major metropolitan areas - Vancouver, Toronto and Montreal - indicates, however, that inventive locations vary in their emphasis on technological scale and focus relative to collaboration, and thus that location advantages can develop in distinctive ways.

Suggested Citation

  • Aharonson, Barak S. & Baum, Joel A.C. & Plunket, Anne, 2008. "Inventive and uninventive clusters: The case of Canadian biotechnology," Research Policy, Elsevier, vol. 37(6-7), pages 1108-1131, July.
  • Handle: RePEc:eee:respol:v:37:y:2008:i:6-7:p:1108-1131
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    1. Romer, Paul M, 1986. "Increasing Returns and Long-run Growth," Journal of Political Economy, University of Chicago Press, vol. 94(5), pages 1002-1037, October.
    2. Rebecca Henderson & Iain Cockburn, 1996. "Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery," RAND Journal of Economics, The RAND Corporation, vol. 27(1), pages 32-59, Spring.
    3. Catherine Beaudry & Stefano Breschi, 2003. "Are firms in clusters really more innovative?," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 12(4), pages 325-342.
    4. Lori Rosenkopf & Paul Almeida, 2003. "Overcoming Local Search Through Alliances and Mobility," Management Science, INFORMS, vol. 49(6), pages 751-766, June.
    5. Feldman, Maryann P. & Audretsch, David B., 1999. "Innovation in cities:: Science-based diversity, specialization and localized competition," European Economic Review, Elsevier, vol. 43(2), pages 409-429, February.
    6. Davidson, Russell & MacKinnon, James G., 1993. "Estimation and Inference in Econometrics," OUP Catalogue, Oxford University Press, number 9780195060119.
    7. Rothaermel, Frank T. & Thursby, Marie, 2005. "Incubator firm failure or graduation?: The role of university linkages," Research Policy, Elsevier, vol. 34(7), pages 1076-1090, September.
    8. Steven Globerman & Daniel Shapiro & Aidan Vining, 2005. "Clusters and intercluster spillovers: their influence on the growth and survival of Canadian information technology firms," Industrial and Corporate Change, Oxford University Press, vol. 14(1), pages 27-60, February.
    9. Stuart S. Rosenthal & William C. Strange, 2003. "Geography, Industrial Organization, and Agglomeration," The Review of Economics and Statistics, MIT Press, vol. 85(2), pages 377-393, May.
    10. Lerner, Josh & Merges, Robert P, 1998. "The Control of Technology Alliances: An Empirical Analysis of the Biotechnology Industry," Journal of Industrial Economics, Wiley Blackwell, vol. 46(2), pages 125-156, June.
    11. Adam B. Jaffe & Manuel Trajtenberg & Rebecca Henderson, 1993. "Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations," The Quarterly Journal of Economics, Oxford University Press, vol. 108(3), pages 577-598.
    12. Heckman, James, 2013. "Sample selection bias as a specification error," Applied Econometrics, Publishing House "SINERGIA PRESS", vol. 31(3), pages 129-137.
    13. Catherine Beaudry, 2001. "Entry, Growth and Patenting in Industrial Clusters: A Study of the Aerospace Industry in the UK," International Journal of the Economics of Business, Taylor & Francis Journals, vol. 8(3), pages 405-436.
    14. Giovanni Dosi & Christopher Freeman & Richard Nelson & Gerarld Silverberg & Luc Soete (ed.), 1988. "Technical Change and Economic Theory," LEM Book Series, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy, number dosietal-1988, August.
    15. Anselin, Luc & Varga, Attila & Acs, Zoltan, 1997. "Local Geographic Spillovers between University Research and High Technology Innovations," Journal of Urban Economics, Elsevier, vol. 42(3), pages 422-448, November.
    16. Wallsten, Scott J., 2001. "An empirical test of geographic knowledge spillovers using geographic information systems and firm-level data," Regional Science and Urban Economics, Elsevier, vol. 31(5), pages 571-599, September.
    17. Mariani, Myriam, 2004. "What determines technological hits?: Geography versus firm competencies," Research Policy, Elsevier, vol. 33(10), pages 1565-1582, December.
    18. McGahan, Anita M. & Silverman, Brian S., 2006. "Profiting from technological innovation by others: The effect of competitor patenting on firm value," Research Policy, Elsevier, vol. 35(8), pages 1222-1242, October.
    19. Baptista, Rui & Swann, Peter, 1998. "Do firms in clusters innovate more?," Research Policy, Elsevier, vol. 27(5), pages 525-540, September.
    20. Argyres, Nicholas S. & Liebeskind, Julia Porter, 1998. "Privatizing the intellectual commons: Universities and the commercialization of biotechnology," Journal of Economic Behavior & Organization, Elsevier, vol. 35(4), pages 427-454, May.
    21. Stuart, Toby & Sorenson, Olav, 2003. "The geography of opportunity: spatial heterogeneity in founding rates and the performance of biotechnology firms," Research Policy, Elsevier, vol. 32(2), pages 229-253, February.
    22. Zucker, Lynne G & Darby, Michael R & Armstrong, Jeff, 1998. "Geographically Localized Knowledge: Spillovers or Markets?," Economic Inquiry, Western Economic Association International, vol. 36(1), pages 65-86, January.
    23. Heckman, James J & Borjas, George J, 1980. "Does Unemployment Cause Future Unemployment? Definitions, Questions and Answers from a Continuous Time Model of Heterogeneity and State Dependence," Economica, London School of Economics and Political Science, vol. 47(187), pages 247-283, August.
    24. Klepper, Steven, 1996. "Entry, Exit, Growth, and Innovation over the Product Life Cycle," American Economic Review, American Economic Association, vol. 86(3), pages 562-583, June.
    25. Zucker, Lynne G & Darby, Michael R & Brewer, Marilynn B, 1998. "Intellectual Human Capital and the Birth of U.S. Biotechnology Enterprises," American Economic Review, American Economic Association, vol. 88(1), pages 290-306, March.
    26. Robert Jacobson, 1990. "Unobservable Effects and Business Performance," Marketing Science, INFORMS, vol. 9(1), pages 74-85.
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    Cited by:

    1. Uwe Cantner & Holger Graf & Susanne Hinzmann, 2013. "Policy induced innovation networks: the case of the German "Leading-Edge Cluster competition"," Jena Economic Research Papers 2013-008, Friedrich-Schiller-University Jena.
    2. Delgado, Mercedes & Porter, Michael E. & Stern, Scott, 2014. "Clusters, convergence, and economic performance," Research Policy, Elsevier, vol. 43(10), pages 1785-1799.
    3. Karna, Amit & Florian A. Taeube & Petra Sonderegger, 2014. "Economic Geography and Networks: Role of local and non-local ties in Cluster Evolution," IIMA Working Papers WP2014-12-01, Indian Institute of Management Ahmedabad, Research and Publication Department.
    4. Ana Paula Faria & Natália Barbosa & Vasco Eiriz, 2013. "Firms’ innovation across regions: an exploratory study," NIPE Working Papers 12/2013, NIPE - Universidade do Minho.
    5. Kolympiris, Christos & Kalaitzandonakes, Nicholas & Miller, Douglas, 2014. "Public funds and local biotechnology firm creation," Research Policy, Elsevier, vol. 43(1), pages 121-137.
    6. Filip De Beule & Ilke Van Beveren, 2008. "Product innovation and renewal: foreign firms and clusters in Belgium," LICOS Discussion Papers 22709, LICOS - Centre for Institutions and Economic Performance, KU Leuven.
    7. Cassi, Lorenzo & Plunket, Anne, 2010. "The determinants of co-inventor tie formation: proximity and network dynamics," MPRA Paper 27303, University Library of Munich, Germany.
    8. Ana Paula Faria & Natália Barbosa & Vasco Eiriz, 2015. "Firm Innovation and Co-Location in Portugal," Growth and Change, Wiley Blackwell, vol. 46(4), pages 574-592, December.
    9. Lorenzo Cassi & Anne Plunket, 2015. "Research Collaboration in Co-inventor Networks: Combining Closure, Bridging and Proximities," Regional Studies, Taylor & Francis Journals, vol. 49(6), pages 936-954, June.
    10. Eisingerich, Andreas B. & Bell, Simon J. & Tracey, Paul, 2010. "How can clusters sustain performance? The role of network strength, network openness, and environmental uncertainty," Research Policy, Elsevier, vol. 39(2), pages 239-253, March.
    11. Gilbert, Brett Anitra & Campbell, Joanna Tochman, 2015. "The geographic origins of radical technological paradigms: A configurational study," Research Policy, Elsevier, vol. 44(2), pages 311-327.
    12. Anne Plunket, 2009. "Firms’ inventiveness and localized vertical R&D spillovers," Journal of Innovation Economics, De Boeck Université, vol. 0(2), pages 147-170.
    13. Audia, Pino G. & Rider, Christopher I., 2010. "Close, but not the same: Locally headquartered organizations and agglomeration economies in a declining industry," Research Policy, Elsevier, vol. 39(3), pages 360-374, April.
    14. Uwe Cantner & Holger Graf & Susanne Hinzmann, 2015. "The role of geographical proximity for project performance - Evidence from the German "Leading-Edge Cluster Competition"," Jena Economic Research Papers 2015-025, Friedrich-Schiller-University Jena.
    15. F. Xavier Molina-Morales & Josep Capó-Vicedo & M. Teresa Martínez-Fernández & Manuel Expósito-Langa, 2013. "Social capital in industrial districts: Influence of the strength of ties and density of the network on the sense of belonging to the district," Papers in Regional Science, Wiley Blackwell, vol. 92(4), pages 773-789, November.
    16. Gilbert, Brett Anitra, 2012. "Creative destruction: Identifying its geographic origins," Research Policy, Elsevier, vol. 41(4), pages 734-742.

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