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How COVID‐19 vaccine supply chains emerged in the midst of a pandemic

Author

Listed:
  • Chad P. Bown
  • Thomas J. Bollyky

Abstract

Many months after COVID‐19 vaccines were first authorised for public use, still limited supplies could only partially reduce the devastating loss of life and economic costs caused by the pandemic. Could additional vaccine doses have been manufactured more quickly some other way? Would alternative policy choices have made a difference? This paper provides a simple analytical framework through which to view the contours of the vaccine value chain. It then creates a new database that maps the COVID‐19 vaccines of Pfizer/BioNTech, Moderna, AstraZeneca/Oxford, Johnson & Johnson, Novavax and CureVac to the product‐ and location‐specific manufacturing supply chains that emerged in 2020 and 2021. It describes the choppy process through which dozens of other companies at nearly 100 geographically distributed facilities came together to scale up global manufacturing. The paper catalogues major pandemic policy initiatives – such as the United States' Operation Warp Speed – that are likely to have affected the timing and formation of those vaccine supply chains. Given the data, a final section identifies further questions for researchers and policymakers.

Suggested Citation

  • Chad P. Bown & Thomas J. Bollyky, 2022. "How COVID‐19 vaccine supply chains emerged in the midst of a pandemic," The World Economy, Wiley Blackwell, vol. 45(2), pages 468-522, February.
  • Handle: RePEc:bla:worlde:v:45:y:2022:i:2:p:468-522
    DOI: 10.1111/twec.13183
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    References listed on IDEAS

    as
    1. Michael Kremer & Jonathan Levin & Christopher M. Snyder, 2022. "Designing Advance Market Commitments for New Vaccines," Management Science, INFORMS, vol. 68(7), pages 4786-4814, July.
    2. Cem Çakmaklı & Selva Demiralp & Ṣebnem Kalemli-Özcan & Sevcan Yeşiltaş & Muhammed A. Yıldırım, 2021. "The Economic Case for Global Vaccinations: An Epidemiological Model with International Production Networks," NBER Working Papers 28395, National Bureau of Economic Research, Inc.
    3. Chad Bown, 2020. "How the United States Marched the Semiconductor Industry into Its Trade War with China," East Asian Economic Review, Korea Institute for International Economic Policy, vol. 24(4), pages 349-388.
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    Citations

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    Cited by:

    1. Arthur Buitenen & Arco Timmermans & Gerard Breeman, 2025. "Revealing private interests of non-state actor coalitions in negotiating access and benefit sharing," International Environmental Agreements: Politics, Law and Economics, Springer, vol. 25(3), pages 469-488, September.
    2. Pierre Cotterlaz & Guillaume Gaulier & Aude Sztulman & Deniz Ünal, 2024. "Pioneering a new classification: a comprehensive study of healthcare products in global trade," Working Papers 2024-02, CEPII research center.
    3. Yu, Guihai & Kang, Yuwei & Li, Xiaopeng & Perc, Matjaž & Završnik, Jernej, 2026. "Evolution of global healthcare trade networks: Structural fracture detection, topological responses, and cross-commodity dependency restructuring," Chaos, Solitons & Fractals, Elsevier, vol. 202(P1).
    4. Bustamante, Juana & Oughton, Christine & Pesque-Cela, Vanesa & Tobin, Damian, 2023. "Resolving the patents paradox in the era of COVID-19 and climate change: Towards a patents taxonomy," Research Policy, Elsevier, vol. 52(9).
    5. Karakaya, Sırma & Balcik, Burcu, 2024. "Developing a national pandemic vaccination calendar under supply uncertainty," Omega, Elsevier, vol. 124(C).
    6. An Pham Ngoc Nguyen & Martin Crane & Thomas Conlon & Marija Bezbradica, 2025. "Herding unmasked: Insights into cryptocurrencies, stocks and US ETFs," PLOS ONE, Public Library of Science, vol. 20(2), pages 1-49, February.
    7. Cotterlaz, Pierre & Gaulier, Guillaume & Sztulman, Aude & Ünal, Deniz, 2024. "Broadening the definition of healthcare products in global trade: Insights from a new classification," International Economics, Elsevier, vol. 180(C).
    8. Fonseca, Elize Massard da & Shadlen, Kenneth C. & Achcar, Helena de Moraes, 2023. "Vaccine technology transfer in a global health crisis: Actors, capabilities, and institutions," Research Policy, Elsevier, vol. 52(4).
    9. An Pham Ngoc Nguyen & Marija Bezbradica & Martin Crane, 2025. "Community-level Contagion among Diverse Financial Assets," Papers 2509.15232, arXiv.org, revised Jan 2026.
    10. Sariahmed, Karim & Graham, Janice E. & Herder, Matthew & Morten, Christopher J., 2025. "Public sector innovation and the constraints of ‘platform thinking’: An account of Johnson & Johnson's adenoviral vector vaccines," Social Science & Medicine, Elsevier, vol. 387(C).
    11. Sudhanshu Joshi & Manu Sharma, 2022. "A Literature Survey on Vaccine Supply Chain Management Amidst COVID-19: Literature Developments, Future Directions and Open Challenges for Public Health," World, MDPI, vol. 3(4), pages 1-28, October.

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    JEL classification:

    • F13 - International Economics - - Trade - - - Trade Policy; International Trade Organizations

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