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Series handle: RePEc:plo:pgen00

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Content

December 2019, Volume 15, Issue 12

1-24 Leveraging allelic imbalance to refine fine-mapping for eQTL studies
by Jennifer Zou & Farhad Hormozdiari & Brandon Jew & Stephane E Castel & Tuuli Lappalainen & Jason Ernst & Jae Hoon Sul & Eleazar Eskin
1-34 Common gardens in teosintes reveal the establishment of a syndrome of adaptation to altitude
by Margaux-Alison Fustier & Natalia E Martínez-Ainsworth & Jonás A Aguirre-Liguori & Anthony Venon & Hélène Corti & Agnès Rousselet & Fabrice Dumas & Hannes Dittberner & María G Camarena & Daniel Grimanelli & Otso Ovaskainen & Matthieu Falque & Laurence Moreau & Juliette de Meaux & Salvador Montes-Hernández & Luis E Eguiarte & Yves Vigouroux & Domenica Manicacci & Maud I Tenaillon

November 2019, Volume 15, Issue 11

1-15 Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies
by Andrew Schlafly & Ruth M Pfeiffer & Eduardo Nagore & Susana Puig & Donato Calista & Paola Ghiorzo & Chiara Menin & Maria Concetta Fargnoli & Ketty Peris & Lei Song & Tongwu Zhang & Jianxin Shi & Maria Teresa Landi & Joshua Neil Sampson
1-21 Inference of recombination maps from a single pair of genomes and its application to ancient samples
by Gustavo V. Barroso & Nataša Puzović & Julien Y Dutheil
1-24 UMAP reveals cryptic population structure and phenotype heterogeneity in large genomic cohorts
by Alex Diaz-Papkovich & Luke Anderson-Trocmé & Chief Ben-Eghan & Simon Gravel
1-30 A meta-analysis of genome-wide association studies of epigenetic age acceleration
by Jude Gibson & Tom C Russ & Toni-Kim Clarke & David M Howard & Robert F Hillary & Kathryn L Evans & Rosie M Walker & Mairead L Bermingham & Stewart W Morris & Archie Campbell & Caroline Hayward & Alison D Murray & David J Porteous & Steve Horvath & Ake T Lu & Andrew M McIntosh & Heather C Whalley & Riccardo E Marioni
1-38 Microbial phenotypic heterogeneity in response to a metabolic toxin: Continuous, dynamically shifting distribution of formaldehyde tolerance in Methylobacterium extorquens populations
by Jessica A Lee & Siavash Riazi & Shahla Nemati & Jannell V Bazurto & Andreas E Vasdekis & Benjamin J Ridenhour & Christopher H Remien & Christopher J Marx

October 2019, Volume 15, Issue 10

1-18 Bayesian multivariate reanalysis of large genetic studies identifies many new associations
by Michael C Turchin & Matthew Stephens
1-29 Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells
by Edwige B Garcin & Stéphanie Gon & Meghan R Sullivan & Gregory J Brunette & Anne De Cian & Jean-Paul Concordet & Carine Giovannangeli & Wilhelm G Dirks & Sonja Eberth & Kara A Bernstein & Rohit Prakash & Maria Jasin & Mauro Modesti

September 2019, Volume 15, Issue 9

1-25 The inference of sex-biased human demography from whole-genome data
by Shaila Musharoff & Suyash Shringarpure & Carlos D Bustamante & Sohini Ramachandran
1-32 An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data
by Aaron J Stern & Peter R Wilton & Rasmus Nielsen

July 2019, Volume 15, Issue 7

1-30 Novel protective and risk loci in hip dysplasia in German Shepherds
by Lea I Mikkola & Saila Holopainen & Anu K Lappalainen & Tiina Pessa-Morikawa & Thomas J P Augustine & Meharji Arumilli & Marjo K Hytönen & Osmo Hakosalo & Hannes Lohi & Antti Iivanainen

June 2019, Volume 15, Issue 6

1-19 Host-dependent nitrogen recycling as a mechanism of symbiont control in Aiptasia
by Guoxin Cui & Yi Jin Liew & Yong Li & Najeh Kharbatia & Noura I Zahran & Abdul-Hamid Emwas & Victor M Eguiluz & Manuel Aranda

May 2019, Volume 15, Issue 5

1-22 Estimating variance components in population scale family trees
by Tal Shor & Iris Kalka & Dan Geiger & Yaniv Erlich & Omer Weissbrod

April 2019, Volume 15, Issue 4

1-16 Discovery and characterization of variance QTLs in human induced pluripotent stem cells
by Abhishek K Sarkar & Po-Yuan Tung & John D Blischak & Jonathan E Burnett & Yang I Li & Matthew Stephens & Yoav Gilad
1-18 Genome-wide association study reveals sex-specific genetic architecture of facial attractiveness
by Bowen Hu & Ning Shen & James J Li & Hyunseung Kang & Jinkuk Hong & Jason Fletcher & Jan Greenberg & Marsha R Mailick & Qiongshi Lu
1-18 Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis
by Zhixiu Li & Servet Akar & Handan Yarkan & Sau Kuen Lee & Pınar Çetin & Gerçek Can & Gökce Kenar & Fernur Çapa & Omer Nuri Pamuk & Yavuz Pehlivan & Katie Cremin & Erika De Guzman & Jessica Harris & Lawrie Wheeler & Ahmadreza Jamshidi & Mahdi Vojdanian & Elham Farhadi & Nooshin Ahmadzadeh & Zeynep Yüce & Ediz Dalkılıç & Dilek Solmaz & Berrin Akın & Salim Dönmez & İsmail Sarı & Paul J Leo & Tony J Kenna & Fatos Önen & Mahdi Mahmoudi & Matthew A Brown & Nurullah Akkoc
1-21 FunSPU: A versatile and adaptive multiple functional annotation-based association test of whole-genome sequencing data
by Yiding Ma & Peng Wei
1-31 Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep
by Brian E Cade & Han Chen & Adrienne M Stilp & Tin Louie & Sonia Ancoli-Israel & Raanan Arens & Richard Barfield & Jennifer E Below & Jianwen Cai & Matthew P Conomos & Daniel S Evans & Alexis C Frazier-Wood & Sina A Gharib & Kevin J Gleason & Daniel J Gottlieb & David R Hillman & W Craig Johnson & David J Lederer & Jiwon Lee & Jose S Loredo & Hao Mei & Sutapa Mukherjee & Sanjay R Patel & Wendy S Post & Shaun M Purcell & Alberto R Ramos & Kathryn J Reid & Ken Rice & Neomi A Shah & Tamar Sofer & Kent D Taylor & Timothy A Thornton & Heming Wang & Kristine Yaffe & Phyllis C Zee & Craig L Hanis & Lyle J Palmer & Jerome I Rotter & Katie L Stone & Gregory J Tranah & James G Wilson & Shamil R Sunyaev & Cathy C Laurie & Xiaofeng Zhu & Richa Saxena & Xihong Lin & Susan Redline

March 2019, Volume 15, Issue 3

1-27 Powerful gene set analysis in GWAS with the Generalized Berk-Jones statistic
by Ryan Sun & Shirley Hui & Gary D Bader & Xihong Lin & Peter Kraft

February 2019, Volume 15, Issue 2

1-20 Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization
by Louise A C Millard & Neil M Davies & Kate Tilling & Tom R Gaunt & George Davey Smith
1-24 Fast and flexible linear mixed models for genome-wide genetics
by Daniel E Runcie & Lorin Crawford
1-29 Spatial soft sweeps: Patterns of adaptation in populations with long-range dispersal
by Jayson Paulose & Joachim Hermisson & Oskar Hallatschek
1-31 Transcription-dependent spreading of the Dal80 yeast GATA factor across the body of highly expressed genes
by Aria Ronsmans & Maxime Wery & Ugo Szachnowski & Camille Gautier & Marc Descrimes & Evelyne Dubois & Antonin Morillon & Isabelle Georis
1-33 Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila
by Gabriel E Rech & María Bogaerts-Márquez & Maite G Barrón & Miriam Merenciano & José Luis Villanueva-Cañas & Vivien Horváth & Anna-Sophie Fiston-Lavier & Isabelle Luyten & Sandeep Venkataram & Hadi Quesneville & Dmitri A Petrov & Josefa González

January 2019, Volume 15, Issue 1

1-20 Integrating predicted transcriptome from multiple tissues improves association detection
by Alvaro N Barbeira & Milton Pividori & Jiamao Zheng & Heather E Wheeler & Dan L Nicolae & Hae Kyung Im

December 2018, Volume 14, Issue 12

1-15 Expression reflects population structure
by Brielin C Brown & Nicolas L Bray & Lior Pachter
1-15 Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity
by Shouneng Peng & Maya A Deyssenroth & Antonio F Di Narzo & Haoxiang Cheng & Zhongyang Zhang & Luca Lambertini & Arno Ruusalepp & Jason C Kovacic & Johan L M Bjorkegren & Carmen J Marsit & Jia Chen & Ke Hao
1-20 Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
by Felix Day & Tugce Karaderi & Michelle R Jones & Cindy Meun & Chunyan He & Alex Drong & Peter Kraft & Nan Lin & Hongyan Huang & Linda Broer & Reedik Magi & Richa Saxena & Triin Laisk & Margrit Urbanek & M Geoffrey Hayes & Gudmar Thorleifsson & Juan Fernandez-Tajes & Anubha Mahajan & Benjamin H Mullin & Bronwyn G A Stuckey & Timothy D Spector & Scott G Wilson & Mark O Goodarzi & Lea Davis & Barbara Obermayer-Pietsch & André G Uitterlinden & Verneri Anttila & Benjamin M Neale & Marjo-Riitta Jarvelin & Bart Fauser & Irina Kowalska & Jenny A Visser & Marianne Andersen & Ken Ong & Elisabet Stener-Victorin & David Ehrmann & Richard S Legro & Andres Salumets & Mark I McCarthy & Laure Morin-Papunen & Unnur Thorsteinsdottir & Kari Stefansson & the 23andMe Research Team & Unnur Styrkarsdottir & John R B Perry & Andrea Dunaif & Joop Laven & Steve Franks & Cecilia M Lindgren & Corrine K Welt
1-27 Bayesian multiple logistic regression for case-control GWAS
by Saikat Banerjee & Lingyao Zeng & Heribert Schunkert & Johannes Söding
1-42 Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo
by Quira Zeidan & Feng He & Fan Zhang & Hongen Zhang & Allan Jacobson & Alan G Hinnebusch

November 2018, Volume 14, Issue 11

1-11 How many individuals share a mitochondrial genome?
by Mikkel M Andersen & David J Balding
1-22 Single-cell RNA-sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium
by Nhung H Vuong & David P Cook & Laura A Forrest & Lauren E Carter & Pascale Robineau-Charette & Joshua M Kofsky & Kendra M Hodgkinson & Barbara C Vanderhyden

October 2018, Volume 14, Issue 10

1-14 ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls
by Audrey E Hendricks & Stephen C Billups & Hamish N C Pike & I Sadaf Farooqi & Eleftheria Zeggini & Stephanie A Santorico & Inês Barroso & Josée Dupuis
1-15 Metabolic adaptations underlying genome flexibility in prokaryotes
by Akshit Goyal
1-21 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits
by Guanghao Qi & Nilanjan Chatterjee
1-22 Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia
by William K Scott & Felix Mba Medie & Felicia Ruffin & Batu K Sharma-Kuinkel & Derek D Cyr & Shengru Guo & Derek M Dykxhoorn & Robert L Skov & Niels E Bruun & Anders Dahl & Christian J Lerche & Andreas Petersen & Anders Rhod Larsen & Trine Kiilerich Lauridsen & Helle Krogh Johansen & Henrik Ullum & Erik Sørensen & Christian Hassager & Henning Bundgaard & Henrik C Schønheyder & Christian Torp-Pedersen & Louise Bruun Østergaard & Magnus Arpi & Flemming Rosenvinge & Lise T Erikstrup & Mahtab Chehri & Peter Søgaard & Paal S Andersen & Vance G Fowler Jr.
1-25 A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery
by Patricia D A Rohs & Jackson Buss & Sue I Sim & Georgia R Squyres & Veerasak Srisuknimit & Mandy Smith & Hongbaek Cho & Megan Sjodt & Andrew C Kruse & Ethan C Garner & Suzanne Walker & Daniel E Kahne & Thomas G Bernhardt

September 2018, Volume 14, Issue 9

1-15 Detecting archaic introgression using an unadmixed outgroup
by Laurits Skov & Ruoyun Hui & Vladimir Shchur & Asger Hobolth & Aylwyn Scally & Mikkel Heide Schierup & Richard Durbin
1-23 Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
by Pradeep Suri & Melody R Palmer & Yakov A Tsepilov & Maxim B Freidin & Cindy G Boer & Michelle S Yau & Daniel S Evans & Andrea Gelemanovic & Traci M Bartz & Maria Nethander & Liubov Arbeeva & Lennart Karssen & Tuhina Neogi & Archie Campbell & Dan Mellstrom & Claes Ohlsson & Lynn M Marshall & Eric Orwoll & Andre Uitterlinden & Jerome I Rotter & Gordan Lauc & Bruce M Psaty & Magnus K Karlsson & Nancy E Lane & Gail P Jarvik & Ozren Polasek & Marc Hochberg & Joanne M Jordan & Joyce B J Van Meurs & Rebecca Jackson & Carrie M Nielson & Braxton D Mitchell & Blair H Smith & Caroline Hayward & Nicholas L Smith & Yurii S Aulchenko & Frances M K Williams
1-24 Distinct CED-10/Rac1 domains confer context-specific functions in development
by Steffen Nørgaard & Shuer Deng & Wei Cao & Roger Pocock

August 2018, Volume 14, Issue 8

1-18 Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology
by Laurence J Howe & Myoung Keun Lee & Gemma C Sharp & George Davey Smith & Beate St Pourcain & John R Shaffer & Kerstin U Ludwig & Elisabeth Mangold & Mary L Marazita & Eleanor Feingold & Alexei Zhurov & Evie Stergiakouli & Jonathan Sandy & Stephen Richmond & Seth M Weinberg & Gibran Hemani & Sarah J Lewis
1-19 A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1
by Ying Chen & Melissa A Gilbert & Christopher M Grochowski & Deborah McEldrew & Jessica Llewellyn & Orith Waisbourd-Zinman & Hakon Hakonarson & Joan E Bailey-Wilson & Pierre Russo & Rebecca G Wells & Kathleen M Loomes & Nancy B Spinner & Marcella Devoto
1-21 Genetic architecture of gene expression traits across diverse populations
by Lauren S Mogil & Angela Andaleon & Alexa Badalamenti & Scott P Dickinson & Xiuqing Guo & Jerome I Rotter & W Craig Johnson & Hae Kyung Im & Yongmei Liu & Heather E Wheeler
1-25 Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue
by Oneil G Bhalala & Artika P Nath & UK Brain Expression Consortium & Michael Inouye & Christopher R Sibley

July 2018, Volume 14, Issue 7

1-19 Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes
by Yu Jiang & Sai Chen & Daniel McGuire & Fang Chen & Mengzhen Liu & William G Iacono & John K Hewitt & John E Hokanson & Kenneth Krauter & Markku Laakso & Kevin W Li & Sharon M Lutz & Matthew McGue & Anita Pandit & Gregory J M Zajac & Michael Boehnke & Goncalo R Abecasis & Scott I Vrieze & Xiaowei Zhan & Bibo Jiang & Dajiang J Liu
1-28 Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier
by Nicholas A Willis & Arvind Panday & Erin E Duffey & Ralph Scully

June 2018, Volume 14, Issue 6

1-21 Calcium and cAMP directly modulate the speed of the Drosophila circadian clock
by Angelina Palacios-Muñoz & John Ewer

May 2018, Volume 14, Issue 5

1-20 Machine learning identifies signatures of host adaptation in the bacterial pathogen Salmonella enterica
by Nicole E Wheeler & Paul P Gardner & Lars Barquist

February 2018, Volume 14, Issue 2

1-20 Deep sequencing of HBV pre-S region reveals high heterogeneity of HBV genotypes and associations of word pattern frequencies with HCC
by Xin Bai & Jian-an Jia & Meng Fang & Shipeng Chen & Xiaotao Liang & Shanfeng Zhu & Shuqin Zhang & Jianfeng Feng & Fengzhu Sun & Chunfang Gao
1-25 Methods for fine-mapping with chromatin and expression data
by Megan Roytman & Gleb Kichaev & Alexander Gusev & Bogdan Pasaniuc

January 2018, Volume 14, Issue 1

1-22 Insular Celtic population structure and genomic footprints of migration
by Ross P Byrne & Rui Martiniano & Lara M Cassidy & Matthew Carrigan & Garrett Hellenthal & Orla Hardiman & Daniel G Bradley & Russell L McLaughlin
1-32 Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies
by Xingjie Hao & Ping Zeng & Shujun Zhang & Xiang Zhou

December 2017, Volume 13, Issue 12

1-16 Background sequence characteristics influence the occurrence and severity of disease-causing mtDNA mutations
by Wei Wei & Aurora Gomez-Duran & Gavin Hudson & Patrick F Chinnery

November 2017, Volume 13, Issue 11

1-12 A case-control collapsing analysis identifies epilepsy genes implicated in trio sequencing studies focused on de novo mutations
by Xiaolin Zhu & Raghavendra Padmanabhan & Brett Copeland & Joshua Bridgers & Zhong Ren & Sitharthan Kamalakaran & Ailbhe O'Driscoll-Collins & Samuel F Berkovic & Ingrid E Scheffer & Annapurna Poduri & Davide Mei & Renzo Guerrini & Daniel H Lowenstein & Andrew S Allen & Erin L Heinzen & David B Goldstein
1-22 Orienting the causal relationship between imprecisely measured traits using GWAS summary data
by Gibran Hemani & Kate Tilling & George Davey Smith

September 2017, Volume 13, Issue 9

1-17 Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer
by Guimin Gao & Brandon L Pierce & Olufunmilayo I Olopade & Hae Kyung Im & Dezheng Huo
1-20 Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status
by Mathias Rask-Andersen & Torgny Karlsson & Weronica E Ek & Åsa Johansson
1-21 Incomplete dominance of deleterious alleles contributes substantially to trait variation and heterosis in maize
by Jinliang Yang & Sofiane Mezmouk & Andy Baumgarten & Edward S Buckler & Katherine E Guill & Michael D McMullen & Rita H Mumm & Jeffrey Ross-Ibarra

August 2017, Volume 13, Issue 8

1-16 Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells
by Uri Weissbein & Omer Plotnik & Dan Vershkov & Nissim Benvenisty
1-21 Composite likelihood method for inferring local pedigrees
by Amy Ko & Rasmus Nielsen
1-27 Deconstructing isolation-by-distance: The genomic consequences of limited dispersal
by Stepfanie M Aguillon & John W Fitzpatrick & Reed Bowman & Stephan J Schoech & Andrew G Clark & Graham Coop & Nancy Chen
1-30 Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice
by Ashley Snouffer & Desmond Brown & Hankyu Lee & Jonathon Walsh & Floria Lupu & Ryan Norman & Karl Lechtreck & Hyuk Wan Ko & Jonathan Eggenschwiler

July 2017, Volume 13, Issue 7

1-18 Statistical correction of the Winner’s Curse explains replication variability in quantitative trait genome-wide association studies
by Cameron Palmer & Itsik Pe’er
1-22 African genetic ancestry interacts with body mass index to modify risk for uterine fibroids
by Ayush Giri & Todd L Edwards & Katherine E Hartmann & Eric S Torstenson & Melissa Wellons & Pamela J Schreiner & Digna R Velez Edwards

June 2017, Volume 13, Issue 6

1-15 Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions
by Dmitry Shungin & Wei Q Deng & Tibor V Varga & Jian'an Luan & Evelin Mihailov & Andres Metspalu & GIANT Consortium & Andrew P Morris & Nita G Forouhi & Cecilia Lindgren & Patrik K E Magnusson & Nancy L Pedersen & Göran Hallmans & Audrey Y Chu & Anne E Justice & Mariaelisa Graff & Thomas W Winkler & Lynda M Rose & Claudia Langenberg & L Adrienne Cupples & Paul M Ridker & Nicholas J Wareham & Ken K Ong & Ruth J F Loos & Daniel I Chasman & Erik Ingelsson & Tuomas O Kilpeläinen & Robert A Scott & Reedik Mägi & Guillaume Paré & Paul W Franks
1-22 Joint modeling of genetically correlated diseases and functional annotations increases accuracy of polygenic risk prediction
by Yiming Hu & Qiongshi Lu & Wei Liu & Yuhua Zhang & Mo Li & Hongyu Zhao

May 2017, Volume 13, Issue 5

1-17 Identifying systematic heterogeneity patterns in genetic association meta-analysis studies
by Lerato E Magosi & Anuj Goel & Jemma C Hopewell & Martin Farrall & on behalf of the CARDIoGRAMplusC4D Consortium
1-25 Tandem duplications lead to novel expression patterns through exon shuffling in Drosophila yakuba
by Rebekah L Rogers & Ling Shao & Kevin R Thornton

April 2017, Volume 13, Issue 4

1-22 Structured mating: Patterns and implications
by Ronnie Sebro & Gina M Peloso & Josée Dupuis & Neil J Risch
1-24 The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples
by Signe Penner-Goeke & Zelda Lichtensztejn & Megan Neufeld & Jennifer L Ali & Alon D Altman & Mark W Nachtigal & Kirk J McManus
1-25 Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium
by Maggie C Y Ng & Mariaelisa Graff & Yingchang Lu & Anne E Justice & Poorva Mudgal & Ching-Ti Liu & Kristin Young & Lisa R Yanek & Mary F Feitosa & Mary K Wojczynski & Kristin Rand & Jennifer A Brody & Brian E Cade & Latchezar Dimitrov & Qing Duan & Xiuqing Guo & Leslie A Lange & Michael A Nalls & Hayrettin Okut & Salman M Tajuddin & Bamidele O Tayo & Sailaja Vedantam & Jonathan P Bradfield & Guanjie Chen & Wei-Min Chen & Alessandra Chesi & Marguerite R Irvin & Badri Padhukasahasram & Jennifer A Smith & Wei Zheng & Matthew A Allison & Christine B Ambrosone & Elisa V Bandera & Traci M Bartz & Sonja I Berndt & Leslie Bernstein & William J Blot & Erwin P Bottinger & John Carpten & Stephen J Chanock & Yii-Der Ida Chen & David V Conti & Richard S Cooper & Myriam Fornage & Barry I Freedman & Melissa Garcia & Phyllis J Goodman & Yu-Han H Hsu & Jennifer Hu & Chad D Huff & Sue A Ingles & Esther M John & Rick Kittles & Eric Klein & Jin Li & Barbara McKnight & Uma Nayak & Barbara Nemesure & Adesola Ogunniyi & Andrew Olshan & Michael F Press & Rebecca Rohde & Benjamin A Rybicki & Babatunde Salako & Maureen Sanderson & Yaming Shao & David S Siscovick & Janet L Stanford & Victoria L Stevens & Alex Stram & Sara S Strom & Dhananjay Vaidya & John S Witte & Jie Yao & Xiaofeng Zhu & Regina G Ziegler & Alan B Zonderman & Adebowale Adeyemo & Stefan Ambs & Mary Cushman & Jessica D Faul & Hakon Hakonarson & Albert M Levin & Katherine L Nathanson & Erin B Ware & David R Weir & Wei Zhao & Degui Zhi & The Bone Mineral Density in Childhood Study (BMDCS) Group & Donna K Arnett & Struan F A Grant & Sharon L R Kardia & Olufunmilayo I Oloapde & D C Rao & Charles N Rotimi & Michele M Sale & L Keoki Williams & Babette S Zemel & Diane M Becker & Ingrid B Borecki & Michele K Evans & Tamara B Harris & Joel N Hirschhorn & Yun Li & Sanjay R Patel & Bruce M Psaty & Jerome I Rotter & James G Wilson & Donald W Bowden & L Adrienne Cupples & Christopher A Haiman & Ruth J F Loos & Kari E North
1-26 Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
by Mariaelisa Graff & Robert A Scott & Anne E Justice & Kristin L Young & Mary F Feitosa & Llilda Barata & Thomas W Winkler & Audrey Y Chu & Anubha Mahajan & David Hadley & Luting Xue & Tsegaselassie Workalemahu & Nancy L Heard-Costa & Marcel den Hoed & Tarunveer S Ahluwalia & Qibin Qi & Julius S Ngwa & Frida Renström & Lydia Quaye & John D Eicher & James E Hayes & Marilyn Cornelis & Zoltan Kutalik & Elise Lim & Jian’an Luan & Jennifer E Huffman & Weihua Zhang & Wei Zhao & Paula J Griffin & Toomas Haller & Shafqat Ahmad & Pedro M Marques-Vidal & Stephanie Bien & Loic Yengo & Alexander Teumer & Albert Vernon Smith & Meena Kumari & Marie Neergaard Harder & Johanne Marie Justesen & Marcus E Kleber & Mette Hollensted & Kurt Lohman & Natalia V Rivera & John B Whitfield & Jing Hua Zhao & Heather M Stringham & Leo-Pekka Lyytikäinen & Charlotte Huppertz & Gonneke Willemsen & Wouter J Peyrot & Ying Wu & Kati Kristiansson & Ayse Demirkan & Myriam Fornage & Maija Hassinen & Lawrence F Bielak & Gemma Cadby & Toshiko Tanaka & Reedik Mägi & Peter J van der Most & Anne U Jackson & Jennifer L Bragg-Gresham & Veronique Vitart & Jonathan Marten & Pau Navarro & Claire Bellis & Dorota Pasko & Åsa Johansson & Søren Snitker & Yu-Ching Cheng & Joel Eriksson & Unhee Lim & Mette Aadahl & Linda S Adair & Najaf Amin & Beverley Balkau & Juha Auvinen & John Beilby & Richard N Bergman & Sven Bergmann & Alain G Bertoni & John Blangero & Amélie Bonnefond & Lori L Bonnycastle & Judith B Borja & Søren Brage & Fabio Busonero & Steve Buyske & Harry Campbell & Peter S Chines & Francis S Collins & Tanguy Corre & George Davey Smith & Graciela E Delgado & Nicole Dueker & Marcus Dörr & Tapani Ebeling & Gudny Eiriksdottir & Tõnu Esko & Jessica D Faul & Mao Fu & Kristine Færch & Christian Gieger & Sven Gläser & Jian Gong & Penny Gordon-Larsen & Harald Grallert & Tanja B Grammer & Niels Grarup & Gerard van Grootheest & Kennet Harald & Nicholas D Hastie & Aki S Havulinna & Dena Hernandez & Lucia Hindorff & Lynne J Hocking & Oddgeir L Holmens & Christina Holzapfel & Jouke Jan Hottenga & Jie Huang & Tao Huang & Jennie Hui & Cornelia Huth & Nina Hutri-Kähönen & Alan L James & John-Olov Jansson & Min A Jhun & Markus Juonala & Leena Kinnunen & Heikki A Koistinen & Ivana Kolcic & Pirjo Komulainen & Johanna Kuusisto & Kirsti Kvaløy & Mika Kähönen & Timo A Lakka & Lenore J Launer & Benjamin Lehne & Cecilia M Lindgren & Mattias Lorentzon & Robert Luben & Michel Marre & Yuri Milaneschi & Keri L Monda & Grant W Montgomery & Marleen H M De Moor & Antonella Mulas & Martina Müller-Nurasyid & A W Musk & Reija Männikkö & Satu Männistö & Narisu Narisu & Matthias Nauck & Jennifer A Nettleton & Ilja M Nolte & Albertine J Oldehinkel & Matthias Olden & Ken K Ong & Sandosh Padmanabhan & Lavinia Paternoster & Jeremiah Perez & Markus Perola & Annette Peters & Ulrike Peters & Patricia A Peyser & Inga Prokopenko & Hannu Puolijoki & Olli T Raitakari & Tuomo Rankinen & Laura J Rasmussen-Torvik & Rajesh Rawal & Paul M Ridker & Lynda M Rose & Igor Rudan & Cinzia Sarti & Mark A Sarzynski & Kai Savonen & William R Scott & Serena Sanna & Alan R Shuldiner & Steve Sidney & Günther Silbernagel & Blair H Smith & Jennifer A Smith & Harold Snieder & Alena Stančáková & Barbara Sternfeld & Amy J Swift & Tuija Tammelin & Sian-Tsung Tan & Barbara Thorand & Dorothée Thuillier & Liesbeth Vandenput & Henrik Vestergaard & Jana V van Vliet-Ostaptchouk & Marie-Claude Vohl & Uwe Völker & Gérard Waeber & Mark Walker & Sarah Wild & Andrew Wong & Alan F Wright & M Carola Zillikens & Niha Zubair & Christopher A Haiman & Loic Lemarchand & Ulf Gyllensten & Claes Ohlsson & Albert Hofman & Fernando Rivadeneira & André G Uitterlinden & Louis Pérusse & James F Wilson & Caroline Hayward & Ozren Polasek & Francesco Cucca & Kristian Hveem & Catharina A Hartman & Anke Tönjes & Stefania Bandinelli & Lyle J Palmer & Sharon L R Kardia & Rainer Rauramaa & Thorkild I A Sørensen & Jaakko Tuomilehto & Veikko Salomaa & Brenda W J H Penninx & Eco J C de Geus & Dorret I Boomsma & Terho Lehtimäki & Massimo Mangino & Markku Laakso & Claude Bouchard & Nicholas G Martin & Diana Kuh & Yongmei Liu & Allan Linneberg & Winfried März & Konstantin Strauch & Mika Kivimäki & Tamara B Harris & Vilmundur Gudnason & Henry Völzke & Lu Qi & Marjo-Riitta Järvelin & John C Chambers & Jaspal S Kooner & Philippe Froguel & Charles Kooperberg & Peter Vollenweider & Göran Hallmans & Torben Hansen & Oluf Pedersen & Andres Metspalu & Nicholas J Wareham & Claudia Langenberg & David R Weir & David J Porteous & Eric Boerwinkle & Daniel I Chasman & CHARGE Consortium & EPIC-InterAct Consortium & PAGE Consortium & Gonçalo R Abecasis & Inês Barroso & Mark I McCarthy & Timothy M Frayling & Jeffrey R O’Connell & Cornelia M van Duijn & Michael Boehnke & Iris M Heid & Karen L Mohlke & David P Strachan & Caroline S Fox & Ching-Ti Liu & Joel N Hirschhorn & Robert J Klein & Andrew D Johnson & Ingrid B Borecki & Paul W Franks & Kari E North & L Adrienne Cupples & Ruth J F Loos & Tuomas O Kilpeläinen
1-27 Joint genetic analysis using variant sets reveals polygenic gene-context interactions
by Francesco Paolo Casale & Danilo Horta & Barbara Rakitsch & Oliver Stegle

March 2017, Volume 13, Issue 3

1-23 Visualizing the structure of RNA-seq expression data using grade of membership models
by Kushal K Dey & Chiaowen Joyce Hsiao & Matthew Stephens
1-25 Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data
by Takashi Nozoe & Edo Kussell & Yuichi Wakamoto
1-25 Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization
by Xiaoquan Wen & Roger Pique-Regi & Francesca Luca

February 2017, Volume 13, Issue 2

1-16 A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy
by Vinicius M Fava & Jeremy Manry & Aurélie Cobat & Marianna Orlova & Nguyen Van Thuc & Milton O Moraes & Carolinne Sales-Marques & Mariane M A Stefani & Ana Carla P Latini & Andrea F Belone & Vu Hong Thai & Laurent Abel & Alexandre Alcaïs & Erwin Schurr
1-22 GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway
by Krzysztof Kiryluk & Yifu Li & Zina Moldoveanu & Hitoshi Suzuki & Colin Reily & Ping Hou & Jingyuan Xie & Nikol Mladkova & Sindhuri Prakash & Clara Fischman & Samantha Shapiro & Robert A LeDesma & Drew Bradbury & Iuliana Ionita-Laza & Frank Eitner & Thomas Rauen & Nicolas Maillard & Francois Berthoux & Jürgen Floege & Nan Chen & Hong Zhang & Francesco Scolari & Robert J Wyatt & Bruce A Julian & Ali G Gharavi & Jan Novak

January 2017, Volume 13, Issue 1

1-17 The Replisomes Remain Spatially Proximal throughout the Cell Cycle in Bacteria
by Sarah M Mangiameli & Brian T Veit & Houra Merrikh & Paul A Wiggins
1-23 Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies
by Ronald de Vlaming & Aysu Okbay & Cornelius A Rietveld & Magnus Johannesson & Patrik K E Magnusson & André G Uitterlinden & Frank J A van Rooij & Albert Hofman & Patrick J F Groenen & A Roy Thurik & Philipp D Koellinger
1-25 Genetic Variation in the Social Environment Contributes to Health and Disease
by Amelie Baud & Megan K Mulligan & Francesco Paolo Casale & Jesse F Ingels & Casey J Bohl & Jacques Callebert & Jean-Marie Launay & Jon Krohn & Andres Legarra & Robert W Williams & Oliver Stegle
1-40 A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy
by Russell Corbett-Detig & Rasmus Nielsen

December 2016, Volume 12, Issue 12

1-6 Deep Reads: Favorites from a Few Different Shelves
by Bruce A Hamilton
1-24 Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data
by Jianxin Shi & Ju-Hyun Park & Jubao Duan & Sonja T Berndt & Winton Moy & Kai Yu & Lei Song & William Wheeler & Xing Hua & Debra Silverman & Montserrat Garcia-Closas & Chao Agnes Hsiung & Jonine D Figueroa & Victoria K Cortessis & Núria Malats & Margaret R Karagas & Paolo Vineis & I-Shou Chang & Dongxin Lin & Baosen Zhou & Adeline Seow & Keitaro Matsuo & Yun-Chul Hong & Neil E Caporaso & Brian Wolpin & Eric Jacobs & Gloria M Petersen & Alison P Klein & Donghui Li & Harvey Risch & Alan R Sanders & Li Hsu & Robert E Schoen & Hermann Brenner & MGS (Molecular Genetics of Schizophrenia) GWAS Consortium & GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium) & The GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium & PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium & PanScan Consortium & The GAME-ON/ELLIPSE Consortium & Rachael Stolzenberg-Solomon & Pablo Gejman & Qing Lan & Nathaniel Rothman & Laufey T Amundadottir & Maria Teresa Landi & Douglas F Levinson & Stephen J Chanock & Nilanjan Chatterjee

November 2016, Volume 12, Issue 11

1-23 Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues
by Heather E Wheeler & Kaanan P Shah & Jonathon Brenner & Tzintzuni Garcia & Keston Aquino-Michaels & GTEx Consortium & Nancy J Cox & Dan L Nicolae & Hae Kyung Im

October 2016, Volume 12, Issue 10

1-20 A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records
by Thomas J Hoffmann & Bronya J Keats & Noriko Yoshikawa & Catherine Schaefer & Neil Risch & Lawrence R Lustig
1-28 CERAMIC: Case-Control Association Testing in Samples with Related Individuals, Based on Retrospective Mixed Model Analysis with Adjustment for Covariates
by Sheng Zhong & Duo Jiang & Mary Sara McPeek

September 2016, Volume 12, Issue 9

1-19 Using Genetic Distance to Infer the Accuracy of Genomic Prediction
by Marco Scutari & Ian Mackay & David Balding
1-24 The Impact of Endurance Training on Human Skeletal Muscle Memory, Global Isoform Expression and Novel Transcripts
by Maléne E Lindholm & Stefania Giacomello & Beata Werne Solnestam & Helene Fischer & Mikael Huss & Sanela Kjellqvist & Carl Johan Sundberg
1-24 Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy
by Stacey D Wagner & Adam J Struck & Riti Gupta & Dylan R Farnsworth & Amy E Mahady & Katy Eichinger & Charles A Thornton & Eric T Wang & J Andrew Berglund

August 2016, Volume 12, Issue 8

1-19 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci
by Samuel E Jones & Jessica Tyrrell & Andrew R Wood & Robin N Beaumont & Katherine S Ruth & Marcus A Tuke & Hanieh Yaghootkar & Youna Hu & Maris Teder-Laving & Caroline Hayward & Till Roenneberg & James F Wilson & Fabiola Del Greco & Andrew A Hicks & Chol Shin & Chang-Ho Yun & Seung Ku Lee & Andres Metspalu & Enda M Byrne & Philip R Gehrman & Henning Tiemeier & Karla V Allebrandt & Rachel M Freathy & Anna Murray & David A Hinds & Timothy M Frayling & Michael N Weedon
1-19 Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape
by Joanne B Cole & Mange Manyama & Emmanuel Kimwaga & Joshua Mathayo & Jacinda R Larson & Denise K Liberton & Ken Lukowiak & Tracey M Ferrara & Sheri L Riccardi & Mao Li & Washington Mio & Michaela Prochazkova & Trevor Williams & Hong Li & Kenneth L Jones & Ophir D Klein & Stephanie A Santorico & Benedikt Hallgrimsson & Richard A Spritz
1-21 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology
by John R Shaffer & Ekaterina Orlova & Myoung Keun Lee & Elizabeth J Leslie & Zachary D Raffensperger & Carrie L Heike & Michael L Cunningham & Jacqueline T Hecht & Chung How Kau & Nichole L Nidey & Lina M Moreno & George L Wehby & Jeffrey C Murray & Cecelia A Laurie & Cathy C Laurie & Joanne Cole & Tracey Ferrara & Stephanie Santorico & Ophir Klein & Washington Mio & Eleanor Feingold & Benedikt Hallgrimsson & Richard A Spritz & Mary L Marazita & Seth M Weinberg
1-33 Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD
by Wei Sun & Katerina Kechris & Sean Jacobson & M Bradley Drummond & Gregory A Hawkins & Jenny Yang & Ting-huei Chen & Pedro Miguel Quibrera & Wayne Anderson & R Graham Barr & Patricia V Basta & Eugene R Bleecker & Terri Beaty & Richard Casaburi & Peter Castaldi & Michael H Cho & Alejandro Comellas & James D Crapo & Gerard Criner & Dawn Demeo & Stephanie A Christenson & David J Couper & Jeffrey L Curtis & Claire M Doerschuk & Christine M Freeman & Natalia A Gouskova & MeiLan K Han & Nicola A Hanania & Nadia N Hansel & Craig P Hersh & Eric A Hoffman & Robert J Kaner & Richard E Kanner & Eric C Kleerup & Sharon Lutz & Fernando J Martinez & Deborah A Meyers & Stephen P Peters & Elizabeth A Regan & Stephen I Rennard & Mary Beth Scholand & Edwin K Silverman & Prescott G Woodruff & Wanda K O’Neal & Russell P Bowler & SPIROMICS Research Group & COPDGene Investigators

June 2016, Volume 12, Issue 6

1-17 Bias Characterization in Probabilistic Genotype Data and Improved Signal Detection with Multiple Imputation
by Cameron Palmer & Itsik Pe’er
1-27 Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making
by Pierre Thouvenot & Barbara Ben Yamin & Lou Fourrière & Aurianne Lescure & Thomas Boudier & Elaine Del Nery & Anne Chauchereau & David E Goldgar & Claude Houdayer & Dominique Stoppa-Lyonnet & Alain Nicolas & Gaël A Millot
1-28 A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations
by Han Zhang & William Wheeler & Paula L Hyland & Yifan Yang & Jianxin Shi & Nilanjan Chatterjee & Kai Yu

May 2016, Volume 12, Issue 5

1-19 Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls
by Yi-Juan Hu & Peizhou Liao & H Richard Johnston & Andrew S Allen & Glen A Satten
1-20 A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior
by Anne-Lyse Denizot & Vanessa Besson & Rosa Maria Correra & Alessia Mazzola & Izolina Lopes & Jean-Remy Courbard & Giovanna Marazzi & David A Sassoon

April 2016, Volume 12, Issue 4

1-12 The Increasing Importance of Gene-Based Analyses
by Elizabeth T Cirulli
1-26 Functional Regression Models for Epistasis Analysis of Multiple Quantitative Traits
by Futao Zhang & Dan Xie & Meimei Liang & Momiao Xiong

March 2016, Volume 12, Issue 3

1-19 Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models
by Jae Hoon Sul & Michael Bilow & Wen-Yun Yang & Emrah Kostem & Nick Furlotte & Dan He & Eleazar Eskin
1-21 Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number
by Manja Wachsmuth & Alexander Hübner & Mingkun Li & Burkhard Madea & Mark Stoneking
1-21 Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative Gene
by Kerstin U Ludwig & Syeda Tasnim Ahmed & Anne C Böhmer & Nasim Bahram Sangani & Sheryil Varghese & Johanna Klamt & Hannah Schuenke & Pinar Gültepe & Andrea Hofmann & Michele Rubini & Khalid Ahmed Aldhorae & Regine P Steegers-Theunissen & Augusto Rojas-Martinez & Rudolf Reiter & Guntram Borck & Michael Knapp & Mitsushiro Nakatomi & Daniel Graf & Elisabeth Mangold & Heiko Peters

February 2016, Volume 12, Issue 2

1-23 Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies
by Seung Hoan Choi & Daniela Ruggiero & Rossella Sorice & Ci Song & Teresa Nutile & Albert Vernon Smith & Maria Pina Concas & Michela Traglia & Caterina Barbieri & Ndeye Coumba Ndiaye & Maria G Stathopoulou & Vasiliki Lagou & Giovanni Battista Maestrale & Cinzia Sala & Stephanie Debette & Peter Kovacs & Lars Lind & John Lamont & Peter Fitzgerald & Anke Tönjes & Vilmundur Gudnason & Daniela Toniolo & Mario Pirastu & Celine Bellenguez & Ramachandran S Vasan & Erik Ingelsson & Anne-Louise Leutenegger & Andrew D Johnson & Anita L DeStefano & Sophie Visvikis-Siest & Sudha Seshadri & Marina Ciullo
1-24 Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies
by Xiaolei Liu & Meng Huang & Bin Fan & Edward S Buckler & Zhiwu Zhang

January 2016, Volume 12, Issue 1

1-38 A Spatial Framework for Understanding Population Structure and Admixture
by Gideon S Bradburd & Peter L Ralph & Graham M Coop

December 2015, Volume 11, Issue 12

1-6 Women Who Don't Give a Crap
by Holly Tabor
1-21 An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
by Wesley K Thompson & Yunpeng Wang & Andrew J Schork & Aree Witoelar & Verena Zuber & Shujing Xu & Thomas Werge & Dominic Holland & Schizophrenia Working Group of the Psychiatric Genomics Consortium & Ole A Andreassen & Anders M Dale
1-22 Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer
by Silvia Pineda & Francisco X Real & Manolis Kogevinas & Alfredo Carrato & Stephen J Chanock & Núria Malats & Kristel Van Steen
1-23 Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity
by Kristen Fortney & Edgar Dobriban & Paolo Garagnani & Chiara Pirazzini & Daniela Monti & Daniela Mari & Gil Atzmon & Nir Barzilai & Claudio Franceschi & Art B Owen & Stuart K Kim
1-26 Genomic Insights into the Ancestry and Demographic History of South America
by Julian R Homburger & Andrés Moreno-Estrada & Christopher R Gignoux & Dominic Nelson & Elena Sanchez & Patricia Ortiz-Tello & Bernardo A Pons-Estel & Eduardo Acevedo-Vasquez & Pedro Miranda & Carl D Langefeld & Simon Gravel & Marta E Alarcón-Riquelme & Carlos D Bustamante
1-27 Estimating Information Processing in a Memory System: The Utility of Meta-analytic Methods for Genetics
by Tugce Yildizoglu & Jan-Marek Weislogel & Farhan Mohammad & Edwin S-Y Chan & Pryseley N Assam & Adam Claridge-Chang

November 2015, Volume 11, Issue 11

1-3 Ernst Rüdin and the State of Science
by Michael Yudell

October 2015, Volume 11, Issue 10

1-6 A Decad(e) of Reasons to Contribute to a PLOS Community-Run Journal
by Gregory P Copenhaver & Gregory S Barsh
1-9 Your Data to Explore: An Interview with Anne Wojcicki
by Jane Gitschier
1-17 A Phenomic Scan of the Norfolk Island Genetic Isolate Identifies a Major Pleiotropic Effect Locus Associated with Metabolic and Renal Disorder Markers
by Miles C Benton & Rodney A Lea & Donia Macartney-Coxson & Michelle Hanna & David A Eccles & Melanie A Carless & Geoffrey K Chambers & Claire Bellis & Harald H Goring & Joanne E Curran & Jacquie L Harper & Gregory Gibson & John Blangero & Lyn R Griffiths
1-23 Genome-Wide Association Analysis of Adaptation Using Environmentally Predicted Traits
by Joost van Heerwaarden & Martijn van Zanten & Willem Kruijer
1-42 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
by Thomas W Winkler & Anne E Justice & Mariaelisa Graff & Llilda Barata & Mary F Feitosa & Su Chu & Jacek Czajkowski & Tõnu Esko & Tove Fall & Tuomas O Kilpeläinen & Yingchang Lu & Reedik Mägi & Evelin Mihailov & Tune H Pers & Sina Rüeger & Alexander Teumer & Georg B Ehret & Teresa Ferreira & Nancy L Heard-Costa & Juha Karjalainen & Vasiliki Lagou & Anubha Mahajan & Michael D Neinast & Inga Prokopenko & Jeannette Simino & Tanya M Teslovich & Rick Jansen & Harm-Jan Westra & Charles C White & Devin Absher & Tarunveer S Ahluwalia & Shafqat Ahmad & Eva Albrecht & Alexessander Couto Alves & Jennifer L Bragg-Gresham & Anton J M de Craen & Joshua C Bis & Amélie Bonnefond & Gabrielle Boucher & Gemma Cadby & Yu-Ching Cheng & Charleston W K Chiang & Graciela Delgado & Ayse Demirkan & Nicole Dueker & Niina Eklund & Gudny Eiriksdottir & Joel Eriksson & Bjarke Feenstra & Krista Fischer & Francesca Frau & Tessel E Galesloot & Frank Geller & Anuj Goel & Mathias Gorski & Tanja B Grammer & Stefan Gustafsson & Saskia Haitjema & Jouke-Jan Hottenga & Jennifer E Huffman & Anne U Jackson & Kevin B Jacobs & Åsa Johansson & Marika Kaakinen & Marcus E Kleber & Jari Lahti & Irene Mateo Leach & Benjamin Lehne & Youfang Liu & Ken Sin Lo & Mattias Lorentzon & Jian'an Luan & Pamela A F Madden & Massimo Mangino & Barbara McKnight & Carolina Medina-Gomez & Keri L Monda & May E Montasser & Gabriele Müller & Martina Müller-Nurasyid & Ilja M Nolte & Kalliope Panoutsopoulou & Laura Pascoe & Lavinia Paternoster & Nigel W Rayner & Frida Renström & Federica Rizzi & Lynda M Rose & Kathy A Ryan & Perttu Salo & Serena Sanna & Hubert Scharnagl & Jianxin Shi & Albert Vernon Smith & Lorraine Southam & Alena Stančáková & Valgerdur Steinthorsdottir & Rona J Strawbridge & Yun Ju Sung & Ioanna Tachmazidou & Toshiko Tanaka & Gudmar Thorleifsson & Stella Trompet & Natalia Pervjakova & Jonathan P Tyrer & Liesbeth Vandenput & Sander W van der Laan & Nathalie van der Velde & Jessica van Setten & Jana V van Vliet-Ostaptchouk & Niek Verweij & Efthymia Vlachopoulou & Lindsay L Waite & Sophie R Wang & Zhaoming Wang & Sarah H Wild & Christina Willenborg & James F Wilson & Andrew Wong & Jian Yang & Loïc Yengo & Laura M Yerges-Armstrong & Lei Yu & Weihua Zhang & Jing Hua Zhao & Ehm A Andersson & Stephan J L Bakker & Damiano Baldassarre & Karina Banasik & Matteo Barcella & Cristina Barlassina & Claire Bellis & Paola Benaglio & John Blangero & Matthias Blüher & Fabrice Bonnet & Lori L Bonnycastle & Heather A Boyd & Marcel Bruinenberg & Aron S Buchman & Harry Campbell & Yii-Der Ida Chen & Peter S Chines & Simone Claudi-Boehm & John Cole & Francis S Collins & Eco J C de Geus & Lisette C P G M de Groot & Maria Dimitriou & Jubao Duan & Stefan Enroth & Elodie Eury & Aliki-Eleni Farmaki & Nita G Forouhi & Nele Friedrich & Pablo V Gejman & Bruna Gigante & Nicola Glorioso & Alan S Go & Omri Gottesman & Jürgen Gräßler & Harald Grallert & Niels Grarup & Yu-Mei Gu & Linda Broer & Annelies C Ham & Torben Hansen & Tamara B Harris & Catharina A Hartman & Maija Hassinen & Nicholas Hastie & Andrew T Hattersley & Andrew C Heath & Anjali K Henders & Dena Hernandez & Hans Hillege & Oddgeir Holmen & Kees G Hovingh & Jennie Hui & Lise L Husemoen & Nina Hutri-Kähönen & Pirro G Hysi & Thomas Illig & Philip L De Jager & Shapour Jalilzadeh & Torben Jørgensen & J Wouter Jukema & Markus Juonala & Stavroula Kanoni & Maria Karaleftheri & Kay Tee Khaw & Leena Kinnunen & Steven J Kittner & Wolfgang Koenig & Ivana Kolcic & Peter Kovacs & Nikolaj T Krarup & Wolfgang Kratzer & Janine Krüger & Diana Kuh & Meena Kumari & Theodosios Kyriakou & Claudia Langenberg & Lars Lannfelt & Chiara Lanzani & Vaneet Lotay & Lenore J Launer & Karin Leander & Jaana Lindström & Allan Linneberg & Yan-Ping Liu & Stéphane Lobbens & Robert Luben & Valeriya Lyssenko & Satu Männistö & Patrik K Magnusson & Wendy L McArdle & Cristina Menni & Sigrun Merger & Lili Milani & Grant W Montgomery & Andrew P Morris & Narisu Narisu & Mari Nelis & Ken K Ong & Aarno Palotie & Louis Pérusse & Irene Pichler & Maria G Pilia & Anneli Pouta & Myriam Rheinberger & Rasmus Ribel-Madsen & Marcus Richards & Kenneth M Rice & Treva K Rice & Carlo Rivolta & Veikko Salomaa & Alan R Sanders & Mark A Sarzynski & Salome Scholtens & Robert A Scott & William R Scott & Sylvain Sebert & Sebanti Sengupta & Bengt Sennblad & Thomas Seufferlein & Angela Silveira & P Eline Slagboom & Jan H Smit & Thomas H Sparsø & Kathleen Stirrups & Ronald P Stolk & Heather M Stringham & Morris A Swertz & Amy J Swift & Ann-Christine Syvänen & Sian-Tsung Tan & Barbara Thorand & Anke Tönjes & Angelo Tremblay & Emmanouil Tsafantakis & Peter J van der Most & Uwe Völker & Marie-Claude Vohl & Judith M Vonk & Melanie Waldenberger & Ryan W Walker & Roman Wennauer & Elisabeth Widén & Gonneke Willemsen & Tom Wilsgaard & Alan F Wright & M Carola Zillikens & Suzanne C van Dijk & Natasja M van Schoor & Folkert W Asselbergs & Paul I W de Bakker & Jacques S Beckmann & John Beilby & David A Bennett & Richard N Bergman & Sven Bergmann & Carsten A Böger & Bernhard O Boehm & Eric Boerwinkle & Dorret I Boomsma & Stefan R Bornstein & Erwin P Bottinger & Claude Bouchard & John C Chambers & Stephen J Chanock & Daniel I Chasman & Francesco Cucca & Daniele Cusi & George Dedoussis & Jeanette Erdmann & Johan G Eriksson & Denis A Evans & Ulf de Faire & Martin Farrall & Luigi Ferrucci & Ian Ford & Lude Franke & Paul W Franks & Philippe Froguel & Ron T Gansevoort & Christian Gieger & Henrik Grönberg & Vilmundur Gudnason & Ulf Gyllensten & Per Hall & Anders Hamsten & Pim van der Harst & Caroline Hayward & Markku Heliövaara & Christian Hengstenberg & Andrew A Hicks & Aroon Hingorani & Albert Hofman & Frank Hu & Heikki V Huikuri & Kristian Hveem & Alan L James & Joanne M Jordan & Antti Jula & Mika Kähönen & Eero Kajantie & Sekar Kathiresan & Lambertus A L M Kiemeney & Mika Kivimaki & Paul B Knekt & Heikki A Koistinen & Jaspal S Kooner & Seppo Koskinen & Johanna Kuusisto & Winfried Maerz & Nicholas G Martin & Markku Laakso & Timo A Lakka & Terho Lehtimäki & Guillaume Lettre & Douglas F Levinson & Lars Lind & Marja-Liisa Lokki & Pekka Mäntyselkä & Mads Melbye & Andres Metspalu & Braxton D Mitchell & Frans L Moll & Jeffrey C Murray & Arthur W Musk & Markku S Nieminen & Inger Njølstad & Claes Ohlsson & Albertine J Oldehinkel & Ben A Oostra & Lyle J Palmer & James S Pankow & Gerard Pasterkamp & Nancy L Pedersen & Oluf Pedersen & Brenda W Penninx & Markus Perola & Annette Peters & Ozren Polašek & Peter P Pramstaller & Bruce M Psaty & Lu Qi & Thomas Quertermous & Olli T Raitakari & Tuomo Rankinen & Rainer Rauramaa & Paul M Ridker & John D Rioux & Fernando Rivadeneira & Jerome I Rotter & Igor Rudan & Hester M den Ruijter & Juha Saltevo & Naveed Sattar & Heribert Schunkert & Peter E H Schwarz & Alan R Shuldiner & Juha Sinisalo & Harold Snieder & Thorkild I A Sørensen & Tim D Spector & Jan A Staessen & Bandinelli Stefania & Unnur Thorsteinsdottir & Michael Stumvoll & Jean-Claude Tardif & Elena Tremoli & Jaakko Tuomilehto & André G Uitterlinden & Matti Uusitupa & André L M Verbeek & Sita H Vermeulen & Jorma S Viikari & Veronique Vitart & Henry Völzke & Peter Vollenweider & Gérard Waeber & Mark Walker & Henri Wallaschofski & Nicholas J Wareham & Hugh Watkins & Eleftheria Zeggini & CHARGE Consortium & DIAGRAM Consortium & GLGC Consortium & Global-BPGen Consortium & ICBP Consortium & MAGIC Consortium & Aravinda Chakravarti & Deborah J Clegg & L Adrienne Cupples & Penny Gordon-Larsen & Cashell E Jaquish & D C Rao & Goncalo R Abecasis & Themistocles L Assimes & Inês Barroso & Sonja I Berndt & Michael Boehnke & Panos Deloukas & Caroline S Fox & Leif C Groop & David J Hunter & Erik Ingelsson & Robert C Kaplan & Mark I McCarthy & Karen L Mohlke & Jeffrey R O'Connell & David Schlessinger & David P Strachan & Kari Stefansson & Cornelia M van Duijn & Joel N Hirschhorn & Cecilia M Lindgren & Iris M Heid & Kari E North & Ingrid B Borecki & Zoltán Kutalik & Ruth J F Loos

September 2015, Volume 11, Issue 9

1-14 Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci
by Martijn van de Bunt & Adrian Cortes & IGAS Consortium & Matthew A Brown & Andrew P Morris & Mark I McCarthy
1-23 A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism
by Anu Loukola & Jadwiga Buchwald & Richa Gupta & Teemu Palviainen & Jenni Hällfors & Emmi Tikkanen & Tellervo Korhonen & Miina Ollikainen & Antti-Pekka Sarin & Samuli Ripatti & Terho Lehtimäki & Olli Raitakari & Veikko Salomaa & Richard J Rose & Rachel F Tyndale & Jaakko Kaprio
1-24 Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests
by Mattias Frånberg & Karl Gertow & Anders Hamsten & PROCARDIS consortium & Jens Lagergren & Bengt Sennblad

August 2015, Volume 11, Issue 8

1-19 Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)
by Sudha K Iyengar & John R Sedor & Barry I Freedman & W H Linda Kao & Matthias Kretzler & Benjamin J Keller & Hanna E Abboud & Sharon G Adler & Lyle G Best & Donald W Bowden & Allison Burlock & Yii-Der Ida Chen & Shelley A Cole & Mary E Comeau & Jeffrey M Curtis & Jasmin Divers & Christiane Drechsler & Ravi Duggirala & Robert C Elston & Xiuqing Guo & Huateng Huang & Michael Marcus Hoffmann & Barbara V Howard & Eli Ipp & Paul L Kimmel & Michael J Klag & William C Knowler & Orly F Kohn & Tennille S Leak & David J Leehey & Man Li & Alka Malhotra & Winfried März & Viji Nair & Robert G Nelson & Susanne B Nicholas & Stephen J O’Brien & Madeleine V Pahl & Rulan S Parekh & Marcus G Pezzolesi & Rebekah S Rasooly & Charles N Rotimi & Jerome I Rotter & Jeffrey R Schelling & Michael F Seldin & Vallabh O Shah & Adam M Smiles & Michael W Smith & Kent D Taylor & Farook Thameem & Denyse P Thornley-Brown & Barbara J Truitt & Christoph Wanner & E Jennifer Weil & Cheryl A Winkler & Philip G Zager & Robert P Igo Jr & Robert L Hanson & Carl D Langefeld & Family Investigation of Nephropathy and Diabetes (FIND)
1-22 New Routes to Phylogeography: A Bayesian Structured Coalescent Approximation
by Nicola De Maio & Chieh-Hsi Wu & Kathleen M O’Reilly & Daniel Wilson
1-30 Regulation of Mutagenic DNA Polymerase V Activation in Space and Time
by Andrew Robinson & John P McDonald & Victor E A Caldas & Meghna Patel & Elizabeth A Wood & Christiaan M Punter & Harshad Ghodke & Michael M Cox & Roger Woodgate & Myron F Goodman & Antoine M van Oijen

July 2015, Volume 11, Issue 7

1-24 Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation
by Momoko Horikoshi & Reedik Mӓgi & Martijn van de Bunt & Ida Surakka & Antti-Pekka Sarin & Anubha Mahajan & Letizia Marullo & Gudmar Thorleifsson & Sara Hӓgg & Jouke-Jan Hottenga & Claes Ladenvall & Janina S Ried & Thomas W Winkler & Sara M Willems & Natalia Pervjakova & Tõnu Esko & Marian Beekman & Christopher P Nelson & Christina Willenborg & Steven Wiltshire & Teresa Ferreira & Juan Fernandez & Kyle J Gaulton & Valgerdur Steinthorsdottir & Anders Hamsten & Patrik K E Magnusson & Gonneke Willemsen & Yuri Milaneschi & Neil R Robertson & Christopher J Groves & Amanda J Bennett & Terho Lehtimӓki & Jorma S Viikari & Johan Rung & Valeriya Lyssenko & Markus Perola & Iris M Heid & Christian Herder & Harald Grallert & Martina Müller-Nurasyid & Michael Roden & Elina Hypponen & Aaron Isaacs & Elisabeth M van Leeuwen & Lennart C Karssen & Evelin Mihailov & Jeanine J Houwing-Duistermaat & Anton J M de Craen & Joris Deelen & Aki S Havulinna & Matthew Blades & Christian Hengstenberg & Jeanette Erdmann & Heribert Schunkert & Jaakko Kaprio & Martin D Tobin & Nilesh J Samani & Lars Lind & Veikko Salomaa & Cecilia M Lindgren & P Eline Slagboom & Andres Metspalu & Cornelia M van Duijn & Johan G Eriksson & Annette Peters & Christian Gieger & Antti Jula & Leif Groop & Olli T Raitakari & Chris Power & Brenda W J H Penninx & Eco de Geus & Johannes H Smit & Dorret I Boomsma & Nancy L Pedersen & Erik Ingelsson & Unnur Thorsteinsdottir & Kari Stefansson & Samuli Ripatti & Inga Prokopenko & Mark I McCarthy & Andrew P Morris & ENGAGE Consortium

June 2015, Volume 11, Issue 6

1-19 Leveraging Identity-by-Descent for Accurate Genotype Inference in Family Sequencing Data
by Bingshan Li & Qiang Wei & Xiaowei Zhan & Xue Zhong & Wei Chen & Chun Li & Jonathan Haines

May 2015, Volume 11, Issue 5

1-9 The Whole of a Scientific Career: An Interview with Oliver Smithies
by Jane Gitschier
1-12 Triglyceride-Increasing Alleles Associated with Protection against Type-2 Diabetes
by Yann C Klimentidis & Akshay Chougule & Amit Arora & Alexis C Frazier-Wood & Chiu-Hsieh Hsu
1-17 Cell Specific eQTL Analysis without Sorting Cells
by Harm-Jan Westra & Danny Arends & Tõnu Esko & Marjolein J Peters & Claudia Schurmann & Katharina Schramm & Johannes Kettunen & Hanieh Yaghootkar & Benjamin P Fairfax & Anand Kumar Andiappan & Yang Li & Jingyuan Fu & Juha Karjalainen & Mathieu Platteel & Marijn Visschedijk & Rinse K Weersma & Silva Kasela & Lili Milani & Liina Tserel & Pärt Peterson & Eva Reinmaa & Albert Hofman & André G Uitterlinden & Fernando Rivadeneira & Georg Homuth & Astrid Petersmann & Roberto Lorbeer & Holger Prokisch & Thomas Meitinger & Christian Herder & Michael Roden & Harald Grallert & Samuli Ripatti & Markus Perola & Andrew R Wood & David Melzer & Luigi Ferrucci & Andrew B Singleton & Dena G Hernandez & Julian C Knight & Rossella Melchiotti & Bernett Lee & Michael Poidinger & Francesca Zolezzi & Anis Larbi & De Yun Wang & Leonard H van den Berg & Jan H Veldink & Olaf Rotzschke & Seiko Makino & Veikko Salomaa & Konstantin Strauch & Uwe Völker & Joyce B J van Meurs & Andres Metspalu & Cisca Wijmenga & Ritsert C Jansen & Lude Franke
1-32 Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast
by Gábor Csárdi & Alexander Franks & David S Choi & Edoardo M Airoldi & D Allan Drummond

April 2015, Volume 11, Issue 4

1-21 Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments
by Laura Corrales-Guerrero & Asaf Tal & Rinat Arbel-Goren & Vicente Mariscal & Enrique Flores & Antonia Herrero & Joel Stavans
1-22 Simultaneous Discovery, Estimation and Prediction Analysis of Complex Traits Using a Bayesian Mixture Model
by Gerhard Moser & Sang Hong Lee & Ben J Hayes & Michael E Goddard & Naomi R Wray & Peter M Visscher
1-29 Cross-Population Joint Analysis of eQTLs: Fine Mapping and Functional Annotation
by Xiaoquan Wen & Francesca Luca & Roger Pique-Regi
1-29 Multi-locus Analysis of Genomic Time Series Data from Experimental Evolution
by Jonathan Terhorst & Christian Schlötterer & Yun S Song

March 2015, Volume 11, Issue 3

1-13 Genome-wide Association Study and Meta-Analysis Identify ISL1 as Genome-wide Significant Susceptibility Gene for Bladder Exstrophy
by Markus Draaken & Michael Knapp & Tracie Pennimpede & Johanna M Schmidt & Anne-Karolin Ebert & Wolfgang Rösch & Raimund Stein & Boris Utsch & Karin Hirsch & Thomas M Boemers & Elisabeth Mangold & Stefanie Heilmann & Kerstin U Ludwig & Ekkehart Jenetzky & Nadine Zwink & Susanne Moebus & Bernhard G Herrmann & Manuel Mattheisen & Markus M Nöthen & Michael Ludwig & Heiko Reutter
1-21 Selective and Genetic Constraints on Pneumococcal Serotype Switching
by Nicholas J Croucher & Lisa Kagedan & Claudette M Thompson & Julian Parkhill & Stephen D Bentley & Jonathan A Finkelstein & Marc Lipsitch & William P Hanage

February 2015, Volume 11, Issue 2

1-25 Genomic Selection and Association Mapping in Rice (Oryza sativa): Effect of Trait Genetic Architecture, Training Population Composition, Marker Number and Statistical Model on Accuracy of Rice Genomic Selection in Elite, Tropical Rice Breeding Lines
by Jennifer Spindel & Hasina Begum & Deniz Akdemir & Parminder Virk & Bertrand Collard & Edilberto Redoña & Gary Atlin & Jean-Luc Jannink & Susan R McCouch

January 2015, Volume 11, Issue 1

1-10 An Intracellular Transcriptomic Atlas of the Giant Coenocyte Caulerpa taxifolia
by Aashish Ranjan & Brad T Townsley & Yasunori Ichihashi & Neelima R Sinha & Daniel H Chitwood
1-25 Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
by Anubha Mahajan & Xueling Sim & Hui Jin Ng & Alisa Manning & Manuel A Rivas & Heather M Highland & Adam E Locke & Niels Grarup & Hae Kyung Im & Pablo Cingolani & Jason Flannick & Pierre Fontanillas & Christian Fuchsberger & Kyle J Gaulton & Tanya M Teslovich & N William Rayner & Neil R Robertson & Nicola L Beer & Jana K Rundle & Jette Bork-Jensen & Claes Ladenvall & Christine Blancher & David Buck & Gemma Buck & Noël P Burtt & Stacey Gabriel & Anette P Gjesing & Christopher J Groves & Mette Hollensted & Jeroen R Huyghe & Anne U Jackson & Goo Jun & Johanne Marie Justesen & Massimo Mangino & Jacquelyn Murphy & Matt Neville & Robert Onofrio & Kerrin S Small & Heather M Stringham & Ann-Christine Syvänen & Joseph Trakalo & Goncalo Abecasis & Graeme I Bell & John Blangero & Nancy J Cox & Ravindranath Duggirala & Craig L Hanis & Mark Seielstad & James G Wilson & Cramer Christensen & Ivan Brandslund & Rainer Rauramaa & Gabriela L Surdulescu & Alex S F Doney & Lars Lannfelt & Allan Linneberg & Bo Isomaa & Tiinamaija Tuomi & Marit E Jørgensen & Torben Jørgensen & Johanna Kuusisto & Matti Uusitupa & Veikko Salomaa & Timothy D Spector & Andrew D Morris & Colin N A Palmer & Francis S Collins & Karen L Mohlke & Richard N Bergman & Erik Ingelsson & Lars Lind & Jaakko Tuomilehto & Torben Hansen & Richard M Watanabe & Inga Prokopenko & Josee Dupuis & Fredrik Karpe & Leif Groop & Markku Laakso & Oluf Pedersen & Jose C Florez & Andrew P Morris & David Altshuler & James B Meigs & Michael Boehnke & Mark I McCarthy & Cecilia M Lindgren & Anna L Gloyn & On Behalf of the T2D-GENES consortium and GoT2D consortium

December 2014, Volume 10, Issue 12

1-3 Echoes of the Past: Hereditarianism and A Troublesome Inheritance
by Marcus Feldman
1-10 Large-scale Metabolomic Profiling Identifies Novel Biomarkers for Incident Coronary Heart Disease
by Andrea Ganna & Samira Salihovic & Johan Sundström & Corey D Broeckling & Åsa K Hedman & Patrik K E Magnusson & Nancy L Pedersen & Anders Larsson & Agneta Siegbahn & Mihkel Zilmer & Jessica Prenni & Johan Ärnlöv & Lars Lind & Tove Fall & Erik Ingelsson
1-11 Genome Wide Meta-analysis Highlights the Role of Genetic Variation in RARRES2 in the Regulation of Circulating Serum Chemerin
by Anke Tönjes & Markus Scholz & Jana Breitfeld & Carola Marzi & Harald Grallert & Arnd Gross & Claes Ladenvall & Dorit Schleinitz & Kerstin Krause & Holger Kirsten & Esa Laurila & Jennifer Kriebel & Barbara Thorand & Wolfgang Rathmann & Leif Groop & Inga Prokopenko & Bo Isomaa & Frank Beutner & Jürgen Kratzsch & Joachim Thiery & Mathias Fasshauer & Nora Klöting & Christian Gieger & Matthias Blüher & Michael Stumvoll & Peter Kovacs
1-19 Altered Chromatin Occupancy of Master Regulators Underlies Evolutionary Divergence in the Transcriptional Landscape of Erythroid Differentiation
by Jacob C Ulirsch & Jessica N Lacy & Xiuli An & Narla Mohandas & Tarjei S Mikkelsen & Vijay G Sankaran

November 2014, Volume 10, Issue 11

1-2 Glutamate Receptor Gene GRIN2A, Coffee, and Parkinson Disease
by Taye H Hamza & Erin M Hill-Burns & William K Scott & Jeffrey M Vance & Stewart A Factor & Cyrus P Zabetian & Haydeh Payami
1-9 Regularized Machine Learning in the Genetic Prediction of Complex Traits
by Sebastian Okser & Tapio Pahikkala & Antti Airola & Tapio Salakoski & Samuli Ripatti & Tero Aittokallio
1-9 Lack of Replication of the GRIN2A-by-Coffee Interaction in Parkinson Disease
by Ismaïl Ahmed & Pei-Chen Lee & Christina M Lill & Susan Searles Nielsen & Fanny Artaud & Lisa G Gallagher & Marie-Anne Loriot & Claire Mulot & Magali Nacfer & Tian Liu & Joanna M Biernacka & Sebastian Armasu & Kari Anderson & Federico M Farin & Christina Funch Lassen & Johnni Hansen & Jørgen H Olsen & Lars Bertram & Demetrius M Maraganore & Harvey Checkoway & Beate Ritz & Alexis Elbaz
1-14 Approximation to the Distribution of Fitness Effects across Functional Categories in Human Segregating Polymorphisms
by Fernando Racimo & Joshua G Schraiber
1-15 ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing
by Justin R Pritchard & Michael C Chao & Sören Abel & Brigid M Davis & Catherine Baranowski & Yanjia J Zhang & Eric J Rubin & Matthew K Waldor

October 2014, Volume 10, Issue 10

1-12 Genetic Modifiers of Neurofibromatosis Type 1-Associated Café-au-Lait Macule Count Identified Using Multi-platform Analysis
by Alexander Pemov & Heejong Sung & Paula L Hyland & Jennifer L Sloan & Sarah L Ruppert & Andrea M Baldwin & Joseph F Boland & Sara E Bass & Hyo Jung Lee & Kristine M Jones & Xijun Zhang & NISC Comparative Sequencing Program & James C Mullikin & Brigitte C Widemann & Alexander F Wilson & Douglas R Stewart
1-15 The Proteomic Landscape of the Suprachiasmatic Nucleus Clock Reveals Large-Scale Coordination of Key Biological Processes
by Cheng-Kang Chiang & Neel Mehta & Abhilasha Patel & Peng Zhang & Zhibin Ning & Janice Mayne & Warren Y L Sun & Hai-Ying M Cheng & Daniel Figeys
1-17 Unifying Genetic Canalization, Genetic Constraint, and Genotype-by-Environment Interaction: QTL by Genomic Background by Environment Interaction of Flowering Time in Boechera stricta
by Cheng-Ruei Lee & Jill T Anderson & Thomas Mitchell-Olds

September 2014, Volume 10, Issue 9

1-12 The Association of the Vanin-1 N131S Variant with Blood Pressure Is Mediated by Endoplasmic Reticulum-Associated Degradation and Loss of Function
by Ya-Juan Wang & Bamidele O Tayo & Anupam Bandyopadhyay & Heming Wang & Tao Feng & Nora Franceschini & Hua Tang & Jianmin Gao & Yun Ju Sung & the COGENT BP consortium & Robert C Elston & Scott M Williams & Richard S Cooper & Ting-Wei Mu & Xiaofeng Zhu
1-15 Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments
by Claire S Leblond & Caroline Nava & Anne Polge & Julie Gauthier & Guillaume Huguet & Serge Lumbroso & Fabienne Giuliano & Coline Stordeur & Christel Depienne & Kevin Mouzat & Dalila Pinto & Jennifer Howe & Nathalie Lemière & Christelle M Durand & Jessica Guibert & Elodie Ey & Roberto Toro & Hugo Peyre & Alexandre Mathieu & Frédérique Amsellem & Maria Rastam & I Carina Gillberg & Gudrun A Rappold & Richard Holt & Anthony P Monaco & Elena Maestrini & Pilar Galan & Delphine Heron & Aurélia Jacquette & Alexandra Afenjar & Agnès Rastetter & Alexis Brice & Françoise Devillard & Brigitte Assouline & Fanny Laffargue & James Lespinasse & Jean Chiesa & François Rivier & Dominique Bonneau & Beatrice Regnault & Diana Zelenika & Marc Delepine & Mark Lathrop & Damien Sanlaville & Caroline Schluth-Bolard & Patrick Edery & Laurence Perrin & Anne Claude Tabet & Michael J Schmeisser & Tobias M Boeckers & Mary Coleman & Daisuke Sato & Peter Szatmari & Stephen W Scherer & Guy A Rouleau & Catalina Betancur & Marion Leboyer & Christopher Gillberg & Richard Delorme & Thomas Bourgeron

August 2014, Volume 10, Issue 8

1-14 Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes
by Maggie C Y Ng & Daniel Shriner & Brian H Chen & Jiang Li & Wei-Min Chen & Xiuqing Guo & Jiankang Liu & Suzette J Bielinski & Lisa R Yanek & Michael A Nalls & Mary E Comeau & Laura J Rasmussen-Torvik & Richard A Jensen & Daniel S Evans & Yan V Sun & Ping An & Sanjay R Patel & Yingchang Lu & Jirong Long & Loren L Armstrong & Lynne Wagenknecht & Lingyao Yang & Beverly M Snively & Nicholette D Palmer & Poorva Mudgal & Carl D Langefeld & Keith L Keene & Barry I Freedman & Josyf C Mychaleckyj & Uma Nayak & Leslie J Raffel & Mark O Goodarzi & Y-D Ida Chen & Herman A Taylor Jr. & Adolfo Correa & Mario Sims & David Couper & James S Pankow & Eric Boerwinkle & Adebowale Adeyemo & Ayo Doumatey & Guanjie Chen & Rasika A Mathias & Dhananjay Vaidya & Andrew B Singleton & Alan B Zonderman & Robert P Igo Jr. & John R Sedor & the FIND Consortium & Edmond K Kabagambe & David S Siscovick & Barbara McKnight & Kenneth Rice & Yongmei Liu & Wen-Chi Hsueh & Wei Zhao & Lawrence F Bielak & Aldi Kraja & Michael A Province & Erwin P Bottinger & Omri Gottesman & Qiuyin Cai & Wei Zheng & William J Blot & William L Lowe & Jennifer A Pacheco & Dana C Crawford & the eMERGE Consortium & the DIAGRAM Consortium & Elin Grundberg & the MuTHER Consortium & Stephen S Rich & M Geoffrey Hayes & Xiao-Ou Shu & Ruth J F Loos & Ingrid B Borecki & Patricia A Peyser & Steven R Cummings & Bruce M Psaty & Myriam Fornage & Sudha K Iyengar & Michele K Evans & Diane M Becker & W H Linda Kao & James G Wilson & Jerome I Rotter & Michèle M Sale & Simin Liu & Charles N Rotimi & Donald W Bowden & for the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium
1-20 A Model-Based Approach for Identifying Signatures of Ancient Balancing Selection in Genetic Data
by Michael DeGiorgio & Kirk E Lohmueller & Rasmus Nielsen
1-25 A Population Genetic Signal of Polygenic Adaptation
by Jeremy J Berg & Graham Coop

July 2014, Volume 10, Issue 7

1-11 A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach
by Matthew Traylor & Kari-Matti Mäkelä & Laura L Kilarski & Elizabeth G Holliday & William J Devan & Mike A Nalls & Kerri L Wiggins & Wei Zhao & Yu-Ching Cheng & Sefanja Achterberg & Rainer Malik & Cathie Sudlow & Steve Bevan & Emma Raitoharju & METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2) & Niku Oksala & Vincent Thijs & Robin Lemmens & Arne Lindgren & Agnieszka Slowik & Jane M Maguire & Matthew Walters & Ale Algra & Pankaj Sharma & John R Attia & Giorgio B Boncoraglio & Peter M Rothwell & Paul I W de Bakker & Joshua C Bis & Danish Saleheen & Steven J Kittner & Braxton D Mitchell & Jonathan Rosand & James F Meschia & Christopher Levi & Martin Dichgans & Terho Lehtimäki & Cathryn M Lewis & Hugh S Markus
1-11 Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
by Jennifer L Bolton & Caroline Hayward & Nese Direk & John G Lewis & Geoffrey L Hammond & Lesley A Hill & Anna Anderson & Jennifer Huffman & James F Wilson & Harry Campbell & Igor Rudan & Alan Wright & Nicholas Hastie & Sarah H Wild & Fleur P Velders & Albert Hofman & Andre G Uitterlinden & Jari Lahti & Katri Räikkönen & Eero Kajantie & Elisabeth Widen & Aarno Palotie & Johan G Eriksson & Marika Kaakinen & Marjo-Riitta Järvelin & Nicholas J Timpson & George Davey Smith & Susan M Ring & David M Evans & Beate St Pourcain & Toshiko Tanaka & Yuri Milaneschi & Stefania Bandinelli & Luigi Ferrucci & Pim van der Harst & Judith G M Rosmalen & Stephen J L Bakker & Niek Verweij & Robin P F Dullaart & Anubha Mahajan & Cecilia M Lindgren & Andrew Morris & Lars Lind & Erik Ingelsson & Laura N Anderson & Craig E Pennell & Stephen J Lye & Stephen G Matthews & Joel Eriksson & Dan Mellstrom & Claes Ohlsson & Jackie F Price & Mark W J Strachan & Rebecca M Reynolds & Henning Tiemeier & Brian R Walker & on behalf of the CORtisol NETwork (CORNET) Consortium
1-14 Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
by Ville-Petteri Mäkinen & Mete Civelek & Qingying Meng & Bin Zhang & Jun Zhu & Candace Levian & Tianxiao Huan & Ayellet V Segrè & Sujoy Ghosh & Juan Vivar & Majid Nikpay & Alexandre F R Stewart & Christopher P Nelson & Christina Willenborg & Jeanette Erdmann & Stefan Blakenberg & Christopher J O'Donnell & Winfried März & Reijo Laaksonen & Stephen E Epstein & Sekar Kathiresan & Svati H Shah & Stanley L Hazen & Muredach P Reilly & the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium & Aldons J Lusis & Nilesh J Samani & Heribert Schunkert & Thomas Quertermous & Ruth McPherson & Xia Yang & Themistocles L Assimes
1-20 Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data
by Jakris Eu-ahsunthornwattana & E Nancy Miller & Michaela Fakiola & Wellcome Trust Case Control Consortium 2 & Selma M B Jeronimo & Jenefer M Blackwell & Heather J Cordell

June 2014, Volume 10, Issue 6

1-10 Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study
by Tibor V Varga & Emily Sonestedt & Dmitry Shungin & Robert W Koivula & Göran Hallmans & Stefan A Escher & Inês Barroso & Peter Nilsson & Olle Melander & Marju Orho-Melander & Frida Renström & Paul W Franks
1-18 Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment
by John P Kemp & Carolina Medina-Gomez & Karol Estrada & Beate St Pourcain & Denise H M Heppe & Nicole M Warrington & Ling Oei & Susan M Ring & Claudia J Kruithof & Nicholas J Timpson & Lisa E Wolber & Sjur Reppe & Kaare Gautvik & Elin Grundberg & Bing Ge & Bram van der Eerden & Jeroen van de Peppel & Matthew A Hibbs & Cheryl L Ackert-Bicknell & Kwangbom Choi & Daniel L Koller & Michael J Econs & Frances M K Williams & Tatiana Foroud & M Carola Zillikens & Claes Ohlsson & Albert Hofman & André G Uitterlinden & George Davey Smith & Vincent W V Jaddoe & Jonathan H Tobias & Fernando Rivadeneira & David M Evans

May 2014, Volume 10, Issue 5

1-15 Heterogeneity in the Frequency and Characteristics of Homologous Recombination in Pneumococcal Evolution
by Rafal Mostowy & Nicholas J Croucher & William P Hanage & Simon R Harris & Stephen Bentley & Christophe Fraser
1-15 Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
by Claudia Giambartolomei & Damjan Vukcevic & Eric E Schadt & Lude Franke & Aroon D Hingorani & Chris Wallace & Vincent Plagnol
1-27 Genome-Wide Inference of Ancestral Recombination Graphs
by Matthew D Rasmussen & Melissa J Hubisz & Ilan Gronau & Adam Siepel

April 2014, Volume 10, Issue 4

1-9 Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer
by Jane C Figueiredo & Li Hsu & Carolyn M Hutter & Yi Lin & Peter T Campbell & John A Baron & Sonja I Berndt & Shuo Jiao & Graham Casey & Barbara Fortini & Andrew T Chan & Michelle Cotterchio & Mathieu Lemire & Steven Gallinger & Tabitha A Harrison & Loic Le Marchand & Polly A Newcomb & Martha L Slattery & Bette J Caan & Christopher S Carlson & Brent W Zanke & Stephanie A Rosse & Hermann Brenner & Edward L Giovannucci & Kana Wu & Jenny Chang-Claude & Stephen J Chanock & Keith R Curtis & David Duggan & Jian Gong & Robert W Haile & Richard B Hayes & Michael Hoffmeister & John L Hopper & Mark A Jenkins & Laurence N Kolonel & Conghui Qu & Anja Rudolph & Robert E Schoen & Fredrick R Schumacher & Daniela Seminara & Deanna L Stelling & Stephen N Thibodeau & Mark Thornquist & Greg S Warnick & Brian E Henderson & Cornelia M Ulrich & W James Gauderman & John D Potter & Emily White & Ulrike Peters & on behalf of CCFR & and GECCO
1-10 Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples
by Peter M Visscher & Gibran Hemani & Anna A E Vinkhuyzen & Guo-Bo Chen & Sang Hong Lee & Naomi R Wray & Michael E Goddard & Jian Yang
1-13 A Central Role for GRB10 in Regulation of Islet Function in Man
by Inga Prokopenko & Wenny Poon & Reedik Mägi & Rashmi Prasad B & S Albert Salehi & Peter Almgren & Peter Osmark & Nabila Bouatia-Naji & Nils Wierup & Tove Fall & Alena Stančáková & Adam Barker & Vasiliki Lagou & Clive Osmond & Weijia Xie & Jari Lahti & Anne U Jackson & Yu-Ching Cheng & Jie Liu & Jeffrey R O'Connell & Paul A Blomstedt & Joao Fadista & Sami Alkayyali & Tasnim Dayeh & Emma Ahlqvist & Jalal Taneera & Cecile Lecoeur & Ashish Kumar & Ola Hansson & Karin Hansson & Benjamin F Voight & Hyun Min Kang & Claire Levy-Marchal & Vincent Vatin & Aarno Palotie & Ann-Christine Syvänen & Andrea Mari & Michael N Weedon & Ruth J F Loos & Ken K Ong & Peter Nilsson & Bo Isomaa & Tiinamaija Tuomi & Nicholas J Wareham & Michael Stumvoll & Elisabeth Widen & Timo A Lakka & Claudia Langenberg & Anke Tönjes & Rainer Rauramaa & Johanna Kuusisto & Timothy M Frayling & Philippe Froguel & Mark Walker & Johan G Eriksson & Charlotte Ling & Peter Kovacs & Erik Ingelsson & Mark I McCarthy & Alan R Shuldiner & Kristi D Silver & Markku Laakso & Leif Groop & Valeriya Lyssenko
1-21 A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness
by Jared O'Connell & Deepti Gurdasani & Olivier Delaneau & Nicola Pirastu & Sheila Ulivi & Massimiliano Cocca & Michela Traglia & Jie Huang & Jennifer E Huffman & Igor Rudan & Ruth McQuillan & Ross M Fraser & Harry Campbell & Ozren Polasek & Gershim Asiki & Kenneth Ekoru & Caroline Hayward & Alan F Wright & Veronique Vitart & Pau Navarro & Jean-Francois Zagury & James F Wilson & Daniela Toniolo & Paolo Gasparini & Nicole Soranzo & Manjinder S Sandhu & Jonathan Marchini

March 2014, Volume 10, Issue 3

1-8 ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma
by Monisha E Nongpiur & Chiea Chuen Khor & Hongyan Jia & Belinda K Cornes & Li-Jia Chen & Chunyan Qiao & K Saidas Nair & Ching-Yu Cheng & Liang Xu & Ronnie George & Do Tan & Khaled Abu-Amero & Shamira A Perera & Mineo Ozaki & Takanori Mizoguchi & Yasuo Kurimoto & Sancy Low & Liza-Sharmini A Tajudin & Ching-Lin Ho & Clement C Y Tham & Ileana Soto & Paul T K Chew & Hon-Tym Wong & Balekudaru Shantha & Masako Kuroda & Essam A Osman & Guangxian Tang & Sujie Fan & Hailin Meng & Hua Wang & Bo Feng & Victor H K Yong & Serena M L Ting & Yang Li & Ya-Xing Wang & Zheng Li & Raghavan Lavanya & Ren-Yi Wu & Ying-Feng Zheng & Daniel H Su & Seng-Chee Loon & R Rand Allingham & Michael A Hauser & Nagaswamy Soumittra & Vedam L Ramprasad & Naushin Waseem & Azhany Yaakub & Kee-Seng Chia & Govindasamy Kumaramanickavel & Tina T Wong & Alicia C How & Tran Nguyen Bich Chau & Cameron P Simmons & Jin-Xin Bei & Yi-Xin Zeng & Shomi S Bhattacharya & Mingzhi Zhang & Donald T Tan & Yik-Ying Teo & Saleh A Al-Obeidan & Do Nhu Hon & E-Shyong Tai & Seang-Mei Saw & Paul J Foster & Lingam Vijaya & Jost B Jonas & Tien-Yin Wong & Simon W M John & Chi-Pui Pang & Eranga N Vithana & Ningli Wang & Tin Aung
1-13 Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with Ischemic Stroke
by Stephen R Williams & Qiong Yang & Fang Chen & Xuan Liu & Keith L Keene & Paul Jacques & Wei-Min Chen & Galit Weinstein & Fang-Chi Hsu & Alexa Beiser & Liewei Wang & Ebony Bookman & Kimberly F Doheny & Philip A Wolf & Michelle Zilka & Jacob Selhub & Sarah Nelson & Stephanie M Gogarten & Bradford B Worrall & Sudha Seshadri & Michèle M Sale & the Genomics and Randomized Trials Network & the Framingham Heart Study
1-14 Modeling 3D Facial Shape from DNA
by Peter Claes & Denise K Liberton & Katleen Daniels & Kerri Matthes Rosana & Ellen E Quillen & Laurel N Pearson & Brian McEvoy & Marc Bauchet & Arslan A Zaidi & Wei Yao & Hua Tang & Gregory S Barsh & Devin M Absher & David A Puts & Jorge Rocha & Sandra Beleza & Rinaldo W Pereira & Gareth Baynam & Paul Suetens & Dirk Vandermeulen & Jennifer K Wagner & James S Boster & Mark D Shriver
1-23 A Multi-Trait, Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature, Fatness and Reproduction in Beef Cattle
by Sunduimijid Bolormaa & Jennie E Pryce & Antonio Reverter & Yuandan Zhang & William Barendse & Kathryn Kemper & Bruce Tier & Keith Savin & Ben J Hayes & Michael E Goddard

February 2014, Volume 10, Issue 2

1-12 Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation
by Taru Tukiainen & Matti Pirinen & Antti-Pekka Sarin & Claes Ladenvall & Johannes Kettunen & Terho Lehtimäki & Marja-Liisa Lokki & Markus Perola & Juha Sinisalo & Efthymia Vlachopoulou & Johan G Eriksson & Leif Groop & Antti Jula & Marjo-Riitta Järvelin & Olli T Raitakari & Veikko Salomaa & Samuli Ripatti
1-14 miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis, Migration and Invasion
by Dahu Chen & Yutong Sun & Yuan Yuan & Zhenbo Han & Peijing Zhang & Jinsong Zhang & M James You & Julie Teruya-Feldstein & Min Wang & Sumeet Gupta & Mien-Chie Hung & Han Liang & Li Ma
1-15 Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning
by Gad Abraham & Jason A Tye-Din & Oneil G Bhalala & Adam Kowalczyk & Justin Zobel & Michael Inouye

January 2014, Volume 10, Issue 1

1-13 Functional Divergence and Evolutionary Turnover in Mammalian Phosphoproteomes
by Luca Freschi & Mazid Osseni & Christian R Landry
1-16 Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice
by Eun Yong Kang & Buhm Han & Nicholas Furlotte & Jong Wha J Joo & Diana Shih & Richard C Davis & Aldons J Lusis & Eleazar Eskin

November 2013, Volume 9, Issue 11

1-19 Reconstructing the Population Genetic History of the Caribbean
by Andrés Moreno-Estrada & Simon Gravel & Fouad Zakharia & Jacob L McCauley & Jake K Byrnes & Christopher R Gignoux & Patricia A Ortiz-Tello & Ricardo J Martínez & Dale J Hedges & Richard W Morris & Celeste Eng & Karla Sandoval & Suehelay Acevedo-Acevedo & Paul J Norman & Zulay Layrisse & Peter Parham & Juan Carlos Martínez-Cruzado & Esteban González Burchard & Michael L Cuccaro & Eden R Martin & Carlos D Bustamante
1-28 Pathways-Driven Sparse Regression Identifies Pathways and Genes Associated with High-Density Lipoprotein Cholesterol in Two Asian Cohorts
by Matt Silver & Peng Chen & Ruoying Li & Ching-Yu Cheng & Tien-Yin Wong & E-Shyong Tai & Yik-Ying Teo & Giovanni Montana

October 2013, Volume 9, Issue 10

1-10 Conserved Translatome Remodeling in Nematode Species Executing a Shared Developmental Transition
by Michael Stadler & Andrew Fire
1-15 Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates
by David M Evans & Marie Jo A Brion & Lavinia Paternoster & John P Kemp & George McMahon & Marcus Munafò & John B Whitfield & Sarah E Medland & Grant W Montgomery & The GIANT consortium & The CRP consortium & The TAG Consortium & Nicholas J Timpson & Beate St. Pourcain & Debbie A Lawlor & Nicholas G Martin & Abbas Dehghan & Joel Hirschhorn & George Davey Smith

September 2013, Volume 9, Issue 9

1-11 Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill
by William M Brandler & Andrew P Morris & David M Evans & Thomas S Scerri & John P Kemp & Nicholas J Timpson & Beate St Pourcain & George Davey Smith & Susan M Ring & John Stein & Anthony P Monaco & Joel B Talcott & Simon E Fisher & Caleb Webber & Silvia Paracchini
1-12 Functional Dissection of Regulatory Models Using Gene Expression Data of Deletion Mutants
by Jin'e Li & Yi Liu & Min Liu & Jing-Dong J Han
1-13 IL-17 Attenuates Degradation of ARE-mRNAs by Changing the Cooperation between AU-Binding Proteins and microRNA16
by Saheli Chowdhury & Annemiek Dijkhuis & Sabrina Steiert & René Lutter
1-13 Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations
by Conall M O'Seaghdha & Hongsheng Wu & Qiong Yang & Karen Kapur & Idris Guessous & Annie Mercier Zuber & Anna Köttgen & Candice Stoudmann & Alexander Teumer & Zoltán Kutalik & Massimo Mangino & Abbas Dehghan & Weihua Zhang & Gudny Eiriksdottir & Guo Li & Toshiko Tanaka & Laura Portas & Lorna M Lopez & Caroline Hayward & Kurt Lohman & Koichi Matsuda & Sandosh Padmanabhan & Dmitri Firsov & Rossella Sorice & Sheila Ulivi & A Catharina Brockhaus & Marcus E Kleber & Anubha Mahajan & Florian D Ernst & Vilmundur Gudnason & Lenore J Launer & Aurelien Mace & Eric Boerwinckle & Dan E Arking & Chizu Tanikawa & Yusuke Nakamura & Morris J Brown & Jean-Michel Gaspoz & Jean-Marc Theler & David S Siscovick & Bruce M Psaty & Sven Bergmann & Peter Vollenweider & Veronique Vitart & Alan F Wright & Tatijana Zemunik & Mladen Boban & Ivana Kolcic & Pau Navarro & Edward M Brown & Karol Estrada & Jingzhong Ding & Tamara B Harris & Stefania Bandinelli & Dena Hernandez & Andrew B Singleton & Giorgia Girotto & Daniela Ruggiero & Adamo Pio d'Adamo & Antonietta Robino & Thomas Meitinger & Christa Meisinger & Gail Davies & John M Starr & John C Chambers & Bernhard O Boehm & Bernhard R Winkelmann & Jie Huang & Federico Murgia & Sarah H Wild & Harry Campbell & Andrew P Morris & Oscar H Franco & Albert Hofman & Andre G Uitterlinden & Fernando Rivadeneira & Uwe Völker & Anke Hannemann & Reiner Biffar & Wolfgang Hoffmann & So–Youn Shin & Pierre Lescuyer & Hughes Henry & Claudia Schurmann & The SUNLIGHT consortium & The GEFOS consortium & Patricia B Munroe & Paolo Gasparini & Nicola Pirastu & Marina Ciullo & Christian Gieger & Winfried März & Lars Lind & Tim D Spector & Albert V Smith & Igor Rudan & James F Wilson & Ozren Polasek & Ian J Deary & Mario Pirastu & Luigi Ferrucci & Yongmei Liu & Bryan Kestenbaum & Jaspal S Kooner & Jacqueline C M Witteman & Matthias Nauck & W H Linda Kao & Henri Wallaschofski & Olivier Bonny & Caroline S Fox & Murielle Bochud
1-13 Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking
by Ian C Scott & Seth D Seegobin & Sophia Steer & Rachael Tan & Paola Forabosco & Anne Hinks & Stephen Eyre & Ann W Morgan & Anthony G Wilson & Lynne J Hocking & Paul Wordsworth & Anne Barton & Jane Worthington & Andrew P Cope & Cathryn M Lewis
1-16 Ablating Adult Neurogenesis in the Rat Has No Effect on Spatial Processing: Evidence from a Novel Pharmacogenetic Model
by James O Groves & Isla Leslie & Guo-Jen Huang & Stephen B McHugh & Amy Taylor & Richard Mott & Marcus Munafò & David M Bannerman & Jonathan Flint
1-18 Extensive Divergence of Transcription Factor Binding in Drosophila Embryos with Highly Conserved Gene Expression
by Mathilde Paris & Tommy Kaplan & Xiao Yong Li & Jacqueline E Villalta & Susan E Lott & Michael B Eisen
1-19 N-acetylglucosamine (GlcNAc) Triggers a Rapid, Temperature-Responsive Morphogenetic Program in Thermally Dimorphic Fungi
by Sarah A Gilmore & Shamoon Naseem & James B Konopka & Anita Sil

August 2013, Volume 9, Issue 8

1-8 A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits
by Geraldine M Clarke & Manuel A Rivas & Andrew P Morris
1-15 Histone Variant HTZ1 Shows Extensive Epistasis with, but Does Not Increase Robustness to, New Mutations
by Joshua B Richardson & Locke D Uppendahl & Maria K Traficante & Sasha F Levy & Mark L Siegal
1-16 Re-Ranking Sequencing Variants in the Post-GWAS Era for Accurate Causal Variant Identification
by Laura L Faye & Mitchell J Machiela & Peter Kraft & Shelley B Bull & Lei Sun
1-16 Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci
by Ching-Ti Liu & Keri L Monda & Kira C Taylor & Leslie Lange & Ellen W Demerath & Walter Palmas & Mary K Wojczynski & Jaclyn C Ellis & Mara Z Vitolins & Simin Liu & George J Papanicolaou & Marguerite R Irvin & Luting Xue & Paula J Griffin & Michael A Nalls & Adebowale Adeyemo & Jiankang Liu & Guo Li & Edward A Ruiz-Narvaez & Wei-Min Chen & Fang Chen & Brian E Henderson & Robert C Millikan & Christine B Ambrosone & Sara S Strom & Xiuqing Guo & Jeanette S Andrews & Yan V Sun & Thomas H Mosley & Lisa R Yanek & Daniel Shriner & Talin Haritunians & Jerome I Rotter & Elizabeth K Speliotes & Megan Smith & Lynn Rosenberg & Josyf Mychaleckyj & Uma Nayak & Ida Spruill & W Timothy Garvey & Curtis Pettaway & Sarah Nyante & Elisa V Bandera & Angela F Britton & Alan B Zonderman & Laura J Rasmussen-Torvik & Yii-Der Ida Chen & Jingzhong Ding & Kurt Lohman & Stephen B Kritchevsky & Wei Zhao & Patricia A Peyser & Sharon L R Kardia & Edmond Kabagambe & Ulrich Broeckel & Guanjie Chen & Jie Zhou & Sylvia Wassertheil-Smoller & Marian L Neuhouser & Evadnie Rampersaud & Bruce Psaty & Charles Kooperberg & JoAnn E Manson & Lewis H Kuller & Heather M Ochs-Balcom & Karen C Johnson & Lara Sucheston & Jose M Ordovas & Julie R Palmer & Christopher A Haiman & Barbara McKnight & Barbara V Howard & Diane M Becker & Lawrence F Bielak & Yongmei Liu & Matthew A Allison & Struan F A Grant & Gregory L Burke & Sanjay R Patel & Pamela J Schreiner & Ingrid B Borecki & Michele K Evans & Herman Taylor & Michele M Sale & Virginia Howard & Christopher S Carlson & Charles N Rotimi & Mary Cushman & Tamara B Harris & Alexander P Reiner & L Adrienne Cupples & Kari E North & Caroline S Fox
1-16 Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels
by Gian Andri Thun & Medea Imboden & Ilaria Ferrarotti & Ashish Kumar & Ma'en Obeidat & Michele Zorzetto & Margot Haun & Ivan Curjuric & Alexessander Couto Alves & Victoria E Jackson & Eva Albrecht & Janina S Ried & Alexander Teumer & Lorna M Lopez & Jennifer E Huffman & Stefan Enroth & Yohan Bossé & Ke Hao & Wim Timens & Ulf Gyllensten & Ozren Polasek & James F Wilson & Igor Rudan & Caroline Hayward & Andrew J Sandford & Ian J Deary & Beate Koch & Eva Reischl & Holger Schulz & Jennie Hui & Alan L James & Thierry Rochat & Erich W Russi & Marjo-Riitta Jarvelin & David P Strachan & Ian P Hall & Martin D Tobin & Morten Dahl & Sune Fallgaard Nielsen & Børge G Nordestgaard & Florian Kronenberg & Maurizio Luisetti & Nicole M Probst-Hensch
1-17 GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
by Leonardo Bottolo & Marc Chadeau-Hyam & David I Hastie & Tanja Zeller & Benoit Liquet & Paul Newcombe & Loic Yengo & Philipp S Wild & Arne Schillert & Andreas Ziegler & Sune F Nielsen & Adam S Butterworth & Weang Kee Ho & Raphaële Castagné & Thomas Munzel & David Tregouet & Mario Falchi & François Cambien & Børge G Nordestgaard & Fredéric Fumeron & Anne Tybjærg-Hansen & Philippe Froguel & John Danesh & Enrico Petretto & Stefan Blankenberg & Laurence Tiret & Sylvia Richardson

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