Knowledge, understanding and the dynamics of medical innovation
This paper investigates the processes by which scientific knowledge is created and legitimized. It focuses on scientific developments in a branch of medicine and explores the pathways through which the growth of knowledge enables advances in medical science and in clinical practice. This work draws conceptually on evolutionary approaches to technological change. The empirical part presents a longitudinal analysis of a database of scientific publications in the field of ophthalmology over a period of 50 years. Such an exercise allows us to identify pathways of shared understanding on a disease area, and to map out distinctive trajectories followed by the ophthalmology research community. The paper also contributes to general understanding of the innovation process by supporting the notion that knowledge coordination is a distributed process that cuts across and connects complementary areas of expertise.
|Date of creation:||01 Apr 2008|
|Date of revision:|
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- Davide Consoli & Ronnie Ramlogan, 2008. "Out of sight: problem sequences and epistemic boundaries of medical know-how on glaucoma," Journal of Evolutionary Economics, Springer, vol. 18(1), pages 31-56, February.
- Antonelli, Cristiano, 2001. "The Microeconomics of Technological Systems," OUP Catalogue, Oxford University Press, number 9780199245536, June.
- Richard R. Nelson, 1995. "Recent Evolutionary Theorizing about Economic Change," Journal of Economic Literature, American Economic Association, vol. 33(1), pages 48-90, March.
- Metcalfe, J S, 2001. "Institutions and Progress," Industrial and Corporate Change, Oxford University Press, vol. 10(3), pages 561-86, September.
- Paul A. David, .
"Path Dependence, its critics, and the quest for 'historical economics',"
00011, Stanford University, Department of Economics.
- Paul A.David, 2005. "Path dependence, its critics and the quest for ‘historical economics’," Economic History 0502003, EconWPA.
- B Kogut & U Zander, 2003. "Knowledge of the firm and the evolutionary theory of the multinational corporation," Journal of International Business Studies, Palgrave Macmillan, vol. 34(6), pages 516-529, November.
- Metcalfe, J.S. & James, Andrew & Mina, Andrea, 2005. "Emergent innovation systems and the delivery of clinical services: The case of intra-ocular lenses," Research Policy, Elsevier, vol. 34(9), pages 1283-1304, November.
- Brian J. Loasby, 2001. "Time, knowledge and evolutionary dynamics: why connections matter," Journal of Evolutionary Economics, Springer, vol. 11(4), pages 393-412.
- Nelson, Richard R., 2003.
"On the uneven evolution of human know-how,"
Elsevier, vol. 32(6), pages 909-922, June.
- Mina, A. & Ramlogan, R. & Tampubolon, G. & Metcalfe, J.S., 2007. "Mapping evolutionary trajectories: Applications to the growth and transformation of medical knowledge," Research Policy, Elsevier, vol. 36(5), pages 789-806, June.
- Pierre Garrouste & Stavros Iaonnides, 2001. "Evolution and Path-Dependency in Economic Ideas: Past and Present," Post-Print halshs-00274526, HAL.
- Leydesdorff, Loet & Gauthier, Elaine, 1996. "The evaluation of national performance in selected priority areas using scientometric methods," Research Policy, Elsevier, vol. 25(3), pages 431-450, May.
- Brian J. Loasby, .
"The Organisation of Capabilities,"
Working Papers Series
96/6, University of Stirling, Division of Economics.
- Verspagen, B., 2005.
"Mapping Technological Trajectories as Patent Citation Networks. A Study on the History of Fuel Cell Research,"
05.11, Eindhoven Center for Innovation Studies.
- Bart Verspagen, 2007. "Mapping Technological Trajectories As Patent Citation Networks: A Study On The History Of Fuel Cell Research," Advances in Complex Systems (ACS), World Scientific Publishing Co. Pte. Ltd., vol. 10(01), pages 93-115.
- Verspagen,Bart, 2005. "Mapping Technological Trajectories as Patent Citation Networks. A Study on the History of Fuel Cell Research," Research Memorandum 019, Maastricht University, Maastricht Economic Research Institute on Innovation and Technology (MERIT).
- Roberto Fontana & Alessandro Nuvolari & Bart Verspagen, 2009.
"Mapping technological trajectories as patent citation networks. An application to data communication standards,"
Economics of Innovation and New Technology,
Taylor & Francis Journals, vol. 18(4), pages 311-336.
- Roberto Fontana & Alessandro Nuvolari & Bart Verspagen, 2008. "Mapping Technological Trajectories as Patent Citation Networks. An application to Data Communication Standards," SPRU Working Paper Series 166, SPRU - Science and Technology Policy Research, University of Sussex.
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