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Evolutionary Path and Innovative Development of Pharmaceutical Industrial Cluster—A Case Study of Shijiazhuang, China

Author

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  • Liping Fu

    (College of Management and Economics, Tianjin University, Tianjin 300072, China)

  • Fan Wu

    (College of Management and Economics, Tianjin University, Tianjin 300072, China)

  • Shan Zhang

    (College of Management and Economics, Tianjin University, Tianjin 300072, China)

Abstract

The innovation and development practices of the pharmaceutical industry are of great importance for the continual enhancement of public health. Industrial clusters are one of the important means by which the pharmaceutical industry can be transformed and developed, but there is a lack of research on the evolutionary path and development innovation of pharmaceutical industrial clusters. As a country with a major pharmaceutical industry, the transformation and development path of traditional pharmaceutical industrial clusters in China has important reference value for the sustainable development of the global pharmaceutical industry. Through an analysis of the evolution of traditional pharmaceutical industrial clusters in Shijiazhuang, this study explores the law of the dynamic evolution of pharmaceutical industrial clusters and the associated mechanisms. Specifically, we conclude that the evolutionary path of traditional pharmaceutical industrial clusters can be divided into the government-led pharmaceutical industrial cluster start-up stage, the government-guided pharmaceutical industrial cluster development stage, and the government-served pharmaceutical industrial cluster transformation stage. The operating mechanisms include a self-organization mechanism, an innovation-driven mechanism, and an outward associated mechanism, each of which plays different roles in the different stages of the dynamic evolution of the cluster, and the synergistic operation of the three mechanisms forms an important basis for the evolution of pharmaceutical industrial clusters. We found that the innovation development of traditional pharmaceutical industrial clusters is influenced by the synergy of the self-organization, innovation-driven, and outward associated mechanisms. The self-organization mechanism is a necessary condition for pharmaceutical industrial clusters to realize the transition from disorder to order. The innovation-driven mechanism is the core driving force for the innovative development of pharmaceutical industrial clusters. Finally, the outward associated mechanism is the main means by which pharmaceutical industrial clusters integrate into the global value chain.

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  • Liping Fu & Fan Wu & Shan Zhang, 2022. "Evolutionary Path and Innovative Development of Pharmaceutical Industrial Cluster—A Case Study of Shijiazhuang, China," IJERPH, MDPI, vol. 19(5), pages 1-18, March.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:5:p:2928-:d:762744
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    References listed on IDEAS

    as
    1. Vito Tanzi & Howell H. Zee, 1997. "Fiscal Policy and Long-Run Growth," IMF Staff Papers, Palgrave Macmillan, vol. 44(2), pages 179-209, June.
    2. Keun Lee & Marina Szapiro & Zhuqing Mao, 2018. "Correction to: From Global Value Chains (GVC) to Innovation Systems for Local Value Chains and Knowledge Creation," The European Journal of Development Research, Palgrave Macmillan;European Association of Development Research and Training Institutes (EADI), vol. 30(3), pages 575-575, July.
    3. Cooke, Philip & Gomez Uranga, Mikel & Etxebarria, Goio, 1997. "Regional innovation systems: Institutional and organisational dimensions," Research Policy, Elsevier, vol. 26(4-5), pages 475-491, December.
    4. Gary Gereffi & Joonkoo Lee, 2016. "Economic and Social Upgrading in Global Value Chains and Industrial Clusters: Why Governance Matters," Journal of Business Ethics, Springer, vol. 133(1), pages 25-38, January.
    5. Krugman, Paul, 1991. "Increasing Returns and Economic Geography," Journal of Political Economy, University of Chicago Press, vol. 99(3), pages 483-499, June.
    6. Ricarda Bouncken & Johanna Gast & Sascha Kraus & Marcel Bogers, 2015. "Coopetition: a systematic review, synthesis, and future research directions," Post-Print hal-02018068, HAL.
    7. Elisa Barbieri & Manli Huang & Shenglei Pi & Mattia Tassinari, 2017. "Restructuring the Production of Medicines: An Investigation on the Pharmaceutical Sector in China and the Role of Mergers and Acquisitions," IJERPH, MDPI, vol. 14(10), pages 1-21, October.
    8. Ricarda Bouncken & Johanna Gast & Sascha Kraus & Marcel Bogers, 2015. "Coopetition: a systematic review, synthesis, and future research directions," Post-Print hal-02945341, HAL.
    9. Ayda Eraydin & Bilge Armatli-Köroğlu, 2005. "Innovation, networking and the new industrial clusters: the characteristics of networks and local innovation capabilities in the Turkish industrial clusters," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 17(4), pages 237-266, July.
    10. Achilladelis, Basil & Antonakis, Nicholas, 2001. "The dynamics of technological innovation: the case of the pharmaceutical industry," Research Policy, Elsevier, vol. 30(4), pages 535-588, April.
    11. Qi Zhong & Tang Tang, 2018. "Impact of Government Intervention on Industrial Cluster Innovation Network in Developing Countries," Emerging Markets Finance and Trade, Taylor & Francis Journals, vol. 54(14), pages 3351-3365, November.
    12. Christian Lechner & Christophe Leyronas, 2012. "The competitive advantage of cluster firms: the priority of regional network position over extra-regional networks -- a study of a French high-tech cluster," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 24(5-6), pages 457-473, June.
    13. Ekaterina Turkina & Ari Van Assche, 2018. "Global Connectedness and Local Innovation in Industrial Clusters," CIRANO Working Papers 2018s-12, CIRANO.
    14. Judith Terstriep & Christian Lüthje, 2018. "Innovation, knowledge and relations – on the role of clusters for firms’ innovativeness," European Planning Studies, Taylor & Francis Journals, vol. 26(11), pages 2167-2199, November.
    15. Hiroyuki Okamuro & Junichi Nishimura, 2015. "Local Management of National Cluster Policies: Comparative Case Studies of Japanese, German, and French Biotechnology Clusters," Administrative Sciences, MDPI, vol. 5(4), pages 1-27, November.
    16. Ekaterina Turkina & Ari Van Assche, 2018. "Global connectedness and local innovation in industrial clusters," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 49(6), pages 706-728, August.
    17. Anne-Lorène Vernay & Beatrice D’Ippolito & Jonatan Pinkse, 2018. "Can the government create a vibrant cluster? Understanding the impact of cluster policy on the development of a cluster," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 30(7-8), pages 901-919, August.
    18. Landesmann, Michael A. & Stöllinger, Roman, 2019. "Structural change, trade and global production networks: An ‘appropriate industrial policy’ for peripheral and catching-up economies," Structural Change and Economic Dynamics, Elsevier, vol. 48(C), pages 7-23.
    19. Jose Antonio Belso-Martinez & Isabel Diez-Vial & Maria Jose Lopez-Sanchez & Rosario Mateu-Garcia, 2018. "The brokerage role of supporting organizations inside clusters: how does it work?," European Planning Studies, Taylor & Francis Journals, vol. 26(4), pages 706-725, April.
    20. John Humphrey & Hubert Schmitz, 2002. "How does insertion in global value chains affect upgrading in industrial clusters?," Regional Studies, Taylor & Francis Journals, vol. 36(9), pages 1017-1027.
    21. Vlaisavljevic, Vesna & Medina, Carmen Cabello & Van Looy, Bart, 2020. "The role of policies and the contribution of cluster agency in the development of biotech open innovation ecosystem," Technological Forecasting and Social Change, Elsevier, vol. 155(C).
    22. Catherine Lecocq & Bart Van Looy, 2016. "Editor's Choice What differentiates top regions in the field of biotechnology? An empirical study of the texture characteristics of biotech regions in North America, Europe, and Asia-Pacific," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 25(4), pages 671-688.
    23. Jianyi Li & Douglas Webster & Jianming Cai & Larissa Muller, 2019. "Innovation Clusters Revisited: On Dimensions of Agglomeration, Institution, and Built-Environment," Sustainability, MDPI, vol. 11(12), pages 1-15, June.
    24. Maria Minniti, 2008. "The Role of Government Policy on Entrepreneurial Activity: Productive, Unproductive, or Destructive?," Entrepreneurship Theory and Practice, , vol. 32(5), pages 779-790, September.
    25. Rachel Hilliard & David Jacobson, 2011. "Cluster versus Firm-specific Factors in the Development of Dynamic Capabilities in the Pharmaceutical Industry in Ireland: A Study of Responses to Changes in Environmental Protection Regulations," Regional Studies, Taylor & Francis Journals, vol. 45(10), pages 1319-1328, November.
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