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Biomed Europa: After the coronavirus, a public infrastructure to overcome the pharmaceutical oligopoly

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  • Massimo Florio
  • Simona Gamba

Abstract

After a brief analysis of the causes underlying the failure of both governments and the pharma industry in terms of preparedness for the COVID‐19 pandemic, and after a discussion of further risks of health emergencies in the coming decades, this paper proposes a new public policy approach. The proposal aims at a major European initiative for the provision of research and development (R&D) in the biomedical field, based on public health priorities. A plan is discussed for an international, interconnected, transparent, science‐informed and publicly funded research infrastructure for pharmaceutical and biomedical research combined with a public enterprise: Biomed Europa. The proposed platform aims to identify research priorities in the public health sector, focusing its efforts on the development of preventive and therapeutic strategies against those diseases that will pose the greatest threats to human and social welfare over future decades. Biomed Europa could be managed as both an international research infrastructure, along the model of CERN, or the EMBL (European Molecular Biology Laboratory, Heidelberg) and as a knowledge‐intensive public enterprise with an industrial policy mission, such as the ESA (European Space Agency).

Suggested Citation

  • Massimo Florio & Simona Gamba, 2021. "Biomed Europa: After the coronavirus, a public infrastructure to overcome the pharmaceutical oligopoly," Annals of Public and Cooperative Economics, Wiley Blackwell, vol. 92(3), pages 387-409, September.
  • Handle: RePEc:bla:annpce:v:92:y:2021:i:3:p:387-409
    DOI: 10.1111/apce.12341
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    1. Philippe Aghion & Mathias Dewatripont & Julian Kolev & Fiona Murray & Scott Stern, 2016. "Of Mice and Academics: Examining the Effect of Openness on Innovation," PSE-Ecole d'économie de Paris (Postprint) halshs-01496928, HAL.
    2. Comanor, William S. & Scherer, F.M., 2013. "Mergers and innovation in the pharmaceutical industry," Journal of Health Economics, Elsevier, vol. 32(1), pages 106-113.
    3. Stern, Ariel Dora, 2017. "Innovation under regulatory uncertainty: Evidence from medical technology," Journal of Public Economics, Elsevier, vol. 145(C), pages 181-200.
    4. Jeffrey Clemens, 2012. "The Effect of U.S. Health Insurance Expansions on Medical Innovation," Discussion Papers 11-016, Stanford Institute for Economic Policy Research.
    5. Lakdawalla, Darius & Malani, Anup & Reif, Julian, 2017. "The insurance value of medical innovation," Journal of Public Economics, Elsevier, vol. 145(C), pages 94-102.
    6. Pierre Dubois & Olivier de Mouzon & Fiona Scott-Morton & Paul Seabright, 2015. "Market size and pharmaceutical innovation," RAND Journal of Economics, RAND Corporation, vol. 46(4), pages 844-871, October.
    7. Rena M. Conti & Jonathan Gruber & Daniel A. Ollendorf & Peter J. Neumann, 2020. "Valuing Rare Pediatric Drugs: An Economics Perspective," NBER Working Papers 27978, National Bureau of Economic Research, Inc.
    8. Gamba, Simona, 2017. "The Effect of Intellectual Property Rights on Domestic Innovation in the Pharmaceutical Sector," World Development, Elsevier, vol. 99(C), pages 15-27.
    9. Daron Acemoglu & Joshua Linn, 2004. "Market Size in Innovation: Theory and Evidence from the Pharmaceutical Industry," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 119(3), pages 1049-1090.
    10. Congressional Budget Office, 2021. "Research and Development in the Pharmaceutical Industry," Reports 57025, Congressional Budget Office.
    11. Fiona Murray & Philippe Aghion & Mathias Dewatripont & Julian Kolev & Scott Stern, 2016. "Of Mice and Academics: Examining the Effect of Openness on Innovation," American Economic Journal: Economic Policy, American Economic Association, vol. 8(1), pages 212-252, February.
    12. Simona Gamba & Laura Magazzini & Paolo Pertile, 2019. "R&D and market size: who benefits from orphan drug regulation?," Working Papers 09/2019, University of Verona, Department of Economics.
    13. Gamba, Simona & Magazzini, Laura & Pertile, Paolo, 2021. "R&D and market size: Who benefits from orphan drug legislation?," Journal of Health Economics, Elsevier, vol. 80(C).
    14. Fan, Victoria Y & Jamison, Dean T & Summers, Lawrence H, 2018. "Pandemic risk: how large are the expected losses?," Scholarly Articles 35014363, Harvard Kennedy School of Government.
    15. Jobjörnsson, Sebastian & Forster, Martin & Pertile, Paolo & Burman, Carl-Fredrik, 2016. "Late-stage pharmaceutical R&D and pricing policies under two-stage regulation," Journal of Health Economics, Elsevier, vol. 50(C), pages 298-311.
    16. Sandeep Juneja & Aastha Gupta & Suerie Moon & Stephen Resch, 2017. "Projected savings through public health voluntary licences of HIV drugs negotiated by the Medicines Patent Pool (MPP)," PLOS ONE, Public Library of Science, vol. 12(5), pages 1-15, May.
    17. Ayotte, Kenneth & Hansmann, Henry, 2015. "A nexus of contracts theory of legal entities," International Review of Law and Economics, Elsevier, vol. 42(C), pages 1-12.
    18. Jan E. Carette & Matthijs Raaben & Anthony C. Wong & Andrew S. Herbert & Gregor Obernosterer & Nirupama Mulherkar & Ana I. Kuehne & Philip J. Kranzusch & April M. Griffin & Gordon Ruthel & Paola Dal C, 2011. "Ebola virus entry requires the cholesterol transporter Niemann–Pick C1," Nature, Nature, vol. 477(7364), pages 340-343, September.
    19. Manica Balasegaram & Peter Kolb & John McKew & Jaykumar Menon & Piero Olliaro & Tomasz Sablinski & Zakir Thomas & Matthew H Todd & Els Torreele & John Wilbanks, 2017. "An open source pharma roadmap," PLOS Medicine, Public Library of Science, vol. 14(4), pages 1-7, April.
    20. Jeffrey Clemens & Parker Rogers, 2020. "Demand Shocks, Procurement Policies, and the Nature of Medical Innovation: Evidence from Wartime Prosthetic Device Patents," NBER Working Papers 26679, National Bureau of Economic Research, Inc.
    21. Amy Finkelstein, 2004. "Static and Dynamic Effects of Health Policy: Evidence from the Vaccine Industry," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 119(2), pages 527-564.
    22. Marceline Côté & John Misasi & Tao Ren & Anna Bruchez & Kyungae Lee & Claire Marie Filone & Lisa Hensley & Qi Li & Daniel Ory & Kartik Chandran & James Cunningham, 2011. "Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection," Nature, Nature, vol. 477(7364), pages 344-348, September.
    23. Nicola Dimitri, 2012. "R&D Incentives for Neglected Diseases," PLOS ONE, Public Library of Science, vol. 7(12), pages 1-4, December.
    24. Eliana Barrenho & Marisa Miraldo & Peter C. Smith, 2019. "Does global drug innovation correspond to burden of disease? The neglected diseases in developed and developing countries," Health Economics, John Wiley & Sons, Ltd., vol. 28(1), pages 123-143, January.
    25. Blume-Kohout, Margaret E. & Sood, Neeraj, 2013. "Market size and innovation: Effects of Medicare Part D on pharmaceutical research and development," Journal of Public Economics, Elsevier, vol. 97(C), pages 327-336.
    26. Ryan Lampe & Petra Moser, 2016. "Patent Pools, Competition, and Innovation—Evidence from 20 US Industries under the New Deal," The Journal of Law, Economics, and Organization, Oxford University Press, vol. 32(1), pages 1-36.
    27. Rea,Philip A. & Pauly,Mark V. & Burns,Lawton R., 2018. "Managing Discovery in the Life Sciences," Cambridge Books, Cambridge University Press, number 9781107130906.
    28. Nicola Dimitri, 2012. "R&D for Neglected Diseases," Working Papers 2012/07, Maastricht School of Management.
    29. Anthony B. Atkinson & Joseph E. Stiglitz, 2015. "Lectures on Public Economics Updated edition," Economics Books, Princeton University Press, edition 2, number 10493.
    30. Rea,Philip A. & Pauly,Mark V. & Burns,Lawton R., 2018. "Managing Discovery in the Life Sciences," Cambridge Books, Cambridge University Press, number 9781107577305.
    31. Leila Agha & Soomi Kim & Danielle Li, 2020. "Insurance Design and Pharmaceutical Innovation," NBER Working Papers 27563, National Bureau of Economic Research, Inc.
    32. Nord, Erik & Richardson, Jeff & Street, Andrew & Kuhse, Helga & Singer, Peter, 1995. "Maximizing health benefits vs egalitarianism: An Australian survey of health issues," Social Science & Medicine, Elsevier, vol. 41(10), pages 1429-1437, November.
    33. Franco Malerba & Luigi Orsenigo, 2015. "The evolution of the pharmaceutical industry," Business History, Taylor & Francis Journals, vol. 57(5), pages 664-687, July.
    34. Luc Bernier & Massimo Florio & Philippe Bance, 2020. "The Routledge Handbook of State-Owned Enterprises," Post-Print hal-02613944, HAL.
    35. Henry Hansmann, 2012. "Ownership and Organizational Form [The Handbook of Organizational Economics]," Introductory Chapters,, Princeton University Press.
    36. Cockburn, Iain M. & Henderson, Rebecca M., 2001. "Scale and scope in drug development: unpacking the advantages of size in pharmaceutical research," Journal of Health Economics, Elsevier, vol. 20(6), pages 1033-1057, November.
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    2. Giovanni Dosi, 2021. "Some policy lessons from medical/therapeutic responses to the COVID-19 Crisis: A rich research system for knowledge generation and dysfunctional institutions for its exploitation," LEM Papers Series 2021/19, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
    3. Giovanni Dosi, 2021. "Policy Lessons From Medical Responses to the COVID-19 Crisis," Intereconomics: Review of European Economic Policy, Springer;ZBW - Leibniz Information Centre for Economics;Centre for European Policy Studies (CEPS), vol. 56(6), pages 337-340, November.
    4. Anna Balestra & Raul Caruso, 2023. "Vaccines between war and market," International Area Studies Review, Center for International Area Studies, Hankuk University of Foreign Studies, vol. 26(1), pages 24-39, March.
    5. Emanuela Sirtori & Alessandra Caputo & Domenico Scalera, 2021. "Patterns of development in the European biopharmaceutical industry. A network analysis of cross-sectoral linkages (2000-2016)," Working Papers 202101, CSIL Centre for Industrial Studies.
    6. Els Torreele, 2020. "Business-as-Usual will not Deliver the COVID-19 Vaccines We Need," Development, Palgrave Macmillan;Society for International Deveopment, vol. 63(2), pages 191-199, December.
    7. Nazim Hajiyev & Manafova Mansura & Elena Sverdlikova & Roman Safronov & Tatyana Vityutina, 2021. "Oligopoly Trends in Energy Markets: Causes, Crisis of Competition, and Sectoral Development Strategies," International Journal of Energy Economics and Policy, Econjournals, vol. 11(6), pages 392-400.

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    More about this item

    JEL classification:

    • H51 - Public Economics - - National Government Expenditures and Related Policies - - - Government Expenditures and Health
    • I11 - Health, Education, and Welfare - - Health - - - Analysis of Health Care Markets
    • L32 - Industrial Organization - - Nonprofit Organizations and Public Enterprise - - - Public Enterprises; Public-Private Enterprises
    • O32 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Management of Technological Innovation and R&D

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