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Role of external knowledge flows in cluster upgrading: an empirical analysis of the Mirandola biomedical district in Italy

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  • Sandrine Labory

Abstract

The paper analyses the role of external knowledge flows in the upgrading of the biomedical district of Mirandola, Emilia-Romagna region, in Italy. The district produces two types of products, namely disposables and electromedical machines, and the paper considers this second production type. The Mirandola district has been able to maintain a relatively good competitive position. The paper shows that while all firms in this sector in this region tend to have fairly good performance in terms of size and revenue growth, a significant difference exists in terms of innovation performance. Firms in the Mirandola district produce more patents and more scientific publications. From a methodological point of view, negative binomial regressions are made on the determinants of patenting and publishing activity by firms. Two major factors seem to explain the superior performance in terms of innovation. First, the significant role of the leader firms in the district. Second, linkages external to the district, namely relationships with research centres (universities in particular) located not only in the region but also in the rest of the country and abroad. The importance of external relations and institutional diversity (in terms of variety of institutions collaborating in scientific publications), appear to grow over time.

Suggested Citation

  • Sandrine Labory, 2011. "Role of external knowledge flows in cluster upgrading: an empirical analysis of the Mirandola biomedical district in Italy," Working Papers 201114, University of Ferrara, Department of Economics.
  • Handle: RePEc:udf:wpaper:201114
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    1. Michelle Gittelman, 2005. "What Makes Research Socially Useful ? Complementarities between in-House Research and Firm-University Collaboration in Biotechnology," Revue d'Économie Industrielle, Programme National Persée, vol. 110(1), pages 57-73.
    2. J Calvert & P Patel, 2003. "University-industry research collaborations in the UK: Bibliometric trends," Science and Public Policy, Oxford University Press, vol. 30(2), pages 85-96, April.
    3. Roberta Rabellotti & Anna Carabelli & Giovanna Hirsch, 2007. "Italian Industrial Districts on the Move: Where Are They Going?," European Planning Studies, Taylor & Francis Journals, vol. 17(1), pages 19-41, July.
    4. Humphrey, John,, 2004. "Upgrading in global value chains," ILO Working Papers 993698523402676, International Labour Organization.
    5. Julien Pénin, 2007. "Open Knowledge Disclosure: An Overview Of The Evidence And Economic Motivations," Journal of Economic Surveys, Wiley Blackwell, vol. 21(2), pages 326-347, April.
    6. Nelson, Richard R., 1990. "U.S. technological leadership: Where did it come from and where did it go?," Research Policy, Elsevier, vol. 19(2), pages 117-132, April.
    7. Day, Marc & Burnett, John & L Forrester, Paul & Hassard, John, 2000. "Britain's last industrial district? A case study of ceramics production," International Journal of Production Economics, Elsevier, vol. 65(1), pages 5-15, April.
    8. Geroski, P. A. & Van Reenen, J. & Walters, C. F., 1997. "How persistently do firms innovate?," Research Policy, Elsevier, vol. 26(1), pages 33-48, March.
    9. Hicks, Diana, 1995. "Published Papers, Tacit Competencies and Corporate Management of the Public/Private Character of Knowledge," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 4(2), pages 401-424.
    10. John Humphrey & Hubert Schmitz, 2002. "How does insertion in global value chains affect upgrading in industrial clusters?," Regional Studies, Taylor & Francis Journals, vol. 36(9), pages 1017-1027.
    11. repec:bla:jindec:v:46:y:1998:i:2:p:157-82 is not listed on IDEAS
    12. Wesley M. Cohen & Richard R. Nelson & John P. Walsh, 2003. "Links and Impacts: The Influence of Public Research on Industrial R&D," Chapters, in: Aldo Geuna & Ammon J. Salter & W. Edward Steinmueller (ed.), Science and Innovation, chapter 4, Edward Elgar Publishing.
    13. Bjørn Asheim & Ron Boschma & Philip Cooke, 2011. "Constructing Regional Advantage: Platform Policies Based on Related Variety and Differentiated Knowledge Bases," Regional Studies, Taylor & Francis Journals, vol. 45(7), pages 893-904.
    14. Hausman, Jerry & Hall, Bronwyn H & Griliches, Zvi, 1984. "Econometric Models for Count Data with an Application to the Patents-R&D Relationship," Econometrica, Econometric Society, vol. 52(4), pages 909-938, July.
    15. N. A. Phelps, 2008. "Cluster or Capture? Manufacturing Foreign Direct Investment, External Economies and Agglomeration," Regional Studies, Taylor & Francis Journals, vol. 42(4), pages 457-473.
    16. Giacomo Becattini & Marco Bellandi & Lisa De Propis (ed.), 2009. "A Handbook of Industrial Districts," Books, Edward Elgar Publishing, number 12736.
    17. Enrico Santarelli, 2004. "Patents and the Technological Performance of District Firms Evidence for the Emilia-Romagna Region of Italy," Papers on Entrepreneurship, Growth and Public Policy 2004-29, Max Planck Institute of Economics, Entrepreneurship, Growth and Public Policy Group.
    18. Susan Christopherson & Jennifer Clark, 2007. "Power in Firm Networks: What it Means for Regional Innovation Systems," Regional Studies, Taylor & Francis Journals, vol. 41(9), pages 1223-1236.
    19. Wolfgang Glänzel & Cornelius de Lange, 2002. "A distributional approach to multinationality measures of international scientific collaboration," Scientometrics, Springer;Akadémiai Kiadó, vol. 54(1), pages 75-89, April.
    20. Wolfgang Glänzel & Rickard Danell & Olle Persson, 2003. "The decline of Swedish neuroscience: Decomposing a bibliometric national science indicator," Scientometrics, Springer;Akadémiai Kiadó, vol. 57(2), pages 197-213, June.
    21. Nathan ROSENBERG, 2009. "Why do firms do basic research (with their own money)?," World Scientific Book Chapters, in: Nathan Rosenberg (ed.), Studies On Science And The Innovation Process Selected Works of Nathan Rosenberg, chapter 11, pages 225-234, World Scientific Publishing Co. Pte. Ltd..
    22. Bonaccorsi, Andrea & Thoma, Grid, 2007. "Institutional complementarity and inventive performance in nano science and technology," Research Policy, Elsevier, vol. 36(6), pages 813-831, July.
    23. Maria Chiarvesio & Eleonora Di Maria & Stefano Micelli, 2008. "Global Value Chains and Open Networks: The Case of Italian Industrial Districts," European Planning Studies, Taylor & Francis Journals, vol. 18(3), pages 333-350, December.
    24. Cainelli, Giulio & Mancinelli, Susanna & Mazzanti, Massimiliano, 2007. "Social capital and innovation dynamics in district-based local systems," Journal of Behavioral and Experimental Economics (formerly The Journal of Socio-Economics), Elsevier, vol. 36(6), pages 932-948, December.
    25. Roberta Rabellotti & Anna Carabelli & Giovanna Hirsch, 2007. "Italian SMEs and industrial districts on the move: Where are they going?," Working Papers 115, SEMEQ Department - Faculty of Economics - University of Eastern Piedmont.
    26. Harald Bathelt & Andersand Malmberg & Peter Maskell, 2002. "Clusters and Knowledge Local Buzz, Global Pipelines and the Process of Knowledge Creation," DRUID Working Papers 02-12, DRUID, Copenhagen Business School, Department of Industrial Economics and Strategy/Aalborg University, Department of Business Studies.
    27. Marco Bellandi, 2011. "Perspectives on Mature Marshallian Industrial Districts," Chapters, in: Philip Cooke & Bjørn Asheim & Ron Boschma & Ron Martin & Dafna Schwartz & Franz Tödtling (ed.), Handbook of Regional Innovation and Growth, chapter 6, Edward Elgar Publishing.
    28. Biggiero, Lucio, 2002. "The Location of Multinationals in Industrial Districts: Knowledge Transfer in Biomedicals," The Journal of Technology Transfer, Springer, vol. 27(1), pages 111-122, January.
    29. Khalid Nadvi, 1999. "Shifting Ties: Social Networks in the Surgical Instrument Cluster of Sialkot, Pakistan," Development and Change, International Institute of Social Studies, vol. 30(1), pages 141-175, January.
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    More about this item

    Keywords

    Innovation; Upgrading; Industrial districts; Biomedical sector;
    All these keywords.

    JEL classification:

    • O31 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Innovation and Invention: Processes and Incentives
    • L60 - Industrial Organization - - Industry Studies: Manufacturing - - - General
    • R11 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General Regional Economics - - - Regional Economic Activity: Growth, Development, Environmental Issues, and Changes

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