Research Network Position and Innovative Performance: Evidence from the Pharmaceutical Industry
This paper explores how and why collaboration with different types of partners and the position within a research network can affect firms' innovative performance in terms of product innovations. A detailed empirical analysis is carried out in the biotechnology and pharmaceutical industry. This industry is characterized by a rapidly developing, complex, and dispersed knowledge base, where one would expect positive benefits from collaboration and the position within a network for innovative output. The paper uses a unique dataset in pharmaceutical cancer research based on scientific co-publications and new drug approvals. We apply social network analysis and count data regressions. We observe that collaboration with a diverse set of partners from academia and the network position in terms of eigenvector centrality is positively related to product innovation. However, we do not find a general positive association between collaboration, particularly with biotechnology companies, and product innovation or between central network positions and product innovation. Therefore, these results require a re-assessment of the role of scientific collaboration and biotechnology companies in the development of the pharmaceutical industry.
|Date of creation:||11 May 2012|
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- Elisa Giuliani, 2007.
"Networks and Heterogeneous Performance of Cluster Firms,"
in: Applied Evolutionary Economics and Economic Geography, chapter 8
Edward Elgar Publishing.
- Elisa Giuliani, 2006. "Networks and heterogeneous performance of cluster firms," Papers in Evolutionary Economic Geography (PEEG) 0602, Utrecht University, Section of Economic Geography, revised Jan 2006.
- Uwe Cantner & Bastian Rake, 2011.
"International Research Networks in Pharmaceuticals: Structure and Dynamics,"
Jena Economic Research Papers
2011-055, Friedrich-Schiller-University Jena.
- Cantner, Uwe & Rake, Bastian, 2014. "International research networks in pharmaceuticals: Structure and dynamics," Research Policy, Elsevier, vol. 43(2), pages 333-348.
- Cockburn, Iain M & Henderson, Rebecca M, 1998. "Absorptive Capacity, Coauthoring Behavior, and the Organization of Research in Drug Discovery," Journal of Industrial Economics, Wiley Blackwell, vol. 46(2), pages 157-82, June.
- Roijakkers, Nadine & Hagedoorn, John, 2006. "Inter-firm R&D partnering in pharmaceutical biotechnology since 1975: Trends, patterns, and networks," Research Policy, Elsevier, vol. 35(3), pages 431-446, April.
- Rothaermel, Frank T., 2001. "Complementary assets, strategic alliances, and the incumbent's advantage: an empirical study of industry and firm effects in the biopharmaceutical industry," Research Policy, Elsevier, vol. 30(8), pages 1235-1251, October.
- Vuong, Quang H, 1989. "Likelihood Ratio Tests for Model Selection and Non-nested Hypotheses," Econometrica, Econometric Society, vol. 57(2), pages 307-33, March.
- Breschi, Stefano & Catalini, Christian, 2010. "Tracing the links between science and technology: An exploratory analysis of scientists' and inventors' networks," Research Policy, Elsevier, vol. 39(1), pages 14-26, February.
- Holger Graf, 2007.
"Gatekeepers in regional networks of innovators,"
Jena Economic Research Papers
2007-054, Friedrich-Schiller-University Jena.
- Wolfgang Becker & Juergen Dietz, 2002.
"R&D Cooperation and Innovation Activities of Firms - Evidence for the German Manufacturing Industry -,"
Discussion Paper Series
222, Universitaet Augsburg, Institute for Economics.
- Becker, Wolfgang & Dietz, Jurgen, 2004. "R&D cooperation and innovation activities of firms--evidence for the German manufacturing industry," Research Policy, Elsevier, vol. 33(2), pages 209-223, March.
- Orsenigo, L. & Pammolli, F. & Riccaboni, Massimo, 2001. "Technological change and network dynamics: Lessons from the pharmaceutical industry," Research Policy, Elsevier, vol. 30(3), pages 485-508, March.
- Malerba, Franco & Orsenigo, Luigi, 1996. "The Dynamics and Evolution of Industries," Industrial and Corporate Change, Oxford University Press, vol. 5(1), pages 51-87.
- Victor Gilsing & Bart Noteboom & Wim Vanhaverbeke & Geert Duysters & Ad van Noord, 2006.
"Network embeddedness and the exploration of novel technologies: technological distance, betweenness centrality and density,"
06-08, Eindhoven Center for Innovation Studies, revised Apr 2006.
- Gilsing, Victor & Nooteboom, Bart & Vanhaverbeke, Wim & Duysters, Geert & van den Oord, Ad, 2008. "Network embeddedness and the exploration of novel technologies: Technological distance, betweenness centrality and density," Research Policy, Elsevier, vol. 37(10), pages 1717-1731, December.
- Gilsing, V.A. & Nooteboom, B. & van Haverbeke, W.P.M. & Duijsters, G.M. & Oord, A., 2008. "Network embeddedness and the exploration of novel technologies : Technological distance, betweenness centrality and density," Other publications TiSEM 762e80f1-0adc-4184-b1be-9, Tilburg University, School of Economics and Management.
- Nooteboom, B. & Gilsing, V.A. & Vanhaverbeke, W.P.M. & Duijsters, G.M. & Oord, A., 2006. "Network Embeddedness and the Exploration of Novel Technologies : Technological Distance, Betweenness Centrality and Density," Discussion Paper 2006-32, Tilburg University, Center for Economic Research.
- Holger Graf & Jens Kruger, 2011.
"The Performance of Gatekeepers in Innovator Networks,"
Industry and Innovation,
Taylor & Francis Journals, vol. 18(1), pages 69-88.
- Holger Graf & Jens J. Krüger, 2009. "The Performance of Gatekeepers in Innovator Networks," Jena Economic Research Papers 2009-058, Friedrich-Schiller-University Jena.
- Hagedoorn, John, 2002. "Inter-firm R&D partnerships: an overview of major trends and patterns since 1960," Research Policy, Elsevier, vol. 31(4), pages 477-492, May.
- Soh, Pek-Hooi, 2003. "The role of networking alliances in information acquisition and its implications for new product performance," Journal of Business Venturing, Elsevier, vol. 18(6), pages 727-744, November.
- Lim, Kwanghui, 2004. "The relationship between research and innovation in the semiconductor and pharmaceutical industries (1981-1997)," Research Policy, Elsevier, vol. 33(2), pages 287-321, March.
- Deeds, David L. & Hill, Charles W. L., 1996. "Strategic alliances and the rate of new product development: An empirical study of entrepreneurial biotechnology firms," Journal of Business Venturing, Elsevier, vol. 11(1), pages 41-55, January.
- Cameron, A. Colin & Trivedi, Pravin K., 1990. "Regression-based tests for overdispersion in the Poisson model," Journal of Econometrics, Elsevier, vol. 46(3), pages 347-364, December.
- Rodrigo Cerda, 2007. "Endogenous innovations in the pharmaceutical industry," Journal of Evolutionary Economics, Springer, vol. 17(4), pages 473-515, August.
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