IDEAS home Printed from https://ideas.repec.org/p/iza/izadps/dp15798.html
   My bibliography  Save this paper

Maternal Genetic Risk for Depression and Child Human Capital

Author

Listed:
  • Menta, Giorgia

    (LISER)

  • Lepinteur, Anthony

    (University of Luxembourg)

  • Clark, Andrew E.

    (Paris School of Economics)

  • Ghislandi, Simone

    (Bocconi University)

  • D'Ambrosio, Conchita

    (University of Luxembourg)

Abstract

We here address the causal relationship between the maternal genetic risk for depression and child human capital using UK birth-cohort data. We find that an increase of one standard deviation (SD) in the maternal polygenic risk score for depression reduces their children's cognitive and non-cognitive skill scores by 5 to 7% of a SD throughout adolescence. Our results are robust to a battery of sensitivity tests addressing, among others, concerns about pleiotropy and dynastic effects. Our Gelbach decomposition analysis suggests that the strongest mediator is genetic nurture (through maternal depression itself), with genetic inheritance playing only a marginal role.

Suggested Citation

  • Menta, Giorgia & Lepinteur, Anthony & Clark, Andrew E. & Ghislandi, Simone & D'Ambrosio, Conchita, 2022. "Maternal Genetic Risk for Depression and Child Human Capital," IZA Discussion Papers 15798, Institute of Labor Economics (IZA).
  • Handle: RePEc:iza:izadps:dp15798
    as

    Download full text from publisher

    File URL: https://docs.iza.org/dp15798.pdf
    Download Restriction: no
    ---><---

    Other versions of this item:

    References listed on IDEAS

    as
    1. Souvik Banerjee & Pinka Chatterji & Kajal Lahiri, 2017. "Effects of Psychiatric Disorders on Labor Market Outcomes: A Latent Variable Approach Using Multiple Clinical Indicators," Health Economics, John Wiley & Sons, Ltd., vol. 26(2), pages 184-205, February.
    2. Clark, Andrew E. & Lepinteur, Anthony, 2019. "The causes and consequences of early-adult unemployment: Evidence from cohort data," Journal of Economic Behavior & Organization, Elsevier, vol. 166(C), pages 107-124.
    3. Jonah B. Gelbach, 2016. "When Do Covariates Matter? And Which Ones, and How Much?," Journal of Labor Economics, University of Chicago Press, vol. 34(2), pages 509-543.
    4. James J. Heckman & John Eric Humphries & Gregory Veramendi, 2018. "Returns to Education: The Causal Effects of Education on Earnings, Health, and Smoking," Journal of Political Economy, University of Chicago Press, vol. 126(S1), pages 197-246.
    5. Volodymyr Kuleshov & Jialin Ding & Christopher Vo & Braden Hancock & Alexander Ratner & Yang Li & Christopher Ré & Serafim Batzoglou & Michael Snyder, 2019. "A machine-compiled database of genome-wide association studies," Nature Communications, Nature, vol. 10(1), pages 1-8, December.
    6. Abdel Abdellaoui & David Hugh-Jones & Loic Yengo & Kathryn E. Kemper & Michel G. Nivard & Laura Veul & Yan Holtz & Brendan P. Zietsch & Timothy M. Frayling & Naomi R. Wray & Jian Yang & Karin J. H. Ve, 2019. "Genetic correlates of social stratification in Great Britain," Nature Human Behaviour, Nature, vol. 3(12), pages 1332-1342, December.
    7. James J. Heckman & Jora Stixrud & Sergio Urzua, 2006. "The Effects of Cognitive and Noncognitive Abilities on Labor Market Outcomes and Social Behavior," Journal of Labor Economics, University of Chicago Press, vol. 24(3), pages 411-482, July.
    8. Bubonya, Melisa & Cobb-Clark, Deborah A. & Wooden, Mark, 2017. "Mental health and productivity at work: Does what you do matter?," Labour Economics, Elsevier, vol. 46(C), pages 150-165.
    9. Andrew E. Clark & Conchita D'Ambrosio & Marta Barazzetta, 2021. "Childhood circumstances and young adulthood outcomes: The role of mothers' financial problems," Health Economics, John Wiley & Sons, Ltd., vol. 30(2), pages 342-357, February.
    10. von Hinke, Stephanie & Davey Smith, George & Lawlor, Debbie A. & Propper, Carol & Windmeijer, Frank, 2016. "Genetic markers as instrumental variables," Journal of Health Economics, Elsevier, vol. 45(C), pages 131-148.
    11. Del Bono, Emilia & Kinsler, Josh & Pavan, Ronni, 2020. "Skill Formation and the Trouble with Child Non-Cognitive Skill Measures," IZA Discussion Papers 13713, Institute of Labor Economics (IZA).
    12. Andrew E. Clark & Sarah Flèche & Richard Layard & Powdthavee Nattavudh, 2018. "The Origins of Happiness: The Science of Well-Being over the Life Course," Post-Print halshs-01631510, HAL.
    13. Magnus Johannesson & David I. Laibson & Sarah E. Medland & Michelle N. Meyer & Joseph K. Pickrell & Tõnu Esko & Robert F. Krueger & Jonathan P. Beauchamp & Philipp D. Koellinger & Daniel J. Benjamin &, 2016. "Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses," Post-Print hal-02017373, HAL.
    14. Atkinson, Anthony B., 2015. "Inequality: what can be done?," LSE Research Online Documents on Economics 101810, London School of Economics and Political Science, LSE Library.
    15. Jason Fletcher, 2013. "Adolescent Depression and Adult Labor Market Outcomes," Southern Economic Journal, John Wiley & Sons, vol. 80(1), pages 26-49, July.
    16. Frederick J. Zimmerman & Wayne Katon, 2005. "Socioeconomic status, depression disparities, and financial strain: what lies behind the income‐depression relationship?," Health Economics, John Wiley & Sons, Ltd., vol. 14(12), pages 1197-1215, December.
    17. Briole, Simon & Le Forner, Hélène & Lepinteur, Anthony, 2020. "Children’s socio-emotional skills: Is there a quantity–quality trade-off?," Labour Economics, Elsevier, vol. 64(C).
    18. Thomas A. DiPrete & Casper A. P. Burik & Philipp D. Koellinger, 2018. "Genetic instrumental variable regression: Explaining socioeconomic and health outcomes in nonexperimental data," Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, vol. 115(22), pages 4970-4979, May.
    19. Victoria Baranov & Sonia Bhalotra & Pietro Biroli & Joanna Maselko, 2020. "Maternal Depression, Women's Empowerment, and Parental Investment: Evidence from a Randomized Controlled Trial," American Economic Review, American Economic Association, vol. 110(3), pages 824-859, March.
    20. Philippe Van Kerm, 2003. "Adaptive kernel density estimation," Stata Journal, StataCorp LP, vol. 3(2), pages 148-156, June.
    21. Kiernan, Kathleen E. & Huerta, Maria Carmen, 2008. "Economic deprivation, maternal depression, parenting and children's cognitive and emotional development in early childhood," LSE Research Online Documents on Economics 43720, London School of Economics and Political Science, LSE Library.
    22. Flavio Cunha & James J. Heckman, 2008. "Formulating, Identifying and Estimating the Technology of Cognitive and Noncognitive Skill Formation," Journal of Human Resources, University of Wisconsin Press, vol. 43(4).
    23. K. Paige Harden & Philipp D. Koellinger, 2020. "Using genetics for social science," Nature Human Behaviour, Nature, vol. 4(6), pages 567-576, June.
    24. von Hinke, Stephanie & Rice, Nigel & Tominey, Emma, 2022. "Mental health around pregnancy and child development from early childhood to adolescence," Labour Economics, Elsevier, vol. 78(C).
    25. Perry, Cynthia D., 2008. "Does treating maternal depression improve child health management The case of pediatric asthma," Journal of Health Economics, Elsevier, vol. 27(1), pages 157-173, January.
    26. Joel Becker & Casper A. P. Burik & Grant Goldman & Nancy Wang & Hariharan Jayashankar & Michael Bennett & Daniel W. Belsky & Richard Karlsson Linnér & Rafael Ahlskog & Aaron Kleinman & David A. Hinds , 2021. "Resource profile and user guide of the Polygenic Index Repository," Nature Human Behaviour, Nature, vol. 5(12), pages 1744-1758, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Andrew E. Clark & Conchita D'Ambrosio & Simone Ghislandi & Anthony Lepinteur & Giorgia Menta, 2021. "Maternal depression and child human capital: a genetic instrumental-variable approach," CEP Discussion Papers dp1749, Centre for Economic Performance, LSE.
    2. Uta Bolt & Eric French & Jamie Hentall-MacCuish & Cormac O'Dea, 2021. "The intergenerational elasticity of earnings: exploring the mechanisms," IFS Working Papers W21/07, Institute for Fiscal Studies.
    3. Thomas Buser & Rafael Ahlskog & Magnus Johannesson & Sven Oskarsson, 2022. "Occupational sorting on genes," Tinbergen Institute Discussion Papers 22-062/I, Tinbergen Institute, revised 29 Mar 2023.
    4. Pereira, Rita & Biroli, Pietro & von hinke, stephanie & Van Kippersluis, Hans & Galama, Titus & Rietveld, Niels & Thom, Kevin, 2022. "Gene-Environment Interplay in the Social Sciences," OSF Preprints d96z3, Center for Open Science.
    5. Michael J. Kottelenberg & Steven F. Lehrer, 2019. "How Skills and Parental Valuation of Education Influence Human Capital Acquisition and Early Labor Market Return to Human Capital in Canada," Journal of Labor Economics, University of Chicago Press, vol. 37(S2), pages 735-778.
    6. Briole, Simon & Le Forner, Hélène & Lepinteur, Anthony, 2020. "Children’s socio-emotional skills: Is there a quantity–quality trade-off?," Labour Economics, Elsevier, vol. 64(C).
    7. James J. Heckman & Chase O. Corbin, 2016. "Capabilities and Skills," Journal of Human Development and Capabilities, Taylor & Francis Journals, vol. 17(3), pages 342-359, July.
    8. Chikako Yamauchi, 2010. "Parental Investment in Children: Differential Pathways of Parental Education and Mental Health," The Economic Record, The Economic Society of Australia, vol. 86(273), pages 210-226, June.
    9. La Ferrara, Eliana & Carlana, Michela & Pinotti, Paolo, 2017. "Goals and Gaps: Educational Careers of Immigrant Children," CEPR Discussion Papers 12538, C.E.P.R. Discussion Papers.
    10. Glewwe, Paul & Song, Yang & Zou, Xianqiang, 2022. "Labor market outcomes, cognitive skills, and noncognitive skills in rural China," Journal of Economic Behavior & Organization, Elsevier, vol. 193(C), pages 294-311.
    11. Hélène Le Forner, 2021. "Formation of Children’s Cognitive and Socio-Emotional Skills: Is All Parental Time Equal?," AMSE Working Papers 2117, Aix-Marseille School of Economics, France.
    12. Mohitosh Kejriwal & Xiaoxiao Li & Linh Nguyen & Evan Totty, 2024. "The efficacy of ability proxies for estimating the returns to schooling: A factor model‐based evaluation," Journal of Applied Econometrics, John Wiley & Sons, Ltd., vol. 39(1), pages 3-21, January.
    13. Mónica Hernández-Alava & Gurleen Popli, 2017. "Children’s Development and Parental Input: Evidence From the UK Millennium Cohort Study," Demography, Springer;Population Association of America (PAA), vol. 54(2), pages 485-511, April.
    14. Amin, Vikesh & Flores, Carlos A. & Flores-Lagunes, Alfonso, 2020. "The impact of BMI on mental health: Further evidence from genetic markers," Economics & Human Biology, Elsevier, vol. 38(C).
    15. James J. Heckman & Bridget Galaty & Haihan Tian, 2023. "The Economic Approach to Personality, Character and Virtue," NBER Working Papers 31258, National Bureau of Economic Research, Inc.
    16. Silvia H. Barcellos & Leandro Carvalho & Patrick Turley, 2021. "The Effect of Education on the Relationship between Genetics, Early-Life Disadvantages, and Later-Life SES," NBER Working Papers 28750, National Bureau of Economic Research, Inc.
    17. Sevim, Dilek & Baranov, Victoria & Bhalotra, Sonia & Maselko, Joanna & Biroli, Pietro, 2023. "Trajectories of Early Childhood Skill Development and Maternal Mental Health," CAGE Online Working Paper Series 674, Competitive Advantage in the Global Economy (CAGE).
    18. Szabó-Morvai, Ágnes & Kiss, Hubert János, 2022. "Különböznek-e a roma és nem roma diákok nem kognitív képességeikben? [Do Roma and non-Roma students differ in their non-cognitive abilities?]," Közgazdasági Szemle (Economic Review - monthly of the Hungarian Academy of Sciences), Közgazdasági Szemle Alapítvány (Economic Review Foundation), vol. 0(11), pages 1433-1456.
    19. Breitkopf, Laura & Chowdhury, Shyamal K. & Priyam, Shambhavi & Schildberg-Hörisch, Hannah & Sutter, Matthias, 2020. "Do economic preferences of children predict behavior?," DICE Discussion Papers 342, Heinrich Heine University Düsseldorf, Düsseldorf Institute for Competition Economics (DICE).
    20. Greta Morando & Lucinda Platt, 2022. "The Impact of Centre‐based Childcare on Non‐cognitive Skills of Young Children," Economica, London School of Economics and Political Science, vol. 89(356), pages 908-946, October.

    More about this item

    Keywords

    maternal depression; human capital; ALSPAC;
    All these keywords.

    JEL classification:

    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • J24 - Labor and Demographic Economics - - Demand and Supply of Labor - - - Human Capital; Skills; Occupational Choice; Labor Productivity

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:iza:izadps:dp15798. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Holger Hinte (email available below). General contact details of provider: https://edirc.repec.org/data/izaaade.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.