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The Evolution of the Pharmaceutical Industry Over the Past 50 Years: A Personal Reflection

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  • Henry Grabowski

Abstract

The pharmaceutical industry has an outstanding record of innovative performance over the past 50 years. The R&D process has become more knowledge-based and a market for innovation has emerged between research start-ups, development-stage firms, and the larger, multinational companies. At the same time, R&D costs have increased several fold over time and generic products now dominate many traditional therapeutic areas. The current challenge for the industry is to discover new therapies for chronic diseases with high unmet needs like Alzheimer's disease and various auto-immune diseases and cancers that afflict an increasingly aging population. Recent advances in molecular biology and related fields provide a scientific foundation to undertake these R&D efforts, although the time path and outcomes remain subject to many risks and uncertainties.

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  • Henry Grabowski, 2011. "The Evolution of the Pharmaceutical Industry Over the Past 50 Years: A Personal Reflection," International Journal of the Economics of Business, Taylor & Francis Journals, vol. 18(2), pages 161-176.
    • Handle: RePEc:taf:ijecbs:v:18:y:2011:i:2:p:161-176
    DOI: 10.1080/13571516.2011.584421
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    References listed on IDEAS

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    1. Ernst Berndt & Murray Aitken, 2011. "Brand Loyalty, Generic Entry and Price Competition in Pharmaceuticals in the Quarter Century after the 1984 Waxman-Hatch Legislation," International Journal of the Economics of Business, Taylor & Francis Journals, vol. 18(2), pages 177-201.
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    Cited by:

    1. Li, Lei & Li, Dan & Goerzen, Anthony & Shi, Weilei (Stone), 2018. "What and how do SMEs gain by going international? A longitudinal investigation of financial and intellectual resource growth," Journal of World Business, Elsevier, vol. 53(6), pages 817-834.
    2. Yong J. Yoon, 2017. "Buchanan on increasing returns and anticommons," Constitutional Political Economy, Springer, vol. 28(3), pages 270-285, September.

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