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Soft governance against superbugs: How effective is the international regime on antimicrobial resistance?

Author

Listed:
  • Mirko Heinzel

    (University of Glasgow
    London School of Economics and Political Science)

  • Mathias Koenig-Archibugi

    (London School of Economics and Political Science)

Abstract

Antimicrobial resistance (AMR) and the declining effectiveness of antibiotic medicines due to misuse are among the biggest threats to global health and a major challenge for global governance in this century. Since drug-resistant bacteria spread easily across borders, government policies that exacerbate or mitigate AMR affect other countries. International organizations and governments addressed the global public good of maintaining antimicrobial protection by creating a soft governance regime largely devoid of legally binding rules and enforcement mechanisms. This article presents a cross-national empirical assessment of the effectiveness of the international AMR regime combining novel data on national action plans and data on antibiotic consumption in 191 countries between 2000 and 2018. We find that the regime sets ambitious goals and achieves broad participation, substantial implementation, and meaningful change in the use of antibiotics. The involvement of the largest consumers of antibiotics has been crucial for both effectiveness and equity.

Suggested Citation

  • Mirko Heinzel & Mathias Koenig-Archibugi, 2024. "Soft governance against superbugs: How effective is the international regime on antimicrobial resistance?," The Review of International Organizations, Springer, vol. 19(2), pages 345-374, April.
    • Handle: RePEc:spr:revint:v:19:y:2024:i:2:d:10.1007_s11558-023-09510-7
    DOI: 10.1007/s11558-023-09510-7
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    as
    1. Clément de Chaisemartin & Xavier D'Haultfœuille, 2020. "Two-Way Fixed Effects Estimators with Heterogeneous Treatment Effects," American Economic Review, American Economic Association, vol. 110(9), pages 2964-2996, September.
    2. Todd Sandler & Daniel G Arce M, 2002. "A conceptual framework for understanding global and transnational public goods for health," Fiscal Studies, Institute for Fiscal Studies, vol. 23(2), pages 195-222, June.
    3. Colgan, Jeff D. & Green, Jessica F. & Hale, Thomas N., 2021. "Asset Revaluation and the Existential Politics of Climate Change," International Organization, Cambridge University Press, vol. 75(2), pages 586-610, February.
    4. Oliver Westerwinter, 2021. "Transnational public-private governance initiatives in world politics: Introducing a new dataset," The Review of International Organizations, Springer, vol. 16(1), pages 137-174, January.
    5. Emily Oster, 2019. "Unobservable Selection and Coefficient Stability: Theory and Evidence," Journal of Business & Economic Statistics, Taylor & Francis Journals, vol. 37(2), pages 187-204, April.
    6. Carl Henrik Knutsen & Andreas Kotsadam & Eivind Hammersmark Olsen & Tore Wig, 2017. "Mining and Local Corruption in Africa," American Journal of Political Science, John Wiley & Sons, vol. 61(2), pages 320-334, April.
    7. Ahmed, Syud Amer & Barış, Enis & Go, Delfin S. & Lofgren, Hans & Osorio-Rodarte, Israel & Thierfelder, Karen, 2018. "Assessing the global poverty effects of antimicrobial resistance," World Development, Elsevier, vol. 111(C), pages 148-160.
    8. Tobias Böhmelt & Edita Butkutė, 2018. "The self-selection of democracies into treaty design: insights from international environmental agreements," International Environmental Agreements: Politics, Law and Economics, Springer, vol. 18(3), pages 351-367, June.
    9. Isaksson, Ann-Sofie & Kotsadam, Andreas, 2018. "Chinese aid and local corruption," Journal of Public Economics, Elsevier, vol. 159(C), pages 146-159.
    10. Blackwell, Matthew & Glynn, Adam N., 2018. "How to Make Causal Inferences with Time-Series Cross-Sectional Data under Selection on Observables," American Political Science Review, Cambridge University Press, vol. 112(4), pages 1067-1082, November.
    11. Olivier Rubin & Louise Munkholm, 2022. "Isomorphic dynamics in national action plans on antimicrobial resistance," Public Administration & Development, Blackwell Publishing, vol. 42(2), pages 142-153, May.
    12. Felicity Vabulas & Duncan Snidal, 2013. "Organization without delegation: Informal intergovernmental organizations (IIGOs) and the spectrum of intergovernmental arrangements," The Review of International Organizations, Springer, vol. 8(2), pages 193-220, June.
    13. Tallberg, Jonas, 2002. "Paths to Compliance: Enforcement, Management, and the European Union," International Organization, Cambridge University Press, vol. 56(3), pages 609-643, July.
    14. Magnus Lundgren & Theresa Squatrito & Jonas Tallberg, 2018. "Stability and change in international policy-making: A punctuated equilibrium approach," The Review of International Organizations, Springer, vol. 13(4), pages 547-572, December.
    15. Abbott, Kenneth W. & Keohane, Robert O. & Moravcsik, Andrew & Slaughter, Anne-Marie & Snidal, Duncan, 2000. "The Concept of Legalization," International Organization, Cambridge University Press, vol. 54(3), pages 401-419, July.
    16. Frid-Nielsen, Snorre Sylvester & Rubin, Olivier & Baekkeskov, Erik, 2019. "The state of social science research on antimicrobial resistance," Social Science & Medicine, Elsevier, vol. 242(C).
    17. Dai, Xinyuan, 2005. "Why Comply? The Domestic Constituency Mechanism," International Organization, Cambridge University Press, vol. 59(2), pages 363-398, April.
    18. Scott Barrett, 2008. "Climate treaties and the imperative of enforcement," Oxford Review of Economic Policy, Oxford University Press and Oxford Review of Economic Policy Limited, vol. 24(2), pages 239-258, Summer.
    19. Martin, Lisa L., 1992. "Interests, power, and multilateralism," International Organization, Cambridge University Press, vol. 46(4), pages 765-792, October.
    20. Goodman-Bacon, Andrew, 2021. "Difference-in-differences with variation in treatment timing," Journal of Econometrics, Elsevier, vol. 225(2), pages 254-277.
    21. Francesca Parente, 2022. "Settle or litigate? Consequences of institutional design in the Inter-American system of human rights protection," The Review of International Organizations, Springer, vol. 17(1), pages 39-61, January.
    22. Felicity Vabulas & Duncan Snidal, 2021. "Cooperation under autonomy: Building and analyzing the Informal Intergovernmental Organizations 2.0 dataset," Journal of Peace Research, Peace Research Institute Oslo, vol. 58(4), pages 859-869, July.
    23. Rene S. Hendriksen & Patrick Munk & Patrick Njage & Bram Bunnik & Luke McNally & Oksana Lukjancenko & Timo Röder & David Nieuwenhuijse & Susanne Karlsmose Pedersen & Jette Kjeldgaard & Rolf S. Kaas & , 2019. "Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
    24. Ramanan Laxminarayan, 2016. "Trans-boundary commons in infectious diseases," Oxford Review of Economic Policy, Oxford University Press and Oxford Review of Economic Policy Limited, vol. 32(1), pages 88-101.
    25. Scott H. Podolsky, 2018. "The evolving response to antibiotic resistance (1945–2018)," Palgrave Communications, Palgrave Macmillan, vol. 4(1), pages 1-8, December.
    26. Wolfgang Buchholz & Todd Sandler, 2021. "Global Public Goods: A Survey," Journal of Economic Literature, American Economic Association, vol. 59(2), pages 488-545, June.
    27. Downs, George W. & Rocke, David M. & Barsoom, Peter N., 1996. "Is the good news about compliance good news about cooperation?," International Organization, Cambridge University Press, vol. 50(3), pages 379-406, July.
    28. Imai, Kosuke & Kim, In Song, 2021. "On the Use of Two-Way Fixed Effects Regression Models for Causal Inference with Panel Data," Political Analysis, Cambridge University Press, vol. 29(3), pages 405-415, July.
    29. Abbott, Kenneth W. & Snidal, Duncan, 2000. "Hard and Soft Law in International Governance," International Organization, Cambridge University Press, vol. 54(3), pages 421-456, July.
    30. Martin Köppel & Detlef F. Sprinz, 2019. "Do Binding Beat Nonbinding Agreements? Regulating International Water Quality," Journal of Conflict Resolution, Peace Science Society (International), vol. 63(8), pages 1860-1888, September.
    31. Manuel Oechslin & Elias Steiner, 2022. "Statistical capacity and corrupt bureaucracies," The Review of International Organizations, Springer, vol. 17(1), pages 143-174, January.
    32. Jean‐Frédéric Morin & Hugo Dobson & Claire Peacock & Miriam Prys‐Hansen & Abdoulaye Anne & Louis Bélanger & Peter Dietsch & Judit Fabian & John Kirton & Raffaele Marchetti & Simone Romano & Miranda Sc, 2019. "How Informality Can Address Emerging Issues: Making the Most of the G7," Global Policy, London School of Economics and Political Science, vol. 10(2), pages 267-273, May.
    33. Thomas Bernauer & Anna Kalbhenn & Vally Koubi & Gabriele Spilker, 2013. "Is there a “Depth versus Participation” dilemma in international cooperation?," The Review of International Organizations, Springer, vol. 8(4), pages 477-497, December.
    34. Thomas Hale, 2020. "Catalytic Cooperation," Global Environmental Politics, MIT Press, vol. 20(4), pages 73-98, Autumn.
    35. Morse, Julia C., 2019. "Blacklists, Market Enforcement, and the Global Regime to Combat Terrorist Financing," International Organization, Cambridge University Press, vol. 73(3), pages 511-545, July.
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