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A Quantitative Analysis of Undisclosed Conflicts of Interest in Pharmacology Textbooks

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  • Brian J Piper
  • Hassenet M Telku
  • Drew A Lambert

Abstract

Background: Disclosure of potential conflicts of interest (CoI) is a standard practice for many biomedical journals but not for educational materials. The goal of this investigation was to determine whether the authors of pharmacology textbooks have undisclosed financial CoIs and to identify author characteristics associated with CoIs. Methods and Findings: The presence of potential CoIs was evaluated by submitting author names (N = 403; 36.3% female) to a patent database (Google Scholar) as well as a database that reports on the compensation ($USD) received from 15 pharmaceutical companies (ProPublica’s Dollars for Docs). All publications (N = 410) of the ten highest compensated authors from 2009 to 2013 and indexed in Pubmed were also examined for disclosure of additional companies that the authors received research support, consulted, or served on speaker’s bureaus. A total of 134 patents had been awarded (Maximum = 18/author) to textbook authors. Relative to DiPiro’s Pharmacotherapy: A Pathophysiologic Approach, contributors to Goodman and Gilman’s Pharmacological Basis of Therapeutics and Katzung’s Basic and Clinical Pharmacology were more frequently patent holders (OR = 6.45, P 1 patent (OR = 0.15, P

Suggested Citation

  • Brian J Piper & Hassenet M Telku & Drew A Lambert, 2015. "A Quantitative Analysis of Undisclosed Conflicts of Interest in Pharmacology Textbooks," PLOS ONE, Public Library of Science, vol. 10(7), pages 1-9, July.
    • Handle: RePEc:plo:pone00:0133261
    DOI: 10.1371/journal.pone.0133261
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    References listed on IDEAS

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    1. Kevin P Weinfurt & Damon M Seils & Janice P Tzeng & Li Lin & Kevin A Schulman & Robert M Califf, 2008. "Consistency of Financial Interest Disclosures in the Biomedical Literature: The Case of Coronary Stents," PLOS ONE, Public Library of Science, vol. 3(5), pages 1-7, May.
    2. Daylian M. Cain & George Loewenstein & Don A. Moore, 2005. "The Dirt on Coming Clean: Perverse Effects of Disclosing Conflicts of Interest," The Journal of Legal Studies, University of Chicago Press, vol. 34(1), pages 1-25, January.
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