IDEAS home Printed from https://ideas.repec.org/a/gam/jsusta/v13y2021i17p9763-d625830.html
   My bibliography  Save this article

51 Flavors: Regional Resource Configurations and Foreign Multinational Market Entry in the U.S. Biopharmaceutical Industry

Author

Listed:
  • Roberto S. Santos

    (Manning School of Business, University of Massachusetts Lowell, One University Avenue, Lowell, MA 01854, USA)

  • Denise R. Dunlap

    (Manning School of Business, University of Massachusetts Lowell, One University Avenue, Lowell, MA 01854, USA)

Abstract

Creating a sustainable regional economy requires not only attracting new local ventures, but also foreign multinationals. In this regard, understanding which resources are influential in market entry decisions is crucial given that there are different resource needs between developed (DMNE) and emerging market (EMNE) multinationals. Answering calls for more neo-configurational studies in the literature, our study uses a fuzzy-set qualitative comparative analysis (fsQCA) approach to examine foreign multinational entry decisions in 51 regions of the U.S. We constructed a novel dataset comprised of 3287 foreign firms from 61 countries and territories operating in the biopharmaceutical industry. We find that there are substantial differences in the configuration of resources that attract DMNEs and EMNEs to regions. The resource configurations in our models account for over 80% of the factors influencing DMNE and EMNE market entry location decisions. Some resources played a more important role in these decisions, such as FDI stocks, cluster size, and manufacturing intensity. Our findings show that EMNEs seek out regions with a greater abundance of different resources than DMNEs. This study provides practical implications for firms entering foreign markets as well as for policy makers who want to attract these firms to bolster their regional economic development.

Suggested Citation

  • Roberto S. Santos & Denise R. Dunlap, 2021. "51 Flavors: Regional Resource Configurations and Foreign Multinational Market Entry in the U.S. Biopharmaceutical Industry," Sustainability, MDPI, vol. 13(17), pages 1-17, August.
  • Handle: RePEc:gam:jsusta:v:13:y:2021:i:17:p:9763-:d:625830
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/2071-1050/13/17/9763/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/2071-1050/13/17/9763/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Meuer, Johannes & Rupietta, Christian & Backes-Gellner, Uschi, 2015. "Layers of co-existing innovation systems," Research Policy, Elsevier, vol. 44(4), pages 888-910.
    2. Philip Bodman & Thanh Le, 2013. "Assessing the roles that absorptive capacity and economic distance play in the foreign direct investment-productivity growth nexus," Applied Economics, Taylor & Francis Journals, vol. 45(8), pages 1027-1039, March.
    3. Riccardo Crescenzi & Simona Iammarino, 2017. "Global investments and regional development trajectories: the missing links," Regional Studies, Taylor & Francis Journals, vol. 51(1), pages 97-115, January.
    4. Gilding, Michael & Brennecke, Julia & Bunton, Vikki & Lusher, Dean & Molloy, Peter L. & Codoreanu, Alex, 2020. "Network failure: Biotechnology firms, clusters and collaborations far from the world superclusters," Research Policy, Elsevier, vol. 49(2).
    5. Kalle Pajunen, 2008. "Institutions and inflows of foreign direct investment: a fuzzy-set analysis," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 39(4), pages 652-669, June.
    6. Chen, Maggie Xiaoyang & Moore, Michael O., 2010. "Location decision of heterogeneous multinational firms," Journal of International Economics, Elsevier, vol. 80(2), pages 188-199, March.
    7. Caves, Richard E, 1974. "Causes of Direct Investment: Foreign Firms' Shares in Canadian and United Kingdom Manufacturing Industries," The Review of Economics and Statistics, MIT Press, vol. 56(3), pages 279-293, August.
    8. Ekaterina Turkina & Ari Van Assche, 2018. "Global connectedness and local innovation in industrial clusters," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 49(6), pages 706-728, August.
    9. Walter Kuemmerle, 1999. "The Drivers of Foreign Direct Investment into Research and Development: An Empirical Investigation," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 30(1), pages 1-24, March.
    10. Ciravegna, Luciano & Kuivalainen, Olli & Kundu, Sumit K. & Lopez, Luis E., 2018. "The antecedents of early internationalization: A configurational perspective," International Business Review, Elsevier, vol. 27(6), pages 1200-1212.
    11. Zoltán J. Ács & Pontus Braunerhjelm & David B. Audretsch & Bo Carlsson, 2015. "The knowledge spillover theory of entrepreneurship," Chapters, in: Global Entrepreneurship, Institutions and Incentives, chapter 7, pages 129-144, Edward Elgar Publishing.
    12. Simona Iammarino, 2018. "FDI and regional development policy," Journal of International Business Policy, Palgrave Macmillan, vol. 1(3), pages 157-183, December.
    13. J. Myles Shaver & Fredrick Flyer, 2000. "Agglomeration economies, firm heterogeneity, and foreign direct investment in the United States," Strategic Management Journal, Wiley Blackwell, vol. 21(12), pages 1175-1193, December.
    14. Li, Xiaoqing & Quan, Rose & Stoian, Maria-Cristina & Azar, Goudarz, 2018. "Do MNEs from developed and emerging economies differ in their location choice of FDI? A 36-year review," International Business Review, Elsevier, vol. 27(5), pages 1089-1103.
    15. Johanna Mair & Ignasi Marti & Marc Ventresca, 2012. "Building Inclusive Markets in Rural Bangladesh : How Intermediaries Work Institutional Voids," Post-Print hal-02276707, HAL.
    16. Edward L. Glaeser & Sari Pekkala Kerr & William R. Kerr, 2015. "Entrepreneurship and Urban Growth: An Empirical Assessment with Historical Mines," The Review of Economics and Statistics, MIT Press, vol. 97(2), pages 498-520, May.
    17. Crescenzi, Riccardo & Gagliardi, Luisa & Iammarino, Simona, 2015. "Foreign multinationals and domestic innovation: Intra-industry effects and firm heterogeneity," Research Policy, Elsevier, vol. 44(3), pages 596-609.
    18. David Ahlstrom & Garry D. Bruton, 2006. "Venture Capital in Emerging Economies: Networks and Institutional Change," Entrepreneurship Theory and Practice, , vol. 30(2), pages 299-320, March.
    19. Castellani, Davide & Pieri, Fabio, 2013. "R&D offshoring and the productivity growth of European regions," Research Policy, Elsevier, vol. 42(9), pages 1581-1594.
    20. Thomas Greckhamer, 2016. "CEO compensation in relation to worker compensation across countries: The configurational impact of country-level institutions," Strategic Management Journal, Wiley Blackwell, vol. 37(4), pages 793-815, April.
    21. Jindra, Björn & Hassan, Sohaib S. & Cantner, Uwe, 2016. "What does location choice reveal about knowledge-seeking strategies of emerging market multinationals in the EU?," International Business Review, Elsevier, vol. 25(1), pages 204-220.
    22. John H Dunning, 1998. "Location and the Multinational Enterprise: A Neglected Factor?," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 29(1), pages 45-66, March.
    23. Casper, Steven, 2007. "How do technology clusters emerge and become sustainable?: Social network formation and inter-firm mobility within the San Diego biotechnology cluster," Research Policy, Elsevier, vol. 36(4), pages 438-455, May.
    24. Rebecca Henderson & Iain Cockburn, 1994. "Measuring Competence? Exploring Firm Effects in Pharmaceutical Research," Strategic Management Journal, Wiley Blackwell, vol. 15(S1), pages 63-84, December.
    25. Delgado, Mercedes & Porter, Michael E. & Stern, Scott, 2014. "Clusters, convergence, and economic performance," Research Policy, Elsevier, vol. 43(10), pages 1785-1799.
    26. Kyle C. Longest & Stephen Vaisey, 2008. "fuzzy: A program for performing qualitative comparative analyses (QCA) in Stata," Stata Journal, StataCorp LP, vol. 8(1), pages 79-104, February.
    27. Johanna Mair & Ignasi Marti & Marc Ventresca, 2012. "Building Inclusive Markets in Rural Bangladesh : How Intermediaries Work Institutional Voids," Post-Print hal-02312706, HAL.
    28. Kolympiris, Christos & Kalaitzandonakes, Nicholas & Miller, Douglas, 2011. "Spatial collocation and venture capital in the US biotechnology industry," Research Policy, Elsevier, vol. 40(9), pages 1188-1199.
    29. Giuliani, Elisa & Arza, Valeria, 2009. "What drives the formation of 'valuable' university-industry linkages?: Insights from the wine industry," Research Policy, Elsevier, vol. 38(6), pages 906-921, July.
    30. Ekaterina Turkina & Ari Van Assche, 2018. "Global Connectedness and Local Innovation in Industrial Clusters," CIRANO Working Papers 2018s-12, CIRANO.
    31. Denise R. Dunlap & Roberto S. Santos, 2021. "Storming the Beachhead: An Examination of Developed and Emerging Market Multinational Strategic Location Decisions in the U.S," JRFM, MDPI, vol. 14(7), pages 1-15, July.
    32. Keld Laursen & Toke Reichstein & Ammon Salter, 2011. "Exploring the Effect of Geographical Proximity and University Quality on University-Industry Collaboration in the United Kingdom," Regional Studies, Taylor & Francis Journals, vol. 45(4), pages 507-523.
    33. Anna Lamin & Grigorios Livanis, 2013. "Agglomeration, catch-up and the liability of foreignness in emerging economies," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 44(6), pages 579-606, August.
    34. Jason Owen-Smith & Walter W. Powell, 2004. "Knowledge Networks as Channels and Conduits: The Effects of Spillovers in the Boston Biotechnology Community," Organization Science, INFORMS, vol. 15(1), pages 5-21, February.
    35. Martin R Schneider & Conrad Schulze-Bentrop & Mihai Paunescu, 2010. "Mapping the institutional capital of high-tech firms: A fuzzy-set analysis of capitalist variety and export performance," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 41(2), pages 246-266, February.
    36. Roberto S. Santos & Lingling Qin, 2019. "Risk Capital and Emerging Technologies: Innovation and Investment Patterns Based on Artificial Intelligence Patent Data Analysis," JRFM, MDPI, vol. 12(4), pages 1-24, December.
    37. Simon X. B. Zhao & David W. H. Wong & David W. S. Wong & Y. P. Jiang, 2020. "Ever‐transient FDI and ever‐polarizing regional development: Revisiting conventional theories of regional development in the context of China, Southeast and South Asia," Growth and Change, Wiley Blackwell, vol. 51(1), pages 338-361, March.
    38. Stav Fainshmidt & Michael A Witt & Ruth V Aguilera & Alain Verbeke, 2020. "The contributions of qualitative comparative analysis (QCA) to international business research," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 51(4), pages 455-466, June.
    39. Juan Alcácer & Wilbur Chung, 2014. "Location strategies for agglomeration economies," Strategic Management Journal, Wiley Blackwell, vol. 35(12), pages 1749-1761, December.
    40. Kangmin Wu & Yang Wang & Yuyao Ye & Hongou Zhang & Guangqing Huang, 2019. "Relationship Between the Built Environment and the Location Choice of High-Tech Firms: Evidence from the Pearl River Delta," Sustainability, MDPI, vol. 11(13), pages 1-21, July.
    41. Aharonson, Barak S. & Baum, Joel A.C. & Plunket, Anne, 2008. "Inventive and uninventive clusters: The case of Canadian biotechnology," Research Policy, Elsevier, vol. 37(6-7), pages 1108-1131, July.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Denise R. Dunlap & Roberto S. Santos, 2021. "Storming the Beachhead: An Examination of Developed and Emerging Market Multinational Strategic Location Decisions in the U.S," JRFM, MDPI, vol. 14(7), pages 1-15, July.
    2. Pengfei Li & Harald Bathelt, 2018. "Location strategy in cluster networks," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 49(8), pages 967-989, October.
    3. Marina Papanastassiou & Robert Pearce & Antonello Zanfei, 2020. "Changing perspectives on the internationalization of R&D and innovation by multinational enterprises: A review of the literature," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 51(4), pages 623-664, June.
    4. Nidthida Lin, 2020. "Designing Global Sourcing Strategy for Cost Savings and Innovation: A Configurational Approach," Management International Review, Springer, vol. 60(5), pages 723-753, October.
    5. Kolympiris, Christos & Kalaitzandonakes, Nicholas & Miller, Douglas, 2014. "Public funds and local biotechnology firm creation," Research Policy, Elsevier, vol. 43(1), pages 121-137.
    6. Ascani, Andrea & Bettarelli, Luca & Resmini, Laura & Balland, Pierre-Alexandre, 2020. "Global networks, local specialisation and regional patterns of innovation," Research Policy, Elsevier, vol. 49(8).
    7. Wonsang Ryu & Thomas H. Brush & Joonhyung Bae, 2023. "How agglomeration affects alliance governance and innovation performance: The role of cluster size," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 44(1), pages 297-310, January.
    8. Haake, Claus-Jochen & Schneider, Martin R., 2024. "Playing games with QCA: The Banzhaf index as a context-sensitive measure of explanatory power in international management," Journal of International Management, Elsevier, vol. 30(2).
    9. Stav Fainshmidt & Michael A Witt & Ruth V Aguilera & Alain Verbeke, 2020. "The contributions of qualitative comparative analysis (QCA) to international business research," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 51(4), pages 455-466, June.
    10. Claus-Jochen Haake & Martin Schneider, 2022. "Playing games with QCA: Measuring the explanatory power of single conditions with the Banzhaf index," Working Papers CIE 150, Paderborn University, CIE Center for International Economics.
    11. Ekaterina Turkina & Boris Oreshkin, 2021. "The Impact of Co-Inventor Networks on Smart Cleantech Innovation: The Case of Montreal Agglomeration," Sustainability, MDPI, vol. 13(13), pages 1-17, June.
    12. Maximilian Buchholz & Harald Bathelt & John A. Cantwell, 2020. "Income divergence and global connectivity of U.S. urban regions," Journal of International Business Policy, Palgrave Macmillan, vol. 3(3), pages 229-248, September.
    13. Shameen Prashantham & Sumelika Bhattacharyya, 2020. "MNE–SME co-innovation in peripheral regions," Journal of International Business Policy, Palgrave Macmillan, vol. 3(2), pages 134-153, June.
    14. Claver-Cortés, Enrique & Marco-Lajara, Bartolome & Manresa-Marhuenda, Encarnación & García-Lillo, F. & Seva-Larrosa, Pedro, 2017. "Location Decisions and Agglomeration Economies: Domestic and Foreign Companies," INVESTIGACIONES REGIONALES - Journal of REGIONAL RESEARCH, Asociación Española de Ciencia Regional, issue 39, pages 99-135.
    15. Ito, Keiko & Ikeuchi, Kenta & Criscuolo, Chiara & Timmis, Jonathan & Bergeaud, Antonin, 2023. "Global value chains and domestic innovation," Research Policy, Elsevier, vol. 52(3).
    16. Maximilian Buchholz & Harald Bathelt & John A. Cantwell, 0. "Income divergence and global connectivity of U.S. urban regions," Journal of International Business Policy, Palgrave Macmillan, vol. 0, pages 1-20.
    17. Jaideep Anand & Gerald McDermott & Ram Mudambi & Rajneesh Narula, 2021. "Innovation in and from emerging economies: New insights and lessons for international business research," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 52(4), pages 545-559, June.
    18. Carlino, Gerald & Kerr, William R., 2015. "Agglomeration and Innovation," Handbook of Regional and Urban Economics, in: Gilles Duranton & J. V. Henderson & William C. Strange (ed.), Handbook of Regional and Urban Economics, edition 1, volume 5, chapter 0, pages 349-404, Elsevier.
    19. Lipeng Gary Ge & Cuili Qian & Jiatao Li, 2019. "Mimicry, Knowledge Spillover and Expatriate Assignment Strategy in Overseas Subsidiaries," Management International Review, Springer, vol. 59(6), pages 981-1007, December.
    20. Richter, Nicole Franziska & Hauff, Sven, 2022. "Necessary conditions in international business research–Advancing the field with a new perspective on causality and data analysis," Journal of World Business, Elsevier, vol. 57(5).

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jsusta:v:13:y:2021:i:17:p:9763-:d:625830. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.