An Empirical Model of Learning under Ambiguity: The Case of Clinical Trials
In this paper, I present an empirical model of learning under ambiguity in the context of clinical trials. Patients are concern with learning the treatment effect of the experimental drug, but face the ambiguity of random group assignment. A two dimensional Bayesian model of learning is proposed to capture patients�beliefs on the treatment effect and group assignment. These beliefs are then used to predict patient attrition in clinical trials. Patient learning is demonstrated to be slower when taking into account group ambiguity. In addition, the model corrects for attrition bias in the estimated treatment effect.
|Date of creation:||03 Apr 2008|
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- James Heckman & Neil Hohmann & Jeffrey Smith & Michael Khoo, 2000.
"Substitution and Dropout Bias in Social Experiments: A Study of an Influential Social Experiment,"
The Quarterly Journal of Economics,
Oxford University Press, vol. 115(2), pages 651-694.
- James Heckman & Neil Hohmann & Jeffrey Smith, 1998. "Substitution and Dropout Bias in Social Experiments: A Study of an Influential Social Experiment," UWO Department of Economics Working Papers 9819, University of Western Ontario, Department of Economics.
- Gregory S. Crawford & Matthew Shum, 2005. "Uncertainty and Learning in Pharmaceutical Demand," Econometrica, Econometric Society, vol. 73(4), pages 1137-1173, 07.
- Hausman, Jerry A & Wise, David A, 1979. "Attrition Bias in Experimental and Panel Data: The Gary Income Maintenance Experiment," Econometrica, Econometric Society, vol. 47(2), pages 455-73, March.
- Steven Stern, 1994.
"Two Dynamic Discrete Choice Estimation Problems and Simulation Method Solutions,"
Virginia Economics Online Papers
389, University of Virginia, Department of Economics.
- Stern, Steven, 1994. "Two Dynamic Discrete Choice Estimation Problems and Simulation Method Solutions," The Review of Economics and Statistics, MIT Press, vol. 76(4), pages 695-702, November.
- Daniel A. Ackerberg, 2003. "Advertising, learning, and consumer choice in experience good markets: an empirical examination," International Economic Review, Department of Economics, University of Pennsylvania and Osaka University Institute of Social and Economic Research Association, vol. 44(3), pages 1007-1040, 08.
- Tat Y. Chan & Barton H. Hamilton, 2006. "Learning, Private Information, and the Economic Evaluation of Randomized Experiments," Journal of Political Economy, University of Chicago Press, vol. 114(6), pages 997-1040, December.
- Berkovec, James & Stern, Steven, 1991. "Job Exit Behavior of Older Men," Econometrica, Econometric Society, vol. 59(1), pages 189-210, January.
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