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Association of a Genetic Risk Score with BMI along the Life-Cycle: Evidence from Several US Cohorts

Author

Listed:
  • Sanz-de-Galdeano, Anna

    (Universidad de Alicante)

  • Terskaya, Anastasia

    (University of Barcelona)

  • Upegui, Angie

    (Universidad de Alicante)

Abstract

We use data from the The National Longitudinal Study of Adolescent to Adult Health and from the Health and Retirement Study to explore how the the effect of individuals' genetic predisposition to higher BMI —measured by BMI polygenic scores— changes over the life-cycle for several cohorts. We find that the effect of BMI polygenic scores on BMI increases significantly as teenagers transition into adulthood (using the Add Health cohort, born 1974-83). However, this is not the case for individuals aged 55+ who were born in earlier HRS cohorts (1931-53), whose life-cycle pattern of genetic influence on BMI is remarkably stable as they move into old-age.

Suggested Citation

  • Sanz-de-Galdeano, Anna & Terskaya, Anastasia & Upegui, Angie, 2020. "Association of a Genetic Risk Score with BMI along the Life-Cycle: Evidence from Several US Cohorts," IZA Discussion Papers 13671, IZA Network @ LISER.
    • Handle: RePEc:iza:izadps:dp13671
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    References listed on IDEAS

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    1. Daniel J. Benjamin & David Cesarini & Christopher F. Chabris & Edward L. Glaeser & David I. Laibson & Vilmundur Guðnason & Tamara B. Harris & Lenore J. Launer & Shaun Purcell & Albert Vernon Smith & M, 2012. "The Promises and Pitfalls of Genoeconomics," Annual Review of Economics, Annual Reviews, vol. 4(1), pages 627-662, July.
      • Grankvist, Alexander & Benjamin, Daniel J. & Harris, Tamara B. & Launer, Lenore J. & Smith, Albert Vernon & Johannesson, Magnus & Atwood, Craig S. & Hebert, Benjamin Michael & Hultman, Christina M. & , 2012. "The Promises and Pitfalls of Genoeconomics," Scholarly Articles 10137000, Harvard University Department of Economics.
    2. repec:nas:journl:v:115:y:2018:p:e9765-e9772 is not listed on IDEAS
    3. Sanz-de-Galdeano, Anna & Terskaya, Anastasia, 2019. "Sibling Differences in Educational Polygenic Scores: How Do Parents React?," IZA Discussion Papers 12375, IZA Network @ LISER.
    4. Anna Zajacova & Sarah Burgard, 2013. "Healthier, Wealthier, and Wiser: A Demonstration of Compositional Changes in Aging Cohorts Due to Selective Mortality," Population Research and Policy Review, Springer;Southern Demographic Association (SDA), vol. 32(3), pages 311-324, June.
    5. David M. Cutler & Edward L. Glaeser & Jesse M. Shapiro, 2003. "Why Have Americans Become More Obese?," Journal of Economic Perspectives, American Economic Association, vol. 17(3), pages 93-118, Summer.
    6. Giorgio Brunello & Pierre-Carl Michaud & Anna Sanz-de-Galdeano, 2008. "The Rise in Obesity Across the Atlantic An Economic Perspective," Working Papers WR-586, RAND Corporation.
    7. Schaefer, D.R. & Simpkins, S.D., 2014. "Using social network analysis to clarify the role of obesity in selection of adolescent friends," American Journal of Public Health, American Public Health Association, vol. 104(7), pages 1223-1229.
    8. Cawley, John, 2015. "An economy of scales: A selective review of obesity's economic causes, consequences, and solutions," Journal of Health Economics, Elsevier, vol. 43(C), pages 244-268.
    9. Sergio Firpo & Nicole M. Fortin & Thomas Lemieux, 2009. "Unconditional Quantile Regressions," Econometrica, Econometric Society, vol. 77(3), pages 953-973, May.
    10. John Cawley, 2004. "The Impact of Obesity on Wages," Journal of Human Resources, University of Wisconsin Press, vol. 39(2).
    11. Brunello, Giorgio & Sanz-de-Galdeano, Anna & Terskaya, Anastasia, 2020. "Not only in my genes: The effects of peers’ genotype on obesity," Journal of Health Economics, Elsevier, vol. 72(C).
    12. Petri Böckerman & John Cawley & Jutta Viinikainen & Terho Lehtimäki & Suvi Rovio & Ilkka Seppälä & Jaakko Pehkonen & Olli Raitakari, 2019. "The effect of weight on labor market outcomes: An application of genetic instrumental variables," Health Economics, John Wiley & Sons, Ltd., vol. 28(1), pages 65-77, January.
    13. Jeffrey R Kling & Jeffrey B Liebman & Lawrence F Katz, 2007. "Experimental Analysis of Neighborhood Effects," Econometrica, Econometric Society, vol. 75(1), pages 83-119, January.
    14. Jason Boardman & Benjamin Domingue & Casey Blalock & Brett Haberstick & Kathleen Harris & Matthew McQueen, 2014. "Is the Gene-Environment Interaction Paradigm Relevant to Genome-Wide Studies? The Case of Education and Body Mass Index," Demography, Springer;Population Association of America (PAA), vol. 51(1), pages 119-139, February.
    15. Brunello, Giorgio & D'Hombres, Beatrice, 2007. "Does body weight affect wages?: Evidence from Europe," Economics & Human Biology, Elsevier, vol. 5(1), pages 1-19, March.
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    JEL classification:

    • I1 - Health, Education, and Welfare - - Health
    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality

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