IDEAS home Printed from https://ideas.repec.org/a/wly/jpamgt/v24y2005i2p249-272.html
   My bibliography  Save this article

Anti-depressants, suicide, and drug regulation

Author

Listed:
  • Jens Ludwig

    (Georgetown University)

  • Dave E. Marcotte

    (University of Maryland, Baltimore County)

Abstract

Policymakers are increasingly concerned that a relatively new class of anti-depressant drugs, selective serotonin re-uptake inhibitors (SSRI), may increase the risk of suicide for at least some patients, particularly children. Prior randomized trials are not informative on this question because of small sample sizes and other limitations. Using variation across countries over time in SSRI sales and suicide, we find that an increase of one pill per capita (a 13 percent increase over 1999 levels) is associated with a 2.5 percent reduction in suicide rates, a relationship that is more pronounced for adults than for children. Our findings suggest that expanding access to SSRIs for adults may be a cost-effective way to save lives, although policymakers are right to remain cautious about pediatric use of SSRIs. © 2005 by the Association for Public Policy Analysis and Management

Suggested Citation

  • Jens Ludwig & Dave E. Marcotte, 2005. "Anti-depressants, suicide, and drug regulation," Journal of Policy Analysis and Management, John Wiley & Sons, Ltd., vol. 24(2), pages 249-272.
  • Handle: RePEc:wly:jpamgt:v:24:y:2005:i:2:p:249-272
    DOI: 10.1002/pam.20089
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1002/pam.20089
    File Function: Link to full text; subscription required
    Download Restriction: no

    References listed on IDEAS

    as
    1. Morrall, John F, III, 2003. "Saving Lives: A Review of the Record," Journal of Risk and Uncertainty, Springer, vol. 27(3), pages 221-237, December.
    2. Philipson, Tomas, 2000. "Economic epidemiology and infectious diseases," Handbook of Health Economics,in: A. J. Culyer & J. P. Newhouse (ed.), Handbook of Health Economics, edition 1, volume 1, chapter 33, pages 1761-1799 Elsevier.
    3. Viscusi, W Kip & Aldy, Joseph E, 2003. "The Value of a Statistical Life: A Critical Review of Market Estimates throughout the World," Journal of Risk and Uncertainty, Springer, vol. 27(1), pages 5-76, August.
    4. White, Halbert, 1982. "Maximum Likelihood Estimation of Misspecified Models," Econometrica, Econometric Society, vol. 50(1), pages 1-25, January.
    5. Dahlberg, Matz & Lundin, Douglas, 2005. "Antidepressants and the Suicide Rate: Is There Really a Connection?," Working Paper Series 2005:4, Uppsala University, Department of Economics.
    6. repec:reg:rpubli:282 is not listed on IDEAS
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ludwig, Jens & Marcotte, Dave E. & Norberg, Karen, 2009. "Anti-depressants and suicide," Journal of Health Economics, Elsevier, vol. 28(3), pages 659-676, May.
    2. Kristy Parkinson & Joseph Price & Kosali Simon & Sharon Tennyson, 2014. "The influence of FDA advisory information and black box warnings on individual use of prescription antidepressants," Review of Economics of the Household, Springer, vol. 12(4), pages 771-790, December.
    3. Cuellar, Alison Evans & Markowitz, Sara, 2007. "Medicaid policy changes in mental health care and their effect on mental health outcomes," Health Economics, Policy and Law, Cambridge University Press, vol. 2(01), pages 23-49, January.
    4. Dahlberg, Matz & Lundin, Douglas, 2005. "Antidepressants and the Suicide Rate: Is There Really a Connection?," Working Paper Series 2005:4, Uppsala University, Department of Economics.
    5. Katolik, Aleksandra & Oswald, Andrew J., 2017. "Antidepressants for Economists and Business-School Researchers: An Introduction and Review," CAGE Online Working Paper Series 338, Competitive Advantage in the Global Economy (CAGE).
    6. Markowitz, Sara & Cuellar, Alison, 2007. "Antidepressants and youth: Healing or harmful?," Social Science & Medicine, Elsevier, vol. 64(10), pages 2138-2151, May.
    7. Manoj K. Pandey & Charanjit Kaur, 2009. "Investigating Suicidal Trend and its Economic Determinants: Evidence from India," ASARC Working Papers 2009-08, The Australian National University, Australia South Asia Research Centre.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:wly:jpamgt:v:24:y:2005:i:2:p:249-272. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Wiley-Blackwell Digital Licensing) or (Christopher F. Baum). General contact details of provider: http://www3.interscience.wiley.com/journal/34787/home .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.