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A serially correlated gamma frailty model for longitudinal count data


  • Robin Henderson


A Poisson-gamma model is introduced to account for between-subjects heterogeneity and within-subjects serial correlation occurring in longitudinal count data. The model extends the usual time-constant shared frailty approach to allow time-varying serially correlated gamma frailty whilst retaining standard marginal assumptions. A composite likelihood approach to estimation and testing for serial correlation is proposed. The work is motivated by a clinical trial on patient-controlled analgesia where the number of analgesic doses taken by hospital patients in successive time intervals following abdominal surgery is recorded. Copyright Biometrika Trust 2003, Oxford University Press.

Suggested Citation

  • Robin Henderson, 2003. "A serially correlated gamma frailty model for longitudinal count data," Biometrika, Biometrika Trust, vol. 90(2), pages 355-366, June.
  • Handle: RePEc:oup:biomet:v:90:y:2003:i:2:p:355-366

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    Cited by:

    1. Varin, Cristiano & Host, Gudmund & Skare, Oivind, 2005. "Pairwise likelihood inference in spatial generalized linear mixed models," Computational Statistics & Data Analysis, Elsevier, vol. 49(4), pages 1173-1191, June.
    2. Bhat, Chandra R. & Sener, Ipek N. & Eluru, Naveen, 2010. "A flexible spatially dependent discrete choice model: Formulation and application to teenagers' weekday recreational activity participation," Transportation Research Part B: Methodological, Elsevier, vol. 44(8-9), pages 903-921, September.
    3. Michael L. Pennell & David B. Dunson, 2006. "Bayesian Semiparametric Dynamic Frailty Models for Multiple Event Time Data," Biometrics, The International Biometric Society, vol. 62(4), pages 1044-1052, December.
    4. van den Berg, Gerard J. & Effraimidis, Georgios, 2014. "Dependence Measures in Bivariate Gamma Frailty Models," IZA Discussion Papers 8083, Institute of Labor Economics (IZA).
    5. Li Liu & Liming Xiang, 2014. "Semiparametric estimation in generalized linear mixed models with auxiliary covariates: A pairwise likelihood approach," Biometrics, The International Biometric Society, vol. 70(4), pages 910-919, December.
    6. Yang Lu, 2018. "Dynamic Frailty Count Process in Insurance: A Unified Framework for Estimation, Pricing, and Forecasting," Post-Print halshs-02418950, HAL.
    7. De Oliveira, Victor, 2013. "Hierarchical Poisson models for spatial count data," Journal of Multivariate Analysis, Elsevier, vol. 122(C), pages 393-408.
    8. Cristiano Varin, 2008. "On composite marginal likelihoods," AStA Advances in Statistical Analysis, Springer;German Statistical Society, vol. 92(1), pages 1-28, February.
    9. Emilio Augusto Coelho-Barros & Jorge Alberto Achcar & Josmar Mazucheli, 2010. "Longitudinal Poisson modeling: an application for CD4 counting in HIV-infected patients," Journal of Applied Statistics, Taylor & Francis Journals, vol. 37(5), pages 865-880.
    10. Papageorgiou, Ioulia & Moustaki, Irini, 2018. "Sampling of pairs in pairwise likelihood estimation for latent variable models with categorical observed variables," LSE Research Online Documents on Economics 87592, London School of Economics and Political Science, LSE Library.
    11. Deng Ling & Moore Dirk F., 2009. "Composite Likelihood Modeling of Neighboring Site Correlations of DNA Sequence Substitution Rates," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 8(1), pages 1-20, January.

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