Exact and Approximate Stepdown Methods for Multiple Hypothesis Testing
Consider the problem of testing k hypotheses simultaneously. In this paper, we discuss finite and large sample theory of stepdown methods that provide control of the familywise error rate (FWE). In order to improve upon the Bonferroni method or Holm's (1979) stepdown method, Westfall and Young (1993) make e ective use of resampling to construct stepdown methods that implicitly estimate the dependence structure of the test statistics. However, their methods depend on an assumption called subset pivotality. The goal of this paper is to construct general stepdown methods that do not require such an assumption. In order to accomplish this, we take a close look at what makes stepdown procedures work, and a key component is a monotonicity requirement of critical values. By imposing such monotonicity on estimated critical values (which is not an assumption on the model but an assumption on the method), it is demonstrated that the problem of constructing a valid multiple test procedure which controls the FWE can be reduced to the problem of contructing a single test which controls the usual probability of a Type 1 error. This reduction allows us to draw upon an enormous resampling literature as a general means of test contruction.
(This abstract was borrowed from another version of this item.)
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
As the access to this document is restricted, you may want to look for a different version under "Related research" (further below) or search for a different version of it.
Volume (Year): 100 (2005)
Issue (Month): (March)
|Contact details of provider:|| Web page: http://www.amstat.org/publications/jasa/index.cfm?fuseaction=main|
|Order Information:||Web: http://www.amstat.org/publications/index.html|
References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- G. Hommel, 1986. "Multiple test procedures for arbitrary dependence structures," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 33(1), pages 321-336, December.
- Delgado, Miguel A. & Rodriguez-Poo, Juan M. & Wolf, Michael, 2001.
"Subsampling inference in cube root asymptotics with an application to Manski's maximum score estimator,"
Elsevier, vol. 73(2), pages 241-250, November.
- Delgado, Miguel A. & Wolf, Michael & Rodríguez Poo, Juan M., 2000. "Subsampling inference in cube root asymptotics with an application to manski's maximum score estimator," DES - Working Papers. Statistics and Econometrics. WS 10110, Universidad Carlos III de Madrid. Departamento de Estadística.
When requesting a correction, please mention this item's handle: RePEc:bes:jnlasa:v:100:y:2005:p:94-108. See general information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Christopher F. Baum)
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If references are entirely missing, you can add them using this form.
If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.
Please note that corrections may take a couple of weeks to filter through the various RePEc services.