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Exploration and exploitation in innovation systems: The case of pharmaceutical biotechnology

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  1. Guan, Jiancheng & Liu, Na, 2016. "Exploitative and exploratory innovations in knowledge network and collaboration network: A patent analysis in the technological field of nano-energy," Research Policy, Elsevier, vol. 45(1), pages 97-112.
  2. Arman Avadikyan & Gilles Lambert & Christophe Lerch, 2016. "A Multi-Level Perspective on Ambidexterity: The Case of a Synchrotron Research Facility," Working Papers of BETA 2016-44, Bureau d'Economie Théorique et Appliquée, UDS, Strasbourg.
  3. Stephen Roper & Helen Xia, 2014. "Unpacking open innovation: Absorptive capacity, exploratory and exploitative openness and the growth of entrepreneurial biopharmaceutical firms," Research Papers 0019, Enterprise Research Centre.
  4. Tina Wolf & Uwe Cantner & Holger Graf & Michael Rothgang, 2019. "Cluster ambidexterity towards exploration and exploitation: strategies and cluster management," The Journal of Technology Transfer, Springer, vol. 44(6), pages 1840-1866, December.
  5. Gautam Ahuja & Curba Morris Lampert & Vivek Tandon, 2014. "Paradigm-Changing vs. Paradigm-Deepening Innovation: How Firm Scope Influences Firm Technological Response to Shocks," Organization Science, INFORMS, vol. 25(3), pages 653-669, June.
  6. Wang, Tao, 2023. "Toward an understanding of innovation failure: The timing of failure experience," Technovation, Elsevier, vol. 125(C).
  7. Elodie Gardet & Caroline Danièle Mothe, 2011. "The dynamics of coordination in innovation networks," Post-Print hal-00919245, HAL.
  8. Laure Ambroise & Céline Bérard & Isabelle Prim-Allaz, 2020. "Performance implications of exploration and exploitation in SMEs: The mediating role of interaction orientation," Post-Print halshs-02570780, HAL.
  9. Michael Fritsch & Martina Kauffeld-Monz, 2010. "The impact of network structure on knowledge transfer: an application of social network analysis in the context of regional innovation networks," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 44(1), pages 21-38, February.
  10. Tödtling, Franz & Trippl, Michaela & Gabain, Joshua von, 2006. "Clusterentwicklung und -politik im Biotechnologiesektor Wien im Kontext internationaler Erfahrungen," SRE-Discussion Papers 2006/02, WU Vienna University of Economics and Business.
  11. Jane Bjørn Vedel & Olga Kokshagina, 2021. "How firms undertake organizational changes to shift to more-exploratory strategies: A process perspective," Post-Print hal-02943926, HAL.
  12. Vanhaverbeke, Wim & Li, Ying & Van de Vrande, Vareska, 2009. "The dual role of external corporate venturing in technological exploration," MPRA Paper 26488, University Library of Munich, Germany, revised 2010.
  13. Chang, Ching-Wen & Yamanaka, Takayuki & Kano, Shingo, 2019. "An enforced loop-out knowledge flow facilitates industry competition: Learning from the pharmaceutical and genetically modified seed industries," Technovation, Elsevier, vol. 79(C), pages 11-24.
  14. Chen, Shih-Hsin & Lin, Wei-Ting, 2018. "Analyzing determinants for promoting emerging technology through intermediaries by using a DANP-based MCDA framework," Technological Forecasting and Social Change, Elsevier, vol. 131(C), pages 94-110.
  15. Beverly B. Tyler & Turanay Caner, 2016. "New product introductions below aspirations, slack and R&D alliances: A behavioral perspective," Strategic Management Journal, Wiley Blackwell, vol. 37(5), pages 896-910, May.
  16. Magnani, Giovanna & Zucchella, Antonella, 2021. "Portfolios of learning in entrepreneurial internationalisation," Journal of International Management, Elsevier, vol. 27(2).
  17. Sébastien Brion & Caroline Mothe & Maréva Sabatier, 2010. "The Impact Of Organisational Context And Competences On Innovation Ambidexterity," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 14(02), pages 151-178.
  18. Messeni Petruzzelli, Antonio, 2019. "Trading knowledge for status: Conceptualizing R&D alliance formation to achieve ambidexterity," Technological Forecasting and Social Change, Elsevier, vol. 145(C), pages 36-42.
  19. Ingo Stiller & Arjen Witteloostuijn & Bart Cambré, 2022. "Determinants of radical drug innovation: a systematic literature review," Management Review Quarterly, Springer, vol. 72(4), pages 967-1016, December.
  20. Huber, Franz, 2013. "Knowledge-sourcing of R&D workers in different job positions: Contextualising external personal knowledge networks," Research Policy, Elsevier, vol. 42(1), pages 167-179.
  21. Vanhaverbeke, W.P.M. & Beerkens, B.E. & Duysters, G.M., 2003. "Explorative and exploitative learning strategies in technology-based alliance networks," Working Papers 03.22, Eindhoven Center for Innovation Studies.
  22. García Granero,Ana & Vega-Jurado,Jaider, 2012. "External knowledge sourcing and innovation performance: the role of managerial practices," INGENIO (CSIC-UPV) Working Paper Series 201201, INGENIO (CSIC-UPV), revised 21 May 2012.
  23. Shukla, Dhirendra Mani & Mital, Amita & Qureshi, Israr & Wang, Taiyuan, 2020. "Valuation effects of alliance portfolio expansion speed and strength: Evidence from high-tech firms," Journal of Business Research, Elsevier, vol. 113(C), pages 370-383.
  24. Vedel, Jane Bjørn & Kokshagina, Olga, 2021. "How firms undertake organizational changes to shift to more-exploratory strategies: A process perspective," Research Policy, Elsevier, vol. 50(1).
  25. Zhang, Zhu & Lyles, Marjorie A. & Wu, Changqi, 2020. "The stock market performance of exploration-oriented and exploitation-oriented cross-border mergers and acquisitions: Evidence from emerging market enterprises," International Business Review, Elsevier, vol. 29(4).
  26. Flemming Sørensen & Jan Mattsson, 2016. "Speeding Up Innovation: Building Network Structures For Parallel Innovation," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 20(02), pages 1-30, February.
  27. Villalba Morales, María Luisa & Ruiz Castañeda, Walter & Robledo Velásquez, Jorge, 2023. "Configuration of inclusive innovation systems: Function, agents and capabilities," Research Policy, Elsevier, vol. 52(7).
  28. Varghese P. George, 2014. "Technological Exploration And Market Exploitation In Interfirm Alliances," International Journal of Management and Marketing Research, The Institute for Business and Finance Research, vol. 7(2), pages 1-14.
  29. BELDERBOS, René & GILSING, Victor & SUZUKI, Shinya, 2015. "Direct And Mediated Ties To Universities: ‘Scientific’ Absorptive Capacity And Innovation Performance Of Pharmaceutical Firms," Discussion paper series 2015-06, Hitotsubashi Institute for Advanced Study, Hitotsubashi University.
  30. Hewitt-Dundas, Nola & Gkypali, Areti & Roper, Stephen, 2019. "Does learning from prior collaboration help firms to overcome the ‘two-worlds’ paradox in university-business collaboration?," Research Policy, Elsevier, vol. 48(5), pages 1310-1322.
  31. Annika Lorenz & Michael Raven & Knut Blind, 2019. "The role of standardization at the interface of product and process development in biotechnology," The Journal of Technology Transfer, Springer, vol. 44(4), pages 1097-1133, August.
  32. Migliaccio Mirella & Francesca Rivetti, 2013. "Client Knowledge Opportunities for a Small Software Firm," Symphonya. Emerging Issues in Management, University of Milano-Bicocca, issue 1 Global .
  33. Simon, Fanny & Tellier, Albéric, 2011. "How do actors shape social networks during the process of new product development?," European Management Journal, Elsevier, vol. 29(5), pages 414-430.
  34. Jiří Blažek & Pavla Žížalová, 2010. "The Biotechnology Industry in the Prague Metropolitan Region: A Cluster within a Fragmented Innovation System?," Environment and Planning C, , vol. 28(5), pages 887-904, October.
  35. Liu, Jiali & Yu, Jiang & Chen, Feng & Zhang, Yaokun & Li, Bo, 2022. "How latecomers strategically respond to global-local resources and leverage local ecosystems: Evidence from China's integrated circuit design firms," Technological Forecasting and Social Change, Elsevier, vol. 183(C).
  36. Venugopal, Aparna & Krishnan, T.N. & Upadhyayula, Rajesh Srinivas & Kumar, Manish, 2020. "Finding the microfoundations of organizational ambidexterity - Demystifying the role of top management behavioural integration," Journal of Business Research, Elsevier, vol. 106(C), pages 1-11.
  37. Véronique Favre-Bonté & Elodie Gardet & Catherine Thevenard-Puthod, 2019. "How Types of Destination Influence Tourism Innovation Networks?," Post-Print hal-02145911, HAL.
  38. Xun Wang, 2023. "Stock market, credit market, and heterogeneous innovations," International Review of Finance, International Review of Finance Ltd., vol. 23(1), pages 103-129, March.
  39. Markus M. Bugge & Sara Øiestad, 2015. "The Micro-foundations of Regional Branching-the Case of Digitization of Publishing," European Planning Studies, Taylor & Francis Journals, vol. 23(4), pages 764-784, April.
  40. Victor Gilsing & Rudi Bekkers & Bodas Freitas & Marianne van der Steen, 2011. "Differences in technology transfer between science-based and development based industries: transfer mechanisms and barriers," Grenoble Ecole de Management (Post-Print) hal-01487500, HAL.
  41. Jiang Wei & Minfei Zhou & Mark Greeven & Hongyan Qu, 2016. "Economic governance, dual networks and innovative learning in five Chinese industrial clusters," Asia Pacific Journal of Management, Springer, vol. 33(4), pages 1037-1074, December.
  42. Romasanta, Angelo K.S. & van der Sijde, Peter & de Esch, Iwan J.P., 2022. "Absorbing knowledge from an emerging field: The role of interfacing by proponents in big pharma," Technovation, Elsevier, vol. 110(C).
  43. Chung, Chao-chen, 2013. "Government, policy-making and the development of innovation system: The cases of Taiwanese pharmaceutical biotechnology policies (2000–2008)," Research Policy, Elsevier, vol. 42(5), pages 1053-1071.
  44. Alessia Pisoni & Alberto Onetti & Luciano Fratocchi & Marco Talaia, 2010. "Managing R&D activities in the Italian red biotech industry. A comparison between Italian independent firms and multinational companies," Economics and Quantitative Methods qf1003, Department of Economics, University of Insubria.
  45. Dittrich, Koen & Duysters, Geert & de Man, Ard-Pieter, 2007. "Strategic repositioning by means of alliance networks: The case of IBM," Research Policy, Elsevier, vol. 36(10), pages 1496-1511, December.
  46. Wang, Yuandi & Sutherland, Dylan & Ning, Lutao & Pan, Xin, 2015. "The evolving nature of China's regional innovation systems: Insights from an exploration–exploitation approach," Technological Forecasting and Social Change, Elsevier, vol. 100(C), pages 140-152.
  47. Anokhin, Sergey Alexander & Morgan, Todd, 2023. "CEO duality and tenure, and the adoption of goal ambidexterity in corporate venture capital," Journal of Business Venturing Insights, Elsevier, vol. 19(C).
  48. René Belderbos & Martin Carree & Boris Lokshin & Juan Fernández Sastre, 2015. "Inter-temporal patterns of R&D collaboration and innovative performance," The Journal of Technology Transfer, Springer, vol. 40(1), pages 123-137, February.
  49. Elodie Gardet & Caroline Mothe, 2009. "Les mécanismes de garantie au sein d’un réseau d’alliances développant un projet d’innovation," Revue Finance Contrôle Stratégie, revues.org, vol. 12(3), pages 131-160, September.
  50. Brion, Sébastien & Mothe, Caroline & Sabatier, Mareva, 2007. "What impacts more on innovation : Organizational context or individual competences ?," MPRA Paper 10595, University Library of Munich, Germany.
  51. Gupeng Zhang & Xiao Wang & Hongbo Duan, 2020. "Obscure but important: examining the indirect effects of alliance networks in exploratory and exploitative innovation paradigms," Scientometrics, Springer;Akadémiai Kiadó, vol. 124(3), pages 1745-1764, September.
  52. Claudimar Pereira Da Veiga & Cássia Rita Pereira Da Veiga & Jansen Maia Del Corso & Wesley Vieira Da Silva, 2015. "Dengue Vaccines: A Perspective from the Point of View of Intellectual Property," IJERPH, MDPI, vol. 12(8), pages 1-21, August.
  53. Catherine Beaudry, 2011. "Collaboration and contracting out versus funding and support – Impact on the propensity to patent of Canadian biotechnology firms 1999-2005," CIRANO Working Papers 2011s-62, CIRANO.
  54. Angelo Kenneth S. Romasanta & Peter Sijde & Jacqueline Muijlwijk-Koezen, 2020. "Innovation in pharmaceutical R&D: mapping the research landscape," Scientometrics, Springer;Akadémiai Kiadó, vol. 125(3), pages 1801-1832, December.
  55. Ad van den Oord & Arjen van Witteloostuijn, 2018. "A multi-level model of emerging technology: An empirical study of the evolution of biotechnology from 1976 to 2003," PLOS ONE, Public Library of Science, vol. 13(5), pages 1-27, May.
  56. Gilsing, V.A. & van Burg, E. & Romme, A.G.L., 2010. "Policy principles for the creation and success of corporate and academic spin-offs," Other publications TiSEM 4f828c53-0ac2-4ea7-9f90-4, Tilburg University, School of Economics and Management.
  57. Montserrat Boronat-Navarro & Alexandra García-Joerger, 2019. "Ambidexterity, Alliances and Environmental Management System Adoption in Spanish Hotels," Sustainability, MDPI, vol. 11(20), pages 1-16, October.
  58. Santiago, Fernando & Alcorta, Ludovico, 2012. "Human resource management for learning through knowledge exploitation and knowledge exploration: Pharmaceuticals in Mexico," Structural Change and Economic Dynamics, Elsevier, vol. 23(4), pages 530-546.
  59. Farzaneh, Mandana & Wilden, Ralf & Afshari, Leila & Mehralian, Gholamhossein, 2022. "Dynamic capabilities and innovation ambidexterity: The roles of intellectual capital and innovation orientation," Journal of Business Research, Elsevier, vol. 148(C), pages 47-59.
  60. Fanny Simon & Albéric Tellier, 2011. "How do actors shape social networks during the process of new product development?," Post-Print hal-01572294, HAL.
  61. Xiaoli Li & Kun Li & Hao Zhou, 2022. "Impact of Inventor’s Cooperation Network on Ambidextrous Innovation in Chinese AI Enterprises," Sustainability, MDPI, vol. 14(16), pages 1-21, August.
  62. K D S Fernald & H P G Pennings & J F van den Bosch & H R Commandeur & E Claassen, 2017. "The moderating role of absorptive capacity and the differential effects of acquisitions and alliances on Big Pharma firms' innovation performance," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-22, February.
  63. Anindya Ghosh & Thomas Klueter, 2022. "The Role of Frictions due to Top Management in Alliance Termination Decisions: Insights from Established Bio‐Pharmaceutical Firms," Journal of Management Studies, Wiley Blackwell, vol. 59(5), pages 1315-1353, July.
  64. Yuval Kalish & Amalya L. Oliver, 2022. "Reducing the cost of knowledge exchange in consortia: network analyses of multiple relations," The Journal of Technology Transfer, Springer, vol. 47(3), pages 775-803, June.
  65. Lichtenthaler, Ulrich & Ernst, Holger, 2007. "Developing reputation to overcome the imperfections in the markets for knowledge," Research Policy, Elsevier, vol. 36(1), pages 37-55, February.
  66. Bernal, Pilar & Carree, Martin & Lokshin, Boris, 2022. "Knowledge spillovers, R&D partnerships and innovation performance," Technovation, Elsevier, vol. 115(C).
  67. McCarthy, Killian J & Aalbers, Hendrik Leendert, 2022. "Alliance-to-acquisition transitions: The technological performance implications of acquiring one's alliance partners," Research Policy, Elsevier, vol. 51(6).
  68. Klueter, Thomas & Monteiro, L. Felipe & Dunlap, Denise R., 2017. "Standard vs. partnership-embedded licensing: Attention and the relationship between licensing and product innovations," Research Policy, Elsevier, vol. 46(9), pages 1629-1643.
  69. Massimo Colombo & Liliana Doganova & Evila Piva & Diego D’Adda & Philippe Mustar, 2015. "Hybrid alliances and radical innovation: the performance implications of integrating exploration and exploitation," The Journal of Technology Transfer, Springer, vol. 40(4), pages 696-722, August.
  70. Szulanski, Gabriel & Jensen, Robert J., 2008. "Growing through copying: The negative consequences of innovation on franchise network growth," Research Policy, Elsevier, vol. 37(10), pages 1732-1741, December.
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