A Few Special Cases: Scientific Creativity and Network Dynamics in the Field of Rare Diseases
We develop a model of scientific creativity and test it in the field of rare diseases. Our model is based on the results of an in-depth case study of the Rett syndrome. Archival analysis, bibliometric techniques and expert surveys are combined with network analysis to identify the most creative scientists. First, alternative measures of generative and combinatorial creativity are compared. Then, we generalize our results and present a stochastic model of socio-semantic network evolution. The model predictions are tested with multiple networks of rare disease specialties. We find that new scientific collaborations among experts in a field enhance combinatorial creativity. Instead, high entry rates of novices are negatively related to generative creativity. By extending the set of useful concepts, creative scientists gain in centrality. At the same time, by increasing their centrality in the scientific community, scientists can replicate and generalize their results, thus contributing to a scientific paradigm.
|Date of creation:||Mar 2011|
|Date of revision:||24 May 2011|
|Contact details of provider:|| Postal: |
Web page: http://www.unitn.it/disa
More information through EDIRC
|Order Information:|| Postal: DISA Università degli Studi di Trento via Inama, 5 I-38122 Trento TN Italy|
Web: http://www.unitn.it/disa Email:
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Jason Owen-Smith & Massimo Riccaboni & Fabio Pammolli & Walter W. Powell, 2002.
"A Comparison of U.S. and European University-Industry Relations in the Life Sciences,"
INFORMS, vol. 48(1), pages 24-43, January.
- Jason Owen-Smith & Massimo Riccaboni & Fabio Pammolli & Walter W. Powell, 2001. "A Comparison of U.S. And European University-Industry Relations in the Life Sciences," LEM Papers Series 2001/03, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
- Owen-Smith, Jason & Riccaboni, Massimo & Pammolli, Fabio & Powell, Walter W., 2002. "A Comparison of U.S. and European University-Industry Relations in the Life Sciences," MPRA Paper 15963, University Library of Munich, Germany.
- Lambiotte, R. & Panzarasa, P., 2009. "Communities, knowledge creation, and information diffusion," Journal of Informetrics, Elsevier, vol. 3(3), pages 180-190.
- Rinia, E. J. & van Leeuwen, Th. N. & van Vuren, H. G. & van Raan, A. F. J., 1998. "Comparative analysis of a set of bibliometric indicators and central peer review criteria: Evaluation of condensed matter physics in the Netherlands," Research Policy, Elsevier, vol. 27(1), pages 95-107, May.
- Lane, David, et al, 1996.
"Choice and Action,"
Journal of Evolutionary Economics,
Springer, vol. 6(1), pages 43-76, February.
- Martin L. Weitzman, 1998.
The Quarterly Journal of Economics,
MIT Press, vol. 113(2), pages 331-360, May.
- Weitzman, Martin L., 1998. "Recombinant Growth," Scholarly Articles 3708468, Harvard University Department of Economics.
- Martin L. Weitzman, 1995. "Recombinant Growth," Harvard Institute of Economic Research Working Papers 1722, Harvard - Institute of Economic Research.
- Nigel Gilbert, 1997. "A Simulation of the Structure of Academic Science," Sociological Research Online, Sociological Research Online, vol. 2(2), pages 3.
- Orsenigo, L. & Pammolli, F. & Riccaboni, Massimo, 2001. "Technological change and network dynamics: Lessons from the pharmaceutical industry," Research Policy, Elsevier, vol. 30(3), pages 485-508, March.
- David W. Galenson & Bruce A. Weinberg, 2001. "Creating Modern Art: The Changing Careers of Painters in France from Impressionism to Cubism," American Economic Review, American Economic Association, vol. 91(4), pages 1063-1071, September.
- Chen, Chaomei & Chen, Yue & Horowitz, Mark & Hou, Haiyan & Liu, Zeyuan & Pellegrino, Donald, 2009. "Towards an explanatory and computational theory of scientific discovery," Journal of Informetrics, Elsevier, vol. 3(3), pages 191-209.
- Bruckner, E, et al, 1996. "Nonlinear Stochastic Effects of Substitution--An Evolutionary Approach," Journal of Evolutionary Economics, Springer, vol. 6(1), pages 1-30, February.
When requesting a correction, please mention this item's handle: RePEc:trt:disawp:2011/03. See general information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Roberto Gabriele)
If references are entirely missing, you can add them using this form.