A Few Special Cases: Scientific Creativity and Network Dynamics in the Field of Rare Diseases
We develop a model of scientific creativity and test it in the field of rare diseases. Our model is based on the results of an in-depth case study of the Rett syndrome. Archival analysis, bibliometric techniques and expert surveys are combined with network analysis to identify the most creative scientists. First, alternative measures of generative and combinatorial creativity are compared. Then, we generalize our results and present a stochastic model of socio-semantic network evolution. The model predictions are tested with multiple networks of rare disease specialties. We find that new scientific collaborations among experts in a field enhance combinatorial creativity. Instead, high entry rates of novices are negatively related to generative creativity. By extending the set of useful concepts, creative scientists gain in centrality. At the same time, by increasing their centrality in the scientific community, scientists can replicate and generalize their results, thus contributing to a scientific paradigm.
|Date of creation:||Mar 2011|
|Date of revision:||24 May 2011|
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- Jason Owen-Smith & Massimo Riccaboni & Fabio Pammolli & Walter W. Powell, 2001.
"A Comparison of U.S. And European University-Industry Relations in the Life Sciences,"
LEM Papers Series
2001/03, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
- Jason Owen-Smith & Massimo Riccaboni & Fabio Pammolli & Walter W. Powell, 2002. "A Comparison of U.S. and European University-Industry Relations in the Life Sciences," Management Science, INFORMS, vol. 48(1), pages 24-43, January.
- Owen-Smith, Jason & Riccaboni, Massimo & Pammolli, Fabio & Powell, Walter W., 2002. "A Comparison of U.S. and European University-Industry Relations in the Life Sciences," MPRA Paper 15963, University Library of Munich, Germany.
- Lambiotte, R. & Panzarasa, P., 2009. "Communities, knowledge creation, and information diffusion," Journal of Informetrics, Elsevier, vol. 3(3), pages 180-190.
- Martin L. Weitzman, 1998.
The Quarterly Journal of Economics,
Oxford University Press, vol. 113(2), pages 331-360.
- Weitzman, Martin L., 1998. "Recombinant Growth," Scholarly Articles 3708468, Harvard University Department of Economics.
- Martin L. Weitzman, 1995. "Recombinant Growth," Harvard Institute of Economic Research Working Papers 1722, Harvard - Institute of Economic Research.
- David Lane & Franco Malerba & Robert Maxfield & Luigi Orsenigo, 1995.
"Choice and Action,"
95-01-004, Santa Fe Institute.
- Rinia, E. J. & van Leeuwen, Th. N. & van Vuren, H. G. & van Raan, A. F. J., 1998. "Comparative analysis of a set of bibliometric indicators and central peer review criteria: Evaluation of condensed matter physics in the Netherlands," Research Policy, Elsevier, vol. 27(1), pages 95-107, May.
- Orsenigo, L. & Pammolli, F. & Riccaboni, Massimo, 2001. "Technological change and network dynamics: Lessons from the pharmaceutical industry," Research Policy, Elsevier, vol. 30(3), pages 485-508, March.
- Bruckner, E & Ebeling, W & Jimenez Montano, M.A. & Scharnhorst, A., 1996. "Nonlinear Stochastic Effects of Substitution--An Evolutionary Approach," Journal of Evolutionary Economics, Springer, vol. 6(1), pages 1-30, February.
- Chen, Chaomei & Chen, Yue & Horowitz, Mark & Hou, Haiyan & Liu, Zeyuan & Pellegrino, Donald, 2009. "Towards an explanatory and computational theory of scientific discovery," Journal of Informetrics, Elsevier, vol. 3(3), pages 191-209.
- Nigel Gilbert, 1997. "A Simulation of the Structure of Academic Science," Sociological Research Online, Sociological Research Online, vol. 2(2), pages 3.
- David W. Galenson & Bruce A. Weinberg, 2001. "Creating Modern Art: The Changing Careers of Painters in France from Impressionism to Cubism," American Economic Review, American Economic Association, vol. 91(4), pages 1063-1071, September.
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