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Quantifying the social value of a universal COVID-19 vaccine and incentivizing its development

Author

Listed:
  • Rachel Glennerster

    (University of Chicago)

  • Thomas Kelly

    (1Day Sooner)

  • Claire T. McMahon

    (University of Chicago)

  • Christopher M. Snyder

    (Dartmouth College)

Abstract

Booster shots for COVID-19 vaccines in the United States have undergone periodic updates to target circulating variants. However, the lengthy process of development, testing, and production has resulted lags between a variant’s initial detection and the corresponding booster's rollout, by which time the booster may no longer match the circulating variant. An innovation with realistic scientific potential—a universal COVID-19 vaccine, effective against existing and future variants—could provide much more value by preempting new variants. Averaged across Monte Carlo simulations, we estimate that, even under conservative assumptions on the arrival rate of variants, a universal COVID-19 vaccine would increase health benefits over variant-specific boosters by more than $900 billion. This social value eclipses the cost of an advance market commitment to incentivize the universal vaccine by several orders of magnitude.

Suggested Citation

  • Rachel Glennerster & Thomas Kelly & Claire T. McMahon & Christopher M. Snyder, 2024. "Quantifying the social value of a universal COVID-19 vaccine and incentivizing its development," Review of Economic Design, Springer;Society for Economic Design, vol. 28(4), pages 723-761, December.
  • Handle: RePEc:spr:reecde:v:28:y:2024:i:4:d:10.1007_s10058-024-00363-z
    DOI: 10.1007/s10058-024-00363-z
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    References listed on IDEAS

    as
    1. Michael Kremer & Jonathan Levin & Christopher M. Snyder, 2020. "Advance Market Commitments: Insights from Theory and Experience," AEA Papers and Proceedings, American Economic Association, vol. 110, pages 269-273, May.
    2. Guido Alfani, 2022. "Epidemics, Inequality, and Poverty in Preindustrial and Early Industrial Times," Journal of Economic Literature, American Economic Association, vol. 60(1), pages 3-40, March.
    3. Rachel Glennerster & Christopher M. Snyder & Brandon Joel Tan, 2023. "Calculating the Costs and Benefits of Advance Preparations for Future Pandemics," IMF Economic Review, Palgrave Macmillan;International Monetary Fund, vol. 71(3), pages 611-648, September.
    4. Alvin E. Roth, 2007. "Repugnance as a Constraint on Markets," Journal of Economic Perspectives, American Economic Association, vol. 21(3), pages 37-58, Summer.
    5. Snyder, Christopher M. & Hoyt, Kendall & Gouglas, Dimitrios, 2023. "An optimal mechanism to fund the development of vaccines against emerging epidemics," Journal of Health Economics, Elsevier, vol. 91(C).
    6. Michael Kremer & Jonathan Levin & Christopher M. Snyder, 2022. "Designing Advance Market Commitments for New Vaccines," Management Science, INFORMS, vol. 68(7), pages 4786-4814, July.
    7. Warwick McKibbin & Roshen Fernando, 2020. "Global Macroeconomic Scenarios of the COVID-19 Pandemic," CAMA Working Papers 2020-62, Centre for Applied Macroeconomic Analysis, Crawford School of Public Policy, The Australian National University.
    8. Ernst R. Berndt & Rachel Glennerster & Michael R. Kremer & Jean Lee & Ruth Levine & Georg Weizsäcker & Heidi Williams, 2007. "Advance market commitments for vaccines against neglected diseases: estimating costs and effectiveness," Health Economics, John Wiley & Sons, Ltd., vol. 16(5), pages 491-511, May.
    9. Michael Kremer & Christopher M. Snyder, 2015. "Preventives Versus Treatments," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 130(3), pages 1167-1239.
    10. Susan Athey & Juan Camilo Castillo & Esha Chaudhuri & Michael Kremer & Alexandre Simoes Gomes & Christopher M Snyder, 2022. "Expanding capacity for vaccines against Covid-19 and future pandemics: a review of economic issues," Oxford Review of Economic Policy, Oxford University Press and Oxford Review of Economic Policy Limited, vol. 38(4), pages 742-770.
    11. William Msemburi & Ariel Karlinsky & Victoria Knutson & Serge Aleshin-Guendel & Somnath Chatterji & Jon Wakefield, 2023. "The WHO estimates of excess mortality associated with the COVID-19 pandemic," Nature, Nature, vol. 613(7942), pages 130-137, January.
    12. Michael Kremer & Heidi Williams, 2010. "Incentivizing Innovation: Adding to the Tool Kit," NBER Chapters, in: Innovation Policy and the Economy, Volume 10, pages 1-17, National Bureau of Economic Research, Inc.
    13. Marcus R. Keogh‐Brown & Simon Wren‐Lewis & W. John Edmunds & Philippe Beutels & Richard D. Smith, 2010. "The possible macroeconomic impact on the UK of an influenza pandemic," Health Economics, John Wiley & Sons, Ltd., vol. 19(11), pages 1345-1360, November.
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    More about this item

    Keywords

    Vaccine; COVID-19; Coronavirus; Universal vaccine; Advance market commitment;
    All these keywords.

    JEL classification:

    • H51 - Public Economics - - National Government Expenditures and Related Policies - - - Government Expenditures and Health
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • L65 - Industrial Organization - - Industry Studies: Manufacturing - - - Chemicals; Rubber; Drugs; Biotechnology; Plastics

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