Flexible scan statistic test to detect disease clusters in hierarchical trees
This paper presents a flexible scan test statistic to detect disease clusters in data sets represented as a hierarchical tree. The algorithm searches through the branches of the tree and it is able to aggregate leaves located in different branches. The test statistic combines two terms, the log-likelihood of the data and the amount of information necessary to computationally code each potential cluster. This second term penalizes the search algorithm avoiding the detection of oddly shaped clusters and it is based on the Minimum Description Length (MDL) principle. Our MDL method reaches an automatic compromise between bias and variance. We present simulated results showing that its power performance as compared to the usual scan statistic and the high accuracy of the MDL to identify clusters that are scattered on the tree. The MDL method is illustrated with a large database looking at the relationship between occupation and death from silicosis. Copyright Springer-Verlag 2012
Volume (Year): 27 (2012)
Issue (Month): 4 (December)
|Contact details of provider:|| Web page: http://www.springer.com|
|Order Information:||Web: http://www.springer.com/statistics/journal/180/PS2|
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Davis, Richard A. & Lee, Thomas C.M. & Rodriguez-Yam, Gabriel A., 2006. "Structural Break Estimation for Nonstationary Time Series Models," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 223-239, March.
When requesting a correction, please mention this item's handle: RePEc:spr:compst:v:27:y:2012:i:4:p:715-737. See general information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Sonal Shukla)or (Rebekah McClure)
If references are entirely missing, you can add them using this form.