IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0275554.html

Exploring Health-Related Quality of Life (HRQOL) among patients with HIV-associated TB in Khayelitsha, South Africa

Author

Listed:
  • John-Henry Hickman
  • Alison Swartz
  • Namhla Sicwebu
  • Cari Stek
  • Nobom Masimini
  • Christiana Nöstlinger

Abstract

Background: Health-related quality of life (HRQOL) is an important and frequently used patient-reported outcome in health research. However, little qualitative research exists in this field in South Africa. This study was set in Khayelitsha, one of the largest informal settlements in South Africa, where the burden of HIV and tuberculosis (TB) co-infection are amongst the highest in the world and significantly affect HRQOL. Objective: To explore the experience of HRQOL among patients living with HIV-associated TB. Methods: We conducted sixteen interviews with male (n = 10) and female (n = 6) adult participants (ages 24–56; median age 35) to explore their HRQOL living with HIV-associated TB, related treatment and how this impacted on life domains they considered relevant for HRQOL. We used thematic analysis to analyse data, using both an inductive and deductive analysis using an interpretive phenomenological approach (IPA). Results: Experiences of HRQOL were identified along the predominantly emerging themes of physical, social, and mental aspects of HRQOL. Identified sub-themes included well-being, loss of strength, and self-care for the physical domain; usual activities and stigma for the social domain; concerns and coping for the mental domain. The findings illustrate that HRQOL domains are interconnected through social experience. The social experience of HRQOL was identified as the common denominator connecting all domains, around which HRQOL revolved for these participants. Conclusion: HRQOL is experienced socially. The interpersonal connections patients have with significant others present as key to high HRQOL among patients living with HIV-associated TB. This study adds to the existing literature of HRQOL and examines HRQOL using IPA which may help to inform future interventions to improve HRQOL among HIV/TB patients.

Suggested Citation

  • John-Henry Hickman & Alison Swartz & Namhla Sicwebu & Cari Stek & Nobom Masimini & Christiana Nöstlinger, 2024. "Exploring Health-Related Quality of Life (HRQOL) among patients with HIV-associated TB in Khayelitsha, South Africa," PLOS ONE, Public Library of Science, vol. 19(11), pages 1-17, November.
    • Handle: RePEc:plo:pone00:0275554
    DOI: 10.1371/journal.pone.0275554
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0275554
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0275554&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0275554?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Prishah Narsai & Champaklal C. Jinabhai & Myra Taylor & Fred Stevens, 2016. "The Health Related Quality of Life of HIV Positive Respondents on Antiretroviral Treatment and HIV Negative Living in Lower Socio-Economic Housing in KwaZulu-Natal, South Africa," Social Indicators Research: An International and Interdisciplinary Journal for Quality-of-Life Measurement, Springer, vol. 127(2), pages 851-863, June.
    2. Mirna Macur, 2013. "Quality in health care: possibilities and limitations of quantitative research instruments among health care users," Quality & Quantity: International Journal of Methodology, Springer, vol. 47(3), pages 1703-1716, April.
    3. Milad Karimi & John Brazier, 2016. "Health, Health-Related Quality of Life, and Quality of Life: What is the Difference?," PharmacoEconomics, Springer, vol. 34(7), pages 645-649, July.
    4. Brazier, John & Roberts, Jennifer & Deverill, Mark, 2002. "The estimation of a preference-based measure of health from the SF-36," Journal of Health Economics, Elsevier, vol. 21(2), pages 271-292, March.
    5. Jeffrey V. Lazarus & Kelly Safreed-Harmon & Adeeba Kamarulzaman & Jane Anderson & Ricardo Baptista Leite & Georg Behrens & Linda-Gail Bekker & Sanjay Bhagani & Darren Brown & Graham Brown & Susan Buch, 2021. "Consensus statement on the role of health systems in advancing the long-term well-being of people living with HIV," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
    6. Cremers, Anne Lia & Gerrets, René & Colvin, Christopher James & Maqogi, Monwabisi & Grobusch, Martin Peter, 2018. "Tuberculosis patients and resilience: A visual ethnographic health study in Khayelitsha, Cape Town," Social Science & Medicine, Elsevier, vol. 209(C), pages 145-151.
    7. Ebrahim, Shah, 1995. "Clinical and public health perspectives and applications of health-related quality of life measurement," Social Science & Medicine, Elsevier, vol. 41(10), pages 1383-1394, November.
    8. Ingrid Eshun-Wilson & Anke Rohwer & Lynn Hendricks & Sandy Oliver & Paul Garner, 2019. "Being HIV positive and staying on antiretroviral therapy in Africa: A qualitative systematic review and theoretical model," PLOS ONE, Public Library of Science, vol. 14(1), pages 1-30, January.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Pickles, Kristen & Lancsar, Emily & Seymour, Janelle & Parkin, David & Donaldson, Cam & Carter, Stacy M., 2019. "Accounts from developers of generic health state utility instruments explain why they produce different QALYs: A qualitative study," Social Science & Medicine, Elsevier, vol. 240(C).
    2. Milad Karimi & John Brazier, 2016. "Health, Health-Related Quality of Life, and Quality of Life: What is the Difference?," PharmacoEconomics, Springer, vol. 34(7), pages 645-649, July.
    3. Natalia Hernández-Segura & Alba Marcos-Delgado & Arrate Pinto-Carral & Tania Fernández-Villa & Antonio J. Molina, 2022. "Health-Related Quality of Life (HRQOL) Instruments and Mobility: A Systematic Review," IJERPH, MDPI, vol. 19(24), pages 1-23, December.
    4. Samer A. Kharroubi & Yara Beyh & Marwa Diab El Harake & Dalia Dawoud & Donna Rowen & John Brazier, 2020. "Examining the Feasibility and Acceptability of Valuing the Arabic Version of SF-6D in a Lebanese Population," IJERPH, MDPI, vol. 17(3), pages 1-15, February.
    5. Nick Bansback & Huiying Sun & Daphne P. Guh & Xin Li & Bohdan Nosyk & Susan Griffin & Paul G. Barnett & Aslam H. Anis, 2008. "Impact of the recall period on measuring health utilities for acute events," Health Economics, John Wiley & Sons, Ltd., vol. 17(12), pages 1413-1419.
    6. Clarke, Philip & Erreygers, Guido, 2020. "Defining and measuring health poverty," Social Science & Medicine, Elsevier, vol. 244(C).
    7. Ratcliffe, Julie & Huynh, Elisabeth & Chen, Gang & Stevens, Katherine & Swait, Joffre & Brazier, John & Sawyer, Michael & Roberts, Rachel & Flynn, Terry, 2016. "Valuing the Child Health Utility 9D: Using profile case best worst scaling methods to develop a new adolescent specific scoring algorithm," Social Science & Medicine, Elsevier, vol. 157(C), pages 48-59.
    8. Anirban Basu & William Dale & Arthur Elstein & David Meltzer, 2009. "A linear index for predicting joint health‐states utilities from single health‐states utilities," Health Economics, John Wiley & Sons, Ltd., vol. 18(4), pages 403-419, April.
    9. McCabe, Christopher & Brazier, John & Gilks, Peter & Tsuchiya, Aki & Roberts, Jennifer & O'Hagan, Anthony & Stevens, Katherine, 2006. "Using rank data to estimate health state utility models," Journal of Health Economics, Elsevier, vol. 25(3), pages 418-431, May.
    10. Octavio Pano & Carmen Sayón-Orea & Alfredo Gea & Maira Bes-Rastrollo & Miguel Ángel Martínez-González & J. Alfredo Martínez, 2020. "Nutritional Determinants of Quality of Life in a Mediterranean Cohort: The SUN Study," IJERPH, MDPI, vol. 17(11), pages 1-17, May.
    11. Thomas Reinhold & Claudia Witt & Susanne Jena & Benno Brinkhaus & Stefan Willich, 2008. "Quality of life and cost-effectiveness of acupuncture treatment in patients with osteoarthritis pain," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 9(3), pages 209-219, August.
    12. Kontodimopoulos, Nick & Niakas, Dimitris, 2008. "An estimate of lifelong costs and QALYs in renal replacement therapy based on patients' life expectancy," Health Policy, Elsevier, vol. 86(1), pages 85-96, April.
    13. Allanson, Paul, 2017. "Monitoring income-related health differences between regions in Great Britain: A new measure for ordinal health data," Social Science & Medicine, Elsevier, vol. 175(C), pages 72-80.
    14. Andrew M. Jones & Audrey Laporte & Nigel Rice & Eugenio Zucchelli, 2019. "Dynamic panel data estimation of an integrated Grossman and Becker–Murphy model of health and addiction," Empirical Economics, Springer, vol. 56(2), pages 703-733, February.
    15. Makai, Peter & Brouwer, Werner B.F. & Koopmanschap, Marc A. & Stolk, Elly A. & Nieboer, Anna P., 2014. "Quality of life instruments for economic evaluations in health and social care for older people: A systematic review," Social Science & Medicine, Elsevier, vol. 102(C), pages 83-93.
    16. Stevens, K, 2010. "Valuation of the Child Health Utility Index 9D (CHU9D)," MPRA Paper 29938, University Library of Munich, Germany.
    17. Suparb Aree‐Ue & Usa Kongsombun & Inthira Roopsawang & Phichpraorn Youngcharoen, 2019. "Path model of factors influencing health‐related quality of life among older people with knee osteoarthritis," Nursing & Health Sciences, John Wiley & Sons, vol. 21(3), pages 345-351, September.
    18. Brazier, JE & Yang, Y & Tsuchiya, A, 2008. "A review of studies mapping (or cross walking) from non-preference based measures of health to generic preference-based measures," MPRA Paper 29808, University Library of Munich, Germany.
    19. Johanna L. Bosch & Elkan F. Halpern & G. Scott Gazelle, 2002. "Comparison of Preference-Based Utilities of the Short-Form 36 Health Survey and Health Utilities Index before and after Treatment of Patients with Intermittent Claudication," Medical Decision Making, , vol. 22(5), pages 403-409, October.
    20. Christopher McCabe & Katherine Stevens & Jennifer Roberts & John Brazier, 2005. "Health state values for the HUI 2 descriptive system: results from a UK survey," Health Economics, John Wiley & Sons, Ltd., vol. 14(3), pages 231-244, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0275554. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.