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Acute particulate matter exposure diminishes executive cognitive functioning after four hours regardless of inhalation pathway

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Listed:
  • Thomas Faherty

    (Earth and Environmental Sciences)

  • Jane E. Raymond

    (School of Psychology)

  • Gordon McFiggans

    (Department of Earth and Environmental Sciences)

  • Francis D. Pope

    (Earth and Environmental Sciences)

Abstract

Recent evidence suggests short-term exposure to particulate matter (PM) air pollution can impact brain function after a delay period. It is unknown whether effects are predominantly due to the olfactory or lung-brain pathways. In this study 26 adults (Mage = 27.7, SDage = 10.6) participated in four conditions. They were exposed to either high PM concentrations or clean air for one hour, using normal inhalation or restricted nasal inhalation and olfaction with a nose clip. Participants completed four cognitive tests before and four hours after exposure, assessing working memory, selective attention, emotion expression discrimination, and psychomotor vigilance. Results showed significant reductions in selective attention and emotion expression discrimination after enhanced PM versus clean air exposure. Air quality did not significantly impact psychomotor vigilance or working memory performance. Inhalation method did not significantly mediate effects, suggesting that short-term PM pollution affects cognitive function through lung-brain mechanisms, either directly or indirectly.

Suggested Citation

  • Thomas Faherty & Jane E. Raymond & Gordon McFiggans & Francis D. Pope, 2025. "Acute particulate matter exposure diminishes executive cognitive functioning after four hours regardless of inhalation pathway," Nature Communications, Nature, vol. 16(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-56508-3
    DOI: 10.1038/s41467-025-56508-3
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    References listed on IDEAS

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    1. Harvey, Lewis O., 1992. "The critical operating characteristic and the evaluation of expert judgment," Organizational Behavior and Human Decision Processes, Elsevier, vol. 53(2), pages 229-251, November.
    2. Jennifer A. Ailshire & Philippa Clarke, 2015. "Fine Particulate Matter Air Pollution and Cognitive Function Among U.S. Older Adults," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 70(2), pages 322-328.
    3. Tyler A. Jacobson & Jasdeep S. Kler & Michael T. Hernke & Rudolf K. Braun & Keith C. Meyer & William E. Funk, 2019. "Direct human health risks of increased atmospheric carbon dioxide," Nature Sustainability, Nature, vol. 2(8), pages 691-701, August.
    4. Matthew Botvinick & Leigh E. Nystrom & Kate Fissell & Cameron S. Carter & Jonathan D. Cohen, 1999. "Conflict monitoring versus selection-for-action in anterior cingulate cortex," Nature, Nature, vol. 402(6758), pages 179-181, November.
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