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Prioritizing Hepatitis C Treatment in U.S. Prisons

Author

Listed:
  • Turgay Ayer

    (H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, Georgia 30318)

  • Can Zhang

    (Fuqua School of Business, Duke University, Durham, North Carolina 27708)

  • Anthony Bonifonte

    (Data Analytics Program, Denison University, Granville, Ohio 43023)

  • Anne C. Spaulding

    (Rollins School of Public Health, Emory University, Atlanta, Georgia 30322)

  • Jagpreet Chhatwal

    (Massachusetts General Hospital Institute for Technology Assessment, Harvard Medical School, Boston, Massachusetts 02114)

Abstract

Hepatitis C virus (HCV) prevalence in prison systems is about 10 times higher than in the community. As such, prison systems offer a unique opportunity to control the HCV epidemic. New HCV-treatment drugs are very effective, but providing treatment to all inmates is prohibitively expensive unless prices fall. Current practice is to prioritize treatment based on disease severity and puts less emphasis on other factors such as the remaining sentence length and injection drug use behavior. In “Prioritizing Hepatitis C Treatment in U.S. Prisons,” T. Ayer, C. Zhang, A. Bonifonte, A. Spaulding, and J. Chhatwal analyze optimal approaches for treatment prioritization under resource constraints by developing a restless bandit modeling framework. They present an easy-to-implement closed-form index policy to support hepatitis C treatment prioritization decisions in U.S. prisons. They also test their proposed policy using a detailed, realistic agent-based simulation model and shed light on several controversial health policy decisions related to hepatitis C treatment prioritization.

Suggested Citation

  • Turgay Ayer & Can Zhang & Anthony Bonifonte & Anne C. Spaulding & Jagpreet Chhatwal, 2019. "Prioritizing Hepatitis C Treatment in U.S. Prisons," Operations Research, INFORMS, vol. 67(3), pages 853-873, May.
  • Handle: RePEc:inm:oropre:v:67:y:2019:i:3:p:853-873
    DOI: 10.1287/opre.2018.1812
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    Cited by:

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    3. Emanuele Borgonovo & Marco Pangallo & Jan Rivkin & Leonardo Rizzo & Nicolaj Siggelkow, 2022. "Sensitivity analysis of agent-based models: a new protocol," Computational and Mathematical Organization Theory, Springer, vol. 28(1), pages 52-94, March.
    4. Urtzi Ayesta & Manu K. Gupta & Ina Maria Verloop, 2021. "On the computation of Whittle’s index for Markovian restless bandits," Mathematical Methods of Operations Research, Springer;Gesellschaft für Operations Research (GOR);Nederlands Genootschap voor Besliskunde (NGB), vol. 93(1), pages 179-208, February.
    5. José Niño-Mora, 2022. "Multi-Gear Bandits, Partial Conservation Laws, and Indexability," Mathematics, MDPI, vol. 10(14), pages 1-31, July.
    6. Ya‐Tang Chuang & Manaf Zargoush & Somayeh Ghazalbash & Saied Samiedaluie & Kerry Kuluski & Sara Guilcher, 2023. "From prediction to decision: Optimizing long‐term care placements among older delayed discharge patients," Production and Operations Management, Production and Operations Management Society, vol. 32(4), pages 1041-1058, April.
    7. José Niño-Mora, 2020. "Fast Two-Stage Computation of an Index Policy for Multi-Armed Bandits with Setup Delays," Mathematics, MDPI, vol. 9(1), pages 1-36, December.
    8. Elisa F. Long & Gilberto Montibeller & Jun Zhuang, 2022. "Health Decision Analysis: Evolution, Trends, and Emerging Topics," Decision Analysis, INFORMS, vol. 19(4), pages 255-264, December.

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