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Increased Mortality Associated with Well-Water Arsenic Exposure in Inner Mongolia, China

Author

Listed:
  • Timothy J. Wade

    (US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Chapel Hill, North Carolina, USA)

  • Yajuan Xia

    (Inner Mongolia Center for Endemic Disease Control and Research, Huhhot, Inner Mongolia, China)

  • Kegong Wu

    (Inner Mongolia Center for Endemic Disease Control and Research, Huhhot, Inner Mongolia, China)

  • Yanhong Li

    (Inner Mongolia Center for Endemic Disease Control and Research, Huhhot, Inner Mongolia, China)

  • Zhixiong Ning

    (Ba Men Anti Epidemic Station, Bayingnormen, Inner Mongolia, China)

  • X Chris Le

    (University of Alberta, Department of Public Health Sciences, Edmonton, Canada)

  • Xiufen Lu

    (University of Alberta, Department of Public Health Sciences, Edmonton, Canada)

  • Yong Feng

    (Hangjin Hou Centers for Disease Control, Hangjin Hou, Inner Mongolia, China)

  • Xingzhou He

    (Chinese Academy of Preventative Medicine, Institute of Environmental Health &Engineering, Beijing, China)

  • Judy L. Mumford

    (US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Chapel Hill, North Carolina, USA)

Abstract

We conducted a retrospective mortality study in an Inner Mongolian village exposed to well water contaminated by arsenic since the 1980s. Deaths occurring between January 1, 1997 and December 1, 2004 were classified according to underlying cause and water samples from household wells were tested for total arsenic. Heart disease mortality was associated with arsenic exposure, and the association strengthened with time exposed to the water source. Cancer mortality and all-cause mortality were associated with well-water arsenic exposure among those exposed 10-20 years. This is the first study to document increased arsenic-associated mortality in the Bayingnormen region of Inner Mongolia.

Suggested Citation

  • Timothy J. Wade & Yajuan Xia & Kegong Wu & Yanhong Li & Zhixiong Ning & X Chris Le & Xiufen Lu & Yong Feng & Xingzhou He & Judy L. Mumford, 2009. "Increased Mortality Associated with Well-Water Arsenic Exposure in Inner Mongolia, China," IJERPH, MDPI, vol. 6(3), pages 1-17, March.
    • Handle: RePEc:gam:jijerp:v:6:y:2009:i:3:p:1107-1123:d:4275
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    References listed on IDEAS

    as
    1. Xiaojuan Guo & Yoshihisa Fujino & Xiaolei Ye & Jun Liu & Takesumi Yoshimura, 2006. "Association between Multi-level Inorganic Arsenic Exposure from Drinking Water and Skin Lesions in China," IJERPH, MDPI, vol. 3(3), pages 1-6, September.
    2. Rick L. Williams, 2000. "A Note on Robust Variance Estimation for Cluster-Correlated Data," Biometrics, The International Biometric Society, vol. 56(2), pages 645-646, June.
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    Cited by:

    1. Claudia Avila-Sandoval & Hugo Júnez-Ferreira & Julián González-Trinidad & Carlos Bautista-Capetillo & Anuard Pacheco-Guerrero & Edith Olmos-Trujillo, 2018. "Spatio-Temporal Analysis of Natural and Anthropogenic Arsenic Sources in Groundwater Flow Systems," IJERPH, MDPI, vol. 15(11), pages 1-18, October.
    2. Jinyao Mo & Yajuan Xia & Timothy J. Wade & David M. DeMarini & Mercy Davidson & Judy Mumford, 2011. "Altered Gene Expression by Low-Dose Arsenic Exposure in Humans and Cultured Cardiomyocytes: Assessment by Real-Time PCR Arrays," IJERPH, MDPI, vol. 8(6), pages 1-19, June.

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