IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v55y2011i3p1426-1444.html
   My bibliography  Save this article

Practical estimation of high dimensional stochastic differential mixed-effects models

Author

Listed:
  • Picchini, Umberto
  • Ditlevsen, Susanne

Abstract

Stochastic differential equations (SDEs) are established tools for modeling physical phenomena whose dynamics are affected by random noise. By estimating parameters of an SDE, intrinsic randomness of a system around its drift can be identified and separated from the drift itself. When it is of interest to model dynamics within a given population, i.e. to model simultaneously the performance of several experiments or subjects, mixed-effects modelling allows for the distinction of between and within experiment variability. A framework for modeling dynamics within a population using SDEs is proposed, representing simultaneously several sources of variation: variability between experiments using a mixed-effects approach and stochasticity in the individual dynamics, using SDEs. These stochastic differential mixed-effects models have applications in e.g. pharmacokinetics/pharmacodynamics and biomedical modelling. A parameter estimation method is proposed and computational guidelines for an efficient implementation are given. Finally the method is evaluated using simulations from standard models like the two-dimensional Ornstein-Uhlenbeck (OU) and the square root models.

Suggested Citation

  • Picchini, Umberto & Ditlevsen, Susanne, 2011. "Practical estimation of high dimensional stochastic differential mixed-effects models," Computational Statistics & Data Analysis, Elsevier, vol. 55(3), pages 1426-1444, March.
    • Handle: RePEc:eee:csdana:v:55:y:2011:i:3:p:1426-1444
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167-9473(10)00377-4
    Download Restriction: Full text for ScienceDirect subscribers only.
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. repec:dau:papers:123456789/1124 is not listed on IDEAS
    2. Tang, Cheng Yong & Chen, Song Xi, 2009. "Parameter estimation and bias correction for diffusion processes," Journal of Econometrics, Elsevier, vol. 149(1), pages 65-81, April.
    3. A. S. Hurn & J. I. Jeisman & K. A. Lindsay, 0. "Seeing the Wood for the Trees: A Critical Evaluation of Methods to Estimate the Parameters of Stochastic Differential Equations," Journal of Financial Econometrics, Oxford University Press, vol. 5(3), pages 390-455.
    4. John C. Cox & Jonathan E. Ingersoll Jr. & Stephen A. Ross, 2005. "A Theory Of The Term Structure Of Interest Rates," World Scientific Book Chapters, in: Sudipto Bhattacharya & George M Constantinides (ed.), Theory Of Valuation, chapter 5, pages 129-164, World Scientific Publishing Co. Pte. Ltd..
    5. Benjamin Favetto & Adeline Samson, 2010. "Parameter Estimation for a Bidimensional Partially Observed Ornstein–Uhlenbeck Process with Biological Application," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 37(2), pages 200-220, June.
    6. Joe, Harry, 2008. "Accuracy of Laplace approximation for discrete response mixed models," Computational Statistics & Data Analysis, Elsevier, vol. 52(12), pages 5066-5074, August.
    7. Hyejin KO & Marie Davidian, 2000. "Correcting for Measurement Error in Individual-Level Covariates in Nonlinear Mixed Effects Models," Biometrics, The International Biometric Society, vol. 56(2), pages 368-375, June.
    8. repec:dau:papers:123456789/4642 is not listed on IDEAS
    9. Sophie Donnet & Jean-Louis Foulley & Adeline Samson, 2010. "Bayesian Analysis of Growth Curves Using Mixed Models Defined by Stochastic Differential Equations," Biometrics, The International Biometric Society, vol. 66(3), pages 733-741, September.
    10. Skaug, Hans J. & Fournier, David A., 2006. "Automatic approximation of the marginal likelihood in non-Gaussian hierarchical models," Computational Statistics & Data Analysis, Elsevier, vol. 51(2), pages 699-709, November.
    11. Umberto Picchini & Andrea De Gaetano & Susanne Ditlevsen, 2010. "Stochastic Differential Mixed‐Effects Models," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 37(1), pages 67-90, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Delattre, Maud & Genon-Catalot, Valentine & Larédo, Catherine, 2018. "Parametric inference for discrete observations of diffusion processes with mixed effects," Stochastic Processes and their Applications, Elsevier, vol. 128(6), pages 1929-1957.
    2. Oscar García, 2019. "Estimating reducible stochastic differential equations by conversion to a least-squares problem," Computational Statistics, Springer, vol. 34(1), pages 23-46, March.
    3. Charlotte Dion, 2016. "Nonparametric estimation in a mixed-effect Ornstein–Uhlenbeck model," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 79(8), pages 919-951, November.
    4. Maud Delattre & Valentine Genon-Catalot & Catherine Larédo, 2018. "Approximate maximum likelihood estimation for stochastic differential equations with random effects in the drift and the diffusion," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 81(8), pages 953-983, November.
    5. B. L. S. Prakasa Rao, 2021. "Nonparametric Estimation for Stochastic Differential Equations Driven by Mixed Fractional Brownian Motion with Random Effects," Sankhya A: The Indian Journal of Statistics, Springer;Indian Statistical Institute, vol. 83(2), pages 554-568, August.
    6. Comte, F. & Genon-Catalot, V. & Samson, A., 2013. "Nonparametric estimation for stochastic differential equations with random effects," Stochastic Processes and their Applications, Elsevier, vol. 123(7), pages 2522-2551.
    7. Fabienne Comte & Nicolas Marie, 2021. "Nonparametric estimation for I.I.D. paths of fractional SDE," Statistical Inference for Stochastic Processes, Springer, vol. 24(3), pages 669-705, October.
    8. Wiqvist, Samuel & Golightly, Andrew & McLean, Ashleigh T. & Picchini, Umberto, 2021. "Efficient inference for stochastic differential equation mixed-effects models using correlated particle pseudo-marginal algorithms," Computational Statistics & Data Analysis, Elsevier, vol. 157(C).
    9. Maud Delattre & Valentine Genon-Catalot & Adeline Samson, 2013. "Maximum Likelihood Estimation for Stochastic Differential Equations with Random Effects," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 40(2), pages 322-343, June.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Oscar García, 2019. "Estimating reducible stochastic differential equations by conversion to a least-squares problem," Computational Statistics, Springer, vol. 34(1), pages 23-46, March.
    2. Emma M. Iglesias & Garry D. A. Phillips, 2020. "Further Results on Pseudo‐Maximum Likelihood Estimation and Testing in the Constant Elasticity of Variance Continuous Time Model," Journal of Time Series Analysis, Wiley Blackwell, vol. 41(2), pages 357-364, March.
    3. Christensen, T.M. & Hurn, A.S. & Lindsay, K.A., 2008. "The Devil is in the Detail: Hints for Practical Optimisation," Economic Analysis and Policy, Elsevier, vol. 38(2), pages 345-368, September.
    4. Varughese, Melvin M., 2013. "Parameter estimation for multivariate diffusion systems," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 417-428.
    5. Stan Hurn & J.Jeisman & K.A. Lindsay, 2006. "Teaching an old dog new tricks: Improved estimation of the parameters of SDEs by numerical solution of the Fokker-Planck equation," Stan Hurn Discussion Papers 2006-01, School of Economics and Finance, Queensland University of Technology.
    6. Kozarski, R., 2013. "Pricing and hedging in the VIX derivative market," Other publications TiSEM 221fefe0-241e-4914-b6bd-c, Tilburg University, School of Economics and Management.
    7. Wang, Xiaohu & Phillips, Peter C.B. & Yu, Jun, 2011. "Bias in estimating multivariate and univariate diffusions," Journal of Econometrics, Elsevier, vol. 161(2), pages 228-245, April.
    8. Noh, Jungsik & Lee, Seung Y. & Lee, Sangyeol, 2012. "Quantile regression estimation for discretely observed SDE models with compound Poisson jumps," Economics Letters, Elsevier, vol. 117(3), pages 734-738.
    9. Delattre, Maud & Genon-Catalot, Valentine & Larédo, Catherine, 2018. "Parametric inference for discrete observations of diffusion processes with mixed effects," Stochastic Processes and their Applications, Elsevier, vol. 128(6), pages 1929-1957.
    10. Son Le, 2018. "Algorithmic Trading with Fitted Q Iteration and Heston Model," Papers 1805.07478, arXiv.org.
    11. Charlotte Dion, 2016. "Nonparametric estimation in a mixed-effect Ornstein–Uhlenbeck model," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 79(8), pages 919-951, November.
    12. Aït-Sahalia, Yacine & Kimmel, Robert L., 2010. "Estimating affine multifactor term structure models using closed-form likelihood expansions," Journal of Financial Economics, Elsevier, vol. 98(1), pages 113-144, October.
    13. Tao Zou & Song Xi Chen, 2017. "Enhancing Estimation for Interest Rate Diffusion Models With Bond Prices," Journal of Business & Economic Statistics, Taylor & Francis Journals, vol. 35(3), pages 486-498, July.
    14. Xiao Huang, 2011. "Quasi‐maximum likelihood estimation of discretely observed diffusions," Econometrics Journal, Royal Economic Society, vol. 14(2), pages 241-256, July.
    15. Kleppe, Tore Selland & Skaug, Hans Julius, 2012. "Fitting general stochastic volatility models using Laplace accelerated sequential importance sampling," Computational Statistics & Data Analysis, Elsevier, vol. 56(11), pages 3105-3119.
    16. Zi‐Yi Guo, 2021. "Out‐of‐sample performance of bias‐corrected estimators for diffusion processes," Journal of Forecasting, John Wiley & Sons, Ltd., vol. 40(2), pages 243-268, March.
    17. Øystein Sørensen & Anders M. Fjell & Kristine B. Walhovd, 2023. "Longitudinal Modeling of Age-Dependent Latent Traits with Generalized Additive Latent and Mixed Models," Psychometrika, Springer;The Psychometric Society, vol. 88(2), pages 456-486, June.
    18. Huang Xiao, 2013. "Quasi-maximum likelihood estimation of multivariate diffusions," Studies in Nonlinear Dynamics & Econometrics, De Gruyter, vol. 17(2), pages 179-197, April.
    19. Wang, Yunyan & Zhang, Lixin & Tang, Mingtian, 2012. "Local M-estimation for jump-diffusion processes," Statistics & Probability Letters, Elsevier, vol. 82(7), pages 1273-1284.
    20. Filipović, Damir & Mayerhofer, Eberhard & Schneider, Paul, 2013. "Density approximations for multivariate affine jump-diffusion processes," Journal of Econometrics, Elsevier, vol. 176(2), pages 93-111.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:55:y:2011:i:3:p:1426-1444. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.