IDEAS home Printed from https://ideas.repec.org/p/egu/wpaper/1210.html
   My bibliography  Save this paper

The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008

Author

Listed:
  • Gaston Heimeriks

    ()

  • Ron Boschma

    ()

Abstract

This study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986-2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new cognitive developments within this scientific field. Our analyses show that biotech is subject to a path- and place-dependent process of knowledge production. We observed a high degree of re-occurrences of similar key topics in biotech in consecutive years. Furthermore, slow growth cities in biotech are characterized by topics that are less technologically related to other topics, while high growth cities in biotech contribute to topics that are more related to the entire set of existing topics. Slow growth and stable growth cities in biotech introduced more new topics, while fast growth cities in biotech introduced more promising topics. Slow growth cities also showed low levels of research collaboration, as compared to stable and high growth cities.

Suggested Citation

  • Gaston Heimeriks & Ron Boschma, 2012. "The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008," Papers in Evolutionary Economic Geography (PEEG) 1210, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Jun 2012.
  • Handle: RePEc:egu:wpaper:1210
    as

    Download full text from publisher

    File URL: http://econ.geo.uu.nl/peeg/peeg1210.pdf
    File Function: Version June 2012
    Download Restriction: no

    Other versions of this item:

    References listed on IDEAS

    as
    1. Frank Neffke & Martin Henning & Ron Boschma, 2011. "How Do Regions Diversify over Time? Industry Relatedness and the Development of New Growth Paths in Regions," Economic Geography, Clark University, vol. 87(3), pages 237-265, July.
    2. Philip McCann, 2007. "Globalization and economic geography: the world is curved, not flat," Cambridge Journal of Regions, Economy and Society, Cambridge Political Economy Society, vol. 1(3), pages 351-370.
    3. Ron Boschma & Ron Martin (ed.), 2010. "The Handbook of Evolutionary Economic Geography," Books, Edward Elgar Publishing, number 12864, April.
    4. Ron Boschma & Asier Minondo & Mikel Navarro, 2013. "The Emergence of New Industries at the Regional Level in S pain: A Proximity Approach Based on Product Relatedness," Economic Geography, Clark University, vol. 89(1), pages 29-51, January.
    5. Jarno Hoekman & Koen Frenken & Frank Oort, 2009. "The geography of collaborative knowledge production in Europe," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 43(3), pages 721-738, September.
    6. C. A. Hidalgo & B. Klinger & A. -L. Barabasi & R. Hausmann, 2007. "The Product Space Conditions the Development of Nations," Papers 0708.2090, arXiv.org.
    7. Lynne G. Zucker & Michael R. Darby, 2009. "Star Scientists, Innovation and Regional and National Immigration," Chapters,in: Entrepreneurship and Openness, chapter 6 Edward Elgar Publishing.
    8. Trippl, Michaela, 2009. "Islands of Innovation and Internationally Networked Labor Markets. Magnetic Centers for Star Scientists?," SRE-Discussion Papers 138, WU Vienna University of Economics and Business.
    9. Jackie Krafft & Francesco Quatraro & Pier Paolo Saviotti, 2011. "The knowledge-base evolution in biotechnology: a social network analysis," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 20(5), pages 445-475.
    10. M. S. Gertler & Y. M. Levitte, 2005. "Local Nodes in Global Networks: The Geography of Knowledge Flows in Biotechnology Innovation," Industry and Innovation, Taylor & Francis Journals, vol. 12(4), pages 487-507.
    11. Ron Boschma & Simona Iammarino, 2009. "Related Variety, Trade Linkages, and Regional Growth in Italy," Economic Geography, Clark University, vol. 85(3), pages 289-311, July.
    12. repec:oxf:wpaper:084 is not listed on IDEAS
    13. Bjørn T. Asheim, 2007. "Industrial Districts as ‘Learning Regions’: A Condition for Prosperity," Chapters,in: The Learning Region, chapter 4 Edward Elgar Publishing.
    14. Cooke, Philip, 2001. "Regional Innovation Systems, Clusters, and the Knowledge Economy," Industrial and Corporate Change, Oxford University Press, vol. 10(4), pages 945-974, December.
    15. Philip Cooke, 2006. "Global Bioregional Networks: A New Economic Geography of Bioscientific Knowledge," European Planning Studies, Taylor & Francis Journals, vol. 14(9), pages 1265-1285, April.
    16. Breschi, Stefano & Lissoni, Francesco & Malerba, Franco, 2003. "Knowledge-relatedness in firm technological diversification," Research Policy, Elsevier, vol. 32(1), pages 69-87, January.
    17. Phil Cooke, 2006. "Global Bioregions: Knowledge Domains, Capabilities and Innovation System Networks," Industry and Innovation, Taylor & Francis Journals, vol. 13(4), pages 437-458.
    18. Meric S. Gertler, 2003. "Tacit knowledge and the economic geography of context, or The undefinable tacitness of being (there)," Journal of Economic Geography, Oxford University Press, vol. 3(1), pages 75-99, January.
    19. Frenken, Koen & Hardeman, Sjoerd & Hoekman, Jarno, 2009. "Spatial scientometrics: Towards a cumulative research program," Journal of Informetrics, Elsevier, vol. 3(3), pages 222-232.
    20. Munawar Iqbal & David T. Llewellyn, 2002. "Introduction," Chapters,in: Islamic Banking and Finance, chapter 1 Edward Elgar Publishing.
    21. Steven Klepper, 2007. "Disagreements, Spinoffs, and the Evolution of Detroit as the Capital of the U.S. Automobile Industry," Management Science, INFORMS, vol. 53(4), pages 616-631, April.
    22. Lucio-Arias, Diana & Leydesdorff, Loet, 2009. "The dynamics of exchanges and references among scientific texts, and the autopoiesis of discursive knowledge," Journal of Informetrics, Elsevier, vol. 3(3), pages 261-271.
    23. Stefano Breschi & Francesco Lissoni, 2009. "Mobility of skilled workers and co-invention networks: an anatomy of localized knowledge flows," Journal of Economic Geography, Oxford University Press, vol. 9(4), pages 439-468, July.
    24. Dominique Foray, 2006. "The Economics of Knowledge," MIT Press Books, The MIT Press, edition 1, volume 1, number 0262562235, January.
    25. Lambiotte, R. & Panzarasa, P., 2009. "Communities, knowledge creation, and information diffusion," Journal of Informetrics, Elsevier, vol. 3(3), pages 180-190.
    26. Roberta Capello, 1999. "Spatial Transfer of Knowledge in High Technology Milieux: Learning Versus Collective Learning Processes," Regional Studies, Taylor & Francis Journals, vol. 33(4), pages 353-365.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Boschma, Ron & Heimeriks, Gaston & Balland, Pierre-Alexandre, 2014. "Scientific knowledge dynamics and relatedness in biotech cities," Research Policy, Elsevier, vol. 43(1), pages 107-114.
    2. Gaston Heimeriks & Pierre-Alexandre Balland, 2016. "How smart is specialisation? An analysis of specialisation patterns in knowledge production," Science and Public Policy, Oxford University Press, vol. 43(4), pages 562-574.
    3. Alkemade, Floortje & Heimeriks, Gaston & Schoen, Antoine & Villard, Lionel & Laurens, Patricia, 2015. "Tracking the internationalization of multinational corporate inventive activity: national and sectoral characteristics," Research Policy, Elsevier, vol. 44(9), pages 1763-1772.
    4. Jing Xiao & Ron Boschma & Martin Andersson, 2016. "Industrial diversification in Europe: The differentiated role of relatedness," Papers in Evolutionary Economic Geography (PEEG) 1627, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Aug 2016.
    5. Miozzo, Marcela & DiVito, Lori, 2016. "Growing fast or slow?: Understanding the variety of paths and the speed of early growth of entrepreneurial science-based firms," Research Policy, Elsevier, vol. 45(5), pages 964-986.
    6. Lisa Östbring & Rikard Eriksson & Urban Lindgren, 2015. "Relatedness through experience: On the importance of collected worker experiences for plant performance," Papers in Evolutionary Economic Geography (PEEG) 1530, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Sep 2015.
    7. Thomas Brenner & Johann Peter Murmann, 2016. "Using simulation experiments to test historical explanations: the development of the German dye industry 1857-1913," Journal of Evolutionary Economics, Springer, vol. 26(4), pages 907-932, October.
    8. Ron Boschma, 2017. "Relatedness as driver behind regional diversification: a research agenda," Papers in Evolutionary Economic Geography (PEEG) 1702, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Jan 2017.
    9. Ron Boschma, Lars Coenen, Koen Frenken, Bernhard Truffer & Lars Coenen & Koen Frenken & Bernhard Truffer, 2016. "Towards a theory of regional diversification," Papers in Evolutionary Economic Geography (PEEG) 1617, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Jul 2016.
    10. Martijn van den Berge & Anet Weterings, 2014. "Relatedness in eco-technological development in European regions," Papers in Evolutionary Economic Geography (PEEG) 1413, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Jun 2014.

    More about this item

    Keywords

    title words; branching; geography of biotechnology; scientific knowledge production; path dependence; place dependence;

    JEL classification:

    • O33 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Technological Change: Choices and Consequences; Diffusion Processes
    • R11 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General Regional Economics - - - Regional Economic Activity: Growth, Development, Environmental Issues, and Changes
    • L65 - Industrial Organization - - Industry Studies: Manufacturing - - - Chemicals; Rubber; Drugs; Biotechnology; Plastics
    • D83 - Microeconomics - - Information, Knowledge, and Uncertainty - - - Search; Learning; Information and Knowledge; Communication; Belief; Unawareness

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:egu:wpaper:1210. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (). General contact details of provider: http://edirc.repec.org/data/deguunl.html .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.