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Towards a better QALY model

  • José-Mar�a Abellán-Perpi�án

    (Department of Applied Economics, University of Murcia, Spain)

  • José-Luis Pinto-Prades
  • Ildefonso Méndez-Mart�nez

    (Department of Applied Economics, University of Murcia, Spain)

  • Xabier Bad�a-Llach

    (Health Outcomes Research Europe, Spain)

This paper presents a test of the predictive validity of various classes of QALY models (i.e. linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in nonchronic health profiles. The chronic TTO utilities were then used to predict the responses to TTO questions with nonchronic health profiles. We find that the power QALY model clearly outperforms linear and exponential QALY models. Optimal power coefficient is 0.65. Our results suggest that TTO-based QALY calculations may be biased. This bias can be corrected using a power QALY model. Copyright © 2006 John Wiley & Sons, Ltd.

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Article provided by John Wiley & Sons, Ltd. in its journal Health Economics.

Volume (Year): 15 (2006)
Issue (Month): 7 ()
Pages: 665-676

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Handle: RePEc:wly:hlthec:v:15:y:2006:i:7:p:665-676
Contact details of provider: Web page: http://www3.interscience.wiley.com/cgi-bin/jhome/5749

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