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Conceptualizing the landscape of digital health entrepreneurship: a systematic review and research agenda

Author

Listed:
  • Sascha Noel Weimar

    (Karlsruhe Institute of Technology (KIT))

  • Rahel Sophie Martjan

    (Karlsruhe Institute of Technology (KIT))

  • Orestis Terzidis

    (Karlsruhe Institute of Technology (KIT))

Abstract

Digital health, which encompasses the use of digital technology to enhance and support healthcare, can potentially transform the healthcare industry. As healthcare systems struggle to provide high-quality care, entrepreneurs and startups have turned to digital health technology to create innovative products and services that aim at improving healthcare outcomes and reducing costs. This has made digital health entrepreneurship a major driving force for achieving good health and high-quality care. The study aims to analyze the current state of research in digital health entrepreneurship by identifying contributing disciplines and common research themes. A comprehensive literature review based on state-of-the-art definitions of digital health entrepreneurship was conducted to achieve this goal. A total of 164 articles met the final inclusion criteria, and the subsequent inductive analysis revealed the presence of three contributing disciplines and ten distinct themes: Academia Transfer and Education, Ecosystem and Stakeholder, Product and Business Development, Business Model, Classification, Management and Strategy, Regulation, Digital Technology, Implementation and Adoption, and Evaluation. These themes were organized into a conceptual framework depicting the internal and external building blocks of digital health entrepreneurship. The review highlights the importance of a structured understanding of the industry, including its business models and regulatory environment, as well as the role of the various healthcare stakeholders. This analysis can guide researchers and entrepreneurs seeking to navigate the digital health landscape and proposes further research avenues.

Suggested Citation

  • Sascha Noel Weimar & Rahel Sophie Martjan & Orestis Terzidis, 2025. "Conceptualizing the landscape of digital health entrepreneurship: a systematic review and research agenda," Management Review Quarterly, Springer, vol. 75(2), pages 1619-1667, June.
  • Handle: RePEc:spr:manrev:v:75:y:2025:i:2:d:10.1007_s11301-024-00417-0
    DOI: 10.1007/s11301-024-00417-0
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    1. Caroline Omoanatse Alenoghena & Adeiza James Onumanyi & Henry Ohiani Ohize & Achonu Oluwole Adejo & Maxwell Oligbi & Shaibu Ibrahim Ali & Supreme Ayewoh Okoh, 2022. "eHealth: A Survey of Architectures, Developments in mHealth, Security Concerns and Solutions," IJERPH, MDPI, vol. 19(20), pages 1-54, October.
    2. Lehoux, P. & Daudelin, G. & Williams-Jones, B. & Denis, J.-L. & Longo, C., 2014. "How do business model and health technology design influence each other? Insights from a longitudinal case study of three academic spin-offs," Research Policy, Elsevier, vol. 43(6), pages 1025-1038.
    3. Urueña, Alberto & Hidalgo, Antonio & Arenas, Álvaro E., 2016. "Identifying capabilities in innovation projects: Evidences from eHealth," Journal of Business Research, Elsevier, vol. 69(11), pages 4843-4848.
    4. Elin Merethe Oftedal & Lene Foss & Tatiana Iakovleva, 2019. "Responsible for Responsibility? A Study of Digital E-health Startups," Sustainability, MDPI, vol. 11(19), pages 1-21, September.
    5. Lopez, David & Brown, Alan W. & Plans, David, 2019. "Developing opportunities in digital health: The case of BioBeats Ltd," Journal of Business Venturing Insights, Elsevier, vol. 11(C), pages 1-1.
    6. Oderanti, Festus Oluseyi & Li, Feng & Cubric, Marija & Shi, Xiaohui, 2021. "Business models for sustainable commercialisation of digital healthcare (eHealth) innovations for an increasingly ageing population," Technological Forecasting and Social Change, Elsevier, vol. 171(C).
    7. Florence Degavre & Suzanne Kieffer & David Bol & Rémi Dekimpe & Charlotte Desterbecq & Thibault Pirson & Georgiana Sandu & Sandy Tubeuf, 2022. "Searching for Sustainability in Health Systems: Toward a Multidisciplinary Evaluation of Mobile Health Innovations," Sustainability, MDPI, vol. 14(9), pages 1-17, April.
    8. Kraus, Sascha & Schiavone, Francesco & Pluzhnikova, Anna & Invernizzi, Anna Chiara, 2021. "Digital transformation in healthcare: Analyzing the current state-of-research," Journal of Business Research, Elsevier, vol. 123(C), pages 557-567.
    9. Chakraborty, Imon & Ilavarasan, P. Vigneswara & Edirippulige, Sisira, 2021. "Health-tech startups in healthcare service delivery: A scoping review," Social Science & Medicine, Elsevier, vol. 278(C).
    10. Liezl Van Dyk, 2014. "A Review of Telehealth Service Implementation Frameworks," IJERPH, MDPI, vol. 11(2), pages 1-20, January.
    11. Lien Denoo & Helena Yli-Renko, 2019. "Entrepreneurship in a New Digital Industry: The Emergence and Growth of Mobile Health," FGF Studies in Small Business and Entrepreneurship, in: Ronny Baierl & Judith Behrens & Alexander Brem (ed.), Digital Entrepreneurship, pages 79-98, Springer.
    12. Katarzyna Kolasa & Grzegorz Kozinski, 2020. "How to Value Digital Health Interventions? A Systematic Literature Review," IJERPH, MDPI, vol. 17(6), pages 1-22, March.
    13. Matti Muhos & Martti Saarela & Delbert Foit & Lada Rasochova, 2019. "Management priorities of digital health service start-ups in California," International Entrepreneurship and Management Journal, Springer, vol. 15(1), pages 43-62, March.
    14. Sascha Kraus & Matthias Breier & Sonia Dasí-Rodríguez, 2020. "The art of crafting a systematic literature review in entrepreneurship research," International Entrepreneurship and Management Journal, Springer, vol. 16(3), pages 1023-1042, September.
    15. Karla Margarete Gehde & Florian Rausch & Jens Leker, 2022. "Business Model Configurations In Digital Healthcare—A German Case Study About Digital Transformation," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 26(03), pages 1-78, April.
    16. Hannah S Chen†& Juliet T Jarrell & Kristy A Carpenter & David S Cohen & Xudong Huang, 2019. "Blockchain in Healthcare: A Patient-Centered Model," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 20(3), pages 15017-15022, August.
    17. Sebastian Hermes & Tobias Riasanow & Eric K. Clemons & Markus Böhm & Helmut Krcmar, 2020. "The digital transformation of the healthcare industry: exploring the rise of emerging platform ecosystems and their influence on the role of patients," Business Research, Springer;German Academic Association for Business Research, vol. 13(3), pages 1033-1069, November.
    18. Janette Hughes & Marilyn Lennon & Robert J. Rogerson & George Crooks, 2021. "Scaling Digital Health Innovation: Developing a New ‘Service Readiness Level’ Framework of Evidence," IJERPH, MDPI, vol. 18(23), pages 1-19, November.
    19. Julie Bastianutti & Caroline Gauthier & Meyer Haggege, 2018. "Managerial capabilities to address digital business models: The case of digital health," Post-Print hal-01795210, HAL.
    20. Munjae Lee & Sewon Park & Kyu-Sung Lee, 2019. "What Are the Features of Successful Medical Device Start-Ups? Evidence from KOREA," Sustainability, MDPI, vol. 11(7), pages 1-17, April.
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    More about this item

    Keywords

    Digital health; Telehealth; eHealth; Startup; Entrepreneurship; Innovation;
    All these keywords.

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General
    • K23 - Law and Economics - - Regulation and Business Law - - - Regulated Industries and Administrative Law
    • M13 - Business Administration and Business Economics; Marketing; Accounting; Personnel Economics - - Business Administration - - - New Firms; Startups

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