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Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis

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  • Semagn Mekonnen Abate
  • Siraj Ahmed Ali
  • Bahiru Mantfardo
  • Bivash Basu

Abstract

Background: The rate of ICU admission among patients with coronavirus varied from 3% to 100% and the mortality was as high as 86% of admitted patients. The objective of the systematic review was to investigate the rate of ICU admission, mortality, morbidity, and complications among patients with coronavirus. Methods: A comprehensive strategy was conducted in PubMed/Medline; Science direct and LILACS from December 2002 to May 2020 without language restriction. The Heterogeneity among the included studies was checked with forest plot, χ2 test, I2 test, and the p-values. All observational studies reporting rate of ICU admission, the prevalence of mortality and its determinants among ICU admitted patients with coronavirus were included and the rest were excluded Result: A total of 646 articles were identified from different databases and 50 articles were selected for evaluation. Thirty-seven Articles with 24983 participants were included. The rate of ICU admission was 32% (95% CI: 26 to 38, 37 studies and 32, 741 participants). The Meta-Analysis revealed that the pooled prevalence of mortality in patients with coronavirus disease in ICU was 39% (95% CI: 34 to 43, 37 studies and 24, 983 participants). Conclusion: The Meta-Analysis revealed that approximately one-third of patients admitted to ICU with severe Coronavirus disease and more than thirty percent of patients admitted to ICU with a severe form of COVID-19 for better care died which warns the health care stakeholders to give attention to intensive care patients. Registration: This Systematic review and Meta-Analysis was registered in Prospero international prospective register of systemic reviews (CRD42020177095) on April 9/2020.

Suggested Citation

  • Semagn Mekonnen Abate & Siraj Ahmed Ali & Bahiru Mantfardo & Bivash Basu, 2020. "Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-19, July.
  • Handle: RePEc:plo:pone00:0235653
    DOI: 10.1371/journal.pone.0235653
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    References listed on IDEAS

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    1. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
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    As found on the RePEc Biblio, the curated bibliography for Economics:
    1. > Economics of Welfare > Health Economics > Economics of Pandemics > Specific pandemics > Covid-19 > Health > Immunization

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    1. Stipic, Dorian & Bradac, Mislav & Lipic, Tomislav & Podobnik, Boris, 2021. "Effects of quarantine disobedience and mobility restrictions on COVID-19 pandemic waves in dynamical networks," Chaos, Solitons & Fractals, Elsevier, vol. 150(C).
    2. Vinicius Albani & Matheus Grasselli & Weijie Pang & Jorge P. Zubelli, 2022. "The Interplay between COVID-19 and the Economy in Canada," JRFM, MDPI, vol. 15(10), pages 1-26, October.
    3. Yongin Choi & James Slghee Kim & Jung Eun Kim & Heejin Choi & Chang Hyeong Lee, 2021. "Vaccination Prioritization Strategies for COVID-19 in Korea: A Mathematical Modeling Approach," IJERPH, MDPI, vol. 18(8), pages 1-19, April.

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