IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v16y2025i1d10.1038_s41467-025-61575-7.html
   My bibliography  Save this article

Learning interpretable network dynamics via universal neural symbolic regression

Author

Listed:
  • Jiao Hu

    (Jilin University
    Jilin University)

  • Jiaxu Cui

    (Jilin University
    Jilin University)

  • Bo Yang

    (Jilin University
    Jilin University)

Abstract

Discovering governing equations of complex network dynamics is a fundamental challenge in contemporary science with rich data, which can uncover the hidden patterns and mechanisms of the formation and evolution of complex phenomena in various fields and assist in decision-making. In this work, we develop a universal computational tool that can automatically, efficiently, and accurately learn the symbolic patterns of changes in complex system states by combining the excellent fitting capability of deep learning with the equation inference ability of pre-trained symbolic regression. We perform extensive and intensive experimental verifications on more than ten representative scenarios from fields such as physics, biochemistry, ecology, and epidemiology. The results demonstrate the remarkable effectiveness and efficiency of our tool compared to state-of-the-art symbolic regression techniques for network dynamics. The application to real-world systems including global epidemic transmission and pedestrian movements has verified its practical applicability. We believe that our tool can serve as a universal solution to dispel the fog of hidden mechanisms of changes in complex phenomena, advance toward interpretability, and inspire further scientific discoveries.

Suggested Citation

  • Jiao Hu & Jiaxu Cui & Bo Yang, 2025. "Learning interpretable network dynamics via universal neural symbolic regression," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
  • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-61575-7
    DOI: 10.1038/s41467-025-61575-7
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-025-61575-7
    File Function: Abstract
    Download Restriction: no

    File URL: https://libkey.io/10.1038/s41467-025-61575-7?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Jianxi Gao & Baruch Barzel & Albert-László Barabási, 2016. "Erratum: Universal resilience patterns in complex networks," Nature, Nature, vol. 536(7615), pages 238-238, August.
    2. Jianxi Gao & Baruch Barzel & Albert-László Barabási, 2016. "Universal resilience patterns in complex networks," Nature, Nature, vol. 530(7590), pages 307-312, February.
    3. Ting-Ting Gao & Baruch Barzel & Gang Yan, 2024. "Learning interpretable dynamics of stochastic complex systems from experimental data," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    4. Zhao Chen & Yang Liu & Hao Sun, 2021. "Physics-informed learning of governing equations from scarce data," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
    5. Patrick A. K. Reinbold & Logan M. Kageorge & Michael F. Schatz & Roman O. Grigoriev, 2021. "Robust learning from noisy, incomplete, high-dimensional experimental data via physically constrained symbolic regression," Nature Communications, Nature, vol. 12(1), pages 1-8, December.
    6. Lucas Böttcher & Nino Antulov-Fantulin & Thomas Asikis, 2022. "AI Pontryagin or how artificial neural networks learn to control dynamical systems," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    7. Gang Yan & Petra E. Vértes & Emma K. Towlson & Yee Lian Chew & Denise S. Walker & William R. Schafer & Albert-László Barabási, 2017. "Network control principles predict neuron function in the Caenorhabditis elegans connectome," Nature, Nature, vol. 550(7677), pages 519-523, October.
    8. Massimo Bernaschi & Isidoro González-Adalid Pemartín & Víctor Martín-Mayor & Giorgio Parisi, 2024. "The quantum transition of the two-dimensional Ising spin glass," Nature, Nature, vol. 631(8022), pages 749-754, July.
    9. Alex Davies & Petar Veličković & Lars Buesing & Sam Blackwell & Daniel Zheng & Nenad Tomašev & Richard Tanburn & Peter Battaglia & Charles Blundell & András Juhász & Marc Lackenby & Geordie Williamson, 2021. "Advancing mathematics by guiding human intuition with AI," Nature, Nature, vol. 600(7887), pages 70-74, December.
    10. Loïc Paulevé & Juri Kolčák & Thomas Chatain & Stefan Haar, 2020. "Publisher Correction: Reconciling qualitative, abstract, and scalable modeling of biological networks," Nature Communications, Nature, vol. 11(1), pages 1-2, December.
    11. Yuchen Zhang & Mingsheng Long & Kaiyuan Chen & Lanxiang Xing & Ronghua Jin & Michael I. Jordan & Jianmin Wang, 2023. "Skilful nowcasting of extreme precipitation with NowcastNet," Nature, Nature, vol. 619(7970), pages 526-532, July.
    12. Jean-Charles Delvenne & Renaud Lambiotte & Luis E. C. Rocha, 2015. "Diffusion on networked systems is a question of time or structure," Nature Communications, Nature, vol. 6(1), pages 1-10, November.
    13. Charles Murphy & Edward Laurence & Antoine Allard, 2021. "Deep learning of contagion dynamics on complex networks," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    14. Loïc Paulevé & Juri Kolčák & Thomas Chatain & Stefan Haar, 2020. "Reconciling qualitative, abstract, and scalable modeling of biological networks," Nature Communications, Nature, vol. 11(1), pages 1-7, December.
    15. Baruch Barzel & Yang-Yu Liu & Albert-László Barabási, 2015. "Constructing minimal models for complex system dynamics," Nature Communications, Nature, vol. 6(1), pages 1-8, November.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Zhuoming, Ren & Wan, Wang & Yu, Lin & Li, Zhao, 2024. "Modeling complex network perturbations on resilience of the bilateral regional trade agreements," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 655(C).
    2. Tu, Chengyi & Fan, Ying & Shi, Tianyu, 2024. "Dimensionality reduction of networked systems with separable coupling-dynamics: Theory and applications," Chaos, Solitons & Fractals, Elsevier, vol. 182(C).
    3. Chao, Xiangrui & Ran, Qin & Chen, Jia & Li, Tie & Qian, Qian & Ergu, Daji, 2022. "Regulatory technology (Reg-Tech) in financial stability supervision: Taxonomy, key methods, applications and future directions," International Review of Financial Analysis, Elsevier, vol. 80(C).
    4. Duan, Dongli & Wu, Xixi & Bai, Xue & Yan, Qi & Lv, Changchun & Bian, Genqing, 2022. "Dimensionality reduction method of dynamic networks for evolutionary mechanism of neuronal systems," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 599(C).
    5. Chang Liu & Fengli Xu & Chen Gao & Zhaocheng Wang & Yong Li & Jianxi Gao, 2024. "Deep learning resilience inference for complex networked systems," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    6. Lv, Changchun & Yuan, Ziwei & Si, Shubin & Duan, Dongli, 2021. "Robustness of scale-free networks with dynamical behavior against multi-node perturbation," Chaos, Solitons & Fractals, Elsevier, vol. 152(C).
    7. Zhao Li & Ren Zhuoming & Zhao Ziyi & Weng Tongfeng, 2024. "Topological perturbations on resilience of the world trade competition network," Palgrave Communications, Palgrave Macmillan, vol. 11(1), pages 1-9, December.
    8. Yingqiu Zhu & Ruiyi Wang & Mingfei Feng & Lei Qin & Ben-Chang Shia & Ming-Chih Chen, 2024. "Supply Chain Analysis Based on Community Detection of Multi-Layer Weighted Networks," Mathematics, MDPI, vol. 12(22), pages 1-21, November.
    9. Liang, Zhenglin & Li, Yan-Fu, 2023. "Holistic Resilience and Reliability Measures for Cellular Telecommunication Networks," Reliability Engineering and System Safety, Elsevier, vol. 237(C).
    10. Dongli, Duan & Chengxing, Wu & Yuchen, Zhai & Changchun, Lv & Ning, Wang, 2022. "Coexistence mechanism of alien species and local ecosystem based on network dimensionality reduction method," Chaos, Solitons & Fractals, Elsevier, vol. 159(C).
    11. Richard L. Gruner & Damien Power, 2023. "Conceptual wanderlust: How to develop creative supply chain theory with analogies," Journal of Supply Chain Management, Institute for Supply Management, vol. 59(4), pages 3-21, October.
    12. Sebestyén, Tamás & Szabó, Norbert & Braun, Emese & Bedő, Zsolt, 2024. "Lokális reziliencia számítása térbeli általános egyensúlyi modell felhasználásával [Measuring local resilience with a spatial computable general equilibrium model]," Közgazdasági Szemle (Economic Review - monthly of the Hungarian Academy of Sciences), Közgazdasági Szemle Alapítvány (Economic Review Foundation), vol. 0(11), pages 1222-1253.
    13. Gangwal, Utkarsh & Singh, Mayank & Pandey, Pradumn Kumar & Kamboj, Deepak & Chatterjee, Samrat & Bhatia, Udit, 2022. "Identifying early-warning indicators of onset of sudden collapse in networked infrastructure systems against sequential disruptions," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 591(C).
    14. Yang Ye & Abhishek Pandey & Carolyn Bawden & Dewan Md. Sumsuzzman & Rimpi Rajput & Affan Shoukat & Burton H. Singer & Seyed M. Moghadas & Alison P. Galvani, 2025. "Integrating artificial intelligence with mechanistic epidemiological modeling: a scoping review of opportunities and challenges," Nature Communications, Nature, vol. 16(1), pages 1-18, December.
    15. Cécile Bastidon & Antoine Parent, 2024. "Cliometrics of world stock markets evolving networks," Annals of Operations Research, Springer, vol. 332(1), pages 23-53, January.
    16. Meng, Xiangyi & Zhou, Bin, 2023. "Scale-free networks beyond power-law degree distribution," Chaos, Solitons & Fractals, Elsevier, vol. 176(C).
    17. Chunheng Jiang & Zhenhan Huang & Tejaswini Pedapati & Pin-Yu Chen & Yizhou Sun & Jianxi Gao, 2024. "Network properties determine neural network performance," Nature Communications, Nature, vol. 15(1), pages 1-9, December.
    18. Alejandro Martínez-Calvo & Matthew D. Biviano & Anneline H. Christensen & Eleni Katifori & Kaare H. Jensen & Miguel Ruiz-García, 2024. "The fluidic memristor as a collective phenomenon in elastohydrodynamic networks," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    19. Che, Yiming & Zhang, Ziang (John) & Cheng, Changqing, 2023. "Physical–statistical learning in resilience assessment for power generation systems," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 615(C).
    20. Aura Reggiani, 2022. "The Architecture of Connectivity: A Key to Network Vulnerability, Complexity and Resilience," Networks and Spatial Economics, Springer, vol. 22(3), pages 415-437, September.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-61575-7. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.