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Robust optimization model for integrated procurement, production and distribution in platelet supply chain

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  • Ensafian, Hamidreza
  • Yaghoubi, Saeed

Abstract

This paper presents an integrated platelet supply chain where demand is age-differentiated according to the type of patient. At first, considering the apheresis method and traditional production platelet method, two mixed-integer programming models are developed based on FIFO and LIFO issuing policies. Since in practice fresh platelets have been preferred, a bi-objective model has been then developed in which the first objective maximizes the freshness of the units delivered and the second minimizes the total cost. To cope with uncertain demand, a robust optimization approach is presented and the application of the proposed model is discussed in a case study.

Suggested Citation

  • Ensafian, Hamidreza & Yaghoubi, Saeed, 2017. "Robust optimization model for integrated procurement, production and distribution in platelet supply chain," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 103(C), pages 32-55.
    • Handle: RePEc:eee:transe:v:103:y:2017:i:c:p:32-55
    DOI: 10.1016/j.tre.2017.04.005
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