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Institutionalizing technoscience: Post-genomic technologies and the case of systems biology

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  • Styhre, Alexander

Abstract

Somewhat counter-intuitively, new drug development productivity has fallen at major pharmaceutical companies during the period of swift growth in scientific know-how during the last two decades. After substantial hype, genomics has been complemented by post-genomic technologies serving as the new hope for the future in terms of producing new therapies. Such post-genomic technologies, including systems biology and other biocomputational and bioinformatics approaches, are embedded in institutional logics both drawing on shared or idiosyncratic enactments of historical conditions and expectations for the future. This paper reports on a study based on interviews with scientists at a major pharmaceutical company, three biotechnology firms, and two academic research universities, suggesting that technoscientific approaches and frameworks are embedded in rhetoric advancing institutional logics constituting the organizing principles that shape the behavior of the actors in a field. Such rhetoric consists of narratives combining accounts of practices and their merits and shortcomings, beliefs, professional ideologies, and historical accomplishments.

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  • Styhre, Alexander, 2011. "Institutionalizing technoscience: Post-genomic technologies and the case of systems biology," Scandinavian Journal of Management, Elsevier, vol. 27(4), pages 375-388.
  • Handle: RePEc:eee:scaman:v:27:y:2011:i:4:p:375-388
    DOI: 10.1016/j.scaman.2011.06.001
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    1. Samuel, Sajay & Dirsmith, Mark W. & McElroy, Barbara, 2005. "Monetized medicine: from the physical to the fiscal," Accounting, Organizations and Society, Elsevier, vol. 30(3), pages 249-278, April.
    2. Caroline A. Bartel & Raghu Garud, 2009. "The Role of Narratives in Sustaining Organizational Innovation," Organization Science, INFORMS, vol. 20(1), pages 107-117, February.
    3. Casper, Steven & Matraves, Catherine, 2003. "Institutional frameworks and innovation in the German and UK pharmaceutical industry," Research Policy, Elsevier, vol. 32(10), pages 1865-1879, December.
    4. Rosenberg, Nathan, 1976. "On Technological Expectations," Economic Journal, Royal Economic Society, vol. 86(343), pages 523-535, September.
    5. Murray, Fiona, 2002. "Innovation as co-evolution of scientific and technological networks: exploring tissue engineering," Research Policy, Elsevier, vol. 31(8-9), pages 1389-1403, December.
    6. Lounsbury, Michael, 2008. "Institutional rationality and practice variation: New directions in the institutional analysis of practice," Accounting, Organizations and Society, Elsevier, vol. 33(4-5), pages 349-361.
    7. Madeleine Akrich & Michel Callon & Bruno Latour & Adrian Monaghan, 2002. "The Key To Success In Innovation Part Ii: The Art Of Choosing Good Spokespersons," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 6(02), pages 207-225.
    8. Rodolphe Durand & Hayagreeva Rao & Philippe Monin, 2003. "Institutional Change in Toque Ville: Nouvelle Cuisine as an Identity Movement in French Gastronomy," Post-Print hal-00480858, HAL.
    9. Simcha Jong, 2006. "How organizational structures in science shape spin-off firms: the biochemistry departments of Berkeley, Stanford, and UCSF and the birth of the biotech industry," Industrial and Corporate Change, Oxford University Press, vol. 15(2), pages 251-283, April.
    10. Jeffrey L. Furman & Megan MacGarvie, 2009. "Academic collaboration and organizational innovation: the development of research capabilities in the US pharmaceutical industry, 1927--1946," Industrial and Corporate Change, Oxford University Press, vol. 18(5), pages 929-961, October.
    11. Donald MacKenzie, 2006. "An Engine, Not a Camera: How Financial Models Shape Markets," MIT Press Books, The MIT Press, edition 1, volume 1, number 0262134608, December.
    12. Elizabeth Goodrick & Trish Reay, 2010. "Florence Nightingale Endures: Legitimizing a New Professional Role Identity," Journal of Management Studies, Wiley Blackwell, vol. 47(1), pages 55-84, January.
    13. Hayagreeva Rao & Philippe Monin & Rodolphe Durand, 2003. "Institutional change in toque ville : Nouvelle cuisine as an identity movement in French gastronomy," Post-Print hal-02311672, HAL.
    14. Wanda J. Orlikowski & JoAnne Yates, 2002. "It's About Time: Temporal Structuring in Organizations," Organization Science, INFORMS, vol. 13(6), pages 684-700, December.
    15. Madeleine Akrich & Michel Callon & Bruno Latour & Adrian Monaghan, 2002. "The Key To Success In Innovation Part I: The Art Of Interessement," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 6(02), pages 187-206.
    16. Jason Owen-Smith & Walter W. Powell, 2004. "Knowledge Networks as Channels and Conduits: The Effects of Spillovers in the Boston Biotechnology Community," Organization Science, INFORMS, vol. 15(1), pages 5-21, February.
    17. Mats Alvesson, 1993. "Organizations As Rhetoric: Knowledge‐Intensive Firms And The Struggle With Ambiguity," Journal of Management Studies, Wiley Blackwell, vol. 30(6), pages 997-1015, November.
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    1. Wu, Qiang & He, Qile, 2020. "DIY Laboratories and business innovation ecosystems: The case of pharmaceutical industry," Technological Forecasting and Social Change, Elsevier, vol. 161(C).

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