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Finite mixture representations of zero-and-N-inflated distributions for count-compositional data

Author

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  • Menezes, André F.B.
  • Parnell, Andrew C.
  • Murphy, Keefe

Abstract

We provide novel probabilistic portrayals of two multivariate models designed to handle zero-inflation in count-compositional data. We develop a new unifying framework that represents both as finite mixture distributions. One of these distributions, based on Dirichlet-multinomial components, has been studied before, but has not yet been properly characterised as a sampling distribution of the counts. The other, based on multinomial components, is a new contribution. Using our finite mixture representations enables us to derive key statistical properties, including moments, marginal distributions, and special cases for both distributions. We develop enhanced Bayesian inference schemes with efficient Gibbs sampling updates, wherever possible, for parameters and auxiliary variables, demonstrating improvements over existing methods in the literature. We conduct simulation studies to evaluate the efficiency of the Bayesian inference procedures and present applications to a human gut microbiome dataset to illustrate the practical utility of the proposed distributions.

Suggested Citation

  • Menezes, André F.B. & Parnell, Andrew C. & Murphy, Keefe, 2025. "Finite mixture representations of zero-and-N-inflated distributions for count-compositional data," Journal of Multivariate Analysis, Elsevier, vol. 210(C).
  • Handle: RePEc:eee:jmvana:v:210:y:2025:i:c:s0047259x25000879
    DOI: 10.1016/j.jmva.2025.105492
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    References listed on IDEAS

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    1. Morris, Darcy Steeg & Raim, Andrew M. & Sellers, Kimberly F., 2020. "A Conway–Maxwell-multinomial distribution for flexible modeling of clustered categorical data," Journal of Multivariate Analysis, Elsevier, vol. 179(C).
    2. Matthew D. Koslovsky, 2023. "A Bayesian zero‐inflated Dirichlet‐multinomial regression model for multivariate compositional count data," Biometrics, The International Biometric Society, vol. 79(4), pages 3239-3251, December.
    3. Yanyan Zeng & Daolin Pang & Hongyu Zhao & Tao Wang, 2023. "A Zero-Inflated Logistic Normal Multinomial Model for Extracting Microbial Compositions," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 118(544), pages 2356-2369, October.
    4. Frank Tuyl, 2019. "A Method to Handle Zero Counts in the Multinomial Model," The American Statistician, Taylor & Francis Journals, vol. 73(2), pages 151-158, April.
    5. Dianliang Deng & Yu Zhang, 2015. "Score Tests for Both Extra Zeros and Extra Ones in Binomial Mixed Regression Models," Communications in Statistics - Theory and Methods, Taylor & Francis Journals, vol. 44(14), pages 2881-2897, July.
    6. Tian, Guo-Liang & Ma, Huijuan & Zhou, Yong & Deng, Dianliang, 2015. "Generalized endpoint-inflated binomial model," Computational Statistics & Data Analysis, Elsevier, vol. 89(C), pages 97-114.
    7. Puig, Pedro & Valero, Jordi, 2006. "Count Data Distributions: Some Characterizations With Applications," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 332-340, March.
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