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Science-Technology Linkages in an Emerging Research Platform: The case of Combinatorial Chemistry and Biology

Listed author(s):
  • Malo Stéphane
  • Geuna Aldo

    (MERIT)

This article focuses on issues concerning science and technology relationships posed by the emergence of a new drug discovery method, namely, combinatorial chemistry and biology. We assess the scientific content of combinatorial chemistry and biology using citations in patents to scientific journals and compare this research platform with biotechnology. We also identify the institutional affiliation of all the authors of the cited papers, which leads us to an analysis of knowledge spillovers between the main participants in the research network. Finally, we examine the relevance of localisation in the process of knowledge exchange with regard to EU countries and the US. The result of the analysis provide evidence to support the view that the inventive capacity of a country is dependent upon the basic research which is carried out, especially in universities and public research centres located in the inventor''s country.

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File URL: http://digitalarchive.maastrichtuniversity.nl/fedora/objects/guid:a5e4c989-b73f-4087-9417-c0970b7f6da9/datastreams/ASSET1/content
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Paper provided by Maastricht University, Maastricht Economic Research Institute on Innovation and Technology (MERIT) in its series Research Memorandum with number 020.

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Date of creation: 1999
Handle: RePEc:unm:umamer:1999020
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  1. van Vianen, B. G. & Moed, H. F. & van Raan, A. F. J., 1990. "An exploration of the science base of recent technology," Research Policy, Elsevier, vol. 19(1), pages 61-81, February.
  2. Collins, Peter & Wyatt, Suzanne, 1988. "Citations in patents to the basic research literature," Research Policy, Elsevier, vol. 17(2), pages 65-74, April.
  3. Adam B. Jaffe & Manuel Trajtenberg & Rebecca Henderson, 1993. "Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations," The Quarterly Journal of Economics, Oxford University Press, vol. 108(3), pages 577-598.
  4. Nathan ROSENBERG, 2009. "Why do firms do basic research (with their own money)?," World Scientific Book Chapters,in: Studies On Science And The Innovation Process Selected Works of Nathan Rosenberg, chapter 11, pages 225-234 World Scientific Publishing Co. Pte. Ltd..
  5. Narin, Francis & Olivastro, Dominic, 1992. "Status report: Linkage between technology and science," Research Policy, Elsevier, vol. 21(3), pages 237-249, June.
  6. Thomke, Stefan & von Hippel, Eric & Franke, Roland, 1998. "Modes of experimentation: an innovation process--and competitive--variable," Research Policy, Elsevier, vol. 27(3), pages 315-332, July.
  7. Jaffe, Adam B, 1989. "Real Effects of Academic Research," American Economic Review, American Economic Association, vol. 79(5), pages 957-970, December.
  8. Narin, Francis & Hamilton, Kimberly S. & Olivastro, Dominic, 1997. "The increasing linkage between U.S. technology and public science," Research Policy, Elsevier, vol. 26(3), pages 317-330, October.
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